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EG14045A - New derivatives of 4-amino-5-alkylsulphonyl orthoanisamides,methods of preparing them and their application as psychotropic agents - Google Patents

New derivatives of 4-amino-5-alkylsulphonyl orthoanisamides,methods of preparing them and their application as psychotropic agents

Info

Publication number
EG14045A
EG14045A EG29/79A EG2979A EG14045A EG 14045 A EG14045 A EG 14045A EG 29/79 A EG29/79 A EG 29/79A EG 2979 A EG2979 A EG 2979A EG 14045 A EG14045 A EG 14045A
Authority
EG
Egypt
Prior art keywords
orthoanisamides
alkylsulphonyl
amino
preparing
methods
Prior art date
Application number
EG29/79A
Other languages
English (en)
Inventor
Michel Thominet
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Application granted granted Critical
Publication of EG14045A publication Critical patent/EG14045A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
EG29/79A 1978-01-20 1979-01-17 New derivatives of 4-amino-5-alkylsulphonyl orthoanisamides,methods of preparing them and their application as psychotropic agents EG14045A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7801632A FR2415099A1 (fr) 1978-01-20 1978-01-20 Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes

Publications (1)

Publication Number Publication Date
EG14045A true EG14045A (en) 1983-09-30

Family

ID=9203689

Family Applications (1)

Application Number Title Priority Date Filing Date
EG29/79A EG14045A (en) 1978-01-20 1979-01-17 New derivatives of 4-amino-5-alkylsulphonyl orthoanisamides,methods of preparing them and their application as psychotropic agents

Country Status (42)

Country Link
US (2) US4294828A (el)
JP (1) JPS6049192B2 (el)
AR (2) AR221354A1 (el)
AT (1) AT377977B (el)
AU (1) AU528561B2 (el)
BE (1) BE872585A (el)
BG (2) BG31497A3 (el)
CA (1) CA1101430A (el)
CH (1) CH637927A5 (el)
CS (1) CS226181B2 (el)
CY (1) CY1201A (el)
DD (1) DD141520A5 (el)
DE (1) DE2901181C2 (el)
DK (1) DK158346C (el)
EG (1) EG14045A (el)
ES (2) ES476755A1 (el)
FI (1) FI71126C (el)
FR (1) FR2415099A1 (el)
GB (2) GB2083458B (el)
GR (1) GR64431B (el)
HK (1) HK12184A (el)
HU (1) HU179793B (el)
IE (1) IE47798B1 (el)
IL (1) IL56411A (el)
IN (1) IN150226B (el)
IT (1) IT1164655B (el)
LU (1) LU80786A1 (el)
MC (1) MC1232A1 (el)
MX (2) MX7623E (el)
NL (1) NL191707C (el)
NO (1) NO151320C (el)
NZ (1) NZ189378A (el)
OA (1) OA06156A (el)
PH (2) PH15725A (el)
PL (2) PL118151B1 (el)
PT (1) PT69068A (el)
RO (2) RO80311A (el)
SE (2) SE448874B (el)
SU (1) SU820659A3 (el)
YU (2) YU42172B (el)
ZA (1) ZA79219B (el)
ZM (1) ZM579A1 (el)

