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EP4022094A4 - Biomarker zur diagnose von lungenkrebs - Google Patents

Biomarker zur diagnose von lungenkrebs Download PDF

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Publication number
EP4022094A4
EP4022094A4 EP20857896.3A EP20857896A EP4022094A4 EP 4022094 A4 EP4022094 A4 EP 4022094A4 EP 20857896 A EP20857896 A EP 20857896A EP 4022094 A4 EP4022094 A4 EP 4022094A4
Authority
EP
European Patent Office
Prior art keywords
biomarkers
diagnosis
lung cancers
cancers
lung
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20857896.3A
Other languages
English (en)
French (fr)
Other versions
EP4022094A1 (de
Inventor
Patrick Lilley
III Martin J. KEISER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Liquid Lung Dx
Original Assignee
Liquid Lung Dx
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liquid Lung Dx filed Critical Liquid Lung Dx
Priority to EP23174278.4A priority Critical patent/EP4257982A3/de
Publication of EP4022094A1 publication Critical patent/EP4022094A1/de
Publication of EP4022094A4 publication Critical patent/EP4022094A4/de
Withdrawn legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP20857896.3A 2019-08-26 2020-08-26 Biomarker zur diagnose von lungenkrebs Withdrawn EP4022094A4 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP23174278.4A EP4257982A3 (de) 2019-08-26 2020-08-26 Biomarker zur diagnose von lungenkrebs

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962891943P 2019-08-26 2019-08-26
US201962893088P 2019-08-28 2019-08-28
US201962902943P 2019-09-19 2019-09-19
PCT/US2020/048019 WO2021041556A1 (en) 2019-08-26 2020-08-26 Biomarkers for the diagnosis of lung cancers

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP23174278.4A Division EP4257982A3 (de) 2019-08-26 2020-08-26 Biomarker zur diagnose von lungenkrebs

Publications (2)

Publication Number Publication Date
EP4022094A1 EP4022094A1 (de) 2022-07-06
EP4022094A4 true EP4022094A4 (de) 2022-11-30

Family

ID=74684360

Family Applications (2)

Application Number Title Priority Date Filing Date
EP20857896.3A Withdrawn EP4022094A4 (de) 2019-08-26 2020-08-26 Biomarker zur diagnose von lungenkrebs
EP23174278.4A Pending EP4257982A3 (de) 2019-08-26 2020-08-26 Biomarker zur diagnose von lungenkrebs

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP23174278.4A Pending EP4257982A3 (de) 2019-08-26 2020-08-26 Biomarker zur diagnose von lungenkrebs

Country Status (4)

Country Link
US (2) US11198912B2 (de)
EP (2) EP4022094A4 (de)
JP (1) JP2023504334A (de)
WO (1) WO2021041556A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113252806B (zh) * 2021-03-25 2023-08-29 嘉兴学院 S-腺苷同型半胱氨酸在制备用于诊断或治疗川崎病的产品中的用途
WO2023152568A2 (en) * 2022-02-10 2023-08-17 Oslo Universitetssykehus Hf Compositions and methods for characterizing lung cancer
CN114705863B (zh) * 2022-04-27 2023-06-06 郑州大学第一附属医院 Ssh3蛋白在贲门腺癌预后预测中的应用
CN115040637A (zh) * 2022-05-24 2022-09-13 中南大学湘雅医院 Rcn2重组蛋白在制备预防和/或治疗骨质疏松症以及提升免疫力的药物中的应用
CN114874308B (zh) * 2022-05-26 2023-02-17 苏州大学 一种核素标记的抑制肽及其制备方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2305811A1 (de) * 2005-07-27 2011-04-06 Oncotherapy Science, Inc. Verfahren zur Diagnose von kleinzelligem Lungenkrebs
US20110236903A1 (en) * 2008-12-04 2011-09-29 Mcclelland Michael Materials and methods for determining diagnosis and prognosis of prostate cancer
WO2018213764A1 (en) * 2017-05-19 2018-11-22 Lunella Biotech, Inc. Companion diagnostics for mitochondrial inhibitors
WO2019008414A1 (en) * 2017-07-05 2019-01-10 Datar Rajan GENE EXPRESSION ANALYSIS BASED ON EXOSOMES FOR THE CARE OF CANCER

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070065844A1 (en) * 2005-06-08 2007-03-22 Massachusetts Institute Of Technology Solution-based methods for RNA expression profiling
US20120004116A1 (en) * 2008-12-04 2012-01-05 Ming-Sound Tsao Methods for biomarker identification and biomarker for non-small cell lung cancer
EP2336353A1 (de) * 2009-12-17 2011-06-22 febit holding GmbH miRNA-Fingerabdrücke bei der Diagnose von Krankheiten
US8735074B2 (en) * 2009-08-28 2014-05-27 Asuragen, Inc. MiRNA biomarkers of lung disease
EP2341145A1 (de) * 2009-12-30 2011-07-06 febit holding GmbH miRNA-Fingerabdruck für die Krankheitsdiagnose
CN103237901B (zh) * 2010-03-01 2016-08-03 卡里斯生命科学瑞士控股有限责任公司 用于治疗诊断的生物标志物
EP2744919A4 (de) * 2011-08-19 2015-04-08 Myriad Genetics Inc Gensignaturen für lungenkrebsprognose und therapieauswahl
EP2751292A4 (de) * 2011-09-01 2015-05-20 Allegro Diagnostics Corp Verfahren und zusammensetzungen zum nachweis von krebs auf der basis von mirna-expressionsprofilen
WO2014093872A1 (en) * 2012-12-13 2014-06-19 Baylor Research Institute Blood transcriptional signatures of active pulmonary tuberculosis and sarcoidosis
KR102581812B1 (ko) * 2014-06-18 2023-09-25 국립연구개발법인 고쿠리츠간켄큐센터 폐암의 검출 키트 또는 디바이스 및 검출 방법

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2305811A1 (de) * 2005-07-27 2011-04-06 Oncotherapy Science, Inc. Verfahren zur Diagnose von kleinzelligem Lungenkrebs
US20110236903A1 (en) * 2008-12-04 2011-09-29 Mcclelland Michael Materials and methods for determining diagnosis and prognosis of prostate cancer
WO2018213764A1 (en) * 2017-05-19 2018-11-22 Lunella Biotech, Inc. Companion diagnostics for mitochondrial inhibitors
WO2019008414A1 (en) * 2017-07-05 2019-01-10 Datar Rajan GENE EXPRESSION ANALYSIS BASED ON EXOSOMES FOR THE CARE OF CANCER

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SOTGIA FEDERICA ET AL: "Mitochondrial markers predict survival and progression in non-small cell lung cancer (NSCLC) patients: Use as companion diagnostics", ONCOTARGET, vol. 8, no. 40, 15 September 2017 (2017-09-15), pages 68095 - 68107, XP055967436, DOI: 10.18632/oncotarget.19677 *

Also Published As

Publication number Publication date
US20220106645A1 (en) 2022-04-07
US20210102261A1 (en) 2021-04-08
EP4257982A2 (de) 2023-10-11
JP2023504334A (ja) 2023-02-03
WO2021041556A1 (en) 2021-03-04
EP4022094A1 (de) 2022-07-06
US11198912B2 (en) 2021-12-14
EP4257982A3 (de) 2024-03-06

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