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EP3004067A4 - Fungicidal compositions - Google Patents

Fungicidal compositions

Info

Publication number
EP3004067A4
EP3004067A4 EP14803928.2A EP14803928A EP3004067A4 EP 3004067 A4 EP3004067 A4 EP 3004067A4 EP 14803928 A EP14803928 A EP 14803928A EP 3004067 A4 EP3004067 A4 EP 3004067A4
Authority
EP
European Patent Office
Prior art keywords
fungicidal compositions
fungicidal
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14803928.2A
Other languages
German (de)
French (fr)
Other versions
EP3004067A1 (en
Inventor
William J Hoekstra
Michael R Loso
Gary D Gustafson
Daniel Knueppel
Zachary A Buchan
Michael T Sullenberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mycovia Pharmaceuticals Inc
Original Assignee
Viamet Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viamet Pharmaceuticals Inc filed Critical Viamet Pharmaceuticals Inc
Publication of EP3004067A1 publication Critical patent/EP3004067A1/en
Publication of EP3004067A4 publication Critical patent/EP3004067A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP14803928.2A 2013-05-28 2014-05-28 Fungicidal compositions Withdrawn EP3004067A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361828068P 2013-05-28 2013-05-28
PCT/US2014/039823 WO2014193974A1 (en) 2013-05-28 2014-05-28 Fungicidal compositions

Publications (2)

Publication Number Publication Date
EP3004067A1 EP3004067A1 (en) 2016-04-13
EP3004067A4 true EP3004067A4 (en) 2016-10-12

Family

ID=51989367

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14803928.2A Withdrawn EP3004067A4 (en) 2013-05-28 2014-05-28 Fungicidal compositions

Country Status (6)

