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ES2083921A1 - Liposomas que contienen hierro (ii) biodisponible y procedimiento para obtenerlos. - Google Patents

Liposomas que contienen hierro (ii) biodisponible y procedimiento para obtenerlos.

Info

Publication number
ES2083921A1
ES2083921A1 ES09401390A ES9401390A ES2083921A1 ES 2083921 A1 ES2083921 A1 ES 2083921A1 ES 09401390 A ES09401390 A ES 09401390A ES 9401390 A ES9401390 A ES 9401390A ES 2083921 A1 ES2083921 A1 ES 2083921A1
Authority
ES
Spain
Prior art keywords
iron
source
liposomes
liposomes containing
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09401390A
Other languages
English (en)
Other versions
ES2083921B1 (es
Inventor
Paoli Tomas De
Alfredo Adolfo Hager
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lipotech SA
Original Assignee
Lipotech SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipotech SA filed Critical Lipotech SA
Publication of ES2083921A1 publication Critical patent/ES2083921A1/es
Application granted granted Critical
Publication of ES2083921B1 publication Critical patent/ES2083921B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/1522—Inorganic additives, e.g. minerals, trace elements; Chlorination or fluoridation of milk; Organic salts or complexes of metals other than natrium or kalium; Calcium enrichment of milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Dairy Products (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

LIPOSOMAS QUE CONTIENEN HIERRO (II) BIODISPONIBLE Y PROCEDIMIENTO PARA OBTENERLOS. LOS LIPOSOMAS COMPRENDEN HIERRO (II) EN SOLUCION ACUOSA MICROENCAPSULADA Y ESTABILIZADA CON AGENTES REDUCTORES INHIBIDORES DE LA OXIDACION A HIERRO (III). ESTOS AGENTES CONSISTEN EN ACIDO ASCORBICO O SUS SALES, EL HIERRO (II) SE PRESENTA COMO SULFATO, LACTATO O CITRATO, LA ENVOLVENTE DE MICROENCAPSULAMIENTO ES UNA MEMBRANA BICAPA DE LECITINA Y LA SOLUCION ACUOSA CONTIENE TAMBIEN OTROS MICROELEMENTOS COMO COBRE, ZINC, COBALTO Y SUS MEZCLAS. EL PROCEDIMIENTO COMPRENDE FORMAR UNA SUSPENSION HOMOGENEA EN AGUA DE FOSFOGLICERIDOS, CONGELAR RAPIDAMENTE LA SUSPENSION A UNA TEMPERATURA DE -10 A -15 C Y DESCONGELARLA LENTAMENTE A TEMPERATURA AMBIENTE, INCORPORAR EN LA SUSPENSION HIERRO (II) EN SOLUCION ACUOSA QUE INCLUYE DICHOS AGENTES REDUCTORES Y MICROELEMENTOS, REPETIR EL CICLO DE CONGELAMIENTO Y DESCONGELAMIENTO, Y SEPARAR LOS LIPOSOMAS FORMADOS. ESTOS SON UTILES EN MEDICINA, NUTRICION DE VEGETALES, INDUSTRIA ALIMENTARIA Y COSMETICA.
ES09401390A 1993-11-09 1994-06-24 Liposomas que contienen hierro (ii) biodisponible y procedimiento para obtenerlos. Expired - Fee Related ES2083921B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AR32654193 1993-11-09

Publications (2)

Publication Number Publication Date
ES2083921A1 true ES2083921A1 (es) 1996-04-16
ES2083921B1 ES2083921B1 (es) 1996-12-01

Family

ID=3478880

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09401390A Expired - Fee Related ES2083921B1 (es) 1993-11-09 1994-06-24 Liposomas que contienen hierro (ii) biodisponible y procedimiento para obtenerlos.

Country Status (15)

