EP1166076A4 - Snp detection - Google Patents
Snp detectionInfo
- Publication number
- EP1166076A4 EP1166076A4 EP00914711A EP00914711A EP1166076A4 EP 1166076 A4 EP1166076 A4 EP 1166076A4 EP 00914711 A EP00914711 A EP 00914711A EP 00914711 A EP00914711 A EP 00914711A EP 1166076 A4 EP1166076 A4 EP 1166076A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- snp detection
- snp
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US259898 | 1988-10-19 | ||
US09/259,898 US6410231B1 (en) | 1999-02-26 | 1999-02-26 | SNP detection |
PCT/US2000/004876 WO2000050869A2 (en) | 1999-02-26 | 2000-02-24 | Snp detection |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1166076A2 EP1166076A2 (en) | 2002-01-02 |
EP1166076A4 true EP1166076A4 (en) | 2004-10-27 |
Family
ID=22986903
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00914711A Withdrawn EP1166076A4 (en) | 1999-02-26 | 2000-02-24 | Snp detection |
Country Status (6)
Country | Link |
---|---|
US (2) | US6410231B1 (en) |
EP (1) | EP1166076A4 (en) |
JP (1) | JP2002537780A (en) |
AU (1) | AU755398B2 (en) |
CA (1) | CA2362619A1 (en) |
WO (1) | WO2000050869A2 (en) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7582421B2 (en) * | 1993-11-01 | 2009-09-01 | Nanogen, Inc. | Methods for determination of single nucleic acid polymorphisms using a bioelectronic microchip |
US6596487B2 (en) | 2000-03-10 | 2003-07-22 | Ana-Gen Technologies, Inc. | Mutation detection using denaturing gradients |
US6844154B2 (en) * | 2000-04-04 | 2005-01-18 | Polygenyx, Inc. | High throughput methods for haplotyping |
US6380377B1 (en) * | 2000-07-14 | 2002-04-30 | Applied Gene Technologies, Inc. | Nucleic acid hairpin probes and uses thereof |
ATE404688T1 (en) * | 2000-09-06 | 2008-08-15 | Timothy A Hodge | METHOD FOR SCREENING GENOMIC DNA, PARTICULARLY IN TRANSGENIC AND TARGETED MUtagenesis |
US6905816B2 (en) | 2000-11-27 | 2005-06-14 | Intelligent Medical Devices, Inc. | Clinically intelligent diagnostic devices and methods |
GB0105330D0 (en) | 2001-03-02 | 2001-04-18 | Renovo Ltd | Genetic testing |
US6979541B1 (en) * | 2001-07-26 | 2005-12-27 | University Of Utah Research Foundation | Methods for identifying chromosomal aneuploidy |
WO2003018835A2 (en) * | 2001-08-23 | 2003-03-06 | Hvidovre Hospital | Method for rapid detection of haplotypes |
KR100437625B1 (en) * | 2001-09-17 | 2004-06-30 | 주식회사 마이진 | Method for Dectecting the Single Nucleotide Polymorphism by Zip-Code Oligonucleotide Chip and Detection kit |
CN1310652C (en) | 2001-11-29 | 2007-04-18 | 特拉科斯有限公司 | Methods for pretreating a subject with extracorporeal photopheresis and/or apoptotic cells |
US7361310B1 (en) * | 2001-11-30 | 2008-04-22 | Northwestern University | Direct write nanolithographic deposition of nucleic acids from nanoscopic tips |
US8725418B2 (en) | 2002-03-25 | 2014-05-13 | Janssen Pharmaceutica, N.V. | Data mining of SNP databases for the selection of intragenic SNPs |
US7601493B2 (en) * | 2002-07-26 | 2009-10-13 | Nanogen, Inc. | Methods and apparatus for screening and detecting multiple genetic mutations |
US7452712B2 (en) | 2002-07-30 | 2008-11-18 | Applied Biosystems Inc. | Sample block apparatus and method of maintaining a microcard on a sample block |
CN102344960B (en) | 2002-09-06 | 2014-06-18 | 波士顿大学信托人 | Quantification of gene expression |
AU2003273640A1 (en) * | 2002-10-10 | 2004-05-04 | K.U. Leuven Research And Development | Autism gene |
EP3000899A1 (en) | 2002-12-04 | 2016-03-30 | Applied Biosystems, LLC | Multiplex amplification of polynucleotides |
EP1578952B1 (en) * | 2002-12-12 | 2011-11-23 | Nanosphere, Inc. | Direct snp detection with unamplified dna |
EP1590471A4 (en) | 2002-12-31 | 2009-12-09 | Metamorphix Inc | Compositions, methods and systems for inferring bovine traits |
