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ES2001875A6 - Procedimiento para preparar nuevos derivados de aminoacidos - Google Patents

Procedimiento para preparar nuevos derivados de aminoacidos

Info

Publication number
ES2001875A6
ES2001875A6 ES8601245A ES8601245A ES2001875A6 ES 2001875 A6 ES2001875 A6 ES 2001875A6 ES 8601245 A ES8601245 A ES 8601245A ES 8601245 A ES8601245 A ES 8601245A ES 2001875 A6 ES2001875 A6 ES 2001875A6
Authority
ES
Spain
Prior art keywords
amino acid
acid derivatives
preparation
cardioprotection
definitions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601245A
Other languages
English (en)
Inventor
Gerd Schnorrenberg
Otto Roos
Walter Losel
Ingrid Wiedemann
Wolfram Gaida
Wolfram Hoefke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Publication of ES2001875A6 publication Critical patent/ES2001875A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

EL PROCEDIMIENTO DESCRITO PREPARA COMPUESTOS DE FORMULA DONDE R1 Y R2 SON HIDROGENO O ALQUILO, R3 ES HIDROGENO, ALQUILO O ACILO, W ES OXIGENO, AZUFRE O NH, M Y N SON 0-2, K ES 1-4, X, Y Y Z SON OXIGENO, AZUFRE O RADICALES ORGANICOS, HACIENDO REACCIONAR UN COMPUESTO DE FORMULA II CON UN COMPUESTO DE FORMULA III DONDE T Y U SON UN GRUPO NUCLEOFUGO O UN GRUPO AMINO, R7 ES HIDROGENO, ALQUILO, BENCILO O TRIMETILSILILO, R8 ES COMO R3 O UN GRUPO PROTECTOR Y LOS RESTANTES SIMBOLOS SON COMO ANTES. LA PREPARACION DE COMPUESTOS DE FORMULA I PUEDE EFECTUARSE TAMBIEN POR VIAS ALTERNATIVAS DESCRITAS EN LA MEMORIA. LOS COMPUESTOS OBTENIDOS SON UTILES PARA CARDIOPROTECCION Y TRATAMIENTO DE LA HIPERTENSION SANGUINEA.
ES8601245A 1985-08-22 1986-08-21 Procedimiento para preparar nuevos derivados de aminoacidos Expired ES2001875A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853529960 DE3529960A1 (de) 1985-08-22 1985-08-22 Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung

Publications (1)

Publication Number Publication Date
ES2001875A6 true ES2001875A6 (es) 1988-07-01

Family

ID=6279053

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601245A Expired ES2001875A6 (es) 1985-08-22 1986-08-21 Procedimiento para preparar nuevos derivados de aminoacidos

Country Status (20)

Country Link
US (1) US5008273A (es)
EP (1) EP0213499A3 (es)
JP (1) JPS6245598A (es)
KR (1) KR870002145A (es)
AU (1) AU594969B2 (es)
DD (1) DD258609A5 (es)
DE (1) DE3529960A1 (es)
DK (1) DK398986A (es)
ES (1) ES2001875A6 (es)
FI (1) FI863358A (es)
GR (1) GR862183B (es)
HU (1) HU196434B (es)
IL (1) IL79792A (es)
NO (1) NO164982C (es)
NZ (1) NZ217310A (es)
PL (1) PL148493B1 (es)
PT (1) PT83239B (es)
SU (1) SU1544188A3 (es)
YU (1) YU146686A (es)
ZA (1) ZA866311B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3801587A1 (de) * 1988-01-21 1989-08-03 Hoechst Ag Neue aminosaeureglyceride, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
CA1340588C (en) * 1988-06-13 1999-06-08 Balraj Krishan Handa Amino acid derivatives
US5162336A (en) * 1990-06-21 1992-11-10 Rhone-Poulenc Rorer Pharmaceuticals Inc. Tetrahydro-pyrido-indoles as cholecystokinin and gastrin antagonists
US5688762A (en) * 1995-09-06 1997-11-18 Steiner; Zoltan W. Method of treating hypertension using animal stomach mucosa extract and endogenous protease-inhibitor peptides
US5922839A (en) * 1995-09-06 1999-07-13 Steiner; Zoltan W. Method of treating hypertension using a composition containing a dried animal stomach mucosa and endogenous protease-inhibitor peptides
US6323215B1 (en) * 1999-07-09 2001-11-27 Ortho-Mcneil Pharmaceutical, Inc. Neurotrophic tetrahydroisoquinolines and tetrahydrothienopyridines, and related compositions and methods
WO2006126087A2 (en) * 2005-05-27 2006-11-30 University Of Cape Town Angiotensin i-converting enzyme (ace) inhibitors
US7632796B2 (en) 2005-10-28 2009-12-15 Dynaloy, Llc Dynamic multi-purpose composition for the removal of photoresists and method for its use
US8263539B2 (en) * 2005-10-28 2012-09-11 Dynaloy, Llc Dynamic multi-purpose composition for the removal of photoresists and methods for its use
US9329486B2 (en) 2005-10-28 2016-05-03 Dynaloy, Llc Dynamic multi-purpose composition for the removal of photoresists and method for its use
TWI450052B (zh) * 2008-06-24 2014-08-21 Dynaloy Llc 用於後段製程操作有效之剝離溶液
US8987181B2 (en) 2011-11-08 2015-03-24 Dynaloy, Llc Photoresist and post etch residue cleaning solution
US9158202B2 (en) 2012-11-21 2015-10-13 Dynaloy, Llc Process and composition for removing substances from substrates
US9029268B2 (en) 2012-11-21 2015-05-12 Dynaloy, Llc Process for etching metals

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2487829A2 (fr) * 1979-12-07 1982-02-05 Science Union & Cie Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
DE19575012I2 (de) * 1980-10-23 2002-01-24 Schering Corp Carboxyalkyl-Dipeptide Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE3302125A1 (de) * 1983-01-22 1984-07-26 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung

Also Published As

Publication number Publication date
PT83239B (pt) 1989-03-30
HUT42505A (en) 1987-07-28
NO863373D0 (no) 1986-08-21
AU6169186A (en) 1987-02-26
NO863373L (no) 1987-02-23
IL79792A (en) 1990-11-05
IL79792A0 (en) 1986-11-30
DK398986D0 (da) 1986-08-21
US5008273A (en) 1991-04-16
KR870002145A (ko) 1987-03-30
ZA866311B (en) 1988-04-27
YU146686A (en) 1988-02-29
EP0213499A2 (de) 1987-03-11
AU594969B2 (en) 1990-03-22
DE3529960A1 (de) 1987-03-05
PL261087A1 (en) 1988-04-14
HU196434B (en) 1988-11-28
PT83239A (de) 1986-09-01
PL148493B1 (en) 1989-10-31
NZ217310A (en) 1990-01-29
DK398986A (da) 1987-02-23
JPS6245598A (ja) 1987-02-27
DD258609A5 (de) 1988-07-27
FI863358A0 (fi) 1986-08-20
NO164982B (no) 1990-08-27
FI863358A (fi) 1987-02-23
SU1544188A3 (ru) 1990-02-15
NO164982C (no) 1990-12-05
GR862183B (en) 1986-12-23
EP0213499A3 (de) 1989-08-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001204