EP1128832A4 - Verbindungen, zusammenstellungen und methoden zur phophylaxe und behandlung von viralen infektionen und damit verbundenen erkrankungen - Google Patents
Verbindungen, zusammenstellungen und methoden zur phophylaxe und behandlung von viralen infektionen und damit verbundenen erkrankungenInfo
- Publication number
- EP1128832A4 EP1128832A4 EP99942288A EP99942288A EP1128832A4 EP 1128832 A4 EP1128832 A4 EP 1128832A4 EP 99942288 A EP99942288 A EP 99942288A EP 99942288 A EP99942288 A EP 99942288A EP 1128832 A4 EP1128832 A4 EP 1128832A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- treating
- compounds
- methods
- viral infections
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9747698P | 1998-08-21 | 1998-08-21 | |
| US97476P | 1998-08-21 | ||
| US11321298P | 1998-12-22 | 1998-12-22 | |
| US113212P | 1998-12-22 | ||
| US11932899P | 1999-02-09 | 1999-02-09 | |
| US119328P | 1999-02-09 | ||
| US13558599P | 1999-05-24 | 1999-05-24 | |
| US13558699P | 1999-05-24 | 1999-05-24 | |
| US135586P | 1999-05-24 | ||
| US135585P | 1999-05-24 | ||
| PCT/US1999/018785 WO2000010573A1 (en) | 1998-08-21 | 1999-08-19 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1128832A1 EP1128832A1 (de) | 2001-09-05 |
| EP1128832A4 true EP1128832A4 (de) | 2003-03-05 |
Family
ID=27536838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP99942288A Withdrawn EP1128832A4 (de) | 1998-08-21 | 1999-08-19 | Verbindungen, zusammenstellungen und methoden zur phophylaxe und behandlung von viralen infektionen und damit verbundenen erkrankungen |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1128832A4 (de) |
| JP (1) | JP2002523371A (de) |
| KR (1) | KR20010099623A (de) |
| CN (1) | CN1325309A (de) |
| AU (1) | AU743411B2 (de) |
| BR (1) | BR9913157A (de) |
| CA (1) | CA2341970A1 (de) |
| ID (1) | ID27787A (de) |
| IL (1) | IL141456A0 (de) |
| WO (1) | WO2000010573A1 (de) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200103562T2 (tr) * | 1999-06-10 | 2002-04-22 | Warner-Lambert Company | Amiloid proteini toplanmasını önleme ve amiloid birikintilerini görüntüleme yönteminde kullanım için rodanin türevleri |
| CA2383347A1 (en) | 1999-08-31 | 2001-03-08 | Maxia Pharmaceuticals, Inc. | Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes |
| WO2001077091A2 (en) * | 2000-04-05 | 2001-10-18 | Tularik Inc. | Ns5b hcv polymerase inhibitors |
| US6448281B1 (en) | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| IL154993A0 (en) * | 2000-09-29 | 2003-10-31 | Neurogen Corp | High affinity small molecule c5a receptor modulators |
| PL373912A1 (en) | 2001-03-07 | 2005-09-19 | Incyte San Diego, Inc. | Heterocyclic derivatives for the treatment of cancer and other proliferative diseases |
| US7265139B2 (en) | 2001-03-08 | 2007-09-04 | Incyte San Diego Inc. | RXR activating molecules |
| GB2376944A (en) * | 2001-05-18 | 2002-12-31 | Pantherix Ltd | Polycyclic heterocyclic compounds and their therapeutic use |
| WO2003007945A1 (en) | 2001-07-20 | 2003-01-30 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| EP2335700A1 (de) | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C Virus Polymerase Inhibitoren mit heterobicylischer Struktur |
| EP1429759A4 (de) | 2001-09-26 | 2004-12-15 | Bristol Myers Squibb Co | Verbindungen zur behandlung des hepatitus c virus |
| JP2005513026A (ja) * | 2001-11-15 | 2005-05-12 | インサイト サン ディエゴ インコーポレイテッド | 高コレステロール血症、異脂肪血症および他の代謝障害；癌、および他の疾患を治療するｎ−置換複素環 |
| US7196108B2 (en) | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
| US7102000B2 (en) | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
| GB2387172A (en) * | 2002-03-28 | 2003-10-08 | Pantherix Ltd | [(Aryl-/arylthio-)aryl]methylene substituted azole & azine derivatives and their therapeutic use as antibacterials |
