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ECSP16086232A - (r) -pirlindole y sus sales farmacéuticamente aceptables para uso en medicina - Google Patents

(r) -pirlindole y sus sales farmacéuticamente aceptables para uso en medicina

Info

Publication number
ECSP16086232A
ECSP16086232A ECIEPI201686232A ECPI201686232A ECSP16086232A EC SP16086232 A ECSP16086232 A EC SP16086232A EC IEPI201686232 A ECIEPI201686232 A EC IEPI201686232A EC PI201686232 A ECPI201686232 A EC PI201686232A EC SP16086232 A ECSP16086232 A EC SP16086232A
Authority
EC
Ecuador
Prior art keywords
pirlindole
pharmaceutically acceptable
acceptable salts
medicine
pain
Prior art date
Application number
ECIEPI201686232A
Other languages
English (en)
Inventor
Pedroso Pedro Filipe Eufrasio
Pecorelli Susana Marques Almeida
Ana Sofia Da Conceicao Lopes
Caixado Carlos Alberto Eufrasio Casimiro
Filipe Augusto Eugenio Pardal
Joao Carlos Ramos Damil
Original Assignee
Tecnimede Sociedade Tecnico Medicinal S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecnimede Sociedade Tecnico Medicinal S filed Critical Tecnimede Sociedade Tecnico Medicinal S
Publication of ECSP16086232A publication Critical patent/ECSP16086232A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)

Abstract

(R)-pirlindole o sus sales farmacéuticamente aceptables, así como composiciones farmacéuticas que comprenden el mismo para uso en el tratamiento terapéutico y prevención del dolor.
ECIEPI201686232A 2014-05-09 2016-11-09 (r) -pirlindole y sus sales farmacéuticamente aceptables para uso en medicina ECSP16086232A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/PT2014/000028 WO2015171004A1 (en) 2014-05-09 2014-05-09 (r)-pirlindole and its pharmaceutically acceptable salts for use in medicine

Publications (1)

Publication Number Publication Date
ECSP16086232A true ECSP16086232A (es) 2017-02-24

Family

ID=50819930

Family Applications (1)

Application Number Title Priority Date Filing Date
ECIEPI201686232A ECSP16086232A (es) 2014-05-09 2016-11-09 (r) -pirlindole y sus sales farmacéuticamente aceptables para uso en medicina

Country Status (28)

Country Link
US (2) US20170145015A1 (es)
EP (1) EP3054950B1 (es)
JP (1) JP2017514884A (es)
KR (1) KR102232198B1 (es)
CN (1) CN106413714A (es)
AU (1) AU2014393489B2 (es)
CA (1) CA2948596C (es)
CY (1) CY1119522T1 (es)
DK (1) DK3054950T3 (es)
EC (1) ECSP16086232A (es)
ES (1) ES2649491T3 (es)
HR (1) HRP20171650T1 (es)
HU (1) HUE035030T2 (es)
IL (1) IL248854B (es)
LT (1) LT3054950T (es)
MA (1) MA39448B1 (es)
MX (1) MX368735B (es)
NO (1) NO3054950T3 (es)
NZ (1) NZ726131A (es)
PH (1) PH12016502236A1 (es)
PL (1) PL3054950T3 (es)
PT (1) PT3054950T (es)
RS (1) RS56590B1 (es)
RU (1) RU2695607C2 (es)
SI (1) SI3054950T1 (es)
TN (1) TN2016000497A1 (es)
UA (1) UA116499C2 (es)
WO (1) WO2015171004A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3831385T3 (pl) * 2014-05-09 2024-10-14 Tecnimede Sociedade Tecnico-Medicinal S.A. Sole migdalanowe enancjomerów pirlindolu do stosowania w medycynie
PT3054950T (pt) 2014-05-09 2017-11-29 Tecnimede-Sociedade Tecnico-Medicinal S A (r)-pirlindol ou seus sais farmaceuticamente aceitáveis para uso em medicina
KR102421013B1 (ko) 2016-05-19 2022-07-14 에스케이바이오팜 주식회사 삼차신경통을 예방 또는 치료하기 위한 카바메이트 화합물의 용도
US20210386365A1 (en) * 2018-06-13 2021-12-16 Children`S Medical Center Corporation Biomarkers of neuropathic pain

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1558231A4 (en) * 2002-10-03 2010-09-08 Cypress Bioscience Inc DOSAGE CLIMBING AND FRICTIONAL DAILY DOSE OF ANTIDEPRESSANTS TO TREAT NEUROLOGICAL DISORDERS
BR0317747A (pt) * 2002-12-24 2005-11-22 Neurochem Int Ltd Método de tratamento terapêutico concomitante de um indivìduo, composição farmacêutica, kit, uso de um primeiro agente e um segundo agente, e, métodos de prevenir ou tratar uma doença relacionada com amilóide-b, doença de alzheimer e insuficiência cognitiva suave
CA2538997A1 (en) * 2003-09-15 2005-03-24 Vectura Limited Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation
EP1688161A1 (en) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis
MX368734B (es) * 2014-05-09 2019-10-14 Tecnimede Sociedade Tecnico Medicinal S (s)-pirlindol o sus sales farmaceuticamente aceptables para uso en medicina.
PL3831385T3 (pl) * 2014-05-09 2024-10-14 Tecnimede Sociedade Tecnico-Medicinal S.A. Sole migdalanowe enancjomerów pirlindolu do stosowania w medycynie
PT3054950T (pt) 2014-05-09 2017-11-29 Tecnimede-Sociedade Tecnico-Medicinal S A (r)-pirlindol ou seus sais farmaceuticamente aceitáveis para uso em medicina

Also Published As

Publication number Publication date
RU2016148182A (ru) 2018-06-13
AU2014393489A1 (en) 2016-11-24
RU2695607C2 (ru) 2019-07-24
PT3054950T (pt) 2017-11-29
US20180111944A1 (en) 2018-04-26
PH12016502236A1 (en) 2017-02-06
HUE035030T2 (en) 2018-05-02
LT3054950T (lt) 2017-11-27
AU2014393489B2 (en) 2020-01-02
IL248854A0 (en) 2017-01-31
WO2015171004A1 (en) 2015-11-12
EP3054950A1 (en) 2016-08-17
CY1119522T1 (el) 2018-03-07
PL3054950T3 (pl) 2018-02-28
JP2017514884A (ja) 2017-06-08
CA2948596C (en) 2021-06-08
EP3054950B1 (en) 2017-08-02
NO3054950T3 (es) 2017-12-30
RU2016148182A3 (es) 2018-06-13
UA116499C2 (uk) 2018-03-26
KR20170003567A (ko) 2017-01-09
RS56590B1 (sr) 2018-02-28
US20170145015A1 (en) 2017-05-25
KR102232198B1 (ko) 2021-03-26
SI3054950T1 (sl) 2017-12-29
IL248854B (en) 2020-05-31
CA2948596A1 (en) 2015-11-12
NZ726131A (en) 2018-12-21
HRP20171650T1 (hr) 2017-12-15
TN2016000497A1 (en) 2018-04-04
MX2016014701A (es) 2017-05-23
MA39448A1 (fr) 2018-08-31
MX368735B (es) 2019-10-14
ES2649491T3 (es) 2018-01-12
US10533012B2 (en) 2020-01-14
DK3054950T3 (en) 2017-11-06
MA39448B1 (fr) 2019-12-31
CN106413714A (zh) 2017-02-15

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