EA200400205A1 - Пептиды, эффективные в лечении опухолей и других заболеваний, требующих удаления или разрушения клеток - Google Patents
Пептиды, эффективные в лечении опухолей и других заболеваний, требующих удаления или разрушения клетокInfo
- Publication number
- EA200400205A1 EA200400205A1 EA200400205A EA200400205A EA200400205A1 EA 200400205 A1 EA200400205 A1 EA 200400205A1 EA 200400205 A EA200400205 A EA 200400205A EA 200400205 A EA200400205 A EA 200400205A EA 200400205 A1 EA200400205 A1 EA 200400205A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- destruction
- cells
- tumors
- diseases
- treatment
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Transplantation (AREA)
- Psychiatry (AREA)
Abstract
Данное изобретение посвящено пептидам, композициям и методам лечения заболеваний, например, доброкачественных и злокачественных опухолей, требующих удаления или разрушения вредных или нежелательных клеток у пациента, которому требуется такая терапия; лечение включает использование белков (а также пептидов, произведенных из аминокислотных последовательностей этих белков), аминокислотная последовательность которых включает по крайней мере одну аминокислотную последовательность, произведенную из протеинов нервной нити, и другие родственные молекулы.Отчет о международном поиске был опубликован 2003.11.20.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30615001P | 2001-07-19 | 2001-07-19 | |
US30616101P | 2001-07-19 | 2001-07-19 | |
US33147701P | 2001-11-16 | 2001-11-16 | |
PCT/CA2002/001106 WO2003008444A2 (en) | 2001-07-19 | 2002-07-19 | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200400205A1 true EA200400205A1 (ru) | 2004-06-24 |
EA006603B1 EA006603B1 (ru) | 2006-02-24 |
Family
ID=27405149
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200400205A EA006603B1 (ru) | 2001-07-19 | 2002-07-19 | Пептиды, эффективные в лечении опухолей и других заболеваний, требующих удаления или разрушения клеток |
Country Status (22)
Country | Link |
---|---|
US (2) | US7241738B2 (ru) |
EP (2) | EP1417227B1 (ru) |
JP (4) | JP4587667B2 (ru) |
KR (2) | KR100966232B1 (ru) |
CN (1) | CN100475843C (ru) |
AT (1) | ATE353914T1 (ru) |
AU (2) | AU2002319050B2 (ru) |
BR (2) | BR0211199A (ru) |
CA (2) | CA2453967C (ru) |
CY (1) | CY1108009T1 (ru) |
DE (2) | DE60218179T2 (ru) |
DK (1) | DK1417228T3 (ru) |
EA (1) | EA006603B1 (ru) |
ES (2) | ES2281528T3 (ru) |
IL (2) | IL159903A0 (ru) |
MX (1) | MXPA04000561A (ru) |
NO (1) | NO333999B1 (ru) |
NZ (2) | NZ531114A (ru) |
PL (1) | PL207588B1 (ru) |
PT (1) | PT1417228E (ru) |
WO (2) | WO2003008444A2 (ru) |
ZA (1) | ZA200401320B (ru) |
Families Citing this family (33)
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US20050245451A1 (en) * | 2000-04-05 | 2005-11-03 | Pincus Matthew R | Peptides selectively lethal to malignant and transformed mammalian cells |
AU2002304314B2 (en) * | 2001-03-08 | 2007-09-06 | Nyomox Pharmaceutical Corporation | Using neural thread proteins to treat tumors and other hyperproliferative disorders |
US7271240B2 (en) | 2001-03-14 | 2007-09-18 | Agensys, Inc. | 125P5C8: a tissue specific protein highly expressed in various cancers |
JP4587667B2 (ja) * | 2001-07-19 | 2010-11-24 | ナイモックス コーポレーション | 細胞の除去又は破壊を必要とする腫瘍及び他の状態の治療に有効なペプチド |
US7317077B2 (en) * | 2001-11-16 | 2008-01-08 | Nymox Pharmaceutical Corporation | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
AU2002359572A1 (en) * | 2001-12-04 | 2003-06-17 | Millennium Pharmaceuticals, Inc. | 15603, a human ion channel family member |
WO2005014635A2 (en) * | 2003-07-15 | 2005-02-17 | Genova Ltd. | Secreted polypeptide species reduced in cardiovascular disorders |
BRPI0412664A (pt) * | 2003-07-15 | 2006-09-26 | Ca Nat Research Council | método para tratar uma condição caracterizada por hiperproliferação de células da pele em um indivìduo em risco ou portador dessa condição e utilização de uma quantidade terapeuticamente efetiva de um análogo cìclico de hormÈnio de paratireóide humano (hpth) |
