EP0689450A4 - Composes bloquant les vannes a potassium et leur utilisation - Google Patents
Composes bloquant les vannes a potassium et leur utilisationInfo
- Publication number
- EP0689450A4 EP0689450A4 EP94911588A EP94911588A EP0689450A4 EP 0689450 A4 EP0689450 A4 EP 0689450A4 EP 94911588 A EP94911588 A EP 94911588A EP 94911588 A EP94911588 A EP 94911588A EP 0689450 A4 EP0689450 A4 EP 0689450A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- potassium channel
- channel blocking
- blocking compounds
- compounds
- potassium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Insects & Arthropods (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Agronomy & Crop Science (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3338893A | 1993-03-18 | 1993-03-18 | |
US33388 | 1993-03-18 | ||
PCT/US1994/002750 WO1994021278A1 (fr) | 1993-03-18 | 1994-03-14 | Composes bloquant les vannes a potassium et leur utilisation |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0689450A1 EP0689450A1 (fr) | 1996-01-03 |
EP0689450A4 true EP0689450A4 (fr) | 1997-05-21 |
Family
ID=21870134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94911588A Withdrawn EP0689450A4 (fr) | 1993-03-18 | 1994-03-14 | Composes bloquant les vannes a potassium et leur utilisation |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0689450A4 (fr) |
JP (1) | JPH08508250A (fr) |
CN (1) | CN1125402A (fr) |
AU (1) | AU6407594A (fr) |
CA (1) | CA2158051A1 (fr) |
WO (1) | WO1994021278A1 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60112424T2 (de) * | 2000-05-10 | 2006-05-24 | Centre National De La Recherche Scientifique (Cnrs) | Protonen-abhängiges na+-kanal hemmendes polypeptid |
EP2383280A1 (fr) | 2002-09-23 | 2011-11-02 | E. I. du Pont de Nemours and Company | Système d'expression pour les canaux d'ion toxiques, par example de récepteurs de la ryanodine |
BRPI0605484A8 (pt) | 2006-11-21 | 2017-03-07 | Fund Amparo Pesquisa Estado Minas Gerais Fapemig | Toxina ph(alfa)1b, cdna do gene da toxina ph(alfa)1b, composições farmacêuticas contendo a toxina ph(alfa)1b, processo para sua obtenção, processo para obtenção do cdna, e produto |
CN106146639B (zh) * | 2015-04-21 | 2019-05-03 | 湖南师范大学 | 一种来源于雷氏大疣蛛毒液的钾离子通道抑制剂 |
EP3694432B1 (fr) | 2017-10-13 | 2024-05-01 | Mayo Foundation for Medical Education and Research | Dispositifs d'électroporation pour le traitement d'une fibrillation ventriculaire |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4925664A (en) * | 1986-10-20 | 1990-05-15 | University Of Utah | Spider toxins and methods for their use as blockers of calcium channels and amino acid receptor function |
WO1994010195A1 (fr) * | 1992-10-30 | 1994-05-11 | Pfizer Inc. | Polypeptides provenant du venin de l'heteropoda venatoria et bloquant les canaux calciques |
-
1994
- 1994-03-14 EP EP94911588A patent/EP0689450A4/fr not_active Withdrawn
- 1994-03-14 JP JP6521163A patent/JPH08508250A/ja active Pending
- 1994-03-14 WO PCT/US1994/002750 patent/WO1994021278A1/fr not_active Application Discontinuation
- 1994-03-14 AU AU64075/94A patent/AU6407594A/en not_active Abandoned
- 1994-03-14 CN CN94192030A patent/CN1125402A/zh active Pending
- 1994-03-14 CA CA002158051A patent/CA2158051A1/fr not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4925664A (en) * | 1986-10-20 | 1990-05-15 | University Of Utah | Spider toxins and methods for their use as blockers of calcium channels and amino acid receptor function |
WO1994010195A1 (fr) * | 1992-10-30 | 1994-05-11 | Pfizer Inc. | Polypeptides provenant du venin de l'heteropoda venatoria et bloquant les canaux calciques |
Non-Patent Citations (2)
Title |
---|
LAVRETSKY E.ET AL.: "A group of Potassium-Channel Blockers-Acetylcholine Releasers: New Potentials for Alzheimer Disease? A Reviewse", JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, vol. 12, no. 2, April 1992 (1992-04-01), pages 110 - 118, XP000647340 * |
See also references of WO9421278A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0689450A1 (fr) | 1996-01-03 |
WO1994021278A1 (fr) | 1994-09-29 |
CN1125402A (zh) | 1996-06-26 |
JPH08508250A (ja) | 1996-09-03 |
CA2158051A1 (fr) | 1994-09-29 |
AU6407594A (en) | 1994-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19951018 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19970407 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19981001 |