Country Link
US (1) US9447073B2 (en)
EP (1) EP3004067A4 (en)
JP (1) JP6387401B2 (en)
CA (1) CA2913914C (en)
HK (1) HK1223093A1 (en)
WO (1) WO2014193974A1 (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9914726B2 (en) * 2014-03-19 2018-03-13 Vps-3, Inc. 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and processes for their preparation
WO2015143166A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. Antifungal compound process
US10196375B2 (en) 2014-03-19 2019-02-05 Mycovia Pharmaceuticals, Inc. Antifungal compound process
JP6572234B2 (en) 2014-03-19 2019-09-04 ヴィアメット ファーマスーティカルズ（エヌシー），インコーポレイテッド Process for the preparation of antifungal compounds
KR20160138013A (en) * 2014-03-19 2016-12-02 비아멧 파마슈티컬즈, 인코포레이티드 Antifungal Compound Process
WO2015143192A1 (en) * 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1h-tetrazol-1-yl)propan-2-ols and processes for their preparation
WO2015143172A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. Antifungal compound process
JP2017514790A (en) 2014-03-19 2017-06-08 ヴィアメット ファーマスーティカルズ，インコーポレイテッド Process for the preparation of antifungal compounds
CA2942972A1 (en) 2014-03-19 2015-09-24 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Antifungal compound process
UA120784C2 (en) * 2015-05-18 2020-02-10 Ваймет Фармасьютікалс (Нк), Інк. Antifungal compounds
EP3349587B1 (en) 2015-09-18 2020-07-22 NQP 1598, Ltd. Antifungal compound process
US20180354928A1 (en) * 2015-11-17 2018-12-13 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
TWI636049B (en) * 2015-11-17 2018-09-21 美商維愛美製藥公司 Methods of making 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile
AR106731A1 (en) * 2015-11-17 2018-02-14 Viamet Pharmaceuticals Inc 4 - ((6- (2- (2,4-DIFLUOROFENIL) -1,1-DIFLUORO-2-HIDROXI-3- (1H-1,2,4-TRIAZOL-1-IL) PROPIL) PIRIDIN-3- IL) OXI) BENZONITRILE AND PROCESS FOR PREPARATION
US20180327359A1 (en) * 2015-11-17 2018-11-15 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-oxoethyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
CN109963841A (en) * 2016-11-18 2019-07-02 美国陶氏益农公司 4- ((6- (2- (2,4 difluorobenzene base) -1,1- two fluoro- 2- hydroxyl -3- (5- sulfydryl -1H-1,2,4- triazol-1-yl) propyl) pyridin-3-yl) oxygroup) benzonitrile and preparation method
WO2018094138A1 (en) * 2016-11-18 2018-05-24 Vps-3, Inc. 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl) propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
WO2018094129A1 (en) * 2016-11-18 2018-05-24 Vps-3, Inc. 4-((6-(2-(2,4-dufluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
US20190284159A1 (en) * 2016-11-18 2019-09-19 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
BR112019009788A2 (en) * 2016-11-18 2019-08-06 Dow Agrosciences Llc 4 - ((6- (2- (2,4-difluorophenyl) -1,1-difluoro-2-hydroxy-3- (5-merc apt-1h-1,2,4-triazol-1-yl) propyl ) pyridin-3-yl) oxy) benzonitrile and preparation processes
WO2018094139A1 (en) * 2016-11-18 2018-05-24 Vps-3, Inc. 4-((6-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3(5-mercapto-1h-1,2,4-triazol-1-yl) propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
CN110023296A (en) * 2016-11-18 2019-07-16 美国陶氏益农公司 4- ((6- (2- (2,4 difluorobenzene base) -1,1- two fluoro- 2- hydroxyl -3- (5- sulfydryl -1H-1,2,4- triazol-1-yl) propyl) pyridin-3-yl) oxygroup) benzonitrile and preparation method
BR112019009801A2 (en) * 2016-11-18 2019-08-06 Dow Agrosciences Llc 4 - ((6- (2- (2,4-difluorophenyl) -1,1-difluoro-2-hydroxy-3- (5-mercapto-1h-1,2,4-triazol-1-yl) propyl) pyridin-3-yl) oxy) benzonitrile and preparation processes
EP3541785A4 (en) 2016-11-18 2020-04-01 Dow Agrosciences Llc 4-((6-bromopyridin-3-yl)oxy)benzonitrile and processes of preparation
CA3044340A1 (en) * 2016-11-22 2018-05-31 Dow Agrosciences Llc Fungicidal compounds and mixtures for fungal control in cereals
CA3044386A1 (en) * 2016-11-22 2018-05-31 Dow Agrosciences Llc Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of phytopathogenic fungi of corn
CN109982565A (en) * 2016-11-22 2019-07-05 美国陶氏益农公司 Fungicidal compounds and mixture for fungus control in cereal
JP2020500201A (en) * 2016-11-22 2020-01-09 ダウ アグロサイエンシィズ エルエルシー Use of difluoro- (2-hydroxypropyl) pyridine compounds as fungicides for controlling phytopathogenic fungi in barley
MA46075B1 (en) * 2016-11-22 2020-05-29 Dow Agrosciences Llc Fungicidal compounds and mixtures for the control of fungi in cereals
EP3544432A4 (en) * 2016-11-22 2020-04-22 Dow AgroSciences LLC Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of leaf spot of sugar beets
CA3044383A1 (en) * 2016-11-22 2018-05-31 Dow Agrosciences Llc Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of phytopathogenic fungi of wheat
US20210282401A1 (en) * 2016-11-22 2021-09-16 Dow Agrosciences Llc Fungicidal compounds and mixtures for fungal control in cereals
EP3544431A4 (en) * 2016-11-22 2020-04-22 Dow AgroSciences LLC Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of phytopathogenic fungi of rice
CN109982566A (en) * 2016-11-22 2019-07-05 美国陶氏益农公司 Fungicidal compounds and mixture for fungus control in cereal
MD3559009T2 (en) 2016-12-22 2021-07-31 Calithera Biosciences Inc Compositions and methods for inhibiting arginase activity
KR102714537B1 (en) 2017-05-26 2024-10-11 엘티디 "발렌타-인텔렉트" Novel glutaminyl cyclase inhibitors and the use thereof in treatment of various diseases
RU2697580C1 (en) 2018-08-22 2019-08-15 Общество с ограниченной ответственностью "ЗЕТ Терапевтикс" New zinc complex, its preparation and application for therapy of human and animal diseases
CA3153003C (en) 2018-11-29 2023-10-17 Bayer Cropscience Lp Herbicidal compositions for animal grazelands and methods for applying the same
KR102245533B1 (en) * 2020-11-02 2021-04-28 주식회사 지게차코리아 Vehicle rim and its manufacturing method
KR102474144B1 (en) * 2020-12-07 2022-12-05 주식회사 모토모 Obd hub device with improved convenience

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012177603A2 (en) * 2011-06-19 2012-12-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
WO2012177635A1 (en) * 2011-06-19 2012-12-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8819308D0 (en) 1988-08-13 1988-09-14 Pfizer Ltd Triazole antifungal agents
WO2011082245A2 (en) * 2009-12-31 2011-07-07 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
US8940735B2 (en) 2011-06-23 2015-01-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012177603A2 (en) * 2011-06-19 2012-12-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
WO2012177635A1 (en) * 2011-06-19 2012-12-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2014193974A1 *

Also Published As

Publication number Publication date
HK1223093A1 (en) 2017-07-21
JP2016527191A (en) 2016-09-08
US20160102072A1 (en) 2016-04-14
US9447073B2 (en) 2016-09-20
CA2913914A1 (en) 2014-12-04
EP3004067A1 (en) 2016-04-13
CA2913914C (en) 2018-03-20
JP6387401B2 (en) 2018-09-05
WO2014193974A1 (en) 2014-12-04

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