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EP1163252A4 - Compositions, kits et procedes concernant le gene fez1 de l'homme, nouveau gene suppresseur des tumeurs - Google Patents

Compositions, kits et procedes concernant le gene fez1 de l'homme, nouveau gene suppresseur des tumeurs

Info

Publication number
EP1163252A4
EP1163252A4 EP00912007A EP00912007A EP1163252A4 EP 1163252 A4 EP1163252 A4 EP 1163252A4 EP 00912007 A EP00912007 A EP 00912007A EP 00912007 A EP00912007 A EP 00912007A EP 1163252 A4 EP1163252 A4 EP 1163252A4
Authority
EP
European Patent Office
Prior art keywords
gene
kits
compositions
tumor suppressor
methods relating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00912007A
Other languages
German (de)
English (en)
Other versions
EP1163252A2 (fr
Inventor
Carlo M Croce
Hideshi Ishii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thomas Jefferson University
Original Assignee
Thomas Jefferson University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Jefferson University filed Critical Thomas Jefferson University
Publication of EP1163252A2 publication Critical patent/EP1163252A2/fr
Publication of EP1163252A4 publication Critical patent/EP1163252A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EP00912007A 1999-02-25 2000-02-25 Compositions, kits et procedes concernant le gene fez1 de l'homme, nouveau gene suppresseur des tumeurs Withdrawn EP1163252A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12153799P 1999-02-25 1999-02-25
US121537P 1999-02-25
PCT/US2000/004950 WO2000050565A2 (fr) 1999-02-25 2000-02-25 Compositions, kits et procedes concernant le gene fez1 de l'homme, nouveau gene suppresseur des tumeurs

Publications (2)

Publication Number Publication Date
EP1163252A2 EP1163252A2 (fr) 2001-12-19
EP1163252A4 true EP1163252A4 (fr) 2004-04-07

Family

ID=22397335

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00912007A Withdrawn EP1163252A4 (fr) 1999-02-25 2000-02-25 Compositions, kits et procedes concernant le gene fez1 de l'homme, nouveau gene suppresseur des tumeurs

Country Status (4)

Country Link
EP (1) EP1163252A4 (fr)
JP (1) JP2003508011A (fr)
CA (1) CA2361396A1 (fr)
WO (1) WO2000050565A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141417B1 (en) 1999-02-25 2006-11-28 Thomas Jefferson University Compositions, kits, and methods relating to the human FEZ1 gene, a novel tumor suppressor gene
AU2008266014B2 (en) 2007-06-15 2013-06-06 The Ohio State University Research Foundation Oncogenic ALL-1 fusion proteins for targeting drosha-mediated microRNA processing
EP2650383A1 (fr) 2007-08-03 2013-10-16 The Ohio State University Research Foundation Régions ultraconservées codant de l'ARNnm
CN102137927B (zh) 2007-10-26 2014-03-12 俄亥俄州立大学研究基金会 鉴定脆性组氨酸三联体(Fhit)相互作用的方法及其用途
CN102149827B (zh) 2008-06-11 2014-08-20 由卫生与公众服务部代表的美利坚合众国政府 MiR-26家族作为肝细胞癌和对治疗的应答性的预测性标志物的用途
WO2011063382A1 (fr) 2009-11-23 2011-05-26 The Ohio State University Substances et procédés pouvant s'utiliser pour agir sur la croissance, la migration, et l'invasion de cellules tumorales
EP2637673B1 (fr) 2010-11-12 2016-10-26 The Ohio State University Research Foundation Procédés relatifs aux microarn-21 et réparation de désappariement dans le cancer colorectal
CA2817982C (fr) 2010-11-15 2020-06-30 The Regents Of The University Of Michigan Systemes mucoadhesifs a liberation controlee
EP2683387A4 (fr) 2011-03-07 2014-09-03 Univ Ohio State Activité mutatrice induite par l'inflammation des liaisons au microarn-155 (mir-155) et le cancer
AU2012323924A1 (en) 2011-10-14 2014-05-29 The Ohio State University Methods and materials related to ovarian cancer
JP2015501843A (ja) 2011-12-13 2015-01-19 オハイオ・ステイト・イノベーション・ファウンデーション ｍｉＲ−２１およびｍｉＲ−２９ａ、エキソソーム阻害、およびがん転移に関する方法および組成物
AU2013209477B2 (en) 2012-01-20 2016-12-08 The Ohio State University Breast cancer biomarker signatures for invasiveness and prognosis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055448A1 (fr) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Acides nucleiques, proteines et anticorps
WO2001055300A2 (fr) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Acides nucleiques, proteines et anticorps

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055448A1 (fr) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Acides nucleiques, proteines et anticorps
WO2001055300A2 (fr) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Acides nucleiques, proteines et anticorps

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 July 1998 (1998-07-01), "ox62e04.x1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:1660926 3', mRNA sequence", XP002266794, Database accession no. AI042490 *
ISHII H ET AL: "The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. UNITED STATES 30 MAR 1999, vol. 96, no. 7, 30 March 1999 (1999-03-30), pages 3928 - 3933, XP002266793, ISSN: 0027-8424 *
See also references of WO0050565A3 *

Also Published As

Publication number Publication date
JP2003508011A (ja) 2003-03-04
CA2361396A1 (fr) 2000-08-31
WO2000050565A3 (fr) 2000-12-07
EP1163252A2 (fr) 2001-12-19
WO2000050565A2 (fr) 2000-08-31

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010912

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 07K 14/47 A

A4 Supplementary search report drawn up and despatched

Effective date: 20040219

RTI1 Title (correction)

Free format text: COMPOSITIONS, KITS, AND METHODS RELATING TO THE HUMAN FEZ1 GENE, A NOVEL TUMOR SUPPRESSOR GENE

17Q First examination report despatched

Effective date: 20051012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080902