EP0763202A4 - Encoded combinatorial libraries - Google Patents

Encoded combinatorial libraries

Info

Publication number: EP0763202A4
Authority: EP; European Patent Office
Prior art keywords: combinatorial libraries; encoded combinatorial; encoded; libraries; combinatorial
Prior art date: 1994-05-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP95920576A

Other languages

German (de)

French (fr)

Other versions

EP0763202A1 (en

Inventor

Dennis Shinji Yamashita

Joseph Weinstock

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-23

Filing date

1995-05-23

Publication date

1998-12-09

1995-05-23 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

1997-03-19 Publication of EP0763202A1 publication Critical patent/EP0763202A1/en

1998-12-09 Publication of EP0763202A4 publication Critical patent/EP0763202A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00592—Split-and-pool, mix-and-divide processes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Analytical Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Investigating Or Analysing Biological Materials (AREA)

EP95920576A 1994-05-23 1995-05-23 Encoded combinatorial libraries Withdrawn EP0763202A4 (en)

Applications Claiming Priority (9)

Application Number	Priority Date	Filing Date	Title
US24779394A	1994-05-23	1994-05-23
US247793		1994-05-23
US26733394A	1994-06-28	1994-06-28
US267333		1994-06-28
US38254295A	1995-02-01	1995-02-01
US382542		1995-02-01
US41043695A	1995-03-23	1995-03-23
US410436		1995-03-23
PCT/US1995/006392 WO1995032425A1 (en)	1994-05-23	1995-05-23	Encoded combinatorial libraries

Publications (2)

Publication Number	Publication Date
EP0763202A1 EP0763202A1 (en)	1997-03-19
EP0763202A4 true EP0763202A4 (en)	1998-12-09

Family

ID=27500266

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP95920576A Withdrawn EP0763202A4 (en)	1994-05-23	1995-05-23	Encoded combinatorial libraries

Country Status (3)

Country	Link
EP (1)	EP0763202A4 (en)
JP (1)	JPH10500951A (en)
WO (1)	WO1995032425A1 (en)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5866341A (en) *	1996-04-03	1999-02-02	Chugai Pharmaceutical Co., Ltd.	Compositions and methods for screening drug libraries
US6096496A (en) *	1997-06-19	2000-08-01	Frankel; Robert D.	Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis
EP1002235A1 (en) *	1997-08-01	2000-05-24	Novalon Pharmaceutical Corporation	Method of identifying and developing drug leads
EP1036332B1 (en) *	1997-12-04	2005-07-13	Amersham Biosciences UK Limited	Multiple assay method
US6455263B2 (en) *	1998-03-24	2002-09-24	Rigel Pharmaceuticals, Inc.	Small molecule library screening using FACS
US6720190B1 (en)	1998-03-27	2004-04-13	Ole Hindsgaul	Methods for screening compound libraries
CA2240325A1 (en)	1998-03-27	1998-11-14	Synsorb Biotech, Inc.	Methods for screening compound libraries
US6613575B1 (en)	1998-03-27	2003-09-02	Ole Hindsgaul	Methods for screening compound libraries
US6054047A (en) *	1998-03-27	2000-04-25	Synsorb Biotech, Inc.	Apparatus for screening compound libraries
DE69941193D1 (en)	1998-08-17	2009-09-10	Bristol Myers Squibb Co	IDENTIFICATION OF COMPOUND PROTEIN INTERACTIONS WITH LIBRARIES OF COUPLED PROTEIN NUCLEIC ACID MOLECULES
US6642062B2 (en) *	1998-09-03	2003-11-04	Trellis Bioinformatics, Inc.	Multihued labels
AUPP737298A0 (en) *	1998-11-30	1998-12-24	University Of Queensland, The	Combinatorial libraries
AU4202400A (en) *	1999-04-09	2000-11-14	Glaxo Group Limited	Encoding scheme for solid phase chemical libraries
CA2366093A1 (en) *	1999-04-15	2000-10-26	Ilya Ravkin	Combinatorial chemical library supports having indicia at coding positions and methods of use
US7022479B2 (en)	2000-01-24	2006-04-04	Compound Therapeutics, Inc.	Sensitive, multiplexed diagnostic assays for protein analysis
CA2396810A1 (en)	2000-01-24	2001-07-26	Phylos, Inc.	Sensitive, multiplexed diagnostic assays for protein analysis
MXPA02007576A (en) *	2000-02-07	2004-08-23	Kyowa Medex Co Ltd	Method for detecting substance.
WO2001080622A2 (en) *	2000-04-26	2001-11-01	Streamline Proteomics	Apparatus and methods for assays of one or more analytes
ES2284833T3 (en) *	2001-02-13	2007-11-16	Pronostics Limited	BIOCHEMICAL PROCEDURE AND APPLIANCE TO DETECT GENETIC CHARACTERISTICS.
JP2004527735A (en) *	2001-02-13	2004-09-09	スマートビードテクノロジーズリミティド	Biochemical methods and devices for detecting protein properties
CA2550902C (en)	2003-12-22	2013-06-25	Versamatrix A/S	Apparatus and methods for analysis and sorting of particles such as polymer beads
EP1701784A1 (en)	2003-12-22	2006-09-20	VersaMatrix A/S	Identification of encoded beads
US8460879B2 (en)	2006-02-21	2013-06-11	The Trustees Of Tufts College	Methods and arrays for target analyte detection and determination of target analyte concentration in solution
US11237171B2 (en)	2006-02-21	2022-02-01	Trustees Of Tufts College	Methods and arrays for target analyte detection and determination of target analyte concentration in solution
WO2008114020A2 (en)	2007-03-22	2008-09-25	Heptares Therapeutics Limited	Mutant g-protein coupled receptors and methods for selecting them
EP2201374B1 (en)	2007-08-30	2015-10-07	Trustees Of Tufts College	Methods for determining the concentration of an analyte in solution.
GB0724051D0 (en)	2007-12-08	2008-01-16	Medical Res Council	Mutant proteins and methods for producing them
GB0724860D0 (en)	2007-12-20	2008-01-30	Heptares Therapeutics Ltd	Screening
GB0802474D0 (en)	2008-02-11	2008-03-19	Heptares Therapeutics Ltd	Mutant proteins and methods for selecting them
US8222047B2 (en)	2008-09-23	2012-07-17	Quanterix Corporation	Ultra-sensitive detection of molecules on single molecule arrays
GB0904904D0 (en)	2009-03-23	2009-05-06	Univ Leiden Medical Ct	Angiogenesis methods, medicaments and agents
GB0910725D0 (en)	2009-06-22	2009-08-05	Heptares Therapeutics Ltd	Mutant proteins and methods for producing them
GB201002082D0 (en)	2010-02-09	2010-03-24	Univ Leiden Medical Ct	Biological material
US9678068B2 (en)	2010-03-01	2017-06-13	Quanterix Corporation	Ultra-sensitive detection of molecules using dual detection methods
EP2542890B1 (en)	2010-03-01	2015-05-06	Quanterix Corporation	Methods for extending dynamic range in assays for the detection of molecules or particles
US8236574B2 (en)	2010-03-01	2012-08-07	Quanterix Corporation	Ultra-sensitive detection of molecules or particles using beads or other capture objects
US8415171B2 (en)	2010-03-01	2013-04-09	Quanterix Corporation	Methods and systems for extending dynamic range in assays for the detection of molecules or particles
WO2012093258A2 (en)	2011-01-05	2012-07-12	Imperial Innovations Limited	Treatment and screening
US9952237B2 (en)	2011-01-28	2018-04-24	Quanterix Corporation	Systems, devices, and methods for ultra-sensitive detection of molecules or particles
US20140302532A1 (en)	2011-04-12	2014-10-09	Quanterix Corporation	Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury
WO2014113502A1 (en)	2013-01-15	2014-07-24	Quanterix Corporation	Detection of dna or rna using single molecule arrays and other techniques
GB201501004D0 (en)	2015-01-21	2015-03-04	Cancer Rec Tech Ltd	Inhibitors
GB201601690D0 (en)	2016-01-29	2016-03-16	Heptares Therapeutics Ltd	G proteins
GB201814451D0 (en)	2018-09-05	2018-10-17	Valerie Nicholas Carl Kristoffer	Methods