US20040224331A1 (en) | 2003-01-17 | 2004-11-11 | The Trustees Of Boston University | Haplotype analysis |
CA2897376A1 (en) * | 2003-02-26 | 2004-09-10 | Radoje T. Drmanac | Modular system and probes for dna analysis |
EP1606419A1 (en) | 2003-03-18 | 2005-12-21 | Quantum Genetics Ireland Limited | Systems and methods for improving protein and milk production of dairy herds |
US20040191776A1 (en) * | 2003-03-21 | 2004-09-30 | Pei-Jer Chen | Method for genotyping and quantifying Hepatitis B Virus |
US20040203005A1 (en) * | 2003-04-14 | 2004-10-14 | White Wanda L. B. | Dual hybridization of complex nucleic acid samples for sequencing and single-nucleotide polymorphism identification |
WO2004111266A1 (en) | 2003-06-17 | 2004-12-23 | Human Genetic Signatures Pty Ltd | Methods for genome amplification |
CN1863927B (en) | 2003-09-04 | 2010-08-11 | 人类遗传标记控股有限公司 | Nucleic acid detection assay |
CN101985619B (en) | 2003-10-08 | 2014-08-20 | 波士顿大学信托人 | Methods for prenatal diagnosis of chromosomal abnormalities |
CA2543786A1 (en) * | 2003-10-24 | 2005-05-06 | Mmi Genomics, Inc. | Methods and systems for inferring traits to manage non-beef livestock |
US20060008815A1 (en) * | 2003-10-24 | 2006-01-12 | Metamorphix, Inc. | Compositions, methods, and systems for inferring canine breeds for genetic traits and verifying parentage of canine animals |
WO2005056834A1 (en) * | 2003-12-10 | 2005-06-23 | Olympus Corporation | Method of analyzing nucleic acid sequence |
EP1721014B1 (en) | 2004-02-18 | 2013-07-17 | Trustees Of Boston University | Method for detecting and quantifying rare mutations/polymorphisms |
MXPA06009452A (en) | 2004-02-19 | 2007-03-15 | Univ Alberta | Leptin promoter polymorphisms and uses thereof. |
WO2005085475A1 (en) | 2004-03-01 | 2005-09-15 | Applera Corporation | Methods, compositions and kits for use in polynucleotide amplification |
US8168777B2 (en) | 2004-04-29 | 2012-05-01 | Human Genetic Signatures Pty. Ltd. | Bisulphite reagent treatment of nucleic acid |
US20050255485A1 (en) * | 2004-05-14 | 2005-11-17 | Livak Kenneth J | Detection of gene duplications |
EP1766049B1 (en) * | 2004-06-11 | 2011-10-19 | Evotec AG | A method for detecting analytes in a sample |
WO2006026828A1 (en) | 2004-09-10 | 2006-03-16 | Human Genetic Signatures Pty Ltd | Amplification blocker comprising intercalating nucleic acids (tna) containing intercalating pseudonucleotides (ipn) |
US20060121491A1 (en) * | 2004-12-02 | 2006-06-08 | Wolber Paul K | Partially degenerate oligonucleotide standards and methods for generating the same |
KR101293713B1 (en) | 2004-12-03 | 2013-08-12 | 휴먼 제네틱 시그너처스 피티와이 엘티디 | Methods for simplifying microbial nucleic acids by chemical modification of cytosines |
WO2006116010A2 (en) * | 2005-04-21 | 2006-11-02 | Advandx, Inc. | Detection of virulence markers of staphylococci |
CN101203618B (en) | 2005-05-26 | 2013-03-13 | 人类遗传标记控股有限公司 | Isothermal strand displacement amplification using primers containing a non-regular base |
WO2007002567A2 (en) * | 2005-06-23 | 2007-01-04 | Nanosphere, Inc. | Selective isolation and concentration of nucleic acids from complex samples |
US20060292576A1 (en) * | 2005-06-23 | 2006-12-28 | Quest Diagnostics Investments Incorporated | Non-in situ hybridization method for detecting chromosomal abnormalities |
EP1943353B1 (en) | 2005-09-14 | 2011-11-02 | Human Genetic Signatures PTY Ltd | Assay for a health state |
JP2007117060A (en) * | 2005-10-31 | 2007-05-17 | Tohoku Univ | Method for discriminating silent mutation lineage of crop and method for discriminating place of production of agricultural crop |
US8076074B2 (en) * | 2005-11-29 | 2011-12-13 | Quest Diagnostics Investments Incorporated | Balanced translocation in comparative hybridization |
