Nothing Special   »   [go: up one dir, main page]

ES2091765T3 - Procedimiento de deteccion e identificacion de constituyentes que contienen acido nucleico. - Google Patents

Procedimiento de deteccion e identificacion de constituyentes que contienen acido nucleico.

Info

Publication number
ES2091765T3
ES2091765T3 ES89311006T ES89311006T ES2091765T3 ES 2091765 T3 ES2091765 T3 ES 2091765T3 ES 89311006 T ES89311006 T ES 89311006T ES 89311006 T ES89311006 T ES 89311006T ES 2091765 T3 ES2091765 T3 ES 2091765T3
Authority
ES
Spain
Prior art keywords
detection
nucleic acid
containing nucleic
identification procedure
constituents containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89311006T
Other languages
English (en)
Inventor
Tsanyang Liang
Jack R Wands
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Application granted granted Critical
Publication of ES2091765T3 publication Critical patent/ES2091765T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761Hepatitis B
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804Nucleic acid analysis using immunogens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/705Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

ES DESCRITO UN METODO PARA LA DETECCION DE PARTES QUE CONTIENEN ACIDO NUCLEICO TALES COMO VIRUS O BACTERIAS QUE COMBINA LA CAPTURA DE AFINIDAD DE LA PARTE CON UN ANTICUERPO MONOCLONAL CON DETECCION E IDENTIFICACION DEL ACIDO NUCLEICO DE LA PARTE QUE USA TECNICAS DE AMPLIFICACION.
ES89311006T 1988-10-25 1989-10-25 Procedimiento de deteccion e identificacion de constituyentes que contienen acido nucleico. Expired - Lifetime ES2091765T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/262,347 US5077192A (en) 1988-10-25 1988-10-25 Method of detecting antigenic, nucleic acid-containing macromolecular entities

Publications (1)

Publication Number Publication Date
ES2091765T3 true ES2091765T3 (es) 1996-11-16

Family

ID=22997118

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89311006T Expired - Lifetime ES2091765T3 (es) 1988-10-25 1989-10-25 Procedimiento de deteccion e identificacion de constituyentes que contienen acido nucleico.

Country Status (8)

