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EP0212407B1 - Self-decontaminating detergent - Google Patents

Self-decontaminating detergent Download PDF

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Publication number
EP0212407B1
EP0212407B1 EP86110724A EP86110724A EP0212407B1 EP 0212407 B1 EP0212407 B1 EP 0212407B1 EP 86110724 A EP86110724 A EP 86110724A EP 86110724 A EP86110724 A EP 86110724A EP 0212407 B1 EP0212407 B1 EP 0212407B1
Authority
EP
European Patent Office
Prior art keywords
weight
cleansing
fatty acid
concentrates
hydrogen peroxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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EP86110724A
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German (de)
French (fr)
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EP0212407A3 (en
EP0212407A2 (en
Inventor
Klaus Dr. Hachmann
Karlheinz Dr. Disch
Klaus Dr. Bansemir
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Henkel AG and Co KGaA
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Henkel AG and Co KGaA
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Priority to AT86110724T priority Critical patent/ATE58915T1/en
Publication of EP0212407A2 publication Critical patent/EP0212407A2/en
Publication of EP0212407A3 publication Critical patent/EP0212407A3/en
Application granted granted Critical
Publication of EP0212407B1 publication Critical patent/EP0212407B1/en
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/39—Organic or inorganic per-compounds
    • C11D3/3942—Inorganic per-compounds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/39—Organic or inorganic per-compounds
    • C11D3/3947—Liquid compositions

Definitions

  • Water-miscible concentrates with a high content of surfactants are ideal breeding grounds for microorganisms, so that these products must be protected from attack and decomposition by microorganisms - in particular bacteria, fungi and spore formers. The undesired entry of such microorganisms can occur, for example, during the manufacture or use of the product. It is common practice to protect cleaning agents or corresponding concentrates of the type described by means of preservatives, a limited number of preservatives being available through the Cosmetics Regulation.
  • Hand wash lotions are not subject to the Medicines Act. However, they have to meet special requirements when used in particular in the medical field, i.e. in the hospital, in the doctor's office or in general in nursing. In the applications described here, there is an increased risk of contamination of the water-miscible lotions with pathogenic microorganisms and spore formers. Accordingly, the corresponding cleaning agents should have the ability to automatically eliminate any germs that may occur. This is not possible with the usual preservatives, which only show microbistatic, but no microbicidal, effects in the approved use concentrations.
  • US-A 3 440 319 describes an aqueous germicidal composition which contains a halogenated germicidal active ingredient and either hydrogen peroxide alone or a combination of hydrogen peroxide and a water-soluble inorganic sulfite as a discoloration inhibitor.
  • Anionic, cationic or non-ionic surfactants e.g. Fatty acid alkanolamides can be present.
  • no content of salts such as ammonium sulfate, sodium chloride, potassium chloride, sodium sulfate or potassium citrate is mentioned.
  • US Pat. No. 3,833,565 describes, in connection with the active ingredient phenylantimony-bis (2-pyridinthiol-1-oxide), antimicrobial compositions which contain fatty acid alkanolamides.
  • the invention is based on the object of providing surfactant-containing thickened cleaning agents and, in particular, cleaning agent concentrates which, through the use of small amounts of hydrogen peroxide, have the ability to sterilize themselves, but nevertheless correspond in physical appearance to the desired viscose-thickened compositions.
  • the solution to this problem according to the invention is based on the finding that the joint use of hydrogen peroxide with the combination of fatty acid alkanolamides and inorganic salts described below leads to the desired property profile.
  • the viscosities of the washing lotions containing hydrogen peroxide can be adjusted to the range of up to 5000 mPas, which is particularly desirable in practice, and in particular from 500 to 4000 mPas (Brookfield, as previously determined).
  • the fatty acid alkanolamides are derived in particular from fatty acids in the C number range from about 10 to 22, in particular in the range from 12 to 18.
  • the fatty acids can be saturated, but also partially olefinically unsaturated.
  • Fatty acid alkanolamide mixtures which are derived on the one hand from coconut fatty acids and on the other hand from oleic acid.
  • Fatty acid dialkanolamides and especially fatty acid diethanolamides are the mixture components preferred according to the invention for viscosity control.
  • Combinations of coconut fatty acid diethanolamide and oleic acid diethanolamide in mixing ratios in the range from 0.2 to 5: 1 are particularly suitable.
  • the detergent concentrates contain the hydrogen peroxide in amounts of 0.05 to a maximum of 2 percent by weight, based on the total weight of the detergent concentrate, preferably hydrogen peroxide in amounts of 0.1 to 1.5 percent by weight and in particular in amounts of 0.2 to 1 percent by weight.
  • preservatives can be present in accordance with Annex VI of the EC Cosmetics Directive. Examples include esters of p-hydroxybenzoic acid, bromo-5-nitro-1,3-dioxane, 2,4,4'-trichloro-2-hydroxydiphenyl ether, chlorhexidine, phenol derivatives and aldehydes.
  • the mixing ratio of such preservatives deviating from H 2 0 2 to hydrogen peroxide is preferably in the range from 0 to 2: 1.
  • the cleaning agent concentrates can contain other usual mixture components, such as refatting agents, e.g. Glycerol EO fatty acid esters, fatty alcohol polyalkylene ethers, polyol fatty acid esters, wax esters, pearlescent agents, e.g. Contain fatty acid monoethanoiamide, fatty alcohol ether sulfates, fragrances and / or dyes.
  • refatting agents e.g. Glycerol EO fatty acid esters, fatty alcohol polyalkylene ethers, polyol fatty acid esters, wax esters, pearlescent agents, e.g. Contain fatty acid monoethanoiamide, fatty alcohol ether sulfates, fragrances and / or dyes.
  • the viscosity of the cleaning agent concentrates is preferably set in the range from 500 to 4000 mPas. Assemblies of the type described show the effect of self-decontamination. They are stable in storage tests under changing climate conditions in the temperature range from 0 to 40 ° C.