Country Link
US (1) US5534268A (es)
JP (1) JP3059341B2 (es)
KR (1) KR0163216B1 (es)
AU (1) AU676384B2 (es)
BR (1) BR9402539A (es)
CA (1) CA2126648C (es)
CO (1) CO4230051A1 (es)
DE (1) DE4421686C2 (es)
ES (1) ES2083921B1 (es)
FR (1) FR2712190B1 (es)
IT (1) IT1269946B (es)
MY (1) MY111380A (es)
NZ (1) NZ264653A (es)
PE (1) PE56594A1 (es)
UY (1) UY23795A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2735658B1 (fr) * 1995-06-21 1997-09-12 Capsulis Encapsulation de composes a usage alimentaire par des tensioactifs
US5707670A (en) * 1996-08-29 1998-01-13 The Procter & Gamble Company Use of bilayer forming emulsifiers in nutritional compositions comprising divalent mineral salts to minimize off-tastes and interactions with other dietary components
CA2402520A1 (en) * 2000-03-13 2001-09-20 Kenneth Beckman Biocidal methods and compositions
US20030124180A1 (en) * 2000-05-02 2003-07-03 Jurgen Ebert Liposomes containing active substances
DE60237162D1 (de) * 2001-10-03 2010-09-09 Celator Pharmaceuticals Inc Liposomenladung mit metallionen
EP1499294B1 (de) * 2002-04-29 2010-08-11 Biotesys Gmbh Polymerisierte peptid-modifizierte lipide als biologische transportsysteme für mikronutrients
WO2004014152A1 (en) * 2002-08-13 2004-02-19 Vitalstate Canada Ltd. Multi-phase delivery system comprising a semi-solid matrix phase
KR20040048749A (ko) * 2002-12-04 2004-06-10 곽해수 비타민 ｃ가 함유된 미세캡슐 및 이를 포함하는철분강화우유
WO2004091305A1 (en) 2003-04-11 2004-10-28 Cargill, Incorporated Pellet systems for preparing beverages
WO2006031857A2 (en) * 2004-09-13 2006-03-23 Gilead Sciences, Inc. Delivering iron to an animal
US9445975B2 (en) 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
JP2010115151A (ja) * 2008-11-13 2010-05-27 Morinaga Milk Ind Co Ltd 調製粉乳の製造方法
JP4927806B2 (ja) * 2008-11-13 2012-05-09 森永乳業株式会社 調製粉乳の製造方法
IT1398765B1 (it) * 2010-03-02 2013-03-18 A V D Reform S R L Integratore alimentare a base di ferro e procedimento per ottenere detto integratore
RU2453149C1 (ru) * 2010-10-19 2012-06-20 Государственное научное учреждение Всероссийский научно-исследовательский институт пищевых ароматизаторов, кислот и красителей Российской академии сельскохозяйственных наук (ГНУ ВНИИПАКК Россельхозакадемии) Способ получения пищевой добавки - лактата железа
CN104041584A (zh) * 2014-05-26 2014-09-17 张宏宇 一种卵磷脂酸奶
IT201700099627A1 (it) * 2017-09-06 2019-03-06 Anna Angela Barba Produzione di vettori nano-liposomiali incapsulanti ferro altamente biodisponibile con tecnica in continuo.
IT201900019775A1 (it) * 2019-10-25 2021-04-25 Health Progress Italia S R L Composizione nutraceutica liposomiale
WO2022034609A1 (en) * 2020-08-11 2022-02-17 Pravin Nalawade Encapsulated carbonyl iron salt compositions and process thereof
CN112516163A (zh) * 2020-12-21 2021-03-19 西安医学院 一种难溶性三价铁纳米脂质体复合物及其制备方法
IT202200020262A1 (it) * 2022-10-03 2024-04-03 Bio Therapic Italia Composizione liposomiale comprendente ferro solfato e suo uso
EP4450065A1 (en) * 2023-04-19 2024-10-23 Bio-Therapic Italia S.r.l. Liposomal composition comprising iron sulphate for use in the treatment and prevention of anaemia in pregnant women and during puerperium

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2481414A (en) * 1945-04-30 1949-09-06 Wisconsin Alumni Res Found Stable fortified milk products and process of preparing same
US4394149A (en) * 1978-02-24 1983-07-19 Szoka Jr Francis C Plant nutriment compositions and method of their application
WO1987000043A1 (en) * 1985-07-05 1987-01-15 The Liposome Company, Inc. Multilamellar liposomes having improved trapping efficiencies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62178521A (ja) * 1986-01-30 1987-08-05 Terumo Corp ヘモグロビン含有リポソ−ム
US5320906A (en) * 1986-12-15 1994-06-14 Vestar, Inc. Delivery vehicles with amphiphile-associated active ingredient
US5139803A (en) * 1989-02-09 1992-08-18 Nabisco, Inc. Method and liposome composition for the stabilization of oxidizable substances

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2481414A (en) * 1945-04-30 1949-09-06 Wisconsin Alumni Res Found Stable fortified milk products and process of preparing same
US4394149A (en) * 1978-02-24 1983-07-19 Szoka Jr Francis C Plant nutriment compositions and method of their application
WO1987000043A1 (en) * 1985-07-05 1987-01-15 The Liposome Company, Inc. Multilamellar liposomes having improved trapping efficiencies

Also Published As

Publication number Publication date
AU676384B2 (en) 1997-03-06
JP3059341B2 (ja) 2000-07-04
BR9402539A (pt) 1995-07-04
CO4230051A1 (es) 1995-10-19
PE56594A1 (es) 1995-01-16
DE4421686C2 (de) 1997-09-04
ITMI941319A0 (it) 1994-06-24
JPH07233078A (ja) 1995-09-05
ES2083921B1 (es) 1996-12-01
ITMI941319A1 (it) 1995-12-24
NZ264653A (en) 1996-06-25
DE4421686A1 (de) 1995-05-11
MY111380A (en) 1999-12-31
CA2126648A1 (en) 1995-05-10
KR0163216B1 (ko) 1998-12-01
AU7768294A (en) 1995-05-18
IT1269946B (it) 1997-04-16
US5534268A (en) 1996-07-09
UY23795A1 (es) 1995-12-22
FR2712190A1 (fr) 1995-05-19
FR2712190B1 (fr) 1997-05-16
CA2126648C (en) 2000-10-10
KR950013500A (ko) 1995-06-15

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