EP0689450A4 - Composes bloquant les vannes a potassium et leur utilisation - Google Patents

Composes bloquant les vannes a potassium et leur utilisation

Info

Publication number: EP0689450A4
Authority: EP; European Patent Office
Prior art keywords: potassium channel; channel blocking; blocking compounds; compounds; potassium
Prior art date: 1993-03-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP94911588A

Other languages

German (de)

English (en)

Other versions

EP0689450A1 (fr

Inventor

Michael C Sanguinetti

Alan L Mueller

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Shire NPS Pharmaceuticals Inc

Original Assignee

NPS Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-18

Filing date

1994-03-14

Publication date

1997-05-21

1994-03-14 Application filed by NPS Pharmaceuticals Inc filed Critical NPS Pharmaceuticals Inc

1996-01-03 Publication of EP0689450A1 publication Critical patent/EP0689450A1/fr

1997-05-21 Publication of EP0689450A4 publication Critical patent/EP0689450A4/fr

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Insects & Arthropods (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Tropical Medicine & Parasitology (AREA)
Cell Biology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Immunology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Environmental Sciences (AREA)
Wood Science & Technology (AREA)
Dentistry (AREA)
Virology (AREA)
Gastroenterology & Hepatology (AREA)
Agronomy & Crop Science (AREA)

EP94911588A 1993-03-18 1994-03-14 Composes bloquant les vannes a potassium et leur utilisation Withdrawn EP0689450A4 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US3338893A	1993-03-18	1993-03-18
US33388		1993-03-18
PCT/US1994/002750 WO1994021278A1 (fr)	1993-03-18	1994-03-14	Composes bloquant les vannes a potassium et leur utilisation

Publications (2)

Publication Number	Publication Date
EP0689450A1 EP0689450A1 (fr)	1996-01-03
EP0689450A4 true EP0689450A4 (fr)	1997-05-21

Family

ID=21870134

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP94911588A Withdrawn EP0689450A4 (fr)	1993-03-18	1994-03-14	Composes bloquant les vannes a potassium et leur utilisation

Country Status (6)

Country	Link
EP (1)	EP0689450A4 (fr)
JP (1)	JPH08508250A (fr)
CN (1)	CN1125402A (fr)
AU (1)	AU6407594A (fr)
CA (1)	CA2158051A1 (fr)
WO (1)	WO1994021278A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60112424T2 (de) *	2000-05-10	2006-05-24	Centre National De La Recherche Scientifique (Cnrs)	Protonen-abhängiges na+-kanal hemmendes polypeptid
AU2003275128A1 (en)	2002-09-23	2004-04-08	E. I. Du Pont De Nemours And Company	Isolation and use of ryanodine receptors
BRPI0605484A8 (pt) *	2006-11-21	2017-03-07	Fund Amparo Pesquisa Estado Minas Gerais Fapemig	Toxina ph(alfa)1b, cdna do gene da toxina ph(alfa)1b, composições farmacêuticas contendo a toxina ph(alfa)1b, processo para sua obtenção, processo para obtenção do cdna, e produto
CN106146639B (zh) *	2015-04-21	2019-05-03	湖南师范大学	一种来源于雷氏大疣蛛毒液的钾离子通道抑制剂
WO2019075459A1 (fr)	2017-10-13	2019-04-18	Mayo Foundation For Medical Education And Research	Procédés et dispositifs d'électroporation pour le traitement d'une fibrillation ventriculaire

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4925664A (en) *	1986-10-20	1990-05-15	University Of Utah	Spider toxins and methods for their use as blockers of calcium channels and amino acid receptor function
WO1994010195A1 (fr) *	1992-10-30	1994-05-11	Pfizer Inc.	Polypeptides provenant du venin de l'heteropoda venatoria et bloquant les canaux calciques

1994
- 1994-03-14 CA CA002158051A patent/CA2158051A1/fr not_active Abandoned
- 1994-03-14 CN CN94192030A patent/CN1125402A/zh active Pending
- 1994-03-14 JP JP6521163A patent/JPH08508250A/ja active Pending
- 1994-03-14 EP EP94911588A patent/EP0689450A4/fr not_active Withdrawn
- 1994-03-14 AU AU64075/94A patent/AU6407594A/en not_active Abandoned
- 1994-03-14 WO PCT/US1994/002750 patent/WO1994021278A1/fr not_active Application Discontinuation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4925664A (en) *	1986-10-20	1990-05-15	University Of Utah	Spider toxins and methods for their use as blockers of calcium channels and amino acid receptor function
WO1994010195A1 (fr) *	1992-10-30	1994-05-11	Pfizer Inc.	Polypeptides provenant du venin de l'heteropoda venatoria et bloquant les canaux calciques

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LAVRETSKY E.ET AL.: "A group of Potassium-Channel Blockers-Acetylcholine Releasers: New Potentials for Alzheimer Disease? A Reviewse", JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, vol. 12, no. 2, April 1992 (1992-04-01), pages 110 - 118, XP000647340 *
See also references of WO9421278A1 *

Also Published As

Publication number	Publication date
CA2158051A1 (fr)	1994-09-29
AU6407594A (en)	1994-10-11
JPH08508250A (ja)	1996-09-03
WO1994021278A1 (fr)	1994-09-29
CN1125402A (zh)	1996-06-26
EP0689450A1 (fr)	1996-01-03

Publication	Publication Date	Title
EG20459A (en)	1999-04-29	Absorbent compositif
GB9422158D0 (en)	1994-12-21	N-acylindoles and related compounds
GB2298422B (en)	1997-01-29	Compounds and their use
DE69417650D1 (en)	1999-05-12	Orthodontisches band
HU9402884D0 (en)	1995-01-30	4-arylamino-benzopyran and related compounds
EP0734398A4 (fr)	1997-04-16	Composes et procedes
GB9411045D0 (en)	1994-07-20	Compounds and use
AU4758997A (en)	1998-05-11	Potassium channel blocking compounds and their use
EP0689450A4 (fr)	1997-05-21	Composes bloquant les vannes a potassium et leur utilisation
HU9402155D0 (en)	1994-09-28	Azin-derivatives and insekticidal composition containing them
AU1292995A (en)	1995-06-13	Bis-oxazolidine compounds and their use
GB9314919D0 (en)	1993-09-01	Bleending tape
GB9501907D0 (en)	1995-03-22	Allatostatins and their use
GB9314512D0 (en)	1993-08-25	Composition and use
GB9306456D0 (en)	1993-05-19	Composition and use
GB9408859D0 (en)	1994-06-22	Composition and use
ZA942736B (en)	1994-10-24	Compounds and use
GB9311223D0 (en)	1993-07-21	Compounds and use
GB9303913D0 (en)	1993-04-14	Compound and use
AU120381S (en)	1994-05-18	Channel section
GB9403333D0 (en)	1994-04-13	Compound and use
GB2451221B (en)	2009-07-22	Azidoalkylformals, their prepararion and use
GB9214371D0 (en)	1992-08-19	Compound and use
GB9325621D0 (en)	1994-02-16	Compounds and methods
GB9302343D0 (en)	1993-03-24	Compounds and methods

Legal Events

Date	Code	Title	Description
1995-11-17	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1996-01-03	17P	Request for examination filed	Effective date: 19951018
1996-01-03	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1997-05-21	A4	Supplementary search report drawn up and despatched	Effective date: 19970407
1997-05-21	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
1999-02-26	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1999-04-14	18D	Application deemed to be withdrawn	Effective date: 19981001