EP0854931A4 - Coiled-coil heterodimer methods and compositions for the detection and purification of expressed proteins - Google Patents

Coiled-coil heterodimer methods and compositions for the detection and purification of expressed proteins

Info

Publication number: EP0854931A4
Authority: EP; European Patent Office
Prior art keywords: coiled; purification; compositions; detection; methods
Prior art date: 1995-10-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP96934080A

Other languages

German (de)

French (fr)

Other versions

EP0854931A1 (en

Inventor

Michael E Houston Jr

Lei Yu

Daisy Bautista

Robert S Hodges

Brian Tripet

Paul J Cachia

Randall T Irvin

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pence Inc

Original Assignee

Pence Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-06

Filing date

1996-10-04

Publication date

2002-02-13

1996-10-04 Application filed by Pence Inc filed Critical Pence Inc

1998-07-29 Publication of EP0854931A1 publication Critical patent/EP0854931A1/en

2002-02-13 Publication of EP0854931A4 publication Critical patent/EP0854931A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Crystallography & Structural Chemistry (AREA)
Peptides Or Proteins (AREA)
Investigating Or Analysing Biological Materials (AREA)

EP96934080A 1995-10-06 1996-10-04 Coiled-coil heterodimer methods and compositions for the detection and purification of expressed proteins Withdrawn EP0854931A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US54039795A	1995-10-06	1995-10-06
US540397		1995-10-06
PCT/US1996/016032 WO1997012988A1 (en)	1995-10-06	1996-10-04	Coiled-coil heterodimer methods and compositions for the detection and purification of expressed proteins

Publications (2)

Publication Number	Publication Date
EP0854931A1 EP0854931A1 (en)	1998-07-29
EP0854931A4 true EP0854931A4 (en)	2002-02-13

Family

ID=24155285

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP96934080A Withdrawn EP0854931A4 (en)	1995-10-06	1996-10-04	Coiled-coil heterodimer methods and compositions for the detection and purification of expressed proteins

Country Status (4)

Country	Link
EP (1)	EP0854931A4 (en)
JP (1)	JPH11512620A (en)
AU (1)	AU695679B2 (en)
WO (1)	WO1997012988A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6271198B1 (en)	1996-11-06	2001-08-07	Genentech, Inc.	Constrained helical peptides and methods of making same
GB9714680D0 (en)	1997-07-11	1997-09-17	Medical Res Council	Recombinant production of proteins
GB9714681D0 (en) *	1997-07-11	1997-09-17	Medical Res Council	Recombinant production of proteins
US7105307B2 (en)	1997-08-30	2006-09-12	Cyclacel, Ltd.	Compositions and methods for screening for modulators of enzymatic activity
GB9718358D0 (en) *	1997-08-30	1997-11-05	Univ Leeds	Chemical modification
DE19815331A1 (en) *	1998-04-06	1999-10-14	Karlsruhe Forschzent	Transcription factors and their use
WO1999065511A2 (en)	1998-06-12	1999-12-23	The Governors Of The University Of Alberta	Composition and method for treatment of pseudomonas infection
GB2341115B (en) *	1998-09-04	2002-02-06	Actinova Ltd	Chromatography
US6380365B1 (en) *	1998-09-04	2002-04-30	Affitech As	Temperature dependent ligand facilitated purification of proteins
US6852694B2 (en)	2001-02-21	2005-02-08	Medtronic Minimed, Inc.	Stabilized insulin formulations
GB0315993D0 (en) *	2003-07-08	2003-08-13	Sussex Ip Ltd	Peptide-based linker
WO2005024035A1 (en) *	2003-09-05	2005-03-17	National Research Council Of Canada	Coiled-coil fusion proteins comprising cell receptor domains
US7786261B2 (en)	2004-09-02	2010-08-31	National Research Council Of Canada	Coiled-coil fusion proteins comprising cell receptor domains
EP2528622A2 (en)	2010-01-26	2012-12-05	The Regents of the University of Colorado	Influenza virus epitopes templated into double-stranded coiled coils and use thereof in immunization
CN103154025B (en) *	2010-08-02	2015-07-01	宏观基因有限公司	Covalent diabodies and uses thereof
KR20210087959A (en) *	2018-11-02	2021-07-13	유니버시티 오브 워싱톤	orthogonal protein heterodimer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0491362A2 (en) *	1990-12-19	1992-06-24	BEHRINGWERKE Aktiengesellschaft	Use of peptide pairs with extremely high mutual specific affinity in the domain of in-vitro diagnostics
WO1995031480A1 (en) *	1994-05-18	1995-11-23	S.P.I. Synthetic Peptides Incorporated	Heterodimer polypeptide immunogen carrier composition and method

