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EA200500673A1 - Аморфная форма соли эзомепразола, способ ее получения и фармацевтическая композиция на её основе - Google Patents

Аморфная форма соли эзомепразола, способ ее получения и фармацевтическая композиция на её основе

Info

Publication number
EA200500673A1
EA200500673A1 EA200500673A EA200500673A EA200500673A1 EA 200500673 A1 EA200500673 A1 EA 200500673A1 EA 200500673 A EA200500673 A EA 200500673A EA 200500673 A EA200500673 A EA 200500673A EA 200500673 A1 EA200500673 A1 EA 200500673A1
Authority
EA
Eurasian Patent Office
Prior art keywords
preparation
ezomeprazol
salt
basis
pharmaceutical composition
Prior art date
Application number
EA200500673A
Other languages
English (en)
Inventor
Махавир Сингх Кханна
Бактаватсалан Виджайярагхаван
Мохан Прасад
Ятендра Кумар
Original Assignee
Рэнбакси Лабораториз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рэнбакси Лабораториз Лимитед filed Critical Рэнбакси Лабораториз Лимитед
Publication of EA200500673A1 publication Critical patent/EA200500673A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Изобретение относится к аморфной форме солей (-) энантиомера омепразола, то есть эзомепразола. Изобретение также относится к способу получения аморфных солей и фармацевтическим композициям, включающим аморфные соли эзомепразола.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200500673A 2002-10-22 2003-10-22 Аморфная форма соли эзомепразола, способ ее получения и фармацевтическая композиция на её основе EA200500673A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1057DE2002 2002-10-22
PCT/IB2003/004662 WO2004037253A1 (en) 2002-10-22 2003-10-22 Amorphous form of esomeprazole salts

Publications (1)

Publication Number Publication Date
EA200500673A1 true EA200500673A1 (ru) 2005-12-29

Family

ID=32170658

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200500673A EA200500673A1 (ru) 2002-10-22 2003-10-22 Аморфная форма соли эзомепразола, способ ее получения и фармацевтическая композиция на её основе

Country Status (8)

Country Link
US (2) US20040235903A1 (ru)
EP (1) EP1556043A1 (ru)
CN (1) CN1728997A (ru)
AU (1) AU2003278406A1 (ru)
BR (1) BR0315574A (ru)
EA (1) EA200500673A1 (ru)
NO (1) NO20052474D0 (ru)
WO (1) WO2004037253A1 (ru)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070224260A1 (en) * 2004-04-15 2007-09-27 Dr. Reddy's Laboratories Limited Dosage Form Having Polymorphic Stability
KR20130038949A (ko) 2004-06-24 2013-04-18 아스트라제네카 아베 에소메프라졸 나트륨염의 제조에서 사용하기 위한 결정 변형의 제조를 위한 신규한 방법
ES2246149B1 (es) * 2004-07-02 2007-06-01 Esteve Quimica, S.A. Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion.
CA2591983A1 (en) * 2004-12-20 2006-06-29 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions comprising amorphous benzimidazole compounds
EP1830823A2 (en) 2004-12-23 2007-09-12 Ranbaxy Laboratories Limited Stable oral benzimidazole compositions and process of preparation thereof
DE102005008412A1 (de) * 2005-02-24 2006-09-07 Ratiopharm Gmbh Piperazinsalz des Omeprazols und dessen Enantiomere
EP1856101A4 (en) * 2005-03-08 2009-10-21 Reddys Lab Ltd Dr PROCESS FOR PREPARING AMORPHENE SALTS
WO2007008588A2 (en) * 2005-07-07 2007-01-18 Dr. Reddy's Laboratories Ltd. Omeprazole form b
WO2007031845A2 (en) * 2005-09-14 2007-03-22 Glenmark Pharmaceuticals Limited Polymorphic forms of (s)-omeprazole magnesium salts and processes for their preparation
US20090082572A1 (en) * 2005-11-14 2009-03-26 Hetero Drugs Limited Process for amorphous esomeprazole
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
AU2006323245B2 (en) * 2005-12-05 2011-03-03 Astrazeneca Ab New process for the preparation of esomeprazole non-salt form
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
US7553857B2 (en) * 2005-12-23 2009-06-30 Lek Pharmaceuticals D.D. S-omeprazole magnesium
WO2007142580A1 (en) * 2006-06-07 2007-12-13 Astrazeneca Ab Novel method for preparation of ammonium salts of esomeprazole
EA200900985A1 (ru) 2007-01-31 2009-12-30 Крка, Товарна Здравил, Д. Д., Ново Место Способ получения оптически чистого омепразола
AU2008217603C1 (en) 2007-02-21 2013-08-15 Cipla Limited Process for the preparation of esomeprazole magnesium dihydrate
US8106210B2 (en) * 2007-10-08 2012-01-31 Hetero Drugs Limited Polymorphs of esomeprazole salts
US8911787B2 (en) 2008-02-26 2014-12-16 Ranbaxy Laboratories Limited Stable oral benzimidazole compositions and process of preparation thereof
EP2147918A1 (en) 2008-07-21 2010-01-27 LEK Pharmaceuticals D.D. Process for the preparation of S-omeprazole magnesium in a stable form
WO2010097583A1 (en) * 2009-02-24 2010-09-02 Cipla Limited Esomeprazole potassium polymorph and its preparation
WO2011095984A1 (en) * 2010-02-02 2011-08-11 Glenmark Generics Limited A process for the preparation of amorphous esomeprazole
FR3062129B1 (fr) * 2017-01-23 2019-04-05 Minakem Procede d'obtention du sel de magnesium dihydrate de l'esomeprazole
CN113387929A (zh) * 2021-06-30 2021-09-14 江苏中邦制药有限公司 一种艾司奥美拉唑镁三水合物的制备方法

