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ES2098263T3 - 8-alfa-acilamino-ergolinas, su preparacion y su utilizacion como medicamentos. - Google Patents

8-alfa-acilamino-ergolinas, su preparacion y su utilizacion como medicamentos.

Info

Publication number
ES2098263T3
ES2098263T3 ES90906872T ES90906872T ES2098263T3 ES 2098263 T3 ES2098263 T3 ES 2098263T3 ES 90906872 T ES90906872 T ES 90906872T ES 90906872 T ES90906872 T ES 90906872T ES 2098263 T3 ES2098263 T3 ES 2098263T3
Authority
ES
Spain
Prior art keywords
alpha
ergolins
acilamino
medicines
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90906872T
Other languages
English (en)
Inventor
Gerhard Sauer
Thomas Brumby
Helmut Wachtel
Jonathan Turner
Peter Andreas Loschmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2098263T3 publication Critical patent/ES2098263T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SE DESCRIBEN COMPUESTOS DE LA FORMULA (I) EN LOS QUE R (AL CUADRADO) , R ELEVADO 6 Y R ELEVADO 8 TIENEN LOS SIGNIFICADOS DADOS EN LA DESCRIPCION, SU PREPARACION Y SU USO COMO MEDICAMENTOS.
ES90906872T 1989-05-12 1990-05-10 8-alfa-acilamino-ergolinas, su preparacion y su utilizacion como medicamentos. Expired - Lifetime ES2098263T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3915950A DE3915950A1 (de) 1989-05-12 1989-05-12 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ES2098263T3 true ES2098263T3 (es) 1997-05-01

Family

ID=6380759

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90906872T Expired - Lifetime ES2098263T3 (es) 1989-05-12 1990-05-10 8-alfa-acilamino-ergolinas, su preparacion y su utilizacion como medicamentos.

Country Status (14)

Country Link
US (2) US5212178A (es)
EP (1) EP0427827B1 (es)
JP (1) JPH04500681A (es)
AT (1) ATE147742T1 (es)
CA (1) CA2028832A1 (es)
CZ (2) CZ278981B6 (es)
DD (1) DD294259A5 (es)
DE (2) DE3915950A1 (es)
DK (1) DK0427827T3 (es)
ES (1) ES2098263T3 (es)
HU (1) HU212814B (es)
PT (1) PT94011B (es)
SK (2) SK233190A3 (es)
WO (1) WO1990013550A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6018332A (en) * 1997-11-21 2000-01-25 Ark Interface Ii, Inc. Overscan user interface
US8113807B2 (en) * 2007-08-24 2012-02-14 Timothy Wilkinson Methods and apparatus for fabricating structures
CA2859173A1 (en) * 2011-12-19 2013-06-27 Map Pharmaceuticals, Inc. Novel iso-ergoline derivatives
CN113149982A (zh) 2015-01-20 2021-07-23 Xoc制药股份有限公司 麦角灵化合物及其用途
EP3247357A4 (en) 2015-01-20 2018-07-11 Xoc Pharmaceuticals, Inc Isoergoline compounds and uses thereof
AU2018275873A1 (en) 2017-06-01 2019-12-19 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2864822A (en) * 1956-10-22 1958-12-16 Lilly Co Eli 9-amino-7-methyl-belta10-ergolene and derivatives thereof
CH615929A5 (en) * 1975-06-02 1980-02-29 Sandoz Ag Process for the preparation of novel ergoline compounds
CH654838A5 (fr) * 1980-07-25 1986-03-14 Sandoz Ag Ergolinderivate, verfahren zu deren herstellung, diese enthaltende pharmazeutische zusammensetzungen.
DE3135305C2 (de) * 1981-09-03 1983-07-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 8-Ergolinyl-harnstoffen
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
NL8400333A (nl) * 1983-02-16 1984-09-17 Sandoz Ag Moederkoornalkaloiden, hun bereiding en hun toepassing.
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
HU197569B (en) * 1984-01-12 1989-04-28 Sandoz Ag Process for producing 8alpha-acylaminoergoline derivatives and pharmaceuticals comprising such compounds
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
NL8503426A (nl) * 1984-12-24 1986-07-16 Sandoz Ag 8alfa-acylamino-ergolinen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
DE3544365A1 (de) * 1984-12-24 1986-07-03 Sandoz-Patent-GmbH, 7850 Lörrach 8(alpha)-acylaminoergoline
DE3528584A1 (de) * 1985-08-06 1987-02-19 Schering Ag Neue 1-alkyl-ergolin-thioharnstoffderivate
HUT45248A (en) * 1986-01-24 1988-06-28 Sandoz Ag Process for producing 8alpha-(acylamino)-ergoline derivatives and pharmaceuticals comprising such compounds
DE3700825A1 (de) * 1986-01-24 1987-07-30 Sandoz Ag 8(alpha)-acylaminoergoline, ihre herstellung und verwendung
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
DE3708028A1 (de) * 1987-03-10 1988-09-22 Schering Ag Verfahren zur herstellung von 2,3ss-dihydroergolinen, 2-substituierte 2,3ss-dihydroergoline und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
CZ233190A3 (en) 1994-02-16
US5547958A (en) 1996-08-20
ATE147742T1 (de) 1997-02-15
CA2028832A1 (en) 1990-11-13
WO1990013550A1 (de) 1990-11-15
SK277997B6 (en) 1995-09-13
DE3915950A1 (de) 1990-11-15
EP0427827A1 (de) 1991-05-22
DE59010633D1 (de) 1997-03-06
CZ279080B6 (en) 1994-12-15
HU904426D0 (en) 1991-07-29
SK233190A3 (en) 1995-09-13
US5212178A (en) 1993-05-18
CZ260491A3 (en) 1993-03-17
DD294259A5 (de) 1991-09-26
SK277996B6 (en) 1995-09-13
JPH04500681A (ja) 1992-02-06
PT94011B (pt) 1996-12-31
PT94011A (pt) 1991-01-08
CZ278981B6 (en) 1994-11-16
HU212814B (hu) 1998-08-28
DK0427827T3 (da) 1997-07-07
SK260491A3 (en) 1995-09-13
EP0427827B1 (de) 1997-01-15
HUT56363A (en) 1991-08-28

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