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FR2440946A2 (fr) * 1978-01-20 1980-06-06 Ile De France Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement
NZ199080A (en) * 1980-12-12 1984-07-31 Beecham Group Ltd 2-alkoxy-4-amino-5-alkylsulphonyl-n-(3beta-(8-hydrocarbyl-8-azabicyclo (3,2,1)octyl))benzamides
FR2550447B1 (fr) * 1983-08-10 1986-01-17 Ile De France Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire
FR2574795B1 (fr) * 1984-12-18 1987-11-20 Ile De France Nouveau procede industriel de synthese du n-((1'-allyl 2'-pyrrolidinyl) methyl) 2-methoxy 4,5-azimido benzamide
FR2584401B1 (fr) * 1985-07-04 1987-11-20 Ile De France Nouveau benzamide, son procede de preparation et son application dans le domaine therapeutique
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5227388A (en) * 1989-12-26 1993-07-13 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
FR2678266A1 (fr) * 1991-06-28 1992-12-31 Delagrange Laboratoires Nouveaux derives de 2-hydroxy 4-amino 5-ethylsulfonyl benzamide utiles comme anxiolytiques.
FR2699533A1 (fr) * 1992-12-21 1994-06-24 Mouhtaram Mohamed Dérivés de N-((1,4-dialkyl-6-arylpipérazine-2-yl)méthyl)benzamides. (Isomères cis et trans) Propriétés pharmacologiques et applications.
FR2753376B1 (fr) * 1996-09-18 1998-10-16 Synthelabo Compositions pharmaceutiques comprenant de l'amisulpride et leurs applications therapeutiques
FR2762213B1 (fr) * 1997-04-18 1999-05-14 Synthelabo Composition pharmaceutique a retention gastrique
US6169094B1 (en) * 1998-07-14 2001-01-02 Sanofi-Synthelabo Compositions of (S) (-)-amisulpride
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
AU2004237951A1 (en) * 2003-05-16 2004-11-25 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with GABA modulators, anticonvulsants or benzodiazapines
FR2857263B1 (fr) * 2003-07-09 2005-09-09 Sanofi Synthelabo Nouvelle composition pharmaceutique solide comprenant de l'amisulpride
CA2565996A1 (en) * 2004-05-11 2005-11-17 Pfizer Products Inc. Combination of atypical antipsychotics and 5-ht1b receptor antagonists
TW200716091A (en) * 2005-04-22 2007-05-01 Wyeth Corp New therapeutic combinations for the treatment or prevention of psychotic disorders
CA2608144C (en) 2005-04-28 2012-11-13 Proteus Biomedical, Inc. Pharma-informatics system
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
US7825156B2 (en) * 2007-02-02 2010-11-02 Copharms Method of treating bipolar depression with a benzamide derivative
JP2011526881A (ja) * 2008-06-25 2011-10-20 ファイザー・インク ジアリール化合物およびそれらの使用
US20100105755A1 (en) * 2008-09-12 2010-04-29 Auspex Pharmaceuticals, Inc. Substituted benzamide modulators of dopamine receptor
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
KR20190116576A (ko) 2009-05-06 2019-10-14 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
CN101898991B (zh) * 2009-05-31 2013-09-25 江苏天士力帝益药业有限公司 一种(s)(-)-氨磺必利d-(-)-酒石酸盐的合成方法
CN101628886B (zh) * 2009-08-25 2012-12-12 北京紫萌同达科技有限公司 一种2-甲氧基-4-氨基-5-乙砜基苯甲酸的合成方法
AU2016216578B2 (en) * 2010-03-11 2017-11-23 Acacia Pharma Limited The use of amisulpride as an anti-emetic
GB201004020D0 (en) 2010-03-11 2010-04-21 Acacia Pharma Ltd New therapeutic use
AU2014202535B2 (en) * 2010-03-11 2016-05-26 Acacia Pharma Limited The use of amisulpride as an anti-emetic
MX2012014497A (es) 2010-06-17 2013-04-03 Lupin Ltd Un proceso mejorado para la preparación de amilsuprida.
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN103304453A (zh) * 2013-06-18 2013-09-18 苏州诚和医药化学有限公司 两步法合成2-甲氧基-4-氨基-5-乙砜基苯甲酸
CN103319384A (zh) * 2013-06-18 2013-09-25 苏州诚和医药化学有限公司 制备2-甲氧基-4-氨基-5-乙砜基苯甲酸的方法
CN103450058B (zh) * 2013-09-18 2015-10-14 广安凯特医药化工有限公司 一种氨磺必利酸的制备方法
CN104725292B (zh) * 2015-03-23 2017-07-25 湖北荆江源制药股份有限公司 一种(s)(‑)‑氨磺必利的制备方法
GB201618425D0 (en) * 2016-11-01 2016-12-14 Acacia Pharma Ltd method
US11377421B2 (en) 2016-11-28 2022-07-05 Lb Pharmaceuticals Inc. Psychotropic agents and uses thereof
MA46901A (fr) * 2016-11-28 2019-10-02 Lb Pharmaceuticals Inc Agents psychotropes et leurs utilisations
CN106995397B (zh) * 2016-12-12 2020-01-14 河北医科大学 R-氨磺必利药用盐、制备方法、晶型及其用途
GB201702250D0 (en) 2017-02-10 2017-03-29 Acacia Pharma Ltd Method
KR20200110317A (ko) 2017-12-05 2020-09-23 선오비온 파마슈티컬스 인코포레이티드 결정형 및 이의 제조 방법
WO2019113079A1 (en) 2017-12-05 2019-06-13 Sunovion Pharmaceuticals Inc. Nonracemic mixtures and uses thereof
CN110790693A (zh) * 2018-08-02 2020-02-14 北京万全德众医药生物技术有限公司 一种(s)(-)-氨磺必利的制备方法
SG11202113266YA (en) 2019-06-04 2021-12-30 Sunovion Pharmaceuticals Inc Modified release formulations and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR2313935A1 (fr) * 1975-06-10 1977-01-07 Ile De France Nouveaux benzamides substitues, leurs derives et leur procede de preparation
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
FR2244760B1 (el) * 1973-09-25 1980-06-27 Ile De France
FR2299862B1 (fr) * 1975-02-07 1978-07-21 Ile De France Nouveau
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
IE42210B1 (en) * 1974-12-18 1980-06-18 Synthelabo 2-methoxy-benzamide derivatives