| JP2005535593A (ja) * | 2002-05-17 | 2005-11-24 | キューエルティー インコーポレーティッド | チアゾリジンジチオン誘導体の使用方法 |
| ATE503764T1 (de) | 2002-05-20 | 2011-04-15 | Bristol Myers Squibb Co | Inhibitoren des hepatitis-c-virus |
| PL213029B1 (pl) | 2002-05-20 | 2012-12-31 | Bristol Myers Squibb Co | Podstawiona pochodna cykloalkilowa, zawierajaca ja kompozycja oraz ich zastosowanie |
| EP1506000B9 (de) | 2002-05-20 | 2011-08-31 | Bristol-Myers Squibb Company | Heterocyclische sulfonamid-hepatitis-c-virus-hemmer |
| MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
| MXPA05000020A (es) | 2002-07-01 | 2005-12-05 | Pharmacia & Upjohn Co Llc | Inhibidores de polimerasa ns5b de la infeccion del virus de la hepatitis c (hcv). |
| MXPA05000256A (es) | 2002-07-01 | 2005-07-15 | Upjohn Co | Inhibidores de polimerasa ns5b del vhc. |
| FR2845000B1 (fr) | 2002-09-27 | 2005-05-27 | Oreal | Utilisation d'un compose heterocyclique ou de l'un de ses sels pour stimuler ou induire la pousse des cheveux et/ou freiner leur chute |
| EA009847B1 (ru) * | 2002-09-30 | 2008-04-28 | Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния | Ингибиторы белка-регулятора трансмембранной проводимости при муковисцидозе и их применение |
| US7235573B2 (en) | 2002-09-30 | 2007-06-26 | The Regents Of The University Of California | Methods of treating secretory diarrhea using cystic fibrosis transmembrane conductance regulator protein inhibitors |
| WO2004043955A1 (en) * | 2002-11-13 | 2004-05-27 | Rigel Pharmaceuticals, Inc. | Rhodanine derivatives and pharmaceutical compositions containing them |
| ES2320771T3 (es) | 2003-04-16 | 2009-05-28 | Bristol-Myers Squibb Company | Inhibidores peptidicos de isoquinolina macrociclicos del virus de la hepatitis c. |
| DE602004025708D1 (de) | 2003-07-11 | 2010-04-08 | Proteologics Inc | Ubiquitin-ligase-hemmer und verwandte verfahren |
| FR2858324A1 (fr) * | 2003-07-30 | 2005-02-04 | Centre Nat Rech Scient | Nouveaux composes antibiotiques, compositions pharmaceutiques les contenant et leurs utilisations |
| US7112601B2 (en) | 2003-09-11 | 2006-09-26 | Bristol-Myers Squibb Company | Cycloalkyl heterocycles for treating hepatitis C virus |
| US7566732B2 (en) | 2003-10-28 | 2009-07-28 | Rigel Pharmaceuticals, Inc. | Rhodanine compositions for use as antiviral agents |
| US7026339B2 (en) | 2003-11-07 | 2006-04-11 | Fan Yang | Inhibitors of HCV NS5B polymerase |
| US7132504B2 (en) | 2003-11-12 | 2006-11-07 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7309708B2 (en) | 2003-11-20 | 2007-12-18 | Birstol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7135462B2 (en) | 2003-11-20 | 2006-11-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| CN101648944A (zh) | 2004-02-20 | 2010-02-17 | 贝林格尔.英格海姆国际有限公司 | 病毒聚合酶抑制剂 |
| RS50815B (sr) | 2004-02-24 | 2010-08-31 | Japan Tobacco Inc. | Kondenzovana heterotetraciklična jedinjenja i njihova upotreba kao inhibitora hcv polimeraza |
| US20070049593A1 (en) | 2004-02-24 | 2007-03-01 | Japan Tobacco Inc. | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor |
| US7659263B2 (en) | 2004-11-12 | 2010-02-09 | Japan Tobacco Inc. | Thienopyrrole compound and use thereof as HCV polymerase inhibitor |
| JP2008540370A (ja) | 2005-05-04 | 2008-11-20 | エフ．ホフマン−ラ ロシュ アーゲー | ヘテロ環式抗ウイルス化合物 |
| WO2006138118A2 (en) * | 2005-06-15 | 2006-12-28 | New York Blood Center | Anti-viral compositions comprising heterocyclic substituted phenyl furans and related compounds |
| US8017612B2 (en) | 2006-04-18 | 2011-09-13 | Japan Tobacco Inc. | Piperazine compound and use thereof as a HCV polymerase inhibitor |
| US8609668B2 (en) * | 2006-05-04 | 2013-12-17 | Philadelphia Health & Education Corporation | Substituted triazolo[1,5-A]pyrimidines as antiviral agents |