1995
- 1995-05-23 EP EP95920576A patent/EP0763202A4/en not_active Withdrawn
- 1995-05-23 WO PCT/US1995/006392 patent/WO1995032425A1/en not_active Application Discontinuation
- 1995-05-23 JP JP7530459A patent/JPH10500951A/en active Pending

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9532425A1 *

Also Published As

Publication number	Publication date
EP0763202A1 (en)	1997-03-19
WO1995032425A1 (en)	1995-11-30
JPH10500951A (en)	1998-01-27

Publication	Publication Date	Title
EP0763202A4 (en)	1998-12-09	Encoded combinatorial libraries
EP0758313A4 (en)	1999-09-15	Combinatorial dihydrobenzopyran library
HU9602800D0 (en)	1996-11-28	Complex combinatorial chemical libraries encoded with tags
EP0864087A4 (en)	1999-04-07	Combinatorial dihydrobenzopyran library
IL135227A0 (en)	2001-05-20	Moving microdroplets
AU3272295A (en)	1996-02-22	Soluble combinatorial libraries
GB2301624B (en)	1999-01-06	Handcuffs
AUPP737298A0 (en)	1998-12-24	Combinatorial libraries
IL135039A0 (en)	2001-05-20	Combinatorial antisense library
AU8849398A (en)	1999-03-16	Combinatorial library
GB9515300D0 (en)	1995-09-20	Catalyst
GB2297551B (en)	1997-05-07	Labelled chemical libraries
AU1093197A (en)	1997-07-14	Combinatorial libraries
AU7624298A (en)	1998-06-29	Aminobenzenedicarboxylic acid-based combinatorial libraries
EP0950114A4 (en)	2004-07-28	Encoding of organometallic libraries
EP1135023A4 (en)	2003-03-05	Aminobenzisoxazole compounds and libraries thereof
GB9721353D0 (en)	1997-12-10	Bi-directional conversion library
GB9517570D0 (en)	1995-11-01	Mixtures
GB9601293D0 (en)	1996-03-27	Chemical synthesis
GB9313548D0 (en)	1993-08-11	Chemisynthetic libraries
GB9606820D0 (en)	1996-06-05	Transcription factor combinatorial libraries
GB9413734D0 (en)	1994-08-24	Encoding data
GB2317576B (en)	2000-02-16	Cycles
GB9607116D0 (en)	1996-06-12	Devices for combinatorial synthesis
GB9502333D0 (en)	1995-03-29	Desiccants

Legal Events

Date	Code	Title	Description
1997-01-31	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1997-03-19	17P	Request for examination filed	Effective date: 19961206
1997-03-19	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): BE CH DE FR GB IT LI NL
1998-12-09	A4	Supplementary search report drawn up and despatched	Effective date: 19981027
1998-12-09	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): BE CH DE FR GB IT LI NL
1998-12-09	RHK1	Main classification (correction)	Ipc: C07K 1/04
2001-01-31	17Q	First examination report despatched	Effective date: 20001219
2003-07-25	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2003-09-10	18D	Application deemed to be withdrawn	Effective date: 20030211