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

A microbially self-decontaminating dermatological cleansing concentrate containing at least one washing-active surfactant and at least one standard cleansing concentrate additive, and having a viscosity of about 500 to 5,000 mPas, improved by incorporating hydrogen peroxide, at least one fatty acid alkanolamide, and at least one water soluble alkali salt or ammonium salt; and a method for its use.

Description

Wassermischbare Konzentrate mit einem hohen Gehalt an Tensiden zum Beispiel vom Typ der Handwaschlotionen stellen für Mikroorganismen ideale Nährböden dar, so daß diese Produkte vor dem Befall und der Zersetzung durch Mikroorganismen - insbesondere Bakterien, Pilze und Sporenbildner - geschützt werden müssen. Der unerwünschte Eintrag solcher Mikroorganismen kann beispielsweise bei der Herstellung oder bei der Verwendung des Produktes auftreten. Es ist übliche Praxis, Reinigungsmittel beziehungsweise entsprechende Konzentrate der geschilderten Art durch Konservierungsstoffe zu schützen, wobei eine durch die Kosmetikverordnung begrenzte Anzahl von Konservierungsstoffen zur Verfügung steht.Water-miscible concentrates with a high content of surfactants, for example of the type of hand-washing lotions, are ideal breeding grounds for microorganisms, so that these products must be protected from attack and decomposition by microorganisms - in particular bacteria, fungi and spore formers. The undesired entry of such microorganisms can occur, for example, during the manufacture or use of the product. It is common practice to protect cleaning agents or corresponding concentrates of the type described by means of preservatives, a limited number of preservatives being available through the Cosmetics Regulation.

Handwaschlotionen unterliegen nicht dem Arzneimittelgesetz. An sie müssen aber beim Einsatz insbesondere im Medizinalbereich, also im Krankenhaus, in der Arztpraxis oder allgemein bei der Krankenpflege besondere Anforderungen gestellt werden. Bei den hier geschilderten Anwendungsfällen besteht die erhöhte Gefahr einer Kontamination der wassermischbaren Lotionen mit pathogenen Mikroorganismen und Sporenbildnern. Die entsprechenden Reinigungsmittel sollten dementsprechend die Fähigkeit besitzen, eventuell auftretende Verkeimungen selbsttätig zu eliminieren. Das ist mit den gebräuchlichen Konservierungsmitteln, die in den zugelassenen Einsatzkonzentrationen nur mikrobistatische, jedoch keine mikrobizide Wirkung zeigen, nicht möglich.Hand wash lotions are not subject to the Medicines Act. However, they have to meet special requirements when used in particular in the medical field, i.e. in the hospital, in the doctor's office or in general in nursing. In the applications described here, there is an increased risk of contamination of the water-miscible lotions with pathogenic microorganisms and spore formers. Accordingly, the corresponding cleaning agents should have the ability to automatically eliminate any germs that may occur. This is not possible with the usual preservatives, which only show microbistatic, but no microbicidal, effects in the approved use concentrations.

