ECSP066278A - Pirimidinas 2-sustituidas - Google Patents
Pirimidinas 2-sustituidasInfo
- Publication number
- ECSP066278A ECSP066278A EC2006006278A ECSP066278A ECSP066278A EC SP066278 A ECSP066278 A EC SP066278A EC 2006006278 A EC2006006278 A EC 2006006278A EC SP066278 A ECSP066278 A EC SP066278A EC SP066278 A ECSP066278 A EC SP066278A
- Authority
- EC
- Ecuador
- Prior art keywords
- substituted pyrimidines
- well
- description
- definitions indicated
- pesticides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
La invención se refiere a pirimidinas 2-sustituidas de la fórmula I Ien la que el índice n y los sutituyentes R1 hasta R3, así como L tienen las definiciones indicadas en la descripción y R4 corresponde a una de las fórmulas donde Ra, X y Rb tienen las definiciones indicadas en la descripción;así como procedimientos para su obtención, productos pesticidas que las contienen y el uso de las mismas como pesticidas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10333857 | 2003-07-24 | ||
| DE10357714 | 2003-12-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP066278A true ECSP066278A (es) | 2006-07-28 |
Family
ID=34117367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2006006278A ECSP066278A (es) | 2003-07-24 | 2006-01-11 | Pirimidinas 2-sustituidas |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7375108B2 (es) |
| EP (1) | EP1651618B1 (es) |
| JP (1) | JP2006528603A (es) |
| KR (1) | KR20060052857A (es) |
| AP (1) | AP2157A (es) |
| AR (1) | AR045100A1 (es) |
| AT (1) | ATE350370T1 (es) |
| AU (1) | AU2004261373B8 (es) |
| BR (1) | BRPI0412891A (es) |
| CA (1) | CA2532718A1 (es) |
| CO (1) | CO5660292A2 (es) |
| CR (1) | CR8184A (es) |
| CY (1) | CY1106391T1 (es) |
| DE (1) | DE502004002570D1 (es) |
| DK (1) | DK1651618T3 (es) |
| EA (1) | EA010566B1 (es) |
| EC (1) | ECSP066278A (es) |
| ES (1) | ES2279395T3 (es) |
| HR (1) | HRP20070057T3 (es) |
| IL (1) | IL172848A0 (es) |
| MA (1) | MA27949A1 (es) |
| MX (1) | MXPA06000038A (es) |
| NZ (1) | NZ545103A (es) |
| PE (1) | PE20050882A1 (es) |
| PL (1) | PL1651618T3 (es) |
| PT (1) | PT1651618E (es) |
| SI (1) | SI1651618T1 (es) |
| TW (1) | TW200516075A (es) |
| UY (1) | UY28436A1 (es) |
| WO (1) | WO2005012261A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1984902A (zh) * | 2004-07-14 | 2007-06-20 | 巴斯福股份公司 | 2－取代的嘧啶、其制备方法及其在防治致病性真菌中的用途 |
| CL2007002231A1 (es) * | 2006-08-02 | 2008-04-11 | Basf Ag | Uso de compuestos derivados de 5-(het) arilpirimidina para combatir hongos daninos; compuestos derivados de 5-(het) arilpirimidina; agente fungicida; y agente farmaceutico. |
| US8614223B2 (en) * | 2010-11-16 | 2013-12-24 | Acetylon Pharmaceuticals, Inc. | Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof |
| JP6626437B2 (ja) | 2013-10-08 | 2019-12-25 | アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | ヒストンデアセチラーゼ阻害剤とＨｅｒ２阻害剤またはＰＩ３Ｋ阻害剤のいずれかの組み合わせ |
| EP3055299B1 (en) | 2013-10-10 | 2021-01-06 | Acetylon Pharmaceuticals, Inc. | Pyrimidine hydroxy amide compounds as histone deacetylase inhibitors |
| EP3060217B1 (en) | 2013-10-24 | 2022-06-08 | Mayo Foundation for Medical Education and Research | Treatment of polycystic diseases with an hdac6 inhibitor |
| ES2806258T3 (es) | 2013-12-03 | 2021-02-17 | Acetylon Pharmaceuticals Inc | Combinaciones de inhibidores de histona desacetilasa y fármacos inmunomoduladores |