Country Link
US (2) US5077192A (es)
EP (1) EP0366448B1 (es)
JP (1) JPH02257899A (es)
AT (1) ATE141651T1 (es)
CA (1) CA1340249C (es)
DE (1) DE68926991T2 (es)
ES (1) ES2091765T3 (es)
IE (1) IE76455B1 (es)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077192A (en) * 1988-10-25 1991-12-31 The General Hospital Corporation Method of detecting antigenic, nucleic acid-containing macromolecular entities
IE64040B1 (en) * 1989-06-15 1995-06-28 Akzo Nv Method for determining nucleic acid
US5780219A (en) * 1989-07-11 1998-07-14 Gen-Probe Incorporated Nucleic acid amplification oligonucleotides and probes to human hepatitis B virus
WO1992004458A1 (en) * 1990-09-11 1992-03-19 The Brookdale Hospital Medical Center Drug resistance screening method
NL9002696A (nl) * 1990-11-15 1992-06-01 U Gene Research Bv Werkwijze en kit voor het aantonen van microoerganismen.
JPH04207195A (ja) * 1990-11-30 1992-07-29 Shimadzu Corp ウイルスの核酸成分採取方法及びウイルス検査法
FR2674632B1 (fr) * 1991-03-29 1994-07-22 Bertin & Cie Procede et dispositif de detection rapide de micro-organismes indesirables dans un produit du domaine agro-alimentaire ou medico-veterinaire.
GB9107124D0 (en) * 1991-04-05 1991-05-22 Dynal As Chemical process
EP0672176A4 (en) * 1992-01-13 1997-04-09 Abbott Lab A METHOD FOR AMPLIFYING AND DETECTING A TARGETED NUCLEIC ACID SEQUENCE OF HIV-1.
DK39592D0 (da) * 1992-03-25 1992-03-25 Safefood Micro Systsm As Method of detecting microorganisms
GB9208000D0 (en) * 1992-04-10 1992-05-27 Univ London Quantitative viral assay
AU683414B2 (en) * 1992-05-06 1997-11-13 Gen-Probe Incorporated Nucleic acid amplification oligonucleotides and probes to human hepatitis B virus
ES2048652B1 (es) * 1992-06-05 1994-10-01 Inst De Salud Carlos Iii Procedimientos de amplificacion de genoma para la deteccion e identificacion de secuencias genomicas relacionadas.
ES2044784B1 (es) * 1992-06-12 1994-09-01 Inia Procedimiento para la deteccion e identificacion de patogenos virales y subvirales.
JPH07501712A (ja) * 1992-09-29 1995-02-23 シーダーズ−サイナイ・メディカル・センター 微量rnaまはたrnaおよびdna検出用の一段rnaおよび結合一段rnaおよびdnaポリメラーゼ・チェイン・リアクション
WO1994013837A1 (en) * 1992-12-07 1994-06-23 Lionel Resnick Method for detecting a virus
AU6793394A (en) * 1993-06-01 1994-12-20 Ortwin Faff Direct and biochemically functional detection process of retrovirus in biological samples
AU7326494A (en) * 1993-07-13 1995-02-13 Abbott Laboratories Nucleotide sequences and process for amplifying and detection of hepatitis b virus
DE4339352A1 (de) * 1993-11-18 1995-05-24 Univ Ludwigs Albert Verfahren zur Markierung von Zellen, mit diesem Verfahren markierte Zellen, Verwendung des Wildtyp-Adeno-assoziierten Virus zur Markierung von Zellen und Testkits zum Nachweis des Wildtyp-Adeno-assoziierten Virus in Zellen
ES2074961B1 (es) * 1993-12-21 1996-04-01 Inia Procedimiento para analizar estructuralmente el genoma de patogenos virales y subvirales.
ES2078185B1 (es) * 1994-05-06 1996-08-16 Inia Procedimiento para la tipificacion molecular de patogenos virales con genoma rna y de patogenos subvirales mediante sintesis aleatoria de cdna.
TW479072B (en) * 1996-02-02 2002-03-11 Chugai Pharmaceutical Co Ltd Method for quantitative determination of telomerase activity
ES2121698B1 (es) * 1996-12-02 1999-07-01 Inia Procedimiento para la obtencionn de fragmentos amplificados de acido nucleico de particulas virales y subvirales que contienen rna.
US6391622B1 (en) 1997-04-04 2002-05-21 Caliper Technologies Corp. Closed-loop biochemical analyzers
WO1998045481A1 (en) * 1997-04-04 1998-10-15 Caliper Technologies Corporation Closed-loop biochemical analyzers
US6235471B1 (en) 1997-04-04 2001-05-22 Caliper Technologies Corp. Closed-loop biochemical analyzers
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
GB9709728D0 (en) 1997-05-13 1997-07-02 Dynal As Single step method
IT1291913B1 (it) * 1997-05-22 1999-01-21 Angeletti P Ist Richerche Bio Metodo che prevede l'uso di batteriofagi per la rivelazione della presenza di molecole di interesse in campioni biologici
EP1403385A1 (en) * 2002-09-27 2004-03-31 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method for assaying replication of HBV and testing susceptibility to drugs
US20040241662A1 (en) * 2003-05-30 2004-12-02 Robey W. Wade Detecting microbial contamination in grain and related products
KR100829585B1 (ko) * 2006-04-07 2008-05-14 삼성전자주식회사 표적 세포 분리 및 신속한 핵산 분리 방법 및 장치
ES2551892T3 (es) 2006-09-15 2015-11-24 Ottawa Health Research Institute Rhabdovirus oncolítico
US7777877B2 (en) * 2006-10-20 2010-08-17 California Institute Of Technology High efficiency coupling optics for pumping and detection of fluorescence
WO2010088273A1 (en) * 2009-01-27 2010-08-05 Qiagen Gaithersburg Thermophilic helicase dependent amplification technology with endpoint homogenous fluorescent detection
EP2550362B1 (en) 2010-03-25 2017-01-04 Oregon Health&Science University Cmv glycoproteins and recombinant vectors
AU2011258501B2 (en) 2010-05-25 2016-07-07 Qiagen Gaithersburg, Inc. Fast results hybrid capture assay and associated strategically-truncated probes
EP2691530B1 (en) 2011-06-10 2018-03-07 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
US20130189754A1 (en) 2011-09-12 2013-07-25 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
EP2679596B1 (en) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 env glycoprotein variant
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293652A (en) * 1979-05-25 1981-10-06 Cetus Corporation Method for synthesizing DNA sequentially
US4271145A (en) * 1979-10-22 1981-06-02 The Massachusetts General Hospital Process for producing antibodies to hepatitis virus and cell lines therefor
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
FR2537725B1 (fr) * 1982-12-09 1985-07-12 Pasteur Institut Procede de detection immunobacteriologique de germes pathogenes dans des milieux biologiques contamines
GB8331071D0 (en) * 1983-11-22 1983-12-29 Karayiannis P Assay for dna/rna
ES8706823A1 (es) * 1985-03-28 1987-06-16 Cetus Corp Un procedimiento para detectar la presencia o ausencia de al menos una secuencia especifica de acidos nucleicos en una muestra
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
CA1338457C (en) * 1986-08-22 1996-07-16 Henry A. Erlich Purified thermostable enzyme
US5077192A (en) * 1988-10-25 1991-12-31 The General Hospital Corporation Method of detecting antigenic, nucleic acid-containing macromolecular entities