CA2555306A1 (en) * | 2004-02-06 | 2005-08-18 | Nymox Corporation | Humanized antibody |
US20060173490A1 (en) | 2005-02-01 | 2006-08-03 | Boston Scientific Scimed, Inc. | Filter system and method |
BRPI0708340A2 (pt) | 2006-02-28 | 2011-05-24 | Nymox Corp | peptìdio isolado, mimético dele, composição, processo de tratamento de uma condição em um mamìfero requerendo remoção ou destruição de células, e processo de prevenção ou inibição de estenose, oclusão ou bloqueio de um cateter |
AU2007224971A1 (en) * | 2006-03-10 | 2007-09-20 | Nymox Corporation | Method of preventing or reducing the risk or incidence of cancer using neural thread protein based peptides |
US20080027005A1 (en) * | 2006-07-31 | 2008-01-31 | Paul Averback | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
JP5572938B2 (ja) * | 2007-10-25 | 2014-08-20 | 東レ株式会社 | 免疫誘導剤 |
CA2990235C (en) * | 2007-10-25 | 2022-06-14 | Toray Industries, Inc. | Immune response inducer |
EP2224961A1 (en) * | 2007-11-26 | 2010-09-08 | The Research Foundation of the State University of New York | Small molecule cancer treatments that cause necrosis in cancer cells but do not affect normal cells |
AU2009240516B2 (en) * | 2008-04-24 | 2015-06-11 | Therimunex Pharmaceuticals, Inc. | Peptidyl diacylglycerides |
TWI651096B (zh) | 2010-09-29 | 2019-02-21 | 美商艾澤西公司 | 與191p4d12蛋白結合之抗體藥物共軛物(adc) |
CA2928526A1 (en) | 2013-11-01 | 2015-05-07 | Spherium Biomed S.L. | Inclusion bodies for transdermal delivery of therapeutic and cosmetic agents |
US20160215031A1 (en) * | 2015-01-27 | 2016-07-28 | Nymox Pharnaceutical Corporation | Method of treating disorders requiring destruction or removal of cells |
US20160361380A1 (en) * | 2015-06-12 | 2016-12-15 | Nymox Corporation | Combination compositions for treating disorders requiring removal or destruction of unwanted cellular proliferations |
US11628202B2 (en) * | 2015-07-24 | 2023-04-18 | Nymox Corporation | Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia |
US10183058B2 (en) * | 2016-06-17 | 2019-01-22 | Nymox Corporation | Method of preventing or reducing the progression of prostate cancer |
US10172910B2 (en) | 2016-07-28 | 2019-01-08 | Nymox Corporation | Method of preventing or reducing the incidence of acute urinary retention |
US10532081B2 (en) | 2016-09-07 | 2020-01-14 | Nymox Corporation | Method of ameliorating or preventing the worsening or the progression of symptoms of BPH |
US10335453B2 (en) | 2017-03-01 | 2019-07-02 | Nymox Corporation | Compositions and methods for improving sexual function |
US10835538B2 (en) | 2018-03-28 | 2020-11-17 | Nymox Corporation | Method of treating benign prostatic hyperlasia with antibiotics |
US20200061150A1 (en) | 2018-08-23 | 2020-02-27 | Nymox Corporation | Method of inducing selective prostate glandular pharmaco-ablation with sparing of nerves and preservation of sexual function |
US11298400B2 (en) | 2019-05-13 | 2022-04-12 | Nymox Corporation | Method of enhancing the therapeutic efficacy of fexapotide triflutate in treating LUTS |
US11278588B2 (en) | 2019-05-13 | 2022-03-22 | Nymox Corporation | Method of treating lower urinary tract symptoms with fexapotide triflutate |
US20200360466A1 (en) | 2019-05-13 | 2020-11-19 | Nymox Corporation | Method of improving lower urinary tract symptoms |
US11231421B2 (en) | 2019-07-31 | 2022-01-25 | Nymox Corporation | Methods of treating multifocal cancer |
US11331374B2 (en) | 2019-07-31 | 2022-05-17 | Nymox Corporation | Focal treatment of prostate cancer |
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EP1089734A2 (en) * | 1998-06-26 | 2001-04-11 | Georgetown University Medical Center | Use of tempo and tempo derivatives for inducing cell death |
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