EP2515930A4 - Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cells - Google Patents
Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cellsInfo
- Publication number
- EP2515930A4 EP2515930A4 EP10838658.2A EP10838658A EP2515930A4 EP 2515930 A4 EP2515930 A4 EP 2515930A4 EP 10838658 A EP10838658 A EP 10838658A EP 2515930 A4 EP2515930 A4 EP 2515930A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- tumor cells
- leukocyte cell
- compositions related
- met phosphorylation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/195—Chemokines, e.g. RANTES
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28862709P | 2009-12-21 | 2009-12-21 | |
PCT/CN2010/079993 WO2011076095A1 (en) | 2009-12-21 | 2010-12-20 | Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cells |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2515930A1 EP2515930A1 (en) | 2012-10-31 |
EP2515930A4 true EP2515930A4 (en) | 2013-04-10 |
Family
ID=44194951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10838658.2A Withdrawn EP2515930A4 (en) | 2009-12-21 | 2010-12-20 | Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cells |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2515930A4 (en) |
CN (1) | CN102802658A (en) |
TW (1) | TW201200151A (en) |
WO (1) | WO2011076095A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102559739B (en) * | 2012-01-20 | 2014-06-25 | 宁波大学 | Expressing and purifying method of recombinant human-derived LECT2 protein in Pichia pastoris |
US10114023B2 (en) | 2012-04-18 | 2018-10-30 | Massachusetts Institute Of Technology | Method of enhancing the efficacy of anti-hepatocyte growth factor receptor breast cancer therapy by administering an inhibitor of menaINV |
CN109536493A (en) * | 2013-10-02 | 2019-03-29 | 阿尔尼拉姆医药品有限公司 | For inhibiting the composition and method of LECT2 gene expression |
US10745702B2 (en) | 2015-04-08 | 2020-08-18 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of the LECT2 gene |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2347761A1 (en) * | 2008-09-22 | 2011-07-27 | TTY Biopharm Company Limited | A composition with inhibition activity on pathological angiogenesis |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
US5645829A (en) | 1993-06-18 | 1997-07-08 | Beth Israel Hospital Association | Mesothelial cell gene therapy |
ES2325344B1 (en) * | 2004-11-02 | 2010-06-09 | Univ Madrid Autonoma | MULTIFUNCTIONAL AND MULTIVALENT ANGIOGENESIS INHIBITORS. |
CN1785426A (en) * | 2005-10-27 | 2006-06-14 | 南京大学 | Method of inhibiting neonate tumour blood vessel |
AU2006347740A1 (en) * | 2006-08-31 | 2008-03-06 | Abraxis Bioscience, Llc | Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases |
-
2010
- 2010-12-20 EP EP10838658.2A patent/EP2515930A4/en not_active Withdrawn
- 2010-12-20 WO PCT/CN2010/079993 patent/WO2011076095A1/en active Application Filing
- 2010-12-20 CN CN2010800587330A patent/CN102802658A/en active Pending
- 2010-12-21 TW TW099144950A patent/TW201200151A/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2347761A1 (en) * | 2008-09-22 | 2011-07-27 | TTY Biopharm Company Limited | A composition with inhibition activity on pathological angiogenesis |
Non-Patent Citations (3)
Title |
---|
See also references of WO2011076095A1 * |
UCHIDA T ET AL: "Expression pattern of a newly recognized protein, LECT2, in hepatocellular carcinoma and its premalignant lesion", PATHOLOGY INTERNATIONAL, CARLTON SOUTH, AU, vol. 49, no. 2, 1 February 1999 (1999-02-01), pages 147 - 151, XP009159532, ISSN: 1320-5463, [retrieved on 20020301], DOI: 10.1046/J.1440-1827.1999.00836.X * |
YANG ET AL: "Leukocyte cell-derived chemotaxin 2 (LECT2) gene expression can influence intravasation and metastatic ability of hepatoma cells through in vivo study", AMERICAN ASSOCIATION FOR CANCER RESEARCH. PROCEEDINGS OF THE ANNUAL MEETING, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 50, 1 January 2009 (2009-01-01), XP009167645, ISSN: 0197-016X * |
Also Published As
Publication number | Publication date |
---|---|
TW201200151A (en) | 2012-01-01 |
WO2011076095A8 (en) | 2011-09-29 |
EP2515930A1 (en) | 2012-10-31 |
WO2011076095A1 (en) | 2011-06-30 |
CN102802658A (en) | 2012-11-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL258129A (en) | Compositions and methods for enhancing bioenergetic status in female germ cells | |
IL221396A (en) | Compositions for delivering oligonuleotides to liver cells and methods for manufacturing same | |
GB201213868D0 (en) | Improvements in or relating to methods of manufacture | |
AP3598A (en) | Improvements in or relating to cooling | |
EP2536293A4 (en) | Methods and compositions for use in aquaculture | |
PT2793954T (en) | 18f - fluciclovine compositions in citrate buffers | |
GB201013264D0 (en) | Improvements in or relating to cementitious compositions | |
GB201101327D0 (en) | Improvements in or relating to cementitous compositions | |
IL221504B (en) | Compositions and methods for targeting type 1 interferon producing cells | |
GB201004936D0 (en) | Improvements in and relating to furniture | |
EP2515930A4 (en) | Methods and compositions related to reduced met phosphorylation by leukocyte cell-derived chemotaxin 2 in tumor cells | |
IL222343A0 (en) | Compositions comprising allogeneic th1 cells and uses thereof | |
IL224813B (en) | Compositions comprising th1 killer cells and uses thereof | |
GB201015360D0 (en) | Improvements in relation to table | |
ZA201305342B (en) | Improvements in and relating to compositions | |
GB201009275D0 (en) | Improvements in or relating to compositions | |
GB201200327D0 (en) | Improvements in and relating to living walls | |
GB2491342B (en) | Improvements in or relating to waterproof enclosures | |
GB201006592D0 (en) | Improvements in and relating to nutritional compositions | |
GB201101738D0 (en) | Improvements in and relating to compositions | |
GB201101666D0 (en) | Improvements in and relating to compositions | |
GB201017880D0 (en) | Improvements in or relating to biological exfoliation | |
GB0821361D0 (en) | Use of silane-treated particles in laminates to improve clarity | |
GB201015171D0 (en) | Improvements in or relating to storage | |
GB201005997D0 (en) | Improvements in or relating to storage |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20120622 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20130313 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 35/00 20060101ALI20130307BHEP Ipc: A61K 38/19 20060101AFI20130307BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20131015 |