| ES2358853T3 (es) | 2006-10-10 | 2011-05-16 | Medivir Ab | Inhibidor nucleosídico de vhc. |
| WO2008082537A2 (en) * | 2006-12-19 | 2008-07-10 | The General Hospital Corporation | Compounds for modulating integrin cd11b/cd18 |
| JP5465666B2 (ja) | 2007-06-29 | 2014-04-09 | ギリアード サイエンシーズ， インコーポレイテッド | 抗ウイルス化合物 |
| KR20100038417A (ko) | 2007-06-29 | 2010-04-14 | 길리애드 사이언시즈, 인코포레이티드 | 항바이러스 화합물 |
| JP2011502998A (ja) * | 2007-11-01 | 2011-01-27 | ザ ユーエイビー リサーチ ファウンデイション | ウイルス感染の治療および予防 |
| WO2009105140A2 (en) | 2007-12-11 | 2009-08-27 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties |
| US7947717B2 (en) | 2008-07-18 | 2011-05-24 | Burnham Institute For Medical Research | Inhibitors of lethal factor protease |
| PE20120207A1 (es) | 2008-12-03 | 2012-03-31 | Presidio Pharmaceuticals Inc | Derivados de naftaleno, como inhibidores de hcv ns5a |
| EA024853B1 (ru) | 2008-12-03 | 2016-10-31 | Пресидио Фармасьютикалс, Инк. | Ингибиторы ns5a вгс |
| CA2755658A1 (en) | 2009-03-27 | 2010-09-30 | Presidio Pharmaceuticals, Inc. | Fused ring inhibitors of hepatitis c |
| NZ599373A (en) | 2009-11-14 | 2013-04-26 | Hoffmann La Roche | Biomarkers for predicting rapid response to hcv treatment |
| SG181104A1 (en) | 2009-12-02 | 2012-07-30 | Hoffmann La Roche | Biomarkers for predicting sustained response to hcv treatment |
| US20130065897A1 (en) * | 2009-12-23 | 2013-03-14 | Peter Maccallum Cancer Institute | Compounds, preparation and uses thereof |
| US8877707B2 (en) | 2010-05-24 | 2014-11-04 | Presidio Pharmaceuticals, Inc. | Inhibitors of HCV NS5A |
| KR101159000B1 (ko) * | 2010-06-18 | 2012-06-21 | (주) 에빅스젠 | 신규한 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 ａｉｄｓ 예방 또는 치료용 약학 조성물 |
| US9023876B2 (en) | 2010-07-08 | 2015-05-05 | Adhaere Pharmaceuticals, Inc. | Compounds and methods for regulating integrins |
| US9255088B2 (en) | 2010-08-11 | 2016-02-09 | The Regents Of The University Of California | Premature-termination-codons readthrough compounds |
| WO2012123298A1 (en) | 2011-03-11 | 2012-09-20 | F. Hoffmann-La Roche Ag | Antiviral compounds |
| US20120328565A1 (en) | 2011-06-24 | 2012-12-27 | Brinkman John A | Antiviral compounds |
| RU2014117587A (ru) | 2011-10-10 | 2015-11-20 | Ф. Хоффманн-Ля Рош Аг | Противовирусные соединения |
| KR20140104030A (ko) | 2011-12-16 | 2014-08-27 | 에프. 호프만-라 로슈 아게 | Hcv ns5a의 억제제 |
| PL2794629T3 (pl) | 2011-12-20 | 2018-02-28 | Riboscience Llc | 2',4'-difluoro-2'-metylo-podstawione pochodne nukleozydowe jako inhibitory replikacji rna hcv |
| BR112014015066A2 (pt) | 2011-12-20 | 2017-06-13 | Hoffmann La Roche | derivados de nucleosídeos 4'azido-3'-flúor substituídos como inibidores de replicação do rna de hcv |
| CA2857262A1 (en) | 2012-02-24 | 2013-08-29 | F. Hoffmann-La Roche Ag | Antiviral compounds |
| EP2828249B1 (de) | 2012-03-23 | 2018-10-10 | The Regents of The University of California | Verbindungen für durchlesen von codons mit vorzeitigem abschluss |
| CA2882853C (en) | 2012-04-20 | 2021-11-23 | Vineet Gupta | Compounds and methods for regulating integrins |
| US20140010783A1 (en) | 2012-07-06 | 2014-01-09 | Hoffmann-La Roche Inc. | Antiviral compounds |
| CA2892589A1 (en) | 2013-01-23 | 2014-07-31 | F. Hoffmann-La Roche Ag | Antiviral triazole derivatives |
| US9428469B2 (en) | 2013-03-05 | 2016-08-30 | Hoffmann-La Roche | Antiviral compounds |
| RU2534613C2 (ru) | 2013-03-22 | 2014-11-27 | Александр Васильевич Иващенко | Алкил 2-{ [(2r,3s,5r)-5-(4-амино-2-оксо-2н-пиримидин-1-ил)- -гидрокси-тетрагидро-фуран-2-илметокси]-фенокси-фосфориламино} -пропионаты, нуклеозидные ингибиторы рнк-полимеразы hcv ns5b, способы их получения и применения |
