EA201991065A1 - Вакцина против свиного парвовируса - Google Patents
Вакцина против свиного парвовирусаInfo
- Publication number
- EA201991065A1 EA201991065A1 EA201991065A EA201991065A EA201991065A1 EA 201991065 A1 EA201991065 A1 EA 201991065A1 EA 201991065 A EA201991065 A EA 201991065A EA 201991065 A EA201991065 A EA 201991065A EA 201991065 A1 EA201991065 A1 EA 201991065A1
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- Eurasian Patent Office
- Prior art keywords
- present
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- amino acid
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Links
- 241000125945 Protoparvovirus Species 0.000 title 1
- 235000015277 pork Nutrition 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 101000714457 Chaetoceros protobacilladnavirus 2 Capsid protein Proteins 0.000 abstract 4
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 4
- 235000001014 amino acid Nutrition 0.000 abstract 4
- 230000002163 immunogen Effects 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 241000702619 Porcine parvovirus Species 0.000 abstract 2
- WHUUTDBJXJRKMK-VKHMYHEASA-L glutamate group Chemical group N[C@@H](CCC(=O)[O-])C(=O)[O-] WHUUTDBJXJRKMK-VKHMYHEASA-L 0.000 abstract 1
- 125000000291 glutamic acid group Chemical group N[C@@H](CCC(O)=O)C(=O)* 0.000 abstract 1
- 125000000404 glutamine group Chemical group N[C@@H](CCC(N)=O)C(=O)* 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 125000003607 serino group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 abstract 1
- 125000000341 threoninyl group Chemical group [H]OC([H])(C([H])([H])[H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/23—Parvoviridae, e.g. feline panleukopenia virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14323—Virus like particles [VLP]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14371—Demonstrated in vivo effect
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
Настоящее изобретение касается, в числе прочего, вирусного белка 2 (VP2) свиного парвовируса (PPV), имеющего в аминокислотной позиции 228 глутаминово-кислотный остаток или глутаматный остаток, и/или в аминокислотной позиции 414 сериновый остаток, и/или в аминокислотной позиции 419 глутаминовый остаток, и/или в аминокислотной позиции 436 треониновый остаток. Кроме того, настоящее изобретение касается иммуногенных композиций, включающих вирусный белок 2 (VP2) свиного парвовируса (PPV). Кроме того, настоящее изобретение касается способов иммунизации субъекта, включающих введение такому субъекту иммуногенной композиции согласно настоящему изобретению. Кроме того, настоящее изобретение касается способов лечения или предотвращения клинических признаков вызываемых инфекцией PPV у субъекта, который в этом нуждается, причем способ включает введение субъекту терапевтически эффективного количества иммуногенной композиции согласно настоящему изобретению.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16197091 | 2016-11-03 | ||
PCT/EP2017/078015 WO2018083154A1 (en) | 2016-11-03 | 2017-11-02 | Vaccine against porcine parvovirus |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201991065A1 true EA201991065A1 (ru) | 2019-11-29 |
Family
ID=57223617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201991065A EA201991065A1 (ru) | 2016-11-03 | 2017-11-02 | Вакцина против свиного парвовируса |
Country Status (16)
Country | Link |
---|---|
US (2) | US10485866B2 (ru) |
EP (1) | EP3534945A1 (ru) |
JP (2) | JP6876127B2 (ru) |
KR (2) | KR20240090735A (ru) |
CN (1) | CN109803678B (ru) |
AU (1) | AU2017353378B2 (ru) |
BR (1) | BR112019009133A2 (ru) |
CA (1) | CA3042573A1 (ru) |
CL (1) | CL2019001049A1 (ru) |
EA (1) | EA201991065A1 (ru) |
MX (1) | MX2019005137A (ru) |
MY (1) | MY191490A (ru) |
PH (1) | PH12019500954A1 (ru) |
TW (1) | TWI781962B (ru) |
UA (1) | UA127859C2 (ru) |
WO (1) | WO2018083154A1 (ru) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140170180A1 (en) | 2012-12-17 | 2014-06-19 | Boehringer Ingelheim Vetmedica, Inc. | Porcine parvovirus 5a, methods of use and vaccine |