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SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
US5714505A (en) * 1994-01-05 1998-02-03 Astra Aktiebolag Method for treatment of psoriasis, by omeprazole or related compounds
SE504459C2 (sv) 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
SE510666C2 (sv) * 1996-12-20 1999-06-14 Astra Ab Nya Kristallmodifikationer
SE510650C2 (sv) * 1997-05-30 1999-06-14 Astra Ab Ny förening
SE510643C2 (sv) * 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
US6124816A (en) * 1998-06-02 2000-09-26 Cirrus Logic, Inc. One bit digital to analog converter with relaxed filtering requirements
US6262085B1 (en) * 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
CA2290893C (en) * 1999-11-16 2007-05-01 Bernard Charles Sherman Magnesium omeprazole
BR0110926A (pt) * 2000-05-15 2004-02-17 Ranbaxy Lab Ltd Novas formas amorfas de sais de omeprazol e processo de preparação dos mesmos
WO2002012225A1 (fr) * 2000-08-04 2002-02-14 Takeda Chemical Industries, Ltd. Sels de composé à base de benzimidazole et leurs applications
CA2386716C (en) * 2002-05-17 2012-07-24 Bernard Charles Sherman Magnesium salt of s-omeprazole
IL159854A0 (en) * 2001-07-16 2004-06-20 Janssen Pharmaceutica Nv Improved process for preparing benzimidazole-type compounds
US7169793B2 (en) * 2002-06-27 2007-01-30 Dr. Reddy's Laboratories Limited Process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof
US7651788B2 (en) * 2003-03-05 2010-01-26 Lg Display Co., Ltd. Organic electroluminescent device

Also Published As

Publication number Publication date
EP1556043A1 (en) 2005-07-27
BR0315574A (pt) 2005-09-20
WO2004037253A1 (en) 2004-05-06
US20080119654A1 (en) 2008-05-22
CN1728997A (zh) 2006-02-01
NO20052474L (no) 2005-05-23
US20040235903A1 (en) 2004-11-25
AU2003278406A1 (en) 2004-05-13
NO20052474D0 (no) 2005-05-23
US7482463B2 (en) 2009-01-27

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