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ECSP099344A - Modificaciones de cristal de la 3-(1h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona - Google Patents

Modificaciones de cristal de la 3-(1h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona

Info

Publication number
ECSP099344A
ECSP099344A EC2009009344A ECSP099344A ECSP099344A EC SP099344 A ECSP099344 A EC SP099344A EC 2009009344 A EC2009009344 A EC 2009009344A EC SP099344 A ECSP099344 A EC SP099344A EC SP099344 A ECSP099344 A EC SP099344A
Authority
EC
Ecuador
Prior art keywords
quinazolin
piperazin
indol
methyl
pirrol
Prior art date
Application number
EC2009009344A
Other languages
English (en)
Inventor
Dimitris Papoutsakis
Piotr Karpinski
Paul Allen Sutton
Stephanie Monnier
Elias Ndzie
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38921707&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP099344(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ECSP099344A publication Critical patent/ECSP099344A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La invención se refiere a una nueva forma cristalina de la sal de acetato de 3-(1.H.-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona, la cual se puede utilizar, por ejemplo, para trasplante.
EC2009009344A 2006-10-20 2009-05-19 Modificaciones de cristal de la 3-(1h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona ECSP099344A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85338406P 2006-10-20 2006-10-20

Publications (1)

Publication Number Publication Date
ECSP099344A true ECSP099344A (es) 2009-06-30

Family

ID=38921707

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2009009344A ECSP099344A (es) 2006-10-20 2009-05-19 Modificaciones de cristal de la 3-(1h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona

Country Status (23)

Country Link
US (1) US8865897B2 (es)
EP (1) EP2102195A1 (es)
JP (1) JP5302199B2 (es)
KR (1) KR20090073231A (es)
CN (2) CN101522664B (es)
AR (1) AR063491A1 (es)
AU (1) AU2007309558B2 (es)
BR (1) BRPI0717461A2 (es)
CA (1) CA2666965A1 (es)
CL (1) CL2007003006A1 (es)
EC (1) ECSP099344A (es)
IL (1) IL197962A (es)
MA (1) MA30886B1 (es)
MX (1) MX2009004048A (es)
MY (1) MY158026A (es)
NO (1) NO20091970L (es)
NZ (1) NZ576241A (es)
PE (1) PE20081133A1 (es)
RU (1) RU2481341C2 (es)
TN (1) TN2009000147A1 (es)
TW (1) TWI399374B (es)
WO (1) WO2008051440A1 (es)
ZA (1) ZA200902048B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008226645B2 (en) * 2007-03-09 2012-09-20 Novartis Ag Salts of 3- (1H-ind0l-3-yl) -4- [2- (4-methyl-piperazin-i-yl) -quinazolin-4-yl] -pyrrole-2, 5-di one
US9017528B2 (en) 2011-04-14 2015-04-28 Tel Nexx, Inc. Electro chemical deposition and replenishment apparatus
US9005409B2 (en) 2011-04-14 2015-04-14 Tel Nexx, Inc. Electro chemical deposition and replenishment apparatus
US9303329B2 (en) 2013-11-11 2016-04-05 Tel Nexx, Inc. Electrochemical deposition apparatus with remote catholyte fluid management

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE445613T1 (de) * 2000-11-07 2009-10-15 Novartis Pharma Gmbh Indolylmaleimidderivative als proteinkinase-c- inhibitoren
GB0504203D0 (en) * 2005-03-01 2005-04-06 Novartis Ag Organic compounds
EP2167487B1 (en) 2007-06-18 2015-02-18 Sanofi Pyrrole derivatives as p2y12 antagonists

Also Published As

Publication number Publication date
MA30886B1 (fr) 2009-11-02
TWI399374B (zh) 2013-06-21
IL197962A0 (en) 2009-12-24
MY158026A (en) 2016-08-30
JP2010506927A (ja) 2010-03-04
AU2007309558B2 (en) 2012-05-24
MX2009004048A (es) 2009-04-27
BRPI0717461A2 (pt) 2013-10-08
AU2007309558A1 (en) 2008-05-02
EP2102195A1 (en) 2009-09-23
WO2008051440A1 (en) 2008-05-02
RU2009118816A (ru) 2010-11-27
CN103265533A (zh) 2013-08-28
TN2009000147A1 (en) 2010-10-18
TW200829572A (en) 2008-07-16
CA2666965A1 (en) 2008-05-02
US8865897B2 (en) 2014-10-21
PE20081133A1 (es) 2008-09-16
US20100041884A1 (en) 2010-02-18
IL197962A (en) 2013-08-29
ZA200902048B (en) 2010-01-27
AR063491A1 (es) 2009-01-28
JP5302199B2 (ja) 2013-10-02
NZ576241A (en) 2012-05-25
NO20091970L (no) 2009-05-20
CN101522664A (zh) 2009-09-02
CL2007003006A1 (es) 2008-05-23
KR20090073231A (ko) 2009-07-02
RU2481341C2 (ru) 2013-05-10
CN101522664B (zh) 2013-06-12

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