Zur Entwicklung autosteriler Reinigungsmittel beispielsweise von der Art der Handwaschlotionen für den Medizinalbereich muß dementsprechend nach Möglichkeiten gesucht werden, durch Zusatz geringer Mengen an toxikologisch - insbesondere dermatologisch - unbedenklicher Substanzen neben der bereits durch den Zusatz von Konservierungsstoffen erreichten Haltbarmachung eine mikrobizide Wirkung zu erreichen.For the development of autosterile cleaning agents, for example of the type of hand-washing lotions for the medical sector, it is accordingly necessary to look for ways of achieving a microbicidal effect by adding small amounts of toxicologically - in particular dermatologically - harmless substances in addition to the preservation already achieved by the addition of preservatives.

Es ist bekannt, daß man durch Zugabe geringer Mengen von Wasserstoffperoxid zu wässrigen Desinfektionsmitteln selbstdekontaminierende Hautdesinfektionsmittel gewinnen kann. So schildert die DE-OS 29 04 217 Desinfektionsmittel auf Basis von wässrigen Alkohollösungen, die zusätzlich geringe Mengen von Wasserstoffperoxid enthalten. Desinfektionsmittel dieser Art sind in der Lage, unfreiwillig eingebrachte Sporen abzutöten und damit das Desinfektionsmittel im Gebrauch keimfrei zu halten.It is known that self-decontaminating skin disinfectants can be obtained by adding small amounts of hydrogen peroxide to aqueous disinfectants. DE-OS 29 04 217 describes disinfectants based on aqueous alcohol solutions which additionally contain small amounts of hydrogen peroxide. Disinfectants of this type are able to kill spores that have been involuntarily introduced and thus keep the disinfectant germ-free during use.

Gemäß der heutigen Praxis ist es allerdings üblich, zur Verbesserung der Haptik und der Handhabung von Reinigungsmitteln der beschriebenen Art und insbesondere von Handwaschlotionen diese durch den Einsatz von organischen Verdickungsmitteln auf Viskositäten etwa im Bereich von 500 bis 5000 mPas, insbesondere auf Viskositäten im Bereich von etwa 500 bis 4000 mPas - gemessen z.B. mit einem Rotationsviskosimeter der Fa. Brookfield, Modell LVF, bei 20° C, Spindel 4/20 Upmin - einzustellen. Der Zusatz von Wasserstoffperoxid zu solchen eingedickten tensidhaltigen Reinigungsmitteikonzentraten bringt erhebliche Konfektionierungsprobleme, da schon durch den Zusatz geringer Mengen an Wasserstoffperoxid die viskositätsregulierenden Eigenschaften der herkömmlichen Verdicker verloren gehen.According to current practice, however, it is customary to improve the feel and handling of cleaning agents of the type described and in particular hand wash lotions by using organic thickeners to viscosities in the range from about 500 to 5000 mPas, in particular to viscosities in the range of about 500 to 4000 mPas - measured, for example, using a Brookfield rotary viscometer, model LVF, at 20 ° C., spindle 4/20 rpm. The addition of hydrogen peroxide to such thickened surfactant-containing cleaning agent concentrates poses considerable packaging problems, since the addition of small amounts of hydrogen peroxide loses the viscosity-regulating properties of the conventional thickeners.

In der US-A 4 130 501 werden wäßrige Wasserstoffperoxidlösungen beschrieben, die neben einem vernetzten Polymeren als Verdickungsmittel Fettsäuremono- und -diethanolamide als oberflachenaktive Substanzen enthalten. Die Viskosität dieser Zusammensetzungen ist bei der Lagerung nicht stabil.US Pat. No. 4,130,501 describes aqueous hydrogen peroxide solutions which, in addition to a crosslinked polymer as a thickening agent, contain fatty acid mono- and diethanolamides as surface-active substances. The viscosity of these compositions is not stable during storage.

Die US-A 3 440 319 beschreibt eine wäßrige keimtötende Zusammensetzung, die einen halogenierten keimtötenden Wirkstoff und entweder Wasserstoffperoxid allein oder eine Kombination aus Wasserstoffperoxid und einem wasserlöslichen anorganischen Sulfit als Verfärbungsinhibitor enthält. Anionische, kationische oder nichtionogene Tenside, wie z.B. Fettsäurealkanolamide können vorhanden sein. In dieser Druckschrift wird kein Gehalt an Salzen wie Ammoniumsulfat, Natriumchlorid, Kaliumchlorid, Natriumsulfat oder Kaliumzitrat erwähnt.US-A 3 440 319 describes an aqueous germicidal composition which contains a halogenated germicidal active ingredient and either hydrogen peroxide alone or a combination of hydrogen peroxide and a water-soluble inorganic sulfite as a discoloration inhibitor. Anionic, cationic or non-ionic surfactants, e.g. Fatty acid alkanolamides can be present. In this document, no content of salts such as ammonium sulfate, sodium chloride, potassium chloride, sodium sulfate or potassium citrate is mentioned.

