ES2141384T3 - Fabricacion de levobupivacaina y analogos de la misma a partir de l-lisina. - Google Patents
Fabricacion de levobupivacaina y analogos de la misma a partir de l-lisina.Info
- Publication number
- ES2141384T3 ES2141384T3 ES95933512T ES95933512T ES2141384T3 ES 2141384 T3 ES2141384 T3 ES 2141384T3 ES 95933512 T ES95933512 T ES 95933512T ES 95933512 T ES95933512 T ES 95933512T ES 2141384 T3 ES2141384 T3 ES 2141384T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- levobupivacaine
- lysine
- analogs
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
SE PREPARA UN NUEVO COMPUESTO DE FORMULA (X) A PARTIR DE LLISINA, Y SE CONVIERTE EN LEVOBUPIVACAINA MEDIANTE PRODUCCION EN CICLOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9420243A GB9420243D0 (en) | 1994-10-07 | 1994-10-07 | Complex and its use |
GBGB9504928.4A GB9504928D0 (en) | 1995-03-10 | 1995-03-10 | Diazotisation and cyclisation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2141384T3 true ES2141384T3 (es) | 2000-03-16 |
Family
ID=26305755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95933512T Expired - Lifetime ES2141384T3 (es) | 1994-10-07 | 1995-10-09 | Fabricacion de levobupivacaina y analogos de la misma a partir de l-lisina. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5929242A (es) |
EP (1) | EP0784608B1 (es) |
JP (1) | JP3970925B2 (es) |
AT (1) | ATE187958T1 (es) |
AU (1) | AU695348B2 (es) |
DE (1) | DE69514115T2 (es) |
ES (1) | ES2141384T3 (es) |
MX (1) | MX9702486A (es) |
WO (1) | WO1996011181A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2234975T3 (pl) | 2008-01-15 | 2012-09-28 | Pharmathen Sa | Proces wytwarzania 2',6'-ksylidydu kwasu 2-pipekolinowego stosowanego jako produkt pośredni do przygotowywania środków miejscowo znieczulających |
CN111548303A (zh) * | 2020-06-28 | 2020-08-18 | 山东美泰医药有限公司 | 一种盐酸左布比卡因的杂质及其制备和分析方法 |
-
1995
- 1995-10-09 JP JP51243396A patent/JP3970925B2/ja not_active Expired - Fee Related
- 1995-10-09 AT AT95933512T patent/ATE187958T1/de not_active IP Right Cessation
- 1995-10-09 DE DE69514115T patent/DE69514115T2/de not_active Expired - Lifetime
- 1995-10-09 AU AU36142/95A patent/AU695348B2/en not_active Ceased
- 1995-10-09 US US08/817,460 patent/US5929242A/en not_active Expired - Lifetime
- 1995-10-09 WO PCT/GB1995/002385 patent/WO1996011181A1/en active IP Right Grant
- 1995-10-09 MX MX9702486A patent/MX9702486A/es unknown
- 1995-10-09 ES ES95933512T patent/ES2141384T3/es not_active Expired - Lifetime
- 1995-10-09 EP EP95933512A patent/EP0784608B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
MX9702486A (es) | 1998-04-30 |
WO1996011181A1 (en) | 1996-04-18 |
ATE187958T1 (de) | 2000-01-15 |
JPH10507173A (ja) | 1998-07-14 |
EP0784608B1 (en) | 1999-12-22 |
AU695348B2 (en) | 1998-08-13 |
EP0784608A1 (en) | 1997-07-23 |
AU3614295A (en) | 1996-05-02 |
JP3970925B2 (ja) | 2007-09-05 |
US5929242A (en) | 1999-07-27 |
DE69514115T2 (de) | 2000-04-20 |
DE69514115D1 (de) | 2000-01-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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