EP2617837A3 (en) | 2007-06-08 | 2013-10-23 | Biogen Idec MA Inc. | Biomarkers for predicting anti-TNF responsiveness or non-responsiveness |
WO2008157550A2 (en) * | 2007-06-20 | 2008-12-24 | Northwestern University | Patterning with compositions containing nanomaterials and polymers |
CA2690723A1 (en) * | 2007-08-08 | 2009-02-12 | Northwestern University | Independently-addressable, self-correcting inking for cantilever arrays |
US20090137417A1 (en) * | 2007-10-17 | 2009-05-28 | Michigan State University | Microarray-Based Gene Copy Number Analyses |
CA2706740C (en) | 2007-11-27 | 2017-01-17 | Human Genetic Signatures Pty Ltd | Enzymes for amplification and copying bisulphite modified nucleic acids |
US8093063B2 (en) | 2007-11-29 | 2012-01-10 | Quest Diagnostics Investments Incorporated | Assay for detecting genetic abnormalities in genomic nucleic acids |
EP2318552B1 (en) | 2008-09-05 | 2016-11-23 | TOMA Biosciences, Inc. | Methods for stratifying and annotating cancer drug treatment options |
WO2011100503A1 (en) | 2010-02-11 | 2011-08-18 | Dana Farber Cancer Institute, Inc. | Methods for predicting likelihood of responding to treatment |
EP2576823A1 (en) | 2010-06-04 | 2013-04-10 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Constitutively active prolactin receptor variants as prognostic markers and therapeutic targets to prevent progression of hormone-dependent cancers towards hormone-independence |
US20120070885A1 (en) * | 2010-09-21 | 2012-03-22 | Florida State University Research Foundation | Integrated device for analyzing aqueous samples using lipid multilayer gratings |
AU2011305445B2 (en) | 2010-09-24 | 2017-03-16 | The Board Of Trustees Of The Leland Stanford Junior University | Direct capture, amplification and sequencing of target DNA using immobilized primers |
US9732375B2 (en) | 2011-09-07 | 2017-08-15 | Human Genetic Signatures Pty. Ltd. | Molecular detection assay using direct treatment with a bisulphite reagent |
GB201208726D0 (en) * | 2012-05-17 | 2012-07-04 | Oxford Gene Tech Ip Ltd | Methods and materials |
US9540699B2 (en) | 2013-03-13 | 2017-01-10 | William Beaumont Hospital | Methods of diagnosing increased risk of developing MRSA |
US20150037787A1 (en) * | 2013-07-31 | 2015-02-05 | International Business Machines Corporation | Polynucleotide configuration for reliable electrical and optical sensing |
CN106029899B (en) * | 2013-09-30 | 2021-08-03 | 深圳华大基因股份有限公司 | Method, system and computer readable medium for determining SNP information in predetermined region of chromosome |
DK3066219T3 (en) * | 2013-11-08 | 2019-03-11 | Ionis Pharmaceuticals Inc | METHODS FOR DETECTING OIGONUCLEOTIDES |
EP3277836B1 (en) | 2015-04-02 | 2019-02-27 | HMNC Value GmbH | Method of treatment using genetic predictors of a response to treatment with ssr-125543 |
GB2569478B (en) * | 2016-10-20 | 2022-06-01 | Hitachi High Tech Corp | Method for treating biomolecules and method for analyzing biomolecules |
CN110678557A (en) | 2017-03-31 | 2020-01-10 | 玛赛拉·基亚里 | Genotyping of mutations by in-tube hybridization in combination with universal tag-microarray |
WO2022003609A1 (en) * | 2020-07-01 | 2022-01-06 | Biorchestra Co., Ltd. | Snp diagnostic methods |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474895A (en) * | 1990-11-14 | 1995-12-12 | Siska Diagnostics Inc. | Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor |
WO1996031622A1 (en) * | 1995-04-07 | 1996-10-10 | Oxford Gene Technology Limited | Detecting dna sequence variations |
US5633134A (en) * | 1992-10-06 | 1997-05-27 | Ig Laboratories, Inc. | Method for simultaneously detecting multiple mutations in a DNA sample |
WO1997022720A1 (en) * | 1995-12-21 | 1997-06-26 | Kenneth Loren Beattie | Arbitrary sequence oligonucleotide fingerprinting |
EP0846776A2 (en) * | 1996-12-06 | 1998-06-10 | Vysis, Inc. | Devices and methods for detecting multiple analytes in samples |