KR102664662B1 (ko) | 2016-11-03 | 2024-05-14 | 베링거잉겔하임베트메디카게엠베하 | 돼지 파보바이러스 및 돼지 생식기 및 호흡기 증후군 바이러스에 대한 백신 및 이의 제조 방법 |
EA201991065A1 (ru) | 2016-11-03 | 2019-11-29 | Вакцина против свиного парвовируса | |
US11013796B2 (en) | 2018-08-30 | 2021-05-25 | Iowa State University Research Foundation, Inc. | Porcine parainfluenza virus type 1 isolates and immunogenic compositions therefrom |
KR102117811B1 (ko) * | 2018-12-05 | 2020-06-02 | 대한민국(농림축산식품부 농림축산검역본부장) | 재조합 돼지파보바이러스 항원 단백질 및 이의 용도 |
WO2020206452A1 (en) | 2019-04-04 | 2020-10-08 | Boehringer Ingelheim Animal Health USA Inc. | Porcine circovirus type 3 (pcv3) vaccines, and production and uses thereof |
CN110845580A (zh) * | 2019-11-05 | 2020-02-28 | 中国农业科学院兰州兽医研究所 | 一种猪细小病毒样颗粒的组装及其免疫原性鉴定方法 |
KR102550709B1 (ko) | 2021-05-03 | 2023-07-06 | 대한민국 | 돼지 생식기 호흡기 증후군 바이러스 PRRS2/Kor/CBJE19/2010 바이러스주 |
KR102550701B1 (ko) | 2021-05-03 | 2023-07-05 | 대한민국 | 돼지 생식기 호흡기 증후군 바이러스 PRRS2/Kor/GGYC45/2010 바이러스주 |
KR102550715B1 (ko) | 2021-05-03 | 2023-07-05 | 대한민국 | 돼지 생식기 호흡기 증후군 바이러스 PRRS2/Kor/GBGJ22/2011 바이러스주 |
CN114480439A (zh) * | 2022-02-23 | 2022-05-13 | 成都史纪生物制药有限公司 | 一种猪细小病毒vp2蛋白基因及其应用 |
CN117866053B (zh) * | 2024-01-10 | 2024-07-02 | 武汉珈创生物技术股份有限公司 | 同时检测多种猪细小病毒的多克隆抗体及其制备和应用 |
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CN106039304B (zh) * | 2016-05-28 | 2021-02-05 | 青岛易邦生物工程有限公司 | 一种猪细小病毒、猪流行性腹泻、大肠埃希氏菌三联疫苗 |
EA201991065A1 (ru) * | 2016-11-03 | 2019-11-29 | Вакцина против свиного парвовируса | |
KR102664662B1 (ko) | 2016-11-03 | 2024-05-14 | 베링거잉겔하임베트메디카게엠베하 | 돼지 파보바이러스 및 돼지 생식기 및 호흡기 증후군 바이러스에 대한 백신 및 이의 제조 방법 |
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2017
- 2017-11-02 EA EA201991065A patent/EA201991065A1/ru unknown
- 2017-11-02 JP JP2019521716A patent/JP6876127B2/ja active Active
- 2017-11-02 US US15/801,730 patent/US10485866B2/en active Active
- 2017-11-02 WO PCT/EP2017/078015 patent/WO2018083154A1/en unknown
- 2017-11-02 MY MYPI2019002115A patent/MY191490A/en unknown
- 2017-11-02 AU AU2017353378A patent/AU2017353378B2/en active Active
- 2017-11-02 CN CN201780062570.5A patent/CN109803678B/zh active Active
- 2017-11-02 UA UAA201905861A patent/UA127859C2/uk unknown
- 2017-11-02 MX MX2019005137A patent/MX2019005137A/es unknown
- 2017-11-02 BR BR112019009133A patent/BR112019009133A2/pt unknown
- 2017-11-02 CA CA3042573A patent/CA3042573A1/en active Pending
- 2017-11-02 KR KR1020247016936A patent/KR20240090735A/ko active Search and Examination
- 2017-11-02 TW TW106137853A patent/TWI781962B/zh active
- 2017-11-02 EP EP17801619.2A patent/EP3534945A1/en active Pending
- 2017-11-02 KR KR1020197015848A patent/KR102669319B1/ko active IP Right Grant
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2019
- 2019-04-17 CL CL2019001049A patent/CL2019001049A1/es unknown
- 2019-04-29 PH PH12019500954A patent/PH12019500954A1/en unknown
- 2019-10-10 US US16/598,110 patent/US10799578B2/en active Active
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2021
- 2021-02-19 JP JP2021025031A patent/JP2021097679A/ja active Pending
Also Published As
Publication number | Publication date |
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KR20240090735A (ko) | 2024-06-21 |
WO2018083154A1 (en) | 2018-05-11 |
BR112019009133A2 (pt) | 2019-07-16 |
JP6876127B2 (ja) | 2021-05-26 |
CA3042573A1 (en) | 2018-05-11 |
KR102669319B1 (ko) | 2024-05-28 |
AU2017353378B2 (en) | 2024-03-14 |
TWI781962B (zh) | 2022-11-01 |
MX2019005137A (es) | 2019-06-20 |
CL2019001049A1 (es) | 2019-08-16 |
CN109803678A (zh) | 2019-05-24 |
CN109803678B (zh) | 2023-08-22 |
UA127859C2 (uk) | 2024-01-31 |
US10799578B2 (en) | 2020-10-13 |
US20180133309A1 (en) | 2018-05-17 |
US20200030438A1 (en) | 2020-01-30 |
MY191490A (en) | 2022-06-28 |
JP2021097679A (ja) | 2021-07-01 |
JP2020500012A (ja) | 2020-01-09 |
PH12019500954A1 (en) | 2019-12-02 |
AU2017353378A1 (en) | 2019-05-02 |
KR20190089899A (ko) | 2019-07-31 |
EP3534945A1 (en) | 2019-09-11 |
US10485866B2 (en) | 2019-11-26 |
TW201829446A (zh) | 2018-08-16 |
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