1996
- 1996-10-04 EP EP96934080A patent/EP0854931A4/en not_active Withdrawn
- 1996-10-04 AU AU72584/96A patent/AU695679B2/en not_active Ceased
- 1996-10-04 JP JP9514507A patent/JPH11512620A/en active Pending
- 1996-10-04 WO PCT/US1996/016032 patent/WO1997012988A1/en not_active Application Discontinuation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0491362A2 (en) *	1990-12-19	1992-06-24	BEHRINGWERKE Aktiengesellschaft	Use of peptide pairs with extremely high mutual specific affinity in the domain of in-vitro diagnostics
WO1995031480A1 (en) *	1994-05-18	1995-11-23	S.P.I. Synthetic Peptides Incorporated	Heterodimer polypeptide immunogen carrier composition and method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GRADDIS TJ ET AL.: "Controlled formation of model homo- and heterodimer coiled coil polypeptides", BIOCHEMISTRY., vol. 32, 1993, AMERICAN CHEMICAL SOCIETY. EASTON, PA., US, pages 12664 - 12671, XP001041686, ISSN: 0006-2960 *
HODGES R S: "DE NOVO DESIGN OF ALPHA-HELICAL PROTEINS: BASIC RESEARCH TO MEDICALAPPLICATIONS", BIOCHEMISTRY AND CELL BIOLOGY. BIOCHIMIE ET BIOLOGIE CELLULAIRE, XX, XX, vol. 74, no. 2, 17 June 1995 (1995-06-17), pages 133 - 154, XP002185479, ISSN: 0829-8211 *
See also references of WO9712988A1 *

Also Published As

Publication number	Publication date
EP0854931A1 (en)	1998-07-29
AU695679B2 (en)	1998-08-20
JPH11512620A (en)	1999-11-02
AU7258496A (en)	1997-04-28
WO1997012988A1 (en)	1997-04-10

Publication	Publication Date	Title
HUP9900422A3 (en)	2002-11-28	Novel protein and methods for the production of the same
HUP9802678A3 (en)	1999-12-28	Bicyclic amino derivatives and pgd2 antagonist containing the same
DE69624267D1 (en)	2002-11-14	MULTI-MEDIA RECEIVER AND SYSTEM FOR THIS
ZA964733B (en)	1997-01-07	Ob protein compositions and methods
NO308559B1 (en)	2000-09-25	Procedure for delivery of ice slurry and system for carrying out the same
EP0854931A4 (en)	2002-02-13	Coiled-coil heterodimer methods and compositions for the detection and purification of expressed proteins
GB9716773D0 (en)	1997-10-15	Detection of foreign bodies
EP0897523A4 (en)	1999-07-28	Semiconductor bridge device and method of making the same
GB9510830D0 (en)	1995-07-19	Proteins
AU1501697A (en)	1997-09-04	Improved method for the detection of protein
AU4013495A (en)	1996-05-23	Chemokine-like proteins and methods of use
IL123320A0 (en)	1998-09-24	Detection of hypoprathyroidism
GB2304576B (en)	1999-11-24	Reduction of airborne contaminants
GB2317296B (en)	2000-06-28	Detection of scratches
GB2298919B (en)	1999-07-28	Method and system for use in the measurement of velocity
GB2315869A8 (en)	2001-04-11	Evaluation of particulate contaminants
SG69985A1 (en)	2000-01-25	The process of asphalt purification and the composition of modified asphalt
HUP9801330A3 (en)	2000-11-28	Novel pka-binding proteins and uses thereof
IL128746A0 (en)	2000-01-31	Ptx-sensitive g proteins their preparation and use
IL112839A0 (en)	1995-07-31	Methods for the purification of halofluorocarbons
GB2309155B (en)	1999-10-13	Point of sale systems
AU2869897A (en)	1998-02-05	Process of recovering and purifying protein
AU3521595A (en)	1996-03-29	Method for detection of malfolded protein
GB9825065D0 (en)	1999-01-13	Method of expolosives detection
AU4524093A (en)	1993-12-30	Compositions and methods for detection of hormone-binding proteins

Legal Events

Date	Code	Title	Description
1998-06-12	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1998-07-29	17P	Request for examination filed	Effective date: 19980427
1998-07-29	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2002-02-13	A4	Supplementary search report drawn up and despatched	Effective date: 20020102
2002-02-13	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2003-01-15	17Q	First examination report despatched	Effective date: 20021128
2006-01-13	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2006-03-01	18D	Application deemed to be withdrawn	Effective date: 20050819