US5801155A (en) * | 1995-04-03 | 1998-09-01 | Epoch Pharmaceuticals, Inc. | Covalently linked oligonucleotide minor grove binder conjugates |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5700637A (en) * | 1988-05-03 | 1997-12-23 | Isis Innovation Limited | Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays |
US5627032A (en) * | 1990-12-24 | 1997-05-06 | Ulanovsky; Levy | Composite primers for nucleic acids |
US6017696A (en) * | 1993-11-01 | 2000-01-25 | Nanogen, Inc. | Methods for electronic stringency control for molecular biological analysis and diagnostics |
US5976798A (en) * | 1994-03-30 | 1999-11-02 | Mitokor | Methods for detecting mitochondrial mutations diagnostic for Alzheimer's disease and methods for determining heteroplasmy of mitochondrial nucleic acid |
US5830645A (en) * | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
US6051379A (en) * | 1997-09-23 | 2000-04-18 | Oncormed, Inc. | Cancer susceptibility mutations of BRCA2 |
-
1999
- 1999-02-26 US US09/259,898 patent/US6410231B1/en not_active Expired - Fee Related
-
2000
- 2000-02-24 CA CA002362619A patent/CA2362619A1/en not_active Abandoned
- 2000-02-24 EP EP00914711A patent/EP1166076A4/en not_active Withdrawn
- 2000-02-24 JP JP2000601417A patent/JP2002537780A/en active Pending
- 2000-02-24 AU AU36065/00A patent/AU755398B2/en not_active Ceased
- 2000-02-24 WO PCT/US2000/004876 patent/WO2000050869A2/en not_active Application Discontinuation
-
2002
- 2002-06-24 US US10/178,318 patent/US20030059813A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474895A (en) * | 1990-11-14 | 1995-12-12 | Siska Diagnostics Inc. | Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor |
US5633134A (en) * | 1992-10-06 | 1997-05-27 | Ig Laboratories, Inc. | Method for simultaneously detecting multiple mutations in a DNA sample |
US5801155A (en) * | 1995-04-03 | 1998-09-01 | Epoch Pharmaceuticals, Inc. | Covalently linked oligonucleotide minor grove binder conjugates |
WO1996031622A1 (en) * | 1995-04-07 | 1996-10-10 | Oxford Gene Technology Limited | Detecting dna sequence variations |
WO1997022720A1 (en) * | 1995-12-21 | 1997-06-26 | Kenneth Loren Beattie | Arbitrary sequence oligonucleotide fingerprinting |
EP0846776A2 (en) * | 1996-12-06 | 1998-06-10 | Vysis, Inc. | Devices and methods for detecting multiple analytes in samples |
Non-Patent Citations (3)
Title |
---|
DAHLEN P ET AL: "SENSITIVE DETECTION OF GENES BY SANDWICH HYBRIDIZATION AND TIME-RESOLVED FLUOROMETRY", MOLECULAR AND CELLULAR PROBES, ACADEMIC PRESS, LONDON, GB, vol. 1, no. 2, June 1987 (1987-06-01), pages 159 - 168, XP001029639, ISSN: 0890-8508 * |
RAMSAY G: "DNA CHIPS: STATE-OF-THE ART", NATURE BIOTECHNOLOGY, NATURE PUBLISHING, US, vol. 16, 1998, pages 40 - 44, XP000198575, ISSN: 1087-0156 * |
SHUBER A P ET AL: "HIGH THROUGHPUT PARALLEL ANALYSIS OF HUNDREDS OF PATIENT SAMPLES FOR MORE THAN 100 MUTATIONS IN MULTIPLE DISEASE GENES", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 6, no. 3, 1 March 1997 (1997-03-01), pages 337 - 347, XP000673446, ISSN: 0964-6906 * |
Also Published As
Publication number | Publication date |
---|---|
WO2000050869A2 (en) | 2000-08-31 |
US20030059813A1 (en) | 2003-03-27 |
AU755398B2 (en) | 2002-12-12 |
EP1166076A2 (en) | 2002-01-02 |
US6410231B1 (en) | 2002-06-25 |
JP2002537780A (en) | 2002-11-12 |
AU3606500A (en) | 2000-09-14 |
CA2362619A1 (en) | 2000-08-31 |
WO2000050869A3 (en) | 2000-11-02 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20010917 |
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AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20040914 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7G 01N 1/00 A Ipc: 7C 12Q 1/68 B |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20041201 |