EP1926998A4 - Methods of detection of iron deficiency and hemochromatosis - Google Patents
Methods of detection of iron deficiency and hemochromatosisInfo
- Publication number
- EP1926998A4 EP1926998A4 EP06825086A EP06825086A EP1926998A4 EP 1926998 A4 EP1926998 A4 EP 1926998A4 EP 06825086 A EP06825086 A EP 06825086A EP 06825086 A EP06825086 A EP 06825086A EP 1926998 A4 EP1926998 A4 EP 1926998A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- hemochromatosis
- detection
- methods
- iron deficiency
- deficiency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000018565 Hemochromatosis Diseases 0.000 title 1
- 206010022971 Iron Deficiencies Diseases 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/90—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving iron binding capacity of blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/011—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells with lysing, e.g. of erythrocytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/012—Red blood cells
- G01N2015/014—Reticulocytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/016—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/018—Platelets
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1024—Counting particles by non-optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/103—Particle shape
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71984905P | 2005-09-24 | 2005-09-24 | |
US11/524,682 US7609369B2 (en) | 2005-09-24 | 2006-09-21 | Methods of detection of iron deficiency and hemochromatosis |
PCT/US2006/037087 WO2007035916A2 (en) | 2005-09-24 | 2006-09-22 | Methods of detection of iron deficiency and hemochromatosis |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1926998A2 EP1926998A2 (en) | 2008-06-04 |
EP1926998A4 true EP1926998A4 (en) | 2008-11-12 |
EP1926998B1 EP1926998B1 (en) | 2010-12-29 |
Family
ID=37889627
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06825086A Active EP1926998B1 (en) | 2005-09-24 | 2006-09-22 | Methods of detection of iron deficiency and hemochromatosis |
Country Status (5)
Country | Link |
---|---|
US (2) | US7609369B2 (en) |
EP (1) | EP1926998B1 (en) |
JP (1) | JP4743723B2 (en) |
DE (1) | DE602006019284D1 (en) |
WO (1) | WO2007035916A2 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7361510B2 (en) * | 2006-01-20 | 2008-04-22 | Beckman Coulter, Inc. | Methods of detection of iron deficiency |
US20100120081A1 (en) * | 2008-11-07 | 2010-05-13 | Beckman Coulter, Inc. | High sensitivity parameters for the detection of vitamin b12 and/or folate deficiencies and methods of use |
US9464978B2 (en) | 2009-03-04 | 2016-10-11 | Beckman Coulter, Inc. | Cross-instrument method and system for cell population discrimination |
JP2012524908A (en) * | 2009-04-24 | 2012-10-18 | ベックマン コールター, インコーポレイテッド | How to characterize particles |
US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
CN104169719B (en) | 2011-12-29 | 2017-03-08 | 思迪赛特诊断有限公司 | For detecting the method and system of pathogen in biological sample |
WO2014188405A1 (en) | 2013-05-23 | 2014-11-27 | Parasight Ltd. | Method and system for imaging a cell sample |
IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for preparing a monolayer of cells, particularly suitable for diagnosis |
WO2015029032A1 (en) | 2013-08-26 | 2015-03-05 | Parasight Ltd. | Digital microscopy systems, methods and computer program products |
US10482595B2 (en) | 2014-08-27 | 2019-11-19 | S.D. Sight Diagnostics Ltd. | System and method for calculating focus variation for a digital microscope |
WO2017046799A1 (en) | 2015-09-17 | 2017-03-23 | S.D. Sight Diagnostics Ltd | Methods and apparatus for detecting an entity in a bodily sample |
RU2624383C2 (en) * | 2015-12-14 | 2017-07-03 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО КубГМУ Минздрава России) | Method for diagnostics and rehabilitation of children of school age in iron-defective condition |
US11733150B2 (en) | 2016-03-30 | 2023-08-22 | S.D. Sight Diagnostics Ltd. | Distinguishing between blood sample components |
EP3455626A1 (en) | 2016-05-11 | 2019-03-20 | S.D. Sight Diagnostics Ltd. | Performing optical measurements on a sample |
EP4177593A1 (en) | 2016-05-11 | 2023-05-10 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
CA3081669A1 (en) | 2017-11-14 | 2019-05-23 | S.D. Sight Diagnostics Ltd | Sample carrier for optical measurements |
CN108416767B (en) * | 2018-02-09 | 2021-02-19 | 重庆东渝中能实业有限公司 | Holographic imaging-based method for detecting multiple physiological parameters of red blood cells |
