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ES2089276T5 - Metodo de preparacion del ester metilico de la alfa-l-aspartil-l-fenilalanina. - Google Patents

Metodo de preparacion del ester metilico de la alfa-l-aspartil-l-fenilalanina.

Info

Publication number
ES2089276T5
ES2089276T5 ES92106717T ES92106717T ES2089276T5 ES 2089276 T5 ES2089276 T5 ES 2089276T5 ES 92106717 T ES92106717 T ES 92106717T ES 92106717 T ES92106717 T ES 92106717T ES 2089276 T5 ES2089276 T5 ES 2089276T5
Authority
ES
Spain
Prior art keywords
aspartil
alfa
phenylalanine
preparation
methyl ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92106717T
Other languages
English (en)
Other versions
ES2089276T3 (es
Inventor
Chojiro Higuchi
Ikumi Kitada
Akinori Nagatomo
Katashi Enomoto
Masanobu Ajioka
Akihiro Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Chemicals Inc
Original Assignee
Mitsui Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26435406&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2089276(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mitsui Chemicals Inc filed Critical Mitsui Chemicals Inc
Application granted granted Critical
Publication of ES2089276T3 publication Critical patent/ES2089276T3/es
Publication of ES2089276T5 publication Critical patent/ES2089276T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

ESTER DE METIL DE O NZILOXICARBONIL -O M). LA HIDROGENACION CATALITICA SE CONDUCE EN SUSPENSION ACUOSA QUE CONTIENE EL Z DE INICIACION PUEDE CONTENER HASTA EL 30% DE (BETA) -ISOMERO CON LA CONDICION DE QUE EL PROCESO INCLUYA ADICIONALMENTE LA RECRISTALIZACION DEL O ILTRADO Y EL RECICLADO DEL MATERIAL OBTENIDO MEDIANTE EL FILTRADO PARA SU USO EN UNA SOLUCION ACUOSA DE Z
ES92106717T 1991-04-24 1992-04-18 Metodo de preparacion del ester metilico de la alfa-l-aspartil-l-fenilalanina. Expired - Lifetime ES2089276T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9409191 1991-04-24
JP11610691 1991-05-21

Publications (2)

Publication Number Publication Date
ES2089276T3 ES2089276T3 (es) 1996-10-01
ES2089276T5 true ES2089276T5 (es) 2001-01-16

Family

ID=26435406

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92106717T Expired - Lifetime ES2089276T5 (es) 1991-04-24 1992-04-18 Metodo de preparacion del ester metilico de la alfa-l-aspartil-l-fenilalanina.

Country Status (9)

Country Link
US (1) US5424477A (es)
EP (1) EP0510552B2 (es)
KR (1) KR960005730B1 (es)
AU (1) AU646556B2 (es)
CA (1) CA2066464C (es)
DE (1) DE69211756T3 (es)
ES (1) ES2089276T5 (es)
IE (1) IE921293A1 (es)
TW (1) TW209183B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040226620A1 (en) * 2002-09-26 2004-11-18 Daniel Therriault Microcapillary networks
US7053125B2 (en) * 2002-11-14 2006-05-30 The Board Of Trustees Of The University Of Illinois Controlled dispersion of colloidal suspension by comb polymers
US7141617B2 (en) * 2003-06-17 2006-11-28 The Board Of Trustees Of The University Of Illinois Directed assembly of three-dimensional structures with micron-scale features
US7956102B2 (en) * 2007-04-09 2011-06-07 The Board Of Trustees Of The University Of Illinois Sol-gel inks
US7922939B2 (en) * 2008-10-03 2011-04-12 The Board Of Trustees Of The University Of Illinois Metal nanoparticle inks
US8187500B2 (en) * 2008-10-17 2012-05-29 The Board Of Trustees Of The University Of Illinois Biphasic inks

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH553751A (de) * 1970-05-19 1974-09-13 Stamicarbon Verfahren zur herstellung von aspartylaminosaeure-estern.
BE791544A (fr) * 1971-11-19 1973-05-17 Stamicarbon Preparation d'esters alkyliques de dipeptide
JPS5725538B2 (es) * 1972-01-19 1982-05-29
JPS496305A (es) * 1972-05-12 1974-01-21
JPS5232371B2 (es) * 1972-07-20 1977-08-20
IT1052047B (it) * 1975-12-30 1981-06-20 Pharmedical Sa Lab Procedimento per la sintesi di dipeptidi
JPS5646850A (en) * 1979-09-27 1981-04-28 Ajinomoto Co Inc Method for reductive elimination of protecting group
JPS5725537A (en) * 1980-07-21 1982-02-10 Shin Meiwa Ind Co Ltd Rotary spring device
JPS5740071A (en) * 1980-08-19 1982-03-05 Sugihara Setsukei Jimushiyo Kk Two-tier type cycle rack
IT1197461B (it) * 1983-05-13 1988-11-30 Debi Derivati Biologici Procedimento per la preparazione dell'estere metilico di alfa-l-aspartil-l-fenil-alanina
JPS59227849A (ja) * 1983-06-08 1984-12-21 Ajinomoto Co Inc Ｌ―α―アスパルチル―Ｌ―フェニルアラニンメチルエステル束状晶の晶析分離法
DE3635582A1 (de) * 1986-10-20 1988-04-21 Hoechst Ag Verfahren zur reinigung von n-acyl-aspartam

Also Published As

Publication number Publication date
KR920019815A (ko) 1992-11-20
AU1510192A (en) 1992-11-19
EP0510552B1 (en) 1996-06-26
US5424477A (en) 1995-06-13
TW209183B (es) 1993-07-11
KR960005730B1 (ko) 1996-05-01
DE69211756D1 (de) 1996-08-01
CA2066464A1 (en) 1992-10-25
IE921293A1 (en) 1992-11-04
AU646556B2 (en) 1994-02-24
CA2066464C (en) 1998-04-07
EP0510552B2 (en) 2000-11-15
DE69211756T2 (de) 1997-01-23
EP0510552A1 (en) 1992-10-28
DE69211756T3 (de) 2001-04-19
ES2089276T3 (es) 1996-10-01

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