Die US-A 3 833 565 beschreibt im Zusammenhang mit dem Wirkstoff Phenylantimon-bis(2-pyridinthiol-1-oxid) antimikrobiell wirksame Zusammensetzungen, die Fettsäurealkanolamide enthalten.US Pat. No. 3,833,565 describes, in connection with the active ingredient phenylantimony-bis (2-pyridinthiol-1-oxide), antimicrobial compositions which contain fatty acid alkanolamides.

Die Erfindung geht von der Aufgabe aus, tensidhaltige eingedickte Reinigungsmittel und insbesondere Reinigungsmittelkonzantrate zur Verfügung zu stellen, die durch Mitverwendung geringer Mengen an Wasserstoffperoxid die Fähigkeit zur selbsttätigen Sterilisation besitzen, in ihrem physikalischen Erscheinungsbild gleichwohl den gewünschten viskos angedickten Massen entsprechen.The invention is based on the object of providing surfactant-containing thickened cleaning agents and, in particular, cleaning agent concentrates which, through the use of small amounts of hydrogen peroxide, have the ability to sterilize themselves, but nevertheless correspond in physical appearance to the desired viscose-thickened compositions.

Die Lösung dieser erfindungsgemäßen Aufgabenstellung geht von der Feststellung aus, daß die gemeinsame Verwendung von Wasserstoffperoxid mit der im folgenden geschilderten Kombination von Fettsäurealkanolamiden und anorganischen Salzen zum gewünschten Eigenschaftsbild führt.The solution to this problem according to the invention is based on the finding that the joint use of hydrogen peroxide with the combination of fatty acid alkanolamides and inorganic salts described below leads to the desired property profile.

Gegenstand der Erfindung sind dementsprechend angedickte wassermischbare und autosterile Reinigungsmittelkonzentrate, insbesondere für den Einsatz als Handwaschlotion im Medizinalbereich, mit einer Viskosität im Bereich von 500 bis 5000 mPas, gemessen mit einem Rotationsviskosimeter der Fa. Brookfield, Modell LVF, Spindel 4/20 Upmin, bei 20°C, enthaltend 5 bis 15 Gewichtsprozent waschaktive Tenside, ausgewählt aus der aus Alkylethersulfaten, Amidethersulfaten, Sulfobernsteinsäureestern und Eiweiß-Fettsäure-Kondensaten bestehenden Gruppe, in Form ihrer Na-, (NH4)- oder Ethanolamin-Salze, dermatologisch verträgliche Desinfektions- und/oder Konservierungsmittel sowie gewünschtenfalls übliche Zusatzstoffe wie Rückfetter, Perlglanzmitel, Duftstoffe und Farbstoffe. Dise Reinigungsmittelkonzentrate sind dadurch gekennzeichnet, daß sie zusammen mit 0,05 bis 2 Gewichtsprozent Wasserstoffperoxid als Eindickungsmittel eine Kombination aus

  • A) 0,2 bis 5 Gewichtsprozent Fettsäurealkanolamiden, und
  • B) 0,5 bis 3 Gewichtsprozent wasserlöslichen, nicht-korrosiven Salzen ausgewählt aus der aus Ammoniumsulfat, Natriumchlorid, Kaliumchlorid, Natriumsulfat und Kaliumcitrat bestehenden Gruppe
    enthalten, wobei die Gewichtsprozentangaben jeweils auf das Gesamtgewicht des Reinigungsmittelkonzentrates bezogen sind.
The invention accordingly relates to thickened water-miscible and autosterile cleaning agent concentrates, in particular for use as hand-washing lotion in the medical field, with a viscosity in the range from 500 to 5000 mPas, measured using a Brookfield rotary viscometer, model LVF, spindle 4/20 rpm, at 20 ° C, containing 5 to 15 percent by weight of detersive surfactants selected from the group consisting of alkyl ether sulfates, amide ether sulfates, sulfosuccinic acid esters and protein fatty acid condensates, in the form of their Na, (NH 4 ) or ethanolamine salts, dermatologically compatible disinfectant and / or preservatives and, if desired, customary additives such as refatting agents, pearlescent agents, fragrances and dyes. Dise cleaning Medium concentrates are characterized in that, together with 0.05 to 2 percent by weight hydrogen peroxide as a thickener, they are a combination of
  • A) 0.2 to 5 percent by weight of fatty acid alkanolamides, and
  • B) 0.5 to 3 percent by weight of water-soluble, non-corrosive salts selected from the group consisting of ammonium sulfate, sodium chloride, potassium chloride, sodium sulfate and potassium citrate
    included, the weight percentages are based in each case on the total weight of the detergent concentrate.

