Nothing Special   »   [go: up one dir, main page]

EA202092445A1 - Способ получения 2-метил-4-(2,6,6-триметил-1-циклогексен-1-ил)-2-бутеналя - Google Patents

Способ получения 2-метил-4-(2,6,6-триметил-1-циклогексен-1-ил)-2-бутеналя

Info

Publication number
EA202092445A1
EA202092445A1 EA202092445A EA202092445A EA202092445A1 EA 202092445 A1 EA202092445 A1 EA 202092445A1 EA 202092445 A EA202092445 A EA 202092445A EA 202092445 A EA202092445 A EA 202092445A EA 202092445 A1 EA202092445 A1 EA 202092445A1
Authority
EA
Eurasian Patent Office
Prior art keywords
butenal
cyclohexen
trimethyl
methyl
producing
Prior art date
Application number
EA202092445A
Other languages
English (en)
Inventor
Ян Шютц
Original Assignee
ДСМ АйПи АССЕТС Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ДСМ АйПи АССЕТС Б.В. filed Critical ДСМ АйПи АССЕТС Б.В.
Publication of EA202092445A1 publication Critical patent/EA202092445A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/225—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing rings other than six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Настоящее изобретение касается улучшенного способа получения 2-метил-4-(2,6,6-триметил-1-циклогексен-1-ил)-2-бутеналя формулы (I) и его производных согласно нижеследующей реакционной схеме, где значения всех переменных указаны в формуле изобретения. Благодаря улучшениям была значительно увеличена селективность данного процесса и уменьшено формирование побочных продуктов.
EA202092445A 2018-04-11 2019-04-08 Способ получения 2-метил-4-(2,6,6-триметил-1-циклогексен-1-ил)-2-бутеналя EA202092445A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18166706 2018-04-11
PCT/EP2019/058787 WO2019197326A1 (en) 2018-04-11 2019-04-08 Process for the production of 2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-butenal

Publications (1)

Publication Number Publication Date
EA202092445A1 true EA202092445A1 (ru) 2021-02-17

Family

ID=62002531

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202092445A EA202092445A1 (ru) 2018-04-11 2019-04-08 Способ получения 2-метил-4-(2,6,6-триметил-1-циклогексен-1-ил)-2-бутеналя

Country Status (6)

Country Link
US (1) US11370738B2 (ru)
EP (1) EP3774710A1 (ru)
JP (1) JP7298088B2 (ru)
CN (1) CN111954655A (ru)
EA (1) EA202092445A1 (ru)
WO (1) WO2019197326A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114409580B (zh) * 2021-12-27 2024-06-07 厦门金达威维生素有限公司 一种维生素a中间体十四醛的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2369156A (en) * 1940-08-22 1945-02-13 Research Corp Process of making vitamin a
US2451740A (en) * 1946-12-24 1948-10-19 Hoffmann La Roche Process for the manufacture of an aldehyde
CH255097A (de) * 1946-12-24 1948-06-15 Hoffmann La Roche Verfahren zur Darstellung eines Aldehyds aus B-Jonon.
GB1156818A (en) * 1966-09-27 1969-07-02 Vni Vitaminny I Method of Producing 4-[2<1>,6<1>,6<1>, Trimethylcyclohexene-1<1>-yl]-2-Methylbutene-2-al-1.
CN1125804C (zh) 2000-10-18 2003-10-29 浙江新和成股份有限公司 维生素a中间体的制备工艺
EP1764359A1 (en) * 2005-09-16 2007-03-21 DSM IP Assets B.V. Process for the preparation of glycidic ester and an aldehyde

Also Published As

Publication number Publication date
US20210130277A1 (en) 2021-05-06
BR112020020570A2 (pt) 2021-01-12
JP2021518350A (ja) 2021-08-02
EP3774710A1 (en) 2021-02-17
US11370738B2 (en) 2022-06-28
WO2019197326A1 (en) 2019-10-17
CN111954655A (zh) 2020-11-17
JP7298088B2 (ja) 2023-06-27

Similar Documents

Publication Publication Date Title
MX2022005726A (es) Sintesis mejorada del compuesto inhibidor de g12c de kras.
EA201890751A1 (ru) Противогрибковые соединения и способы их получения
EA202091466A1 (ru) Синтез сокристалла 1:1:1 1-циано-2-(4-циклопропилбензил)-4-(-d-глюкопираноз-1-ил)бензола, l-пролина и воды
MX2020006306A (es) Método novedoso para producir 4,5-dihidroisoxazol 5,5-disustituido.
SG10201902609TA (en) Method for producing novel nitrogen-containing compound or salt thereof, and production intermediate of same
SG11201906688VA (en) Novel ester compounds, method for the production thereof and use thereof
ZA202204803B (en) An efficient new process for synthesis of 2-amino-5-chloro-n-,3-dimethylbenzamide
MX2018011877A (es) Proceso mejorado para la preparacion de tartrato de butorfanol.
WO2021205388A3 (en) An improved process for the preparation of semaglutide side chain
EA202090933A1 (ru) Способ получения гербицидных соединений пиридазинона
EA202092445A1 (ru) Способ получения 2-метил-4-(2,6,6-триметил-1-циклогексен-1-ил)-2-бутеналя
EA202192581A1 (ru) Композиции d-метирозина и способы их получения
ATE423764T1 (de) Verfahren zur herstellung von hydrazon-derivaten
MX2019004182A (es) Proceso para la fabricacion de 2,6-dimetil-5-hepten-1-al.
MY189631A (en) Methods of chemical synthesis of substituted 10h-phenothiazine-3,7-diamine compounds
EA202091588A1 (ru) Способ получения аминопиримидина и его промежуточных продуктов
MX2021007511A (es) Procedimiento para la preparacion de anilinas sustituidas.
EA202192840A1 (ru) Способ получения соединений карбамоилоксиметилтриазолциклогексиловой кислоты
MX2022001167A (es) Metodo para el tratamiento de una composicion que comprende vainillina natural.
EA202190330A1 (ru) Способ получения полиморфной формы робенакоксиба
EA201792655A1 (ru) Способ синтеза 9,9-бис(гидроксиметил)флуорена
EP4289844A3 (en) A process for making palbociclib
MX2020012880A (es) Produccion de hmf catalizada por mezcla de sal y acido.
MX2021001530A (es) Metodo de produccion de esteres carbonicos.
MX2019006343A (es) Sintesis de acido tiosulfonico por un paso de acoplamiento oxidativo mediado por peryodato de un acido tiosulfonico con una anilina.