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EA200901529A1 - Производные арилоазол-2-илцианоэтиламина, способ их получения и способ их применения - Google Patents

Производные арилоазол-2-илцианоэтиламина, способ их получения и способ их применения

Info

Publication number
EA200901529A1
EA200901529A1 EA200901529A EA200901529A EA200901529A1 EA 200901529 A1 EA200901529 A1 EA 200901529A1 EA 200901529 A EA200901529 A EA 200901529A EA 200901529 A EA200901529 A EA 200901529A EA 200901529 A1 EA200901529 A1 EA 200901529A1
Authority
EA
Eurasian Patent Office
Prior art keywords
derivatives
ilcyanoethylamine
aryloazole
production
ylcyanoethylamine
Prior art date
Application number
EA200901529A
Other languages
English (en)
Other versions
EA016912B1 (ru
Inventor
Марк Дейвид Солл
Лоик Патрик Лё Ир Де Фальуа
Скот Кевин Хубер
Хуонг Ик Ли
Дуглас Эдвард Уилкинсон
Роберт Томас Джекобс
Original Assignee
Мериал Лимитед
Авентис Эгрикалчер
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мериал Лимитед, Авентис Эгрикалчер filed Critical Мериал Лимитед
Publication of EA200901529A1 publication Critical patent/EA200901529A1/ru
Publication of EA016912B1 publication Critical patent/EA016912B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/34—Nitriles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A61P33/12—Schistosomicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)

Abstract

Настоящее изобретение относится к новым производным арилоазол-2-илцианоэтиламина формулы (I)в которой R, R, R, R, R, Р, Q, V, W, X, Y, Z и а представляют собой группы, определённые в описании, их композициям, способам их получения и их применению в качестве пестицидов.
EA200901529A 2007-05-15 2008-05-12 Производные арилоазол-2-илцианоэтиламина, способ их получения и способ их применения EA016912B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93048507P 2007-05-15 2007-05-15
PCT/US2008/063417 WO2008144275A1 (en) 2007-05-15 2008-05-12 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof

Publications (2)

Publication Number Publication Date
EA200901529A1 true EA200901529A1 (ru) 2010-04-30
EA016912B1 EA016912B1 (ru) 2012-08-30

Family

ID=38608776

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200901529A EA016912B1 (ru) 2007-05-15 2008-05-12 Производные арилоазол-2-илцианоэтиламина, способ их получения и способ их применения

Country Status (31)

