Nothing Special   »   [go: up one dir, main page]

EE200200315A - Kvaternaarsed ammoniumiühendid ja nende kasutamine köhavastase ainena - Google Patents

Kvaternaarsed ammoniumiühendid ja nende kasutamine köhavastase ainena

Info

Publication number
EE200200315A
EE200200315A EEP200200315A EEP200200315A EE200200315A EE 200200315 A EE200200315 A EE 200200315A EE P200200315 A EEP200200315 A EE P200200315A EE P200200315 A EEP200200315 A EE P200200315A EE 200200315 A EE200200315 A EE 200200315A
Authority
EE
Estonia
Prior art keywords
quaternary ammonium
ammonium compounds
antitussive
sup
compounds
Prior art date
Application number
EEP200200315A
Other languages
English (en)
Inventor
Siu Leung Choi Lewis
N. Beatch Gregory
P. Page Clive
Original Assignee
Ucb Farchim S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Farchim S.A. filed Critical Ucb Farchim S.A.
Publication of EE200200315A publication Critical patent/EE200200315A/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
EEP200200315A 1999-12-15 2000-12-15 Kvaternaarsed ammoniumiühendid ja nende kasutamine köhavastase ainena EE200200315A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2292343 1999-12-15
PCT/CA2000/001508 WO2001044167A1 (en) 1999-12-15 2000-12-15 Quaternary ammonium compounds and their use as anti-tussive agents

Publications (1)

Publication Number Publication Date
EE200200315A true EE200200315A (et) 2003-08-15

Family

ID=4164883

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200315A EE200200315A (et) 1999-12-15 2000-12-15 Kvaternaarsed ammoniumiühendid ja nende kasutamine köhavastase ainena

Country Status (22)

Country Link
US (2) US20030181489A1 (et)
EP (1) EP1254104B1 (et)
JP (1) JP2003517034A (et)
KR (1) KR20020092352A (et)
CN (1) CN1423630A (et)
AT (1) ATE293097T1 (et)
AU (1) AU2334701A (et)
BG (1) BG106815A (et)
BR (1) BR0016427A (et)
CZ (1) CZ20022097A3 (et)
DE (1) DE60019465D1 (et)
EE (1) EE200200315A (et)
HU (1) HUP0203918A3 (et)
IL (1) IL150181A0 (et)
IS (1) IS6416A (et)
MX (1) MXPA02006049A (et)
NO (1) NO20022868L (et)
NZ (1) NZ519747A (et)
PL (1) PL355944A1 (et)
RU (1) RU2002116212A (et)
WO (1) WO2001044167A1 (et)
ZA (1) ZA200205567B (et)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2703324A (en) * 1950-08-30 1955-03-01 Bristol Lab Inc Basic ethers of aralkyl phenols and salts thereof
US2642434A (en) * 1951-09-05 1953-06-16 Sterling Drug Inc Quaternary ammonium salts of lower alkyl 4-substituted-2-(tertiaryaminoalkoxy) benzoates and their preparation
US2913459A (en) * 1954-12-09 1959-11-17 Eprova Ltd New quaternary ammonium compounds and process for the production thereof
GB919126A (en) * 1958-07-01 1963-02-20 Wellcome Found Quaternary ammonium compounds and their preparation
GB935613A (en) * 1960-02-04 1963-08-28 Wellcome Found Quaternary ammonium compounds and their preparation
US3840666A (en) * 1972-07-05 1974-10-08 Univ Michigan Anti-arrhythmic quaternary salt compositions and methods of use
US4048335A (en) * 1974-06-17 1977-09-13 The Regents Of The University Of Michigan Method of inhibiting myocardial ischemia in mammals using quaternary salts
DE2940765A1 (de) * 1979-10-08 1981-04-23 Basf Ag, 6700 Ludwigshafen Substituierte alkylammoniumsalze, ihre herstellung, ihre verwendung zur regulierung des pflanzenwachstums und mittel dafuer
WO1999064398A1 (en) * 1998-06-09 1999-12-16 Nortran Pharmaceuticals, Inc. Quarternary ammonium compounds as anti-tussive agents

Also Published As

Publication number Publication date
EP1254104B1 (en) 2005-04-13
WO2001044167A1 (en) 2001-06-21
BG106815A (en) 2003-04-30
HUP0203918A3 (en) 2005-06-28
MXPA02006049A (es) 2004-08-23
ZA200205567B (en) 2003-10-13
BR0016427A (pt) 2002-10-29
CN1423630A (zh) 2003-06-11
NO20022868D0 (no) 2002-06-14
ATE293097T1 (de) 2005-04-15
NO20022868L (no) 2002-08-14
AU2334701A (en) 2001-06-25
IL150181A0 (en) 2002-12-01
NZ519747A (en) 2003-08-29
IS6416A (is) 2002-06-12
EP1254104A1 (en) 2002-11-06
US20050197383A1 (en) 2005-09-08
KR20020092352A (ko) 2002-12-11
JP2003517034A (ja) 2003-05-20
PL355944A1 (en) 2004-05-31
WO2001044167A8 (en) 2001-12-06
RU2002116212A (ru) 2004-02-10
HUP0203918A2 (hu) 2003-03-28
US20030181489A1 (en) 2003-09-25
CZ20022097A3 (cs) 2002-11-13
DE60019465D1 (de) 2005-05-19

Similar Documents

Publication Publication Date Title
ES2191048T3 (es) Derivados de oxazolidinona y compuestos farmaceuticos que los contienen.
ATE165830T1 (de) Dihydro pyrazolopyrrole
BG108269A (en) Pyrazolopyrimidines as therapeutic agents
BG108268A (en) Pyrazolopyrimidines as therapeutic agents
CY1106522T1 (el) Ετepοκυκλικη ενωση και αντικαρκινικο μεσο που πepιεχει την ιδια ως δραστικο συστατικο
BG106586A (en) Pyrazolopyramidines as therapeutic agents
MX9707453A (es) Derivados de quinazolina.
TR200302214T4 (tr) Psoriasis tedavisi için kullanilan pteridine bileşkenleri
SE0104250D0 (sv) Heterocyclic compounds
YU44102A (sh) Ciklična kvaternerna amonijum jedinjenja
YU44202A (sh) Kvaternerne soli n-substituisanih cikiličnih ili ne- cikličnih amina kao farmaceutski preparati
DK1811994T3 (da) Nye derivater af porphyrin, især chloriner og bacteriochloriner samt deres anvendelser ved fotodynamisk terapi
DE69330601D1 (de) Serotoninergische ergolin derivate
SE0104326D0 (sv) Therapeutic heterocycles
EE200200315A (et) Kvaternaarsed ammoniumiühendid ja nende kasutamine köhavastase ainena
DE60014915D1 (de) Hypoxanthin- und thiohypxanthin-verbindungen