WO2020037248A1 (en) * | 2018-08-17 | 2020-02-20 | The Regents Of The University Of California | Diagnosing hypoadrenocorticism from hematologic and serum chemistry parameters using machine learning algorithm |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001035095A2 (en) * | 1999-11-12 | 2001-05-17 | Rothenberg Barry E | Diagnostic test for hemochromatosis |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2656508A (en) | 1949-08-27 | 1953-10-20 | Wallace H Coulter | Means for counting particles suspended in a fluid |
US3810011A (en) | 1970-05-25 | 1974-05-07 | Coulter Electronics | Apparatus and method for analyzing the particle volume distribution for a plurality of particles of different size in a quantity of liquid |
US4521518A (en) | 1980-06-16 | 1985-06-04 | Coulter Electronics, Inc. | Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes |
US4528274A (en) | 1982-07-06 | 1985-07-09 | Coulter Electronics, Inc. | Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes |
JPS61115188A (en) * | 1984-11-09 | 1986-06-02 | Toa Medical Electronics Co Ltd | Reticular erythrocyte inspecting method |
KR970007077B1 (en) | 1987-03-13 | 1997-05-02 | 코울터 일렉트로닉스 인커퍼레이티드 | Multi-part diefferential analyzing apparatus using light scatter techniques |
JP2667867B2 (en) * | 1988-03-30 | 1997-10-27 | 東亜医用電子株式会社 | Particle analyzer |
WO1991015592A1 (en) * | 1990-04-11 | 1991-10-17 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | A simple, rapid and reliable method for detecting thalassemia |
US5834315A (en) | 1994-12-23 | 1998-11-10 | Coulter Corporation | Cyanide-free reagent and method for hemoglobin determination and leukocyte differentitation |
US5882934A (en) | 1997-01-21 | 1999-03-16 | Coulter International Corp. | Composition and method for hemoglobin and cell analysis |
US5763280A (en) | 1997-01-21 | 1998-06-09 | Coulter International Corp. | Cyanide-free lytic reagent composition and method for hemoglobin and cell analysis |
US6114173A (en) * | 1997-04-03 | 2000-09-05 | Bayer Corporation | Fully automated method and reagent composition therefor for rapid identification and characterization of reticulocytes erythrocytes and platelets in whole blood |
US5935857A (en) | 1997-08-01 | 1999-08-10 | Coulter International Corp. | Blood diluent |
JPH11326315A (en) * | 1998-05-21 | 1999-11-26 | Sysmex Corp | Method for screening beta-thalassemia |
US6228652B1 (en) | 1999-02-16 | 2001-05-08 | Coulter International Corp. | Method and apparatus for analyzing cells in a whole blood sample |
US6268217B1 (en) | 1999-11-12 | 2001-07-31 | James C. Barton | Erythrocyte parameters in hemochromatosis |
US6573102B2 (en) | 2001-07-27 | 2003-06-03 | Coulter International Corp. | Lytic reagent composition for determination of nucleated blood cells |
US7659074B2 (en) * | 2001-09-14 | 2010-02-09 | Roche Diagnostics Corporation | Diagnosis and treatment of disorders of iron metabolism |
US6706526B2 (en) | 2002-01-24 | 2004-03-16 | Coulter International Corp. | Low formaldehyde producing blood diluent |
US7586589B2 (en) * | 2005-09-24 | 2009-09-08 | Beckman Coulter, Inc. | Methods of determination of responsiveness to erythropoietin treatment |
-
2006
- 2006-09-21 US US11/524,682 patent/US7609369B2/en active Active
- 2006-09-22 JP JP2008532438A patent/JP4743723B2/en not_active Expired - Fee Related
- 2006-09-22 WO PCT/US2006/037087 patent/WO2007035916A2/en active Application Filing
- 2006-09-22 DE DE602006019284T patent/DE602006019284D1/en active Active
- 2006-09-22 EP EP06825086A patent/EP1926998B1/en active Active
-
2009
- 2009-08-31 US US12/550,626 patent/US8154713B2/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001035095A2 (en) * | 1999-11-12 | 2001-05-17 | Rothenberg Barry E | Diagnostic test for hemochromatosis |
Non-Patent Citations (2)
Title |
---|
FRANCK SUSANNE ET AL: "Potential utility of Ret-Y in the diagnosis of iron-restricted erythropoiesis.", CLINICAL CHEMISTRY JUL 2004, vol. 50, no. 7, July 2004 (2004-07-01), pages 1240 - 1242, XP002495522, ISSN: 0009-9147 * |
THOMAS CHRISTIAN ET AL: "Biochemical markers and hematologic indices in the diagnosis of functional iron deficiency", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, vol. 48, no. 7, 1 July 2002 (2002-07-01), pages 1066 - 1076, XP002247459, ISSN: 0009-9147 * |
Also Published As
Publication number | Publication date |
---|---|
WO2007035916A3 (en) | 2007-10-11 |
EP1926998A2 (en) | 2008-06-04 |
US20070072300A1 (en) | 2007-03-29 |
JP2009511861A (en) | 2009-03-19 |
WO2007035916A2 (en) | 2007-03-29 |
EP1926998B1 (en) | 2010-12-29 |
US20100003713A1 (en) | 2010-01-07 |
DE602006019284D1 (en) | 2011-02-10 |
JP4743723B2 (en) | 2011-08-10 |
US8154713B2 (en) | 2012-04-10 |
US7609369B2 (en) | 2009-10-27 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: G01N 33/72 20060101ALI20080930BHEP Ipc: G01N 33/80 20060101ALI20080930BHEP Ipc: G01N 33/49 20060101AFI20080930BHEP |
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