| US20180200280A1 (en) | 2013-05-16 | 2018-07-19 | Riboscience Llc | 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication |
| MX2015015781A (es) | 2013-05-16 | 2016-06-02 | Riboscience Llc | Derivados de nucleósido 4'-azido, 3'-deoxi-3'-fluoro sustituido. |
| US9895442B2 (en) | 2013-05-16 | 2018-02-20 | Riboscience Llc | 4′-fluoro-2′-methyl substituted nucleoside derivatives as inhibitors of HCV RNA replication |
| CA3075645A1 (en) | 2017-09-21 | 2019-03-28 | Riboscience Llc | 4'-fluoro-2'-methyl substituted nucleoside derivatives as inhibitors of hcv rna replication |
| KR101893988B1 (ko) | 2018-05-16 | 2018-08-31 | (주)에빅스젠 | 로다닌 유도체를 함유하는 aids 예방 또는 치료용 약학 조성물 |
| WO2023161427A1 (en) | 2022-02-24 | 2023-08-31 | Eisbach Bio Gmbh | Viral combination therapy |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993021934A1 (en) * | 1992-05-01 | 1993-11-11 | Commonwealth Scientific And Industrial Research Organisation | Heteropolytungstates in the treatment of flavivirus infections |
| WO1998020013A1 (de) * | 1996-11-07 | 1998-05-14 | Andreas Johannes Kesel | Neue knoevenagel-kondensationsprodukte, verfahren zu deren herstellung und verwendung |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909467A (en) * | 1958-07-09 | 1959-10-20 | Us Vitamin Pharm Corp | 3-(d-alpha-methylphenethyl)-5-methyl-1, 3-oxazolidine-2, 4-dione |
| US3888984A (en) * | 1972-03-13 | 1975-06-10 | Lilly Industries Ltd | Oxazole and imidazole derivatives as antifungal agents |
| AU6610081A (en) * | 1980-01-24 | 1981-07-30 | Senju Pharmaceutical Co., Ltd. | Thiazolidine derivatives |
| US4367234A (en) * | 1980-07-28 | 1983-01-04 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
| CA2153553A1 (en) * | 1994-07-13 | 1996-01-14 | Hidekazu Suzuki | Stable lipid emulsion |
| US5834466A (en) * | 1994-12-22 | 1998-11-10 | The Regents Of The University Of California | Method for protecting of heart by limiting metabolic and ionic abnormalities developed during ischemia, following ischemia or resulting from ischemia |
-
1999
- 1999-08-19 EP EP99942288A patent/EP1128832A4/de not_active Withdrawn
- 1999-08-19 AU AU55702/99A patent/AU743411B2/en not_active Ceased
- 1999-08-19 JP JP2000565894A patent/JP2002523371A/ja active Pending
- 1999-08-19 CA CA002341970A patent/CA2341970A1/en not_active Abandoned
- 1999-08-19 ID IDW20010428A patent/ID27787A/id unknown
- 1999-08-19 CN CN99812282A patent/CN1325309A/zh active Pending
- 1999-08-19 KR KR1020017002117A patent/KR20010099623A/ko not_active Application Discontinuation
- 1999-08-19 WO PCT/US1999/018785 patent/WO2000010573A1/en not_active Application Discontinuation
- 1999-08-19 BR BR9913157-9A patent/BR9913157A/pt not_active Application Discontinuation
- 1999-08-19 IL IL14145699A patent/IL141456A0/xx unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993021934A1 (en) * | 1992-05-01 | 1993-11-11 | Commonwealth Scientific And Industrial Research Organisation | Heteropolytungstates in the treatment of flavivirus infections |
| WO1998020013A1 (de) * | 1996-11-07 | 1998-05-14 | Andreas Johannes Kesel | Neue knoevenagel-kondensationsprodukte, verfahren zu deren herstellung und verwendung |
Non-Patent Citations (1)
| Title |
|---|
| See also references of WO0010573A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU743411B2 (en) | 2002-01-24 |
| JP2002523371A (ja) | 2002-07-30 |
| CN1325309A (zh) | 2001-12-05 |
| AU5570299A (en) | 2000-03-14 |
| WO2000010573A1 (en) | 2000-03-02 |
| IL141456A0 (en) | 2002-03-10 |
| BR9913157A (pt) | 2001-05-15 |
| EP1128832A1 (de) | 2001-09-05 |
| CA2341970A1 (en) | 2000-03-02 |
| ID27787A (id) | 2001-04-26 |
| KR20010099623A (ko) | 2001-11-09 |
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