Erfindungsgemäß gelingt mit dieser neuen Möglichkeit der Viskositätsregelung die Einstellung von Viskositäten der Wasserstoffperoxid enthaltenden Waschlotionen auf den in der Praxis besonders gewünschten Bereich bis 5000 mPas und insbesondere von 500 bis 4000 mPas (Brookfield, wie zuvor bestimmt).According to the invention, with this new possibility of viscosity control, the viscosities of the washing lotions containing hydrogen peroxide can be adjusted to the range of up to 5000 mPas, which is particularly desirable in practice, and in particular from 500 to 4000 mPas (Brookfield, as previously determined).

Die Fettsäurealkanolamide leiten sich insbesondere von Fettsäuren des C-Zahlbereichs von etwa 10 bis 22 insbesondere des Bereichs von 12 bis 18 ab. Die Fettsäuren können dabei gesättigt, anteilsweise aber auch olefinisch ungesättigt sein. Besonders geeignet sind z.B. Fettsäurealkanolamidgemische, die sich einerseits von Kokosfettsäuren und andererseits von Ölsäure ableiten.The fatty acid alkanolamides are derived in particular from fatty acids in the C number range from about 10 to 22, in particular in the range from 12 to 18. The fatty acids can be saturated, but also partially olefinically unsaturated. For example, Fatty acid alkanolamide mixtures, which are derived on the one hand from coconut fatty acids and on the other hand from oleic acid.

Fettsäuredialkanolamide und insbesondere Fettsäurediethanolamide sind die erfindungsgemäß bevorzugten Mischungskomponenten zur Viskositätsregelung. Geeignet sind insbesondere Kombinationen von Kokosfettsäurediethanolamid und Ölsäurediethanolamid in Mischungsverhältnissen im Bereich von 0,2 bis 5:1.Fatty acid dialkanolamides and especially fatty acid diethanolamides are the mixture components preferred according to the invention for viscosity control. Combinations of coconut fatty acid diethanolamide and oleic acid diethanolamide in mixing ratios in the range from 0.2 to 5: 1 are particularly suitable.

Die Reinigungsmittelkonzentrate enthalten das Wasserstoffperoxid in Mengen von 0,05 bis maximal 2 Gewichtsprozent - bezogen auf das Gesamtgewicht des Reinigungsmittelkonzentrats - wobei bevorzugt Wasserstoffperoxid in Mengen von 0,1 bis 1,5 Gewichtsprozent und insbesondere in Mengen von 0,2 bis 1 Gewichtsprozent vorliegt. Zusammen mit dem Wasserstoffperoxid können Konservierungsmittel entsprechend des Anhangs VI der EG-Richtlinie Kosmetik zugegen sein. Als Beispiele seien genannt Ester der p-Hydroxybenzoesäure, Brom-5-nitro-1,3-dioxan, 2,4,4'-Trichlor-2-hydroxydiphenylether, Chlorhexidin, Phenolderivate und Aldehyde.The detergent concentrates contain the hydrogen peroxide in amounts of 0.05 to a maximum of 2 percent by weight, based on the total weight of the detergent concentrate, preferably hydrogen peroxide in amounts of 0.1 to 1.5 percent by weight and in particular in amounts of 0.2 to 1 percent by weight. Together with the hydrogen peroxide, preservatives can be present in accordance with Annex VI of the EC Cosmetics Directive. Examples include esters of p-hydroxybenzoic acid, bromo-5-nitro-1,3-dioxane, 2,4,4'-trichloro-2-hydroxydiphenyl ether, chlorhexidine, phenol derivatives and aldehydes.

Bei der gemeinsamen Verwendung von Wasserstoffperoxid und Konservierungsmitteln liegt das Mischungsverhältnis solcher von H202 abweichender Konservierungsmittel zum Wasserstoffperoxid vorzugsweise im Mengenbereich von 0 bis 2:1.When hydrogen peroxide and preservatives are used together, the mixing ratio of such preservatives deviating from H 2 0 2 to hydrogen peroxide is preferably in the range from 0 to 2: 1.

