EP2285778A4 - Nicotinamide derivatives - Google Patents

Nicotinamide derivatives

Info

Publication number: EP2285778A4
Authority: EP; European Patent Office
Prior art keywords: nicotinamide derivatives; nicotinamide; derivatives
Prior art date: 2008-04-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP09733745A

Other languages

German (de)

French (fr)

Other versions

EP2285778A1 (en

Inventor

Andrew Katsifis

Ivan Greguric

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

CRC for Biomedical Imaging Development Ltd

Original Assignee

CRC for Biomedical Imaging Development Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-04-22

Filing date

2009-04-22

Publication date

2011-05-11

2008-04-22 Priority claimed from AU2008901989A external-priority patent/AU2008901989A0/en

2009-04-22 Application filed by CRC for Biomedical Imaging Development Ltd filed Critical CRC for Biomedical Imaging Development Ltd

2011-02-23 Publication of EP2285778A1 publication Critical patent/EP2285778A1/en

2011-05-11 Publication of EP2285778A4 publication Critical patent/EP2285778A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Optics & Photonics (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP09733745A 2008-04-22 2009-04-22 Nicotinamide derivatives Withdrawn EP2285778A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AU2008901989A AU2008901989A0 (en)		2008-04-22	Nicotinamide derivatives
PCT/AU2009/000504 WO2009129573A1 (en)	2008-04-22	2009-04-22	Nicotinamide derivatives

Publications (2)

Publication Number	Publication Date
EP2285778A1 EP2285778A1 (en)	2011-02-23
EP2285778A4 true EP2285778A4 (en)	2011-05-11

Family

ID=41216339

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP09733745A Withdrawn EP2285778A4 (en)	2008-04-22	2009-04-22	Nicotinamide derivatives

Country Status (6)

Country	Link
EP (1)	EP2285778A4 (en)
CN (1)	CN102232067A (en)
AU (1)	AU2009240785A1 (en)
CA (1)	CA2753532A1 (en)
NZ (1)	NZ589360A (en)
WO (1)	WO2009129573A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20120107240A1 (en) *	2010-11-03	2012-05-03	The Board Of Trustees Of The Leland Stanford Junior University	Probes and methods of melanoma imaging
US20150023877A1 (en) *	2013-07-18	2015-01-22	The Board Of Trustees Of The Leland Stanford Junior University	Methods of parkinsons disease diagnosis and monitoring treatment
JP2015193545A (en) *	2014-03-31	2015-11-05	国立大学法人京都大学	2-(3-pyridinyl)-1h-benzimidazole derivative compound, and radioactive pharmaceuticals containing the same
CN107556236B (en) *	2017-08-25	2020-01-21	华中科技大学同济医学院附属协和医院	Isotope-substituted targeted melanoma positron imaging agent and preparation method and application thereof
EP3816156A4 (en) *	2018-06-28	2022-04-27	Industry Foundation of Chonnam National University	Radioactive compound for treatment of melanoma and use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2009095872A2 (en) *	2008-01-31	2009-08-06	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Labelled analogues of halobenzamides as multimodal radiopharmaceuticals and their precursors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2904317A1 (en) *	2006-07-27	2008-02-01	Inst Nat Sante Rech Med	ANALOGUES OF HALOGENOBENZAMIDES BRANDED AS RADIOPHARMACEUTICALS

2009
- 2009-04-22 CN CN2009801237149A patent/CN102232067A/en active Pending
- 2009-04-22 AU AU2009240785A patent/AU2009240785A1/en not_active Abandoned
- 2009-04-22 CA CA2753532A patent/CA2753532A1/en not_active Abandoned
- 2009-04-22 EP EP09733745A patent/EP2285778A4/en not_active Withdrawn
- 2009-04-22 NZ NZ589360A patent/NZ589360A/en not_active IP Right Cessation
- 2009-04-22 WO PCT/AU2009/000504 patent/WO2009129573A1/en active Application Filing

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2009095872A2 (en) *	2008-01-31	2009-08-06	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Labelled analogues of halobenzamides as multimodal radiopharmaceuticals and their precursors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2009129573A1 *

Also Published As

Publication number	Publication date
EP2285778A1 (en)	2011-02-23
NZ589360A (en)	2012-08-31
AU2009240785A1 (en)	2009-10-29
WO2009129573A1 (en)	2009-10-29
CN102232067A (en)	2011-11-02
CA2753532A1 (en)	2009-10-29

Publication	Publication Date	Title
HK1256310A1 (en)	2019-09-20	N-sulphonylpyrrole derivatives
IL210548A0 (en)	2011-03-31	Spiroaminodihydrothiazine derivatives
EP2376494A4 (en)	2012-07-11	Dihydropyrimidopyrimidine derivatives
IL206276A0 (en)	2010-12-30	Pyridine derivatives
ZA201100799B (en)	2011-10-26	Imidazopyridin-2-one derivatives
SG10201506608RA (en)	2015-09-29	3-deazaneplanocin derivatives
ZA201201125B (en)	2014-07-30	Pyridin-4-yl derivatives
ZA201100876B (en)	2011-10-26	Pyrrolopyridinylpyrimidin-2-ylamine derivatives
EP2291078A4 (en)	2011-08-24	Oxazolobenzimidazole derivatives
ZA201102449B (en)	2011-12-28	Morpholinopurine derivatives
HK1148283A1 (en)	2011-09-02	Heterocyclic derivatives
EP2279532A4 (en)	2011-07-27	Oxazolobenzimidazole derivatives
IL210869A0 (en)	2011-04-28	Imidazothiadiazoles derivatives
IL208336A0 (en)	2010-12-30	Pyrisazinone derivatives
ZA201100948B (en)	2012-04-25	Acylaminobenzamide derivatives
IL211290A0 (en)	2011-04-28	New 2-amidothiadiazole derivatives
IL210164A0 (en)	2011-03-31	Thiazolylpiperidine derivatives
ZA201005382B (en)	2011-10-26	Substituted heteroarylamide diazepinopyrimidone derivatives
ZA201005381B (en)	2011-10-26	Substituted heteroarylamide oxazepinopyrimidone derivatives
ZA201105050B (en)	2012-03-28	Quinazolinamide derivatives
IL208548A0 (en)	2010-12-30	2-phenyl-4-cyclopropyl-pyrimidine derivatives
ZA201007615B (en)	2011-08-31	Aminopyridine derivatives
EP2292613A4 (en)	2012-05-09	Dihydroindolinone derivatives
EP2285778A4 (en)	2011-05-11	Nicotinamide derivatives
IL213051A0 (en)	2011-07-31	Difluorophenyldiacylhydrazide derivatives

Legal Events

Date	Code	Title	Description
2011-01-21	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2011-02-23	17P	Request for examination filed	Effective date: 20101122
2011-02-23	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR
2011-02-23	AX	Request for extension of the european patent	Extension state: AL BA RS
2011-05-11	A4	Supplementary search report drawn up and despatched	Effective date: 20110408
2011-07-27	DAX	Request for extension of the european patent (deleted)
2012-04-27	REG	Reference to a national code	Ref country code: HK Ref legal event code: DE Ref document number: 1154582 Country of ref document: HK
2013-04-17	17Q	First examination report despatched	Effective date: 20130318
2013-12-06	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2014-01-08	18D	Application deemed to be withdrawn	Effective date: 20130730
2018-11-16	REG	Reference to a national code	Ref country code: HK Ref legal event code: WD Ref document number: 1154582 Country of ref document: HK