Country Link
US (2) US8088801B2 (ru)
EP (4) EP2155699B9 (ru)
JP (1) JP5562840B2 (ru)
KR (3) KR101292600B1 (ru)
CN (2) CN101743230B (ru)
AR (1) AR066571A1 (ru)
AU (1) AU2008254279B2 (ru)
BR (2) BR122018010599B1 (ru)
CA (1) CA2684764C (ru)
CL (1) CL2008001430A1 (ru)
CY (3) CY1116858T1 (ru)
DK (4) DK2155699T5 (ru)
EA (1) EA016912B1 (ru)
ES (4) ES2825198T3 (ru)
HK (3) HK1141026A1 (ru)
HR (4) HRP20151058T2 (ru)
HU (4) HUE029127T2 (ru)
LT (3) LT2639228T (ru)
ME (1) ME03373B (ru)
MX (1) MX2009012082A (ru)
MY (1) MY154464A (ru)
NZ (1) NZ580968A (ru)
PL (4) PL3428148T3 (ru)
PT (4) PT3428148T (ru)
RS (4) RS55271B1 (ru)
SG (3) SG169989A1 (ru)
SI (4) SI2155699T1 (ru)
TR (1) TR201903663T4 (ru)
TW (1) TWI441633B (ru)
UY (1) UY31093A1 (ru)
WO (1) WO2008144275A1 (ru)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010005685A (es) * 2007-11-26 2010-09-28 Merial Ltd Sistemas de solventes para formulaciones de vaciado determinado para combatir parasitos.
WO2010048191A1 (en) 2008-10-21 2010-04-29 Merial Limited Thioamide compounds, method of making and method of using thereof
AU2009313920B2 (en) 2008-11-14 2014-10-23 Boehringer Ingelheim Animal Health USA Inc. Enantiomerically enriched aryloazol- 2 -yl cyanoethylamino paraciticidal compounds
AP3359A (en) 2008-11-19 2015-07-31 Merial Ltd Compositions comprising 1-arylpyrazole alone or incombination with formamidine for the treatment of parasitic infection
ES2537424T3 (es) 2008-12-04 2015-06-08 Merial Limited Derivados de dímeros de avermectina y de milbemicina
DE102009012423A1 (de) * 2009-03-10 2010-09-16 Bayer Animal Health Gmbh Zubereitung auf Ölbasis
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
WO2013039948A1 (en) 2011-09-12 2013-03-21 Merial Limited Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
WO2013057624A1 (en) 2011-10-19 2013-04-25 Ah Usa 42 Llc Use of aminoacetonitrile derivatives against endoparasites
BR112014011775A8 (pt) 2011-11-17 2017-07-11 Merial Ltd Composições compreendendo um aril pirazol e um imidazol substituído, métodos e usos dos mesmos
CA3082432C (en) 2011-12-02 2023-01-03 Boehringer Ingelheim Animal Health USA Inc. Long-acting injectable moxidectin formulations and novel moxidectin crystal forms
PT109395B (pt) 2012-02-06 2020-10-01 Boehringer Ingelheim Animal Health USA Inc. Composições veterinárias orais parasiticidas compreendendo agentes activos de actuação sistémica, métodos e as suas utilizações
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
BR112014024832B1 (pt) 2012-04-04 2022-05-31 Intervet International B.V. Método para a preparação de uma composição farmacêutica veterinária mastigável macia, composição farmacêutica, e, uso da composição
KR102114598B1 (ko) 2012-04-20 2020-05-25 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 벤즈이미다졸 유도체를 포함하는 구충 조성물, 방법 및 그의 용도