| US9464073B2 (en) | 2014-02-26 | 2016-10-11 | Acetylon Pharmaceuticals, Inc. | Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors |
| EA201790142A1 (ru) | 2014-07-07 | 2017-07-31 | Эситайлон Фармасьютикалз, Инк. | Лечение лейкоза ингибиторами гистондеацетилазы |
| JP2017537164A (ja) | 2014-12-05 | 2017-12-14 | ユニヴァーシティ・オブ・モデナ・アンド・レッジョ・エミリア | リンパ腫の治療に使用されるヒストン脱アセチル化酵素阻害剤とベンダムスチンとの組み合わせ |
| US10272084B2 (en) | 2015-06-01 | 2019-04-30 | Regenacy Pharmaceuticals, Llc | Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy |
| EP3445364A4 (en) | 2016-04-19 | 2019-11-27 | Acetylon Pharmaceuticals, Inc. | HDAC INHIBITORS, ONLY OR IN ASSOCIATION WITH BTK INHIBITORS, TO TREAT CHRONIC LYMPHOCYTIC LEUKEMIA |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001096314A1 (en) | 2000-06-13 | 2001-12-20 | Basf Aktiengesellschaft | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines |
| JP4361736B2 (ja) * | 2001-03-15 | 2009-11-11 | ビーエーエスエフ ソシエタス・ヨーロピア | ５−フェニルピリミジン、その製造方法、製造のための中間体および有害な菌類を防除するための使用 |
| PL371059A1 (en) | 2001-11-19 | 2005-06-13 | Basf Aktiengesellschaft | 5-phenylpyrimidines, agents comprising the same, method for production and use thereof |
-
2004
- 2004-07-15 NZ NZ545103A patent/NZ545103A/en unknown
- 2004-07-15 AT AT04741053T patent/ATE350370T1/de not_active IP Right Cessation
- 2004-07-15 AU AU2004261373A patent/AU2004261373B8/en not_active Ceased
- 2004-07-15 CA CA002532718A patent/CA2532718A1/en not_active Abandoned
- 2004-07-15 WO PCT/EP2004/007877 patent/WO2005012261A1/de active Application Filing
- 2004-07-15 US US10/564,013 patent/US7375108B2/en not_active Expired - Fee Related
- 2004-07-15 AP AP2006003497A patent/AP2157A/xx active
- 2004-07-15 ES ES04741053T patent/ES2279395T3/es not_active Expired - Lifetime
- 2004-07-15 EP EP04741053A patent/EP1651618B1/de not_active Expired - Lifetime
- 2004-07-15 SI SI200430228T patent/SI1651618T1/sl unknown
- 2004-07-15 DE DE502004002570T patent/DE502004002570D1/de not_active Expired - Lifetime
- 2004-07-15 MX MXPA06000038A patent/MXPA06000038A/es active IP Right Grant
- 2004-07-15 PT PT04741053T patent/PT1651618E/pt unknown
- 2004-07-15 DK DK04741053T patent/DK1651618T3/da active
- 2004-07-15 EA EA200600212A patent/EA010566B1/ru not_active IP Right Cessation
- 2004-07-15 JP JP2006520743A patent/JP2006528603A/ja active Pending
- 2004-07-15 PL PL04741053T patent/PL1651618T3/pl unknown
- 2004-07-15 KR KR1020067001493A patent/KR20060052857A/ko not_active Application Discontinuation
- 2004-07-15 BR BRPI0412891-5A patent/BRPI0412891A/pt not_active IP Right Cessation
- 2004-07-22 PE PE2004000707A patent/PE20050882A1/es not_active Application Discontinuation
- 2004-07-23 TW TW093122163A patent/TW200516075A/zh unknown
- 2004-07-23 UY UY28436A patent/UY28436A1/es unknown
- 2004-07-23 AR ARP040102631A patent/AR045100A1/es active IP Right Grant
-
2005
- 2005-12-27 IL IL172848A patent/IL172848A0/en not_active IP Right Cessation
-
2006
- 2006-01-11 EC EC2006006278A patent/ECSP066278A/es unknown
- 2006-01-11 CR CR8184A patent/CR8184A/es unknown
- 2006-01-24 CO CO06006393A patent/CO5660292A2/es not_active Application Discontinuation
- 2006-02-15 MA MA28806A patent/MA27949A1/fr unknown
-
2007
- 2007-02-14 HR HR20070057T patent/HRP20070057T3/xx unknown
- 2007-03-16 CY CY20071100372T patent/CY1106391T1/el unknown
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