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ES2149515T3 - METHODS FOR THE SELECTIVE SEPARATION OF ORGANIC COMPONENTS FROM BIOLOGICAL FLUIDS. - Google Patents

METHODS FOR THE SELECTIVE SEPARATION OF ORGANIC COMPONENTS FROM BIOLOGICAL FLUIDS.

Info

Publication number
ES2149515T3
ES2149515T3 ES96944412T ES96944412T ES2149515T3 ES 2149515 T3 ES2149515 T3 ES 2149515T3 ES 96944412 T ES96944412 T ES 96944412T ES 96944412 T ES96944412 T ES 96944412T ES 2149515 T3 ES2149515 T3 ES 2149515T3
Authority
ES
Spain
Prior art keywords
methods
organic components
blood
selective separation
biological fluids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96944412T
Other languages
Spanish (es)
Inventor
Randall S Kent
William N Drohan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American National Red Cross
Original Assignee
American National Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American National Red Cross filed Critical American National Red Cross
Application granted granted Critical
Publication of ES2149515T3 publication Critical patent/ES2149515T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention pertains to improved methods for the selective separation of organic components from biological fluids. More particularly, the present invention pertains to methods for the selective separation of organic components from biological fluids which comprise the step of contacting the biological fluid with a synthetic hydrated alkaline earth silicate (i.e., SHAES), such as synthetic hydrated calcium silicate (i.e., SHCS) or synthetic hydrated magnesium silicate (i.e., SHMS). In a preferred embodiment, the present invention pertains to such methods where the biological fluid is a mammalian blood fluid (e.g., whole blood, blood plasma, blood serum, blood fraction, plasma fraction, serum fraction).
ES96944412T 1996-07-10 1996-12-20 METHODS FOR THE SELECTIVE SEPARATION OF ORGANIC COMPONENTS FROM BIOLOGICAL FLUIDS. Expired - Lifetime ES2149515T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2154596P 1996-07-10 1996-07-10
PCT/US1996/020034 WO1998001464A1 (en) 1996-07-10 1996-12-20 Methods for the selective separation of organic components from biological fluids

Publications (1)

Publication Number Publication Date
ES2149515T3 true ES2149515T3 (en) 2000-11-01

Family

ID=21804845

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96944412T Expired - Lifetime ES2149515T3 (en) 1996-07-10 1996-12-20 METHODS FOR THE SELECTIVE SEPARATION OF ORGANIC COMPONENTS FROM BIOLOGICAL FLUIDS.

Country Status (8)

Country Link
US (1) US6193891B1 (en)
EP (1) EP0915906B1 (en)
AT (1) ATE196148T1 (en)
AU (1) AU1422597A (en)
DE (1) DE69610227T2 (en)
DK (1) DK0915906T3 (en)
ES (1) ES2149515T3 (en)
WO (1) WO1998001464A1 (en)