IN2015MN00404A (ru) 2012-08-30 2015-09-04 Univ Tokyo
US8822689B2 (en) * 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
JP6506694B2 (ja) 2012-11-20 2019-04-24 メリアル インコーポレイテッド 駆虫性化合物及び組成物並びにこれらの使用方法
JP6335268B2 (ja) * 2013-03-14 2018-05-30 ダウ アグロサイエンシィズ エルエルシー ある種の農薬的利用性を有する分子、ならびにそれらに関する中間体、組成物および方法
CN103267808A (zh) * 2013-04-22 2013-08-28 上海谱尼测试技术有限公司 一种电子电气产品中地乐酚含量的测定方法
PL3063144T3 (pl) 2013-11-01 2022-01-31 Boehringer Ingelheim Animal Health USA Inc. Przeciwpasożytnicze i szkodniczobójcze związki izoksazolinowe
BR112016023898A8 (pt) 2014-04-17 2021-03-30 Basf Se uso de compostos malononitrila para proteger animais de parasitas
CA2949511A1 (en) 2014-05-19 2015-11-26 Merial, Inc. Anthelmintic compounds
WO2015196014A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
AU2015339096B2 (en) 2014-10-31 2018-08-02 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal composition comprising fipronil
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
PL3298027T3 (pl) 2015-05-20 2021-11-08 Boehringer Ingelheim Animal Health USA Inc. Przeciwrobacze związki depsipeptydów
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
CN106106475A (zh) * 2016-06-22 2016-11-16 叶松 一种防治梨食芽蛾的组合物及其制备方法
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
WO2018071535A1 (en) 2016-10-14 2018-04-19 Merial, Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
MX2019005628A (es) 2016-11-16 2019-12-18 Boehringer Ingelheim Animal Health Usa Inc Compuestos depsipeptidos antihelminticos.
CN106918705B (zh) * 2017-01-22 2023-06-13 贵州勤邦食品安全科学技术有限公司 检测甲氰菊酯的试纸及其应用
HUE061497T2 (hu) 2017-08-14 2023-07-28 Boehringer Ingelheim Animal Health Usa Inc Peszticid és paraziticid hatású pirazol-izoxazolin vegyületek
CN108033925A (zh) * 2017-12-27 2018-05-15 温州大学 一种苯并三氮唑化合物及其制备方法
EP3749096A1 (en) 2018-02-08 2020-12-16 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
WO2020014068A1 (en) 2018-07-09 2020-01-16 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic heterocyclic compounds
CN108752217B (zh) * 2018-07-18 2021-08-06 浙江沙星科技有限公司 一种度鲁特韦关键中间体2,4-二氟苄胺的合成方法
US11773066B2 (en) 2018-11-20 2023-10-03 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
CN109694472B (zh) * 2018-12-13 2021-06-29 万华化学集团股份有限公司 功能性聚醚起始剂及其合成和在聚醚合成中的应用
CA3129329A1 (en) 2019-03-01 2020-09-10 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
CN113825543B (zh) 2019-03-19 2024-09-06 勃林格殷格翰动物保健有限公司 驱虫的氮杂-苯并噻吩和氮杂-苯并呋喃化合物
CN110470768B (zh) * 2019-08-27 2022-05-24 谱尼测试集团吉林有限公司 一种测定水质中吡嘧磺隆、三唑磷、丁草胺残留量的方法
JP2023528822A (ja) 2020-05-29 2023-07-06 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 駆虫性複素環式化合物
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
CN118715163A (zh) 2022-02-17 2024-09-27 勃林格殷格翰动物保健有限公司 用于提供流体制品邮寄封的方法和系统

