ECSP12012097A - Derivados de fumarato de ácido graso y sus usos - Google Patents
Derivados de fumarato de ácido graso y sus usosInfo
- Publication number
- ECSP12012097A ECSP12012097A ECSP12012097A ECSP12012097A EC SP12012097 A ECSP12012097 A EC SP12012097A EC SP12012097 A ECSP12012097 A EC SP12012097A EC SP12012097 A ECSP12012097 A EC SP12012097A
- Authority
- EC
- Ecuador
- Prior art keywords
- fatty acid
- derivatives
- fumarate
- acid fumarate
- derivative
- Prior art date
Links
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 4
- 229930195729 fatty acid Natural products 0.000 title abstract 4
- 239000000194 fatty acid Substances 0.000 title abstract 4
- 150000004665 fatty acids Chemical class 0.000 title 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-L fumarate(2-) Chemical class [O-]C(=O)\C=C\C([O-])=O VZCYOOQTPOCHFL-OWOJBTEDSA-L 0.000 title 1
- -1 fatty acid fumarate derivatives Chemical class 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
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- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
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Abstract
La invención se refiere a derivados de fumarato de ácido graso, a composiciones que comprenden una cantidad efectiva de un derivado de fumarato de ácido graso y a métodos para tratar o prevenir cáncer, un trastorno metabólico o trastorno neurodegenerativo que comprende la administración de una cantidad efectiva de un derivado de fumarato de ácido graso.
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US29339610P | 2010-01-08 | 2010-01-08 | |
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ECSP12012097 ECSP12012097A (es) | 2010-01-08 | 2012-08-08 | Derivados de fumarato de ácido graso y sus usos |
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SG (1) | SG182414A1 (es) |
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- 2012-08-08 EC ECSP12012097 patent/ECSP12012097A/es unknown
- 2012-08-08 CO CO12133089A patent/CO6571913A2/es active IP Right Grant
- 2012-11-09 US US13/673,588 patent/US8969354B2/en not_active Expired - Fee Related
-
2015
- 2015-03-02 US US14/635,567 patent/US9289503B2/en not_active Expired - Fee Related
-
2016
- 2016-03-21 US US15/075,829 patent/US20160340294A1/en not_active Abandoned
- 2016-03-31 IL IL244858A patent/IL244858A/en not_active IP Right Cessation
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