Neben den bisher genannten Komponenten können die Reinigungsmittelkonzentrate übliche sonstige Mischungsbestandteile, wie Rückfetter, z.B. Glycerin-EO-Fettsäure-Ester, Fettalkohol-polyalkylenether, Polyol-Fettsäure-Ester, Wachsester, Perlglanzmittel, z.B. Fettsäuremonoethanoiamid, Fettalkoholethersulfate, Duftstoffe und/oder Farbstoffe enthalten.In addition to the components mentioned so far, the cleaning agent concentrates can contain other usual mixture components, such as refatting agents, e.g. Glycerol EO fatty acid esters, fatty alcohol polyalkylene ethers, polyol fatty acid esters, wax esters, pearlescent agents, e.g. Contain fatty acid monoethanoiamide, fatty alcohol ether sulfates, fragrances and / or dyes.

Besonders geeignete Reinigungsmittelkonzentrate der erfindungsgemäßen Art enthalten in wäßriger und/oder wasserlöslich organischer Lösung bzw. Aufschlemmung die folgenden Komponenten in den folgenden Mengenbereichen - Gewichtsprozent jeweils wieder bezogen auf das Gesamtgewicht des Reinigungsmittelkonzentrats:

  • 5 bis 15 Gewichtsprozent waschaktiver Tenside
  • 0,2 bis 1 Gewichtsprozent Wasserstoffperoxid, gewünschtenfalls in Gemisch mit üblichen Konservierungs- und/oder Desinfektionsmitteln
  • 0,5 bis 3,5 Gewichtsprozent der Fettsäurealkanolamide, insbesondere eine Kombination von Kokosfettsäurediethanolamid und Ölsäurediethanolamid im Verhältnis von 0,2 bis 5:1
  • 0,8 bis 2,5 Prozent der Alkali- und/oder Ammoniumsalze
  • 0,5 bis 5 Gewichtsprozent übliche Zusatzstoffe wie Rückfetter, Perlglanzmittel, Duft- und Farbstoffe.
Particularly suitable detergent concentrates of the type according to the invention contain the following components in aqueous and / or water-soluble organic solution or slurry in the following quantitative ranges - percent by weight in each case based on the total weight of the detergent concentrate:
  • 5 to 15 percent by weight of detergent surfactants
  • 0.2 to 1 percent by weight of hydrogen peroxide, if desired in a mixture with conventional preservatives and / or disinfectants
  • 0.5 to 3.5 percent by weight of the fatty acid alkanolamides, in particular a combination of coconut fatty acid diethanolamide and oleic acid diethanolamide in a ratio of 0.2 to 5: 1
  • 0.8 to 2.5 percent of the alkali and / or ammonium salts
  • 0.5 to 5 percent by weight of common additives such as refatting agents, pearlescent agents, fragrances and colorants.

Die Viskosität der Reinigungsmittelkonzentrate ist bevorzugt auf den Bereich von 500 bis 4000 mPas eingestellt. Konfektionierungen der geschilderten Art zeigen den Effekt der Selbstdekontamination. Sie sind bei Lagerversuchen unter Wechselklimabedingungen im Temperaturbereich von 0 bis 40°C stabil.The viscosity of the cleaning agent concentrates is preferably set in the range from 500 to 4000 mPas. Assemblies of the type described show the effect of self-decontamination. They are stable in storage tests under changing climate conditions in the temperature range from 0 to 40 ° C.

Beispiel:Example:

Es wurde eine Handwaschlotion (Lotion A) der folgenden Zusammensetzung hergestellt:

  • 6 Gew.-% Natriumsalz eines C,4-Fettalkoholethersulfats mit 4 EO
  • 3 Gew.-% handelsübliches Triethanolaminsalz eines Kondensationsproduktes aus Eiweißhydrolysat und Fettsäure (Lamepon(R) ST 40; Hersteller: Chemische Fabrik Grünau, Illertissen)
  • 1 Gew.-% Cu6-Fettsäuremonoethanolamid
  • 2 Gew.-% Anlagerungsprodukt von 8 EO an Glycerin, verestert mit 3 Mol Kokosfettsäure
  • 1 Gew.-% Propylenglykol
  • 2 Gew.-% Ammoniumsulfat
  • 1 Gew.-% Kokosfettsäurediethanolamid
  • 1 Gew.-% Ölsäurediethanolamid
  • 0,2 Gew.-% β-Hydroxybenzoesäuremethylester
  • 0,2 Gew.-% Wasserstoffperoxid
  • ad 100 Gew.-% Duftstoffe, Farbstoffe, Wasser
A hand wash lotion (Lotion A) with the following composition was produced:
  • 6% by weight sodium salt of a C, 4-fatty alcohol ether sulfate with 4 EO
  • 3% by weight of commercially available triethanolamine salt of a condensation product of protein hydrolyzate and fatty acid (Lamepon ( R ) ST 40; manufacturer: Chemische Fabrik Grünau, Illertissen)
  • 1% by weight of Cu6 fatty acid monoethanolamide
  • 2% by weight adduct of 8 EO on glycerol, esterified with 3 moles of coconut fatty acid
  • 1% by weight propylene glycol
  • 2% by weight ammonium sulfate
  • 1% by weight of coconut fatty acid diethanolamide
  • 1% by weight oleic acid diethanolamide
  • 0.2 wt .-% methyl β-hydroxybenzoate
  • 0.2% by weight of hydrogen peroxide
  • ad 100% by weight of fragrances, dyes, water