Family Cites Families (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL160809C (nl) 1970-05-15 1979-12-17 Duphar Int Res Werkwijze ter bereiding van benzoylureumverbindingen, alsmede werkwijze ter bereiding van insekticide prepara- ten op basis van benzoylureumverbindingen.
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
JPS4914624A (ru) 1972-06-08 1974-02-08
US3818047A (en) 1972-08-07 1974-06-18 C Henrick Substituted pyrones
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
CH604517A5 (ru) 1976-08-19 1978-09-15 Ciba Geigy Ag
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4134973A (en) 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4144352A (en) 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
US4203976A (en) 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
JPS57139012A (en) 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4427663A (en) 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
DE3235931A1 (de) 1982-09-29 1984-03-29 Bayer Ag, 5090 Leverkusen Koeder zur bekaempfung von ungeziefer
JPS59199673A (ja) 1983-04-25 1984-11-12 Sumitomo Chem Co Ltd 含窒素複素環化合物、その製造法およびそれを有効成分とする有害生物防除剤
DE3580444D1 (en) 1984-10-18 1990-12-13 Ciba Geigy Ag Benzoylphenylharnstoffe.
ATE67493T1 (de) 1985-02-04 1991-10-15 Bayer Agrochem Kk Heterocyclische verbindungen.
EP0237482A1 (de) 1986-03-06 1987-09-16 Ciba-Geigy Ag C(29)-Carbonyloxi-milbemycin-Derivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen
ATE89560T1 (de) 1986-03-25 1993-06-15 Sankyo Co Makrolid-derivate, ihre herstellung und ihre verwendung.
ATE75745T1 (de) 1986-07-02 1992-05-15 Ciba Geigy Ag Pestizide.
US4855317A (en) 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
US4871719A (en) 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
US4874749A (en) 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
DE3888936T2 (de) 1987-11-03 1994-07-21 Beecham Group Plc Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.
NZ232422A (en) 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
NZ247278A (en) 1991-02-12 1995-03-28 Ancare Distributors Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier
US5345377A (en) 1992-10-30 1994-09-06 Electric Power Research Institute, Inc. Harmonic controller for an active power line conditioner
GB9300883D0 (en) 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
US5537529A (en) * 1993-04-22 1996-07-16 Apple Computer, Inc. Apparatus and method for creating versions of computer models and creating communications incorporating created versions therefrom
US5399582A (en) 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
US5806078A (en) * 1994-06-09 1998-09-08 Softool Corporation Version management system
AUPM969994A0 (en) 1994-11-28 1994-12-22 Virbac S.A. Equine anthelmintic formulations
US5962499A (en) 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
FR2739255B1 (fr) 1995-09-29 1998-09-04 Rhone Merieux Composition antiparasitaire pour le traitement et la protection des animaux de compagnie
US6366933B1 (en) * 1995-10-27 2002-04-02 At&T Corp. Method and apparatus for tracking and viewing changes on the web
FR2752525B1 (fr) 1996-08-20 2000-05-05 Rhone Merieux Procede de lutte contre les myiases des cheptels bovins et ovins et compositions pour la mise en oeuvre de ce procede
IE80657B1 (en) 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
US6010710A (en) 1996-03-29 2000-01-04 Merial Direct pour-on skin solution for antiparasitic use in cattle and sheep
US5885607A (en) 1996-03-29 1999-03-23 Rhone Merieux N-phenylpyrazole-based anti-flea and anti-tick external device for cats and dogs
US6366930B1 (en) * 1996-04-12 2002-04-02 Computer Associates Think, Inc. Intelligent data inventory & asset management systems method and apparatus
FR2753377B1 (fr) 1996-09-19 1999-09-24 Rhone Merieux Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides
US6426333B1 (en) 1996-09-19 2002-07-30 Merial Spot-on formulations for combating parasites
US6998131B2 (en) 1996-09-19 2006-02-14 Merial Limited Spot-on formulations for combating parasites
US6207647B1 (en) 1997-07-18 2001-03-27 Smithkline Beecham Corporation RatA
US5909689A (en) * 1997-09-18 1999-06-01 Sony Corporation Automatic update of file versions for files shared by several computers which record in respective file directories temporal information for indicating when the files have been created
US7062497B2 (en) * 1998-01-22 2006-06-13 Adobe Systems Incorporated Maintaining document state history
US6239077B1 (en) * 1998-05-01 2001-05-29 Nihon Nohyaku Co., Ltd. Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof
DE19823396A1 (de) 1998-05-26 1999-12-02 Bayer Ag Synergistische insektizide Mischungen
US6174540B1 (en) 1998-09-14 2001-01-16 Merck & Co., Inc. Long acting injectable formulations containing hydrogenated caster oil
