EP2976044A4 - COMPOSITIONS AND METHODS FOR PROMOTING REGENERATION OF DENTAL TISSUE - Google Patents

COMPOSITIONS AND METHODS FOR PROMOTING REGENERATION OF DENTAL TISSUE

Info

Publication number: EP2976044A4
Authority: EP; European Patent Office
Prior art keywords: compositions; methods; dental tissue; promoting regeneration; regeneration
Prior art date: 2013-03-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP14771102.2A

Other languages

German (de)

French (fr)

Other versions

EP2976044A1 (en

Inventor

Jeremy J Mao

Ying Zheng

Guoming Sun

Songlin Wang

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Columbia University in the City of New York

Original Assignee

Columbia University in the City of New York

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-03-21

Filing date

2014-03-21

Publication date

2016-11-23

2014-03-21 Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York

2016-01-27 Publication of EP2976044A1 publication Critical patent/EP2976044A1/en

2016-11-23 Publication of EP2976044A4 publication Critical patent/EP2976044A4/en

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/04—Alginic acid; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
- C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
- C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Dermatology (AREA)
Public Health (AREA)
Epidemiology (AREA)
Transplantation (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Oral & Maxillofacial Surgery (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Polymers & Plastics (AREA)
Chemical Kinetics & Catalysis (AREA)
Dispersion Chemistry (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Materials For Medical Uses (AREA)
Medicinal Preparation (AREA)

EP14771102.2A 2013-03-21 2014-03-21 COMPOSITIONS AND METHODS FOR PROMOTING REGENERATION OF DENTAL TISSUE Withdrawn EP2976044A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201361804138P	2013-03-21	2013-03-21
US201361831595P	2013-06-05	2013-06-05
PCT/US2014/031512 WO2014153548A1 (en)	2013-03-21	2014-03-21	Compositions and methods for dental tissue regeneration

Publications (2)

Publication Number	Publication Date
EP2976044A1 EP2976044A1 (en)	2016-01-27
EP2976044A4 true EP2976044A4 (en)	2016-11-23

Family

ID=51581532

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP14771102.2A Withdrawn EP2976044A4 (en)	2013-03-21	2014-03-21	COMPOSITIONS AND METHODS FOR PROMOTING REGENERATION OF DENTAL TISSUE

Country Status (3)

Country	Link
EP (1)	EP2976044A4 (en)
CN (1)	CN105228557A (en)
WO (1)	WO2014153548A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2014329547B2 (en)	2013-10-02	2019-05-16	The Board Of Trustees Of The Leland Stanford Junior University	Wnt compositions and methods for purification
AU2015374240B2 (en) *	2014-12-29	2021-11-11	The Board Of Trustees Of The Leland Stanford Junior University	Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production
CN104548212B (en) *	2014-12-31	2018-05-11	新科沃再生医学（苏州）有限公司	One kind promotes dental pulp and the regenerated composition of dentine
KR101772449B1 (en) *	2016-12-27	2017-08-30	주식회사 하이센스바이오	Novel peptide
CN107115561B (en) *	2017-06-19	2019-11-26	中山大学附属口腔医院	A kind of 3D printing timbering material and its preparation method and application
CN109846885A (en) *	2019-04-04	2019-06-07	南通大学附属医院	New uses for rosuvastatin
RU2700933C1 (en) *	2019-05-27	2019-09-24	Артем Иванович Трофименко	Hydrogel for regeneration of tooth pulp and periodontium
CN110897897B (en) *	2019-12-11	2021-03-16	四川大学	A VEGF-loaded chitosan temperature-controlled gel and its preparation method and application
CN113318275B (en) *	2021-08-03	2021-11-02	首都医科大学附属北京口腔医院	Degradable hydrogels for pulp dentin regeneration
CN114107184B (en) *	2021-11-26	2024-10-22	山东中医药大学第二附属医院	Application of siRNA in osteogenic differentiation of dental pulp stem cells
CN114306717B (en) *	2021-11-30	2022-07-26	中国科学院南海海洋研究所	Marine biomedical material for repairing skin wounds and preparation method and application thereof
CN114558171B (en) *	2022-04-01	2022-10-14	四川大学	A kind of preparation method of mineral matrix gel for tooth/bone hard tissue repair and regeneration
CN115137878B (en) *	2022-06-24	2023-12-19	成都世联康健生物科技有限公司	Application of BMP7 cytokine in preparation of injection for promoting endogenous dental pulp regeneration
CN115074324B (en) *	2022-08-23	2022-11-18	首都医科大学	Wnt3a-Wnt10a biological root complex and preparation method thereof
CN115161272A (en) *	2022-08-23	2022-10-11	首都医科大学	A method for promoting odontogenic differentiation of mesenchymal stem cells using Wnt10a and its application
CN117379598B (en) *	2023-07-27	2024-03-22	天津医科大学口腔医院	Polymer hydrogel and preparation method and application thereof
CN117797317A (en) *	2024-02-29	2024-04-02	四川大学	Preparation method of peptide microsphere-chitosan composite material and its products and applications