Zu Vergleichszwecken wurde eine Handwaschlotion derselben Zusammensetzung, jedoch ohne den Zusatz von 0,2 Gew.-% Wasserstoffperoxid hergestellt (Lotion B).For comparison purposes, a hand wash lotion of the same composition, but without the addition of 0.2% by weight of hydrogen peroxide, was produced (Lotion B).

Proben dieser Lotionen wurden mit den in der nachstehenden Tabelle angegebenen Keimen massiv kontaminiert und das mikrobiologische Verhalten der Lotionen bei der Lagerung festgestellt.Samples of these lotions were heavily contaminated with the germs listed in the table below and the microbiological behavior of the lotions during storage was determined.

Ergebnis der Auswertung:Result of the evaluation:

Ergebnis der Auswertung:Result of the evaluation:

Figure imgb0001
Figure imgb0001

Damit steht also die Möglichkeit zur Verfügung, nach Bakterien-, Pilz- oder Sporen-Befall viskositätsstabile Handwaschlotionen herzustellen, die sich selbst dekontaminieren.This means that, after bacterial, fungal or spore infestation, viscosity-stable hand-washing lotions are available that decontaminate themselves.

Claims (6)

1. Thickened, water-miscible and autosterile cleansing concentrates, more particularly for use as handwashing lotions in the medical field, having a viscosity in the range from 500 to 5,000 mPas, as measured with a Brookfield LVF rotational viscosimeter, spindle 4/20 r.p.m. at 20°C, and containing 5 to 15% by weight washing-active surfactants, selected from the group consisting of alkyl ether sulfates, amide ether sulfates, sulfosuccinic acid esters and protein/ fatty acid condensates, in the form of their sodium, (NH4) and ethanolamine salts dermatologically safe disinfectants and/or preservatives and, optionally, typical additives such as re-oiling agents, pearlescers, fragrances and dyes, characterized in that, together with 0.05 to 2% by weight hydrogen peroxide, they contain as thickener a combination of
A) 0.2 to 5% by weight fatty acid alkanolamides and
B) 0.5 to 3% by weight water-soluble, non-corrosive salts selected from the group consisting of ammonium sulfate, sodium chloride, potassium chloride, sodium sulfate and potassium citrate,
the percentages by weight being based on the total weight of the cleansing concentrate.
2. Cleansing concentrates as claimed in claim 1, characterized in that they contain fatty acid dialkanolamides, more especially fatty acid diethanolamides.
3. Cleansing concentrates as claimed in claims 1 and 2, characterized in that they contain 0.2 to 1% by weight of hydrogen peroxide, based on the total weight of cleansing concentrate, quantitative ratios of the preservatives to the hydrogen peroxide of from 0 to 2:1 being preferred.
4. Cleansing concentrates as claimed in claims 1 to 3, characterized in that they contain dialkanolamides of C12-18 fatty acids.
5. Cleansing concentrates as claimed in claims 1 to 4, characterized in that they are adjusted to a viscosity in the range from 500 to 4,000 mPas.
6. Cleansing concentrates as claimed in claims 1 to 5, characterized in that they contain the following constituents in an aqueous preparation:
5 to 15% by weight washing-active surfactants
0.2 to 1% by weight hydrogen peroxide,
0.5 to 3.5% by weight fatty acid alkanolamides,
0.8 to 2.5% by weight water-soluble alkali and/or ammonium salts,
0.5 to 5% by weight standard additives,
the percentages by weight being based on the total weight of the cleansing concentrate.
EP86110724A 1985-08-10 1986-08-02 Self-decontaminating detergent Expired - Lifetime EP0212407B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT86110724T ATE58915T1 (en) 1985-08-10 1986-08-02 SELF-DECONTAMINATING CLEANERS.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3528843 1985-08-10
DE19853528843 DE3528843A1 (en) 1985-08-10 1985-08-10 SELF-DECONTAMINATING DETERGENTS

