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EA201000797A1 - Аминотриазолы в качестве ингибиторов pi3k - Google Patents

Аминотриазолы в качестве ингибиторов pi3k

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Publication number
EA201000797A1
EA201000797A1 EA201000797A EA201000797A EA201000797A1 EA 201000797 A1 EA201000797 A1 EA 201000797A1 EA 201000797 A EA201000797 A EA 201000797A EA 201000797 A EA201000797 A EA 201000797A EA 201000797 A1 EA201000797 A1 EA 201000797A1
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EA
Eurasian Patent Office
Prior art keywords
compounds
aminotriazoles
pi3k inhibitors
pharmaceuticals
preparation
Prior art date
Application number
EA201000797A
Other languages
English (en)
Inventor
Найджель Рэмздэн
Кэсрин Бел
Эндру Кэнсфилд
Джесс Тэйлер
Михиро Зуносе
Дэвид Мидлмисс
Гиттэ Нойбауэр
Original Assignee
Целльзом Лимитид
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Publication date
Application filed by Целльзом Лимитид filed Critical Целльзом Лимитид
Publication of EA201000797A1 publication Critical patent/EA201000797A1/ru

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Изобретение касается соединений формулы (I). Указанные соединения используют в качестве ингибиторов протеинкиназы, в частности ингибиторов PI3K, для лечения или профилактики иммунологических, воспалительных, аутоиммунных или аллергических нарушений. Изобретение также касается фармацевтических композиций, включающих указанные соединения, получения указанных соединений, а также получения лекарственных средств и применения в качестве лекарственных средств.
EA201000797A 2007-11-27 2008-11-21 Аминотриазолы в качестве ингибиторов pi3k EA201000797A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07121607 2007-11-27
US7800608P 2008-07-03 2008-07-03
US8696308P 2008-08-07 2008-08-07
PCT/EP2008/066001 WO2009068482A1 (en) 2007-11-27 2008-11-21 Amino triazoles as pi3k inhibitors

Publications (1)

Publication Number Publication Date
EA201000797A1 true EA201000797A1 (ru) 2011-02-28

Family

ID=39226746

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201000797A EA201000797A1 (ru) 2007-11-27 2008-11-21 Аминотриазолы в качестве ингибиторов pi3k

Country Status (16)

Country Link
US (1) US8865699B2 (ru)
EP (1) EP2222674B8 (ru)
JP (1) JP2011504900A (ru)
KR (1) KR20100086492A (ru)
CN (1) CN101952285A (ru)
AU (1) AU2008328882A1 (ru)
BR (1) BRPI0819606A2 (ru)
CA (1) CA2706578A1 (ru)
EA (1) EA201000797A1 (ru)
ES (1) ES2558840T3 (ru)
IL (1) IL205682A0 (ru)
MX (1) MX2010005700A (ru)
SG (1) SG186040A1 (ru)
TW (1) TW200936583A (ru)
UA (1) UA102828C2 (ru)
WO (1) WO2009068482A1 (ru)

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Also Published As

Publication number Publication date
US20110021497A1 (en) 2011-01-27
CN101952285A (zh) 2011-01-19
JP2011504900A (ja) 2011-02-17
TW200936583A (en) 2009-09-01
EP2222674A1 (en) 2010-09-01
WO2009068482A1 (en) 2009-06-04
AU2008328882A1 (en) 2009-06-04
SG186040A1 (en) 2012-12-28
WO2009068482A8 (en) 2010-07-29
EP2222674B8 (en) 2016-01-06
EP2222674B1 (en) 2015-11-11
US8865699B2 (en) 2014-10-21
KR20100086492A (ko) 2010-07-30
ES2558840T3 (es) 2016-02-09
UA102828C2 (en) 2013-08-27
BRPI0819606A2 (pt) 2017-05-09
MX2010005700A (es) 2010-06-11
CA2706578A1 (en) 2009-06-04
IL205682A0 (en) 2010-11-30

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