EP3355864A4 - Composition for reducing the frequency of urination, method of making and use thereof - Google Patents

Composition for reducing the frequency of urination, method of making and use thereof Download PDF

Info

Publication number: EP3355864A4
Authority: EP; European Patent Office
Prior art keywords: urination; frequency; reducing; composition; making
Prior art date: 2015-09-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP16852272.0A

Other languages

German (de)

French (fr)

Other versions

EP3355864A1 (en

Inventor

David A. Dill

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wellesley Pharmaceuticals LLC

Original Assignee

Wellesley Pharmaceuticals LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-09-30

Filing date

2016-08-26

Publication date

2019-05-22

2015-09-30 Priority claimed from US14/870,473 external-priority patent/US20160015694A1/en

2016-08-26 Application filed by Wellesley Pharmaceuticals LLC filed Critical Wellesley Pharmaceuticals LLC

2018-08-08 Publication of EP3355864A1 publication Critical patent/EP3355864A1/en

2019-05-22 Publication of EP3355864A4 publication Critical patent/EP3355864A4/en

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

EP16852272.0A 2015-09-30 2016-08-26 Composition for reducing the frequency of urination, method of making and use thereof Withdrawn EP3355864A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US14/870,473 US20160015694A1 (en)	2013-03-13	2015-09-30	Composition for reducing the frequency of urination, method of making and use thereof
PCT/US2016/049018 WO2017058428A1 (en)	2015-09-30	2016-08-26	Composition for reducing the frequency of urination, method of making and use thereof

Publications (2)

Publication Number	Publication Date
EP3355864A1 EP3355864A1 (en)	2018-08-08
EP3355864A4 true EP3355864A4 (en)	2019-05-22

Family

ID=58427764

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP16852272.0A Withdrawn EP3355864A4 (en)	2015-09-30	2016-08-26	Composition for reducing the frequency of urination, method of making and use thereof

Country Status (7)

Country	Link
EP (1)	EP3355864A4 (en)
JP (1)	JP2018529711A (en)
KR (1)	KR20180066112A (en)
CN (1)	CN108391420A (en)
AU (1)	AU2016331871A1 (en)
SG (1)	SG11201805530RA (en)
WO (1)	WO2017058428A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX2018007326A (en) *	2015-12-18	2019-03-28	Wellesley Pharmaceuticals Llc	Composition for reducing frequency of urination, method of making and use thereof.
CN112569204A (en) *	2020-12-30	2021-03-30	湖北人福药用辅料股份有限公司	Pullulan polysaccharide and starch plant enteric-coated capsule and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2014018222A1 (en) *	2012-07-27	2014-01-30	Wellesley Pharmaceuticals, Llc	Pharmaceutical formulation for reducing frequency of urination and method of use thereof
WO2014079922A1 (en) *	2012-11-21	2014-05-30	Ferring B.V.	Composition for immediate and extended release
US20140178441A1 (en) *	2010-07-08	2014-06-26	Wellesley Pharmaceuticals, Llc	Pharmaceutical formulation for reducing frequency of urination and method of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20090317465A1 (en) *	2008-06-16	2009-12-24	Appian Labs, Llc	Composition and method of preparation of release systems for constant (zero-order) release of active agents
SG11201500408VA (en) *	2012-03-19	2015-03-30	Wellesley Pharmaceuticals Llc	Extended-release formulation for reducing the frequency of urination and method of use thereof

2016
- 2016-08-26 EP EP16852272.0A patent/EP3355864A4/en not_active Withdrawn
- 2016-08-26 AU AU2016331871A patent/AU2016331871A1/en not_active Abandoned
- 2016-08-26 SG SG11201805530RA patent/SG11201805530RA/en unknown
- 2016-08-26 JP JP2018516070A patent/JP2018529711A/en active Pending
- 2016-08-26 CN CN201680069684.8A patent/CN108391420A/en active Pending
- 2016-08-26 KR KR1020187011981A patent/KR20180066112A/en unknown
- 2016-08-26 WO PCT/US2016/049018 patent/WO2017058428A1/en active Application Filing

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20140178441A1 (en) *	2010-07-08	2014-06-26	Wellesley Pharmaceuticals, Llc	Pharmaceutical formulation for reducing frequency of urination and method of use thereof
WO2014018222A1 (en) *	2012-07-27	2014-01-30	Wellesley Pharmaceuticals, Llc	Pharmaceutical formulation for reducing frequency of urination and method of use thereof
WO2014079922A1 (en) *	2012-11-21	2014-05-30	Ferring B.V.	Composition for immediate and extended release

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2017058428A1 *

Also Published As

Publication number	Publication date
KR20180066112A (en)	2018-06-18
EP3355864A1 (en)	2018-08-08
JP2018529711A (en)	2018-10-11
CN108391420A (en)	2018-08-10
SG11201805530RA (en)	2018-07-30
WO2017058428A1 (en)	2017-04-06
AU2016331871A1 (en)	2018-05-17

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Legal Events

Date	Code	Title	Description
2018-07-06	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2018-08-08	17P	Request for examination filed	Effective date: 20180424
2018-08-08	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2018-08-08	AX	Request for extension of the european patent	Extension state: BA ME
2019-01-09	DAV	Request for validation of the european patent (deleted)
2019-01-09	DAX	Request for extension of the european patent (deleted)
2019-05-22	A4	Supplementary search report drawn up and despatched	Effective date: 20190425
2019-05-22	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 31/192 20060101ALI20190417BHEP Ipc: A61K 9/24 20060101ALI20190417BHEP Ipc: A61K 9/16 20060101AFI20190417BHEP Ipc: A61K 9/50 20060101ALI20190417BHEP Ipc: A61K 31/167 20060101ALI20190417BHEP Ipc: A61K 9/20 20060101ALI20190417BHEP Ipc: A61K 9/52 20060101ALI20190417BHEP Ipc: A61K 31/405 20060101ALI20190417BHEP Ipc: A61K 45/06 20060101ALI20190417BHEP Ipc: A61K 31/616 20060101ALI20190417BHEP Ipc: A61K 31/12 20060101ALI20190417BHEP
2020-07-10	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2020-08-12	18D	Application deemed to be withdrawn	Effective date: 20191126