Publications (3)

Publication Number Publication Date
EP0212407A2 EP0212407A2 (en) 1987-03-04
EP0212407A3 EP0212407A3 (en) 1988-09-07
EP0212407B1 true EP0212407B1 (en) 1990-12-05

Family

ID=6278290

Family Applications (1)

Application Number Title Priority Date Filing Date
EP86110724A Expired - Lifetime EP0212407B1 (en) 1985-08-10 1986-08-02 Self-decontaminating detergent

Country Status (5)

Country Link
US (1) US4746451A (en)
EP (1) EP0212407B1 (en)
JP (1) JPS6239698A (en)
AT (1) ATE58915T1 (en)
DE (2) DE3528843A1 (en)

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US4935248A (en) * 1988-07-28 1990-06-19 Albert L. Jacobs Antimicrobial veterinary compositions and methods
US5066497A (en) * 1988-07-28 1991-11-19 Albert L. Jacobs, Jr. Antimicrobial veterinary compositions and methods
ATE164390T1 (en) * 1990-09-28 1998-04-15 Procter & Gamble POLYHYDROXYFATTY ACID AMIDE SURFACTANT IN DETERGENT COMPOSITIONS CONTAINING BLEACH
DE4304066C2 (en) * 1993-02-11 1995-01-26 Beiersdorf Ag Use of high electrolyte concentrations in cosmetic cleaners
DE19623571C2 (en) * 1996-06-13 2000-06-08 Cognis Deutschland Gmbh Thickener for aqueous hydrogen peroxide solutions
US6235299B1 (en) * 1998-02-27 2001-05-22 Buckman Laboratories International Inc Potentiation of biocide activity using diethanolamide
PL332783A1 (en) * 1999-04-27 2000-11-06 Nowakowski Grzegorz Pharmaceutic preparation in the form of gel
DE10013796A1 (en) * 2000-03-20 2001-09-27 Kaercher Gmbh & Co Alfred Decontamination composition useful for treating surfaces contaminated with chemical warfare agents comprises an active agent, a neutral salt, an emulsifier and a solvent derived from natural fatty acids
FR2827768B1 (en) * 2001-07-27 2005-08-26 Oreal FOAMING COSMETIC COMPOSITION FOR BATH
US9192598B2 (en) * 2008-06-25 2015-11-24 University Of North Texas Health Science Center At Fort Worth Prevention of bacterial growth and biofilm formation by ligands that act on cannabinoidergic systems
JP4900370B2 (en) * 2008-12-01 2012-03-21 パナソニック株式会社 Steam iron

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GB962585A (en) * 1961-11-03 1964-07-01 Unilever Ltd Detergent compositions
NL128284C (en) * 1964-12-29
DE1924325A1 (en) * 1969-05-13 1970-11-19 Henkel & Cie Gmbh Clear liquid cleaning agent concentrates
US3833565A (en) * 1972-09-29 1974-09-03 Procter & Gamble Phenylantimony bis(2-pyridinethiol 1-oxide)
US4130501A (en) * 1976-09-20 1978-12-19 Fmc Corporation Stable viscous hydrogen peroxide solutions containing a surfactant and a method of preparing the same
US4321156A (en) * 1977-03-30 1982-03-23 S. C. Johnson & Son, Inc. Shampoo composition
CA1146851A (en) * 1978-05-01 1983-05-24 Donald F. Greene Hydrogen peroxide disinfecting and sterilizing compositions
DE2904217A1 (en) * 1979-02-05 1980-08-14 Henkel Kgaa DISINFECTANTS BASED ON ALCOHOLS AND ITS USE FOR SKIN DISINFECTION
US4329334A (en) * 1980-11-10 1982-05-11 Colgate-Palmolive Company Anionic-amphoteric based antimicrobial shampoo
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US4387040A (en) * 1981-09-30 1983-06-07 Colgate-Palmolive Company Liquid toilet soap

Also Published As

Publication number Publication date
ATE58915T1 (en) 1990-12-15
DE3528843A1 (en) 1987-02-12
EP0212407A3 (en) 1988-09-07
DE3676004D1 (en) 1991-01-17
US4746451A (en) 1988-05-24
EP0212407A2 (en) 1987-03-04
JPS6239698A (en) 1987-02-20

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