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AUPN030794A0 (en) 1994-12-22 1995-01-27 Aruba International Pty Ltd Discontinuous plasma or serum delipidation
US20020012990A1 (en) * 1999-12-22 2002-01-31 Lander Russel Jackson Process for the scaleable purification of plasmid DNA
PT1242442E (en) * 1999-12-22 2007-11-08 Merck & Co Inc Process for the scaleable purification of plasmid dna
US8597516B2 (en) * 2000-05-16 2013-12-03 Immunocept, L.L.C. Methods and systems for colloid exchange therapy
US7407663B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified immunodeficiency virus particles
US7407662B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified viral particles with immunogenic properties and reduced lipid content
US7439052B2 (en) * 2000-06-29 2008-10-21 Lipid Sciences Method of making modified immunodeficiency virus particles
AUPQ846900A0 (en) * 2000-06-29 2000-07-27 Aruba International Pty Ltd A vaccine
US20090017069A1 (en) * 2000-06-29 2009-01-15 Lipid Sciences, Inc. SARS Vaccine Compositions and Methods of Making and Using Them
US20020164825A1 (en) * 2000-09-09 2002-11-07 Wen-Tien Chen Cell separation matrix
US6506308B1 (en) * 2000-09-12 2003-01-14 Advanced Minerals Corporation Methods for the removal of organic substances from aqueous solutions
WO2002092161A1 (en) * 2001-05-10 2002-11-21 Biophan, Llc Miniaturized particle analyzer
JP2004532709A (en) * 2001-06-25 2004-10-28 リピド サイエンスィズ インコーポレイテッド Systems and methods using solvents for removing lipids from fluids
US20030127386A1 (en) * 2001-06-25 2003-07-10 Bomberger David C. Hollow fiber contactor systems for removal of lipids from fluids
US6991727B2 (en) * 2001-06-25 2006-01-31 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
US20060060520A1 (en) * 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
WO2003000381A1 (en) * 2001-06-25 2003-01-03 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
WO2003035888A1 (en) * 2001-08-28 2003-05-01 Wen-Tien Chen Cell separation matrix
ATE382670T1 (en) * 2001-10-04 2008-01-15 Toray Industries HYDROPHILIC MATERIAL AND METHOD FOR PRODUCING IT
US20030201229A1 (en) * 2002-02-04 2003-10-30 Martin Siwak Process for prefiltration of a protein solution
WO2003066669A2 (en) * 2002-02-04 2003-08-14 Millipore Corporation Process for removing protein aggregates and virus from a protein solution
WO2004017946A1 (en) * 2002-08-26 2004-03-04 Lipid Sciences, Inc. Treating alzheimers using delipidated protein particles
US20050042772A1 (en) * 2003-02-07 2005-02-24 Beyond Genomics Removal of proteins from a sample
US20040245124A1 (en) * 2003-06-03 2004-12-09 Hurst William E. Preformed mixing bag for dry powder, apparatus, method and system for using same
US20040245144A1 (en) * 2003-06-03 2004-12-09 Hurst William E. Preformed mixing bag for dry powder, apparatus, method and system for using same
AU2004260632A1 (en) * 2003-07-03 2005-02-10 Lipid Sciences Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
US7393826B2 (en) * 2003-07-03 2008-07-01 Lipid Sciences, Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
US6960803B2 (en) * 2003-10-23 2005-11-01 Silicon Storage Technology, Inc. Landing pad for use as a contact to a conductive spacer
FR2869995B1 (en) * 2004-05-10 2006-09-22 Sebia Sa IMPROVED CAPILLARY ELECTROPHORESIS PROTEIN SEPARATION PROCESS AND CAPILLARY ELECTROPHORESIS BUFFER COMPOSITIONS
US20080028989A1 (en) * 2006-07-20 2008-02-07 Scott Kevin Palm Process for removing organic contaminants from non-metallic inorganic materials using dielectric heating
US20080119350A1 (en) * 2006-11-20 2008-05-22 Korea Institute Of Geosciences And Mineral Resources Ion exchange type lithium adsorbent using filter and method for preparing the same
US8835104B2 (en) 2007-12-20 2014-09-16 Fenwal, Inc. Medium and methods for the storage of platelets
US7959809B2 (en) 2007-12-28 2011-06-14 Baxter International Inc. Counter-pressure filtration of proteins
EP2652491B1 (en) 2010-12-15 2017-11-29 Baxalta GmbH Eluate collection using conductivity gradient
EP2694131B1 (en) 2011-04-07 2019-08-28 Fenwal, Inc. Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates
KR101446265B1 (en) * 2011-10-17 2014-11-03 메디칸(주) Bio-Fat material eliminated immunity
DE102014210662A1 (en) 2014-06-04 2015-12-17 Gea Westfalia Separator Group Gmbh Apparatus and method for obtaining glycoglycerolipids and glycosphingolipids from lipoid phases
CN105153297B (en) * 2015-09-17 2020-03-31 中国人民解放军军事医学科学院野战输血研究所 Method for separating and purifying α 2-macroglobulin from Cohn component IV precipitate
EP3362464B1 (en) * 2015-10-15 2021-04-28 Plasma Technologies LLC Methods for extracting proteins from blood plasma
JP7550448B2 (en) 2017-11-22 2024-09-13 エイチディーエル セラピューティクス インコーポレイテッド System and method for priming a fluid circuit of a plasma processing system - Patents.com
WO2019133358A2 (en) 2017-12-28 2019-07-04 Hdl Therapeutics, Inc. Methods for preserving and administering pre-beta high density lipoprotein extracted from human plasma
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
KR20220111307A (en) * 2019-12-03 2022-08-09 옴릭스 바이오파머슈티컬스 리미티드 Pro-thrombin Tablets

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JPS5327491A (en) * 1976-08-26 1978-03-14 Terumo Corp Separation and refining process for red corpuscle
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Also Published As

Publication number Publication date
EP0915906A1 (en) 1999-05-19
DE69610227D1 (en) 2000-10-12
EP0915906B1 (en) 2000-09-06
US6193891B1 (en) 2001-02-27
ATE196148T1 (en) 2000-09-15
AU1422597A (en) 1998-02-02
DK0915906T3 (en) 2000-11-20
WO1998001464A1 (en) 1998-01-15
DE69610227T2 (en) 2001-01-04

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