Also Published As

Publication number Publication date
CA1101430A (en) 1981-05-19
YU41278B (en) 1986-12-31
AR220574A1 (es) 1980-11-14
NO151320B (no) 1984-12-10
US4401822A (en) 1983-08-30
NL191707C (nl) 1996-04-02
DE2901181A1 (de) 1979-07-26
SE8603773D0 (sv) 1986-09-09
SE448874B (sv) 1987-03-23
OA06156A (fr) 1981-06-30
DK158346B (da) 1990-05-07
AT377977B (de) 1985-05-28
SE8603773L (sv) 1986-09-09
DK20979A (da) 1979-07-21
YU25483A (en) 1983-10-31
RO76393A (ro) 1981-03-30
GR64431B (en) 1980-03-21
IE790092L (en) 1979-07-20
GB2012765B (en) 1982-09-08
DE2901181C2 (de) 1984-07-19
PH22287A (en) 1988-07-22
HU179793B (en) 1982-12-28
NO151320C (no) 1985-04-17
SE7900380L (sv) 1979-07-21
JPS6049192B2 (ja) 1985-10-31
PL116532B1 (en) 1981-06-30
DD141520A5 (de) 1980-05-07
IT7947706A0 (it) 1979-01-18
ES476755A1 (es) 1979-06-01
ATA39879A (de) 1983-12-15
FI71126B (fi) 1986-08-14
SE460968B (sv) 1989-12-11
IL56411A (en) 1982-09-30
BG31496A3 (en) 1982-01-15
RO80311A (ro) 1982-12-06
AU528561B2 (en) 1983-05-05
YU42172B (en) 1988-06-30
CY1201A (en) 1983-12-31
CS226181B2 (en) 1984-03-19
AU4337379A (en) 1979-07-26
FI790182A (fi) 1979-07-21
MC1232A1 (fr) 1979-10-26
FR2415099B1 (el) 1981-02-20
FR2415099A1 (fr) 1979-08-17
PH15725A (en) 1983-03-18
YU5079A (en) 1983-06-30
ES477782A1 (es) 1979-09-16
NZ189378A (en) 1983-03-15
PL212899A1 (el) 1980-01-14
IL56411A0 (en) 1979-03-12
GB2083458B (en) 1983-03-09
BG31497A3 (en) 1982-01-15
JPS54145658A (en) 1979-11-14
ZA79219B (en) 1980-01-30
NO790180L (no) 1979-07-23
IN150226B (el) 1982-08-21
FI71126C (fi) 1986-11-24
BE872585A (fr) 1979-06-07
MX5793E (es) 1984-07-19
GB2083458A (en) 1982-03-24
NL191707B (nl) 1995-12-01
SU820659A3 (ru) 1981-04-07
LU80786A1 (fr) 1979-09-07
IE47798B1 (en) 1984-06-27
PL118151B1 (en) 1981-09-30
PT69068A (fr) 1979-02-01
US4294828A (en) 1981-10-13
MX7623E (es) 1990-03-27
GB2012765A (en) 1979-08-01
IT1164655B (it) 1987-04-15
AR221354A1 (es) 1981-01-30
HK12184A (en) 1984-02-24
NL7900457A (nl) 1979-07-24
CH637927A5 (fr) 1983-08-31
ZM579A1 (en) 1979-12-21
DK158346C (da) 1990-10-08

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