EP1094411A1 (en) * 1999-10-20 2001-04-25 Sun Microsystems, Inc. Handling of different versions of a document
US6787342B2 (en) 2000-02-16 2004-09-07 Merial Limited Paste formulations
US6399786B1 (en) 2000-07-14 2002-06-04 Merck & Co., Inc. Nonacyclic nodulisporic acid derivatives
WO2002050052A1 (en) 2000-12-20 2002-06-27 Syngenta Participations Ag N-acyl aminoacetonitriles having pesticidal properties
AU2002234588B2 (en) 2000-12-20 2005-03-24 Elanco Tiergesundheit Ag Organic compounds
AR035531A1 (es) 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
CN1241907C (zh) 2001-05-15 2006-02-15 诺瓦提斯公司 有机化合物
TWI236341B (en) 2001-06-15 2005-07-21 Novartis Ag Aminoacetonitrile compounds for use in the control of endoparasites
RU2296119C2 (ru) 2001-10-04 2007-03-27 Новартис Аг Цианоацетильные соединения, способ их получения и их применение (варианты), композиция и способ борьбы с паразитами
US7262209B2 (en) 2001-10-04 2007-08-28 Novartis Animal Health Us, Inc. Carbonyloxy-cyanomethyl compounds as antiparasitic agents
TW200300140A (en) 2001-11-14 2003-05-16 Novartis Ag Organic compounds
AR037746A1 (es) 2001-12-06 2004-12-01 Novartis Ag Compuestos derivados de amidoacetonitrilo, un procedimiento para su preparacion, un procedimiento para la preparacion de compuestos intermediarios, una composicion para combatir parasitos, un procedimiento para combatir dichos parasitos, y el empleo de dichos derivados para la preparacion de una com
AR038156A1 (es) 2002-01-21 2004-12-29 Novartis Ag Compuestos de amidoacetonitrilo, proceso para su preparacion, composicion para controlar los parasitos, y uso de estos compuestos para preparar una composicion farmaceutica
US7421660B2 (en) * 2003-02-04 2008-09-02 Cataphora, Inc. Method and apparatus to visually present discussions for data mining purposes
AR039020A1 (es) 2002-03-21 2005-02-02 Novartis Ag Compuestos de aminoacetonitrilo
TW200400004A (en) 2002-05-22 2004-01-01 Novartis Ag Organic compounds
TW200400931A (en) 2002-05-22 2004-01-16 Novartis Ag Organic compounds
AR039961A1 (es) 2002-06-06 2005-03-09 Novartis Ag Derivados de amidoacetonitrilo y su uso como pesticida
TW200406386A (en) * 2002-06-07 2004-05-01 Novartis Ag Organic compounds
TW200400932A (en) 2002-06-19 2004-01-16 Novartis Ag Organic compounds
GB0214117D0 (en) 2002-06-19 2002-07-31 Syngenta Participations Ag N-sulphonylaminoacetonitriles having pesticidal properties
US7001889B2 (en) 2002-06-21 2006-02-21 Merial Limited Anthelmintic oral homogeneous veterinary pastes
AR042420A1 (es) 2002-09-11 2005-06-22 Novartis Ag Benzotriazolil- aminoacetonitril compuestos, proceso para su preparacion, metodo y uso de los mismos en el control de endo- y ecto-parasitos dentro y sobre ganado productor de sangre caliente y animales domesticos y plantas, y en la preparacion de una composicion farmaceutica
BRPI0413540A (pt) 2003-08-14 2006-10-10 Hoffmann La Roche moduladores gabanérgicos
US8627489B2 (en) * 2003-10-31 2014-01-07 Adobe Systems Incorporated Distributed document version control
GB0402677D0 (en) 2003-11-06 2004-03-10 Novartis Ag Organic compounds
AR046757A1 (es) 2003-12-10 2005-12-21 Novartis Ag Amidoacetonitrilos utiles como pesticidas
AU2005217413B2 (en) * 2004-02-20 2011-06-09 Factiva, Inc. Intelligent search and retrieval system and method
TW200613251A (en) 2004-06-10 2006-05-01 Novartis Ag Organic compounds
US7702618B1 (en) * 2004-07-26 2010-04-20 Google Inc. Information retrieval system for archiving multiple document versions
WO2006043654A1 (ja) 2004-10-22 2006-04-27 Nihon Nohyaku Co., Ltd. アセトニトリル誘導体及び有害生物防除剤並びにその使用方法
AU2005303993B2 (en) 2004-11-09 2009-10-29 Elanco Tiergesundheit Ag Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates
US7788237B2 (en) * 2004-12-17 2010-08-31 Microsoft Corporation Method and system for tracking changes in a document
US7593943B2 (en) * 2005-01-14 2009-09-22 Microsoft Corporation Method and system for synchronizing multiple user revisions to a shared object
KR100878824B1 (ko) 2005-04-01 2009-01-14 엘지전자 주식회사 스케일러블 비디오 신호 인코딩 및 디코딩 방법
US20070057967A1 (en) * 2005-07-13 2007-03-15 Armstrong Orin R System and method for the display of versioned documents and amendments
EP1910278A1 (en) 2005-07-25 2008-04-16 Novartis AG Amidonitrile compounds
US8316292B1 (en) * 2005-11-18 2012-11-20 Google Inc. Identifying multiple versions of documents
US20070150433A1 (en) * 2005-12-22 2007-06-28 Mediatek Inc. Method for managing file in version control system
US7809688B2 (en) * 2006-08-04 2010-10-05 Apple Inc. Managing backup of content
US8136292B2 (en) * 2009-11-13 2012-03-20 Wayne Steven Morgan Device and method for support of sheet material

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