Also Published As

Publication number Publication date
EP0366448A2 (en) 1990-05-02
DE68926991D1 (de) 1996-09-26
US5534406A (en) 1996-07-09
IE76455B1 (en) 1997-10-22
IE893427L (en) 1990-04-25
DE68926991T2 (de) 1997-01-23
US5077192A (en) 1991-12-31
JPH02257899A (ja) 1990-10-18
ATE141651T1 (de) 1996-09-15
CA1340249C (en) 1998-12-15
EP0366448B1 (en) 1996-08-21
EP0366448A3 (en) 1991-10-02

Similar Documents

Publication Publication Date Title
ES2091765T3 (es) Procedimiento de deteccion e identificacion de constituyentes que contienen acido nucleico.
EP0064484A3 (en) Method for fluorescence spectroscopic determination of a biologically active substance
DE3583620D1 (de) Vorrichtung zur photoakustischen detektion von gasen.
PT82882A (pt) Sistema automatico de analise de especimes
DE69434942D1 (de) Mehrzweckreagenzsystem zur schnellen lysierung von vollblutproben
WO1990010709A3 (en) Monoclonal antibodies for metallic cations on small molecules
HU9203445D0 (en) Protein and nucleinic acid samples and immunic essays containing them
ES8706337A1 (es) Un procedimiento para preparar un dispositivo de ensayo para determinar la presencia de leucocitos, esterasa o proteasa en una muestra.
AU6839090A (en) Hepatitis c assay
ATE191792T1 (de) Verfahren zur detektion von hepatitis c
AU7295694A (en) Diagnostic reagents for the detection of antibodies to EBV
BE876053A (fr) Reactif et methode de detection de l'hepatite b
DK603087D0 (da) Immunokemisk metod tilbestemmelse af stabilt glycosyleret haemoglobin
ATE152518T1 (de) Vorrichtung zur zwei-kanälenmessung der fluoreszenz von chlorophyl
EP0202688A3 (en) Method and composition for detecting analyte moieties
DE3880891D1 (de) Vorrichtung und verfahren mit servosteuerung zur aufhebung des ausgangssignals eines faserkreisels.
FR2565967B1 (fr) Procede de preparation d'anhydride trifluoracetique
BR8807616A (pt) Dispositivo de controle de combustivel,sistema de controle de combustivel que emprega o dispositivo e metodo de produzir o dispositivo
FR2611744B1 (fr) Reactif de detection de la catalase par degagement d'oxygene
ES2156858T3 (es) Reactivo de diagnostico para hepatitis c.
ATE76082T1 (de) Reinigungsmethode fuer antikoerper.
FR2622976B1 (fr) Procede et dispositif de localisation non perturbee de missiles
ATE76300T1 (de) Verfahren zur abtrennung und reinigung von t-pa.
AU2562088A (en) Detection of tumor-associated markers in biological fluids
FR2645963B3 (fr) Procede et dispositif pour la determination potentiometrique de la concentration d'ions azoture ou d'acide azothydrique

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 366448

Country of ref document: ES