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2010148229A1 (en) *	2009-06-17	2010-12-23	The Trustees Of Columbia University In The City Of New York	Tooth scaffolds
WO2012011610A1 (en) *	2010-07-21	2012-01-26	Kyoto University	Method for inducing differentiation of human pluripotent stem cell into intermediate mesoderm cell

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2211752A4 (en) *	2007-10-25	2013-10-02	Univ Columbia	BIOPULPA
US8809272B2 (en) *	2010-09-09	2014-08-19	The Board Of Trustees Of The Leland Stanford Junior University	Use of liposomal Wnt composition to enhance osseointegration
WO2012045097A1 (en) *	2010-10-01	2012-04-05	The Trustees Of Columbia University In The City Of New York	Production of dentin, cementum and enamel by cells

2014
- 2014-03-21 EP EP14771102.2A patent/EP2976044A4/en not_active Withdrawn
- 2014-03-21 CN CN201480028994.6A patent/CN105228557A/en active Pending
- 2014-03-21 WO PCT/US2014/031512 patent/WO2014153548A1/en active Application Filing

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2010148229A1 (en) *	2009-06-17	2010-12-23	The Trustees Of Columbia University In The City Of New York	Tooth scaffolds
WO2012011610A1 (en) *	2010-07-21	2012-01-26	Kyoto University	Method for inducing differentiation of human pluripotent stem cell into intermediate mesoderm cell

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2014153548A1 *

Also Published As

Publication number	Publication date
EP2976044A1 (en)	2016-01-27
CN105228557A (en)	2016-01-06
WO2014153548A1 (en)	2014-09-25

Publication	Publication Date	Title
EP2976044A4 (en)	2016-11-23	COMPOSITIONS AND METHODS FOR PROMOTING REGENERATION OF DENTAL TISSUE
IL273135A (en)	2020-04-30	Tissue scaffold materials for tissue regeneration and methods of making
HRP20190318T1 (en)	2019-04-19	PHARMACEUTICAL OR COSMETIC PREPARATION FOR THE TREATMENT OF ALOPECIA
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HK1220601A1 (en)	2017-05-12	Anesthesia applicator/syringe for dental and other uses and methods of use
HK1219434A1 (en)	2017-04-07	Compositions and therapeutic methods for accelerated plaque regression
IL246269B (en)	2021-10-31	Compositions and methods for treating the accumulation of adipose tissue
EP2555788A4 (en)	2014-01-15	METHODS AND COMPOSITIONS FOR CARDIOPROTECTION AND CARDIAC REGENERATION
PL2718434T3 (en)	2018-08-31	COMPOSITIONS AND METHODS FOR THE TREATMENT OF CARDIOUS DISEASE
IL236823A0 (en)	2015-03-31	Compositions for use in the treatment of bone defects
EP2968478A4 (en)	2016-09-07	COMPOSITIONS AND METHODS FOR THE TREATMENT OF CARBOXYHEMOGLOBINEMIA
EP2968084A4 (en)	2016-08-10	COMPOSITIONS FOR THE TREATMENT OF XEROSTOMY AND THE TREATMENT OF TEETH
EP2919824A4 (en)	2016-07-13	METHOD FOR THE CROSSLINKING OF BIOPROTHERTIC TISSUE USING BIO-ORTHOGONAL BINDING PAIRS
EP2964763A4 (en)	2016-09-07	COMPOSITIONS AND METHODS FOR REDUCING SKIN PIGMENTATION
EP2983643A4 (en)	2016-12-28	METHODS FOR HOST CELL ECOTROPISM AND DENTAL PULP REGENERATION
EP2820036A4 (en)	2016-01-20	SUBSTITUTION TREATMENT FOR DENTAL CARIES
EP2964334A4 (en)	2016-10-12	COMPOSITIONS AND METHODS FOR TREATMENT OF ABIRED HAIR

Legal Events

Date	Code	Title	Description
2015-12-25	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2016-01-27	17P	Request for examination filed	Effective date: 20151020
2016-01-27	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2016-01-27	AX	Request for extension of the european patent	Extension state: BA ME
2016-03-09	RIN1	Information on inventor provided before grant (corrected)	Inventor name: SUN, GUOMING Inventor name: ZHENG, YING Inventor name: WANG, SONGLIN Inventor name: MAO, JEREMY J.
2016-06-29	DAX	Request for extension of the european patent (deleted)
2016-11-23	A4	Supplementary search report drawn up and despatched	Effective date: 20161024
2016-11-23	RIC1	Information provided on ipc code assigned before grant	Ipc: A61L 27/24 20060101ALI20161018BHEP Ipc: A61L 27/54 20060101ALI20161018BHEP Ipc: A61L 27/22 20060101AFI20161018BHEP
2018-05-09	17Q	First examination report despatched	Effective date: 20180406
2019-02-15	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2019-03-20	18D	Application deemed to be withdrawn	Effective date: 20181002