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EA199900253A1 - Ptx-чувствительные g-протеины, их получение и применение - Google Patents

Ptx-чувствительные g-протеины, их получение и применение

Info

Publication number
EA199900253A1
EA199900253A1 EA199900253A EA199900253A EA199900253A1 EA 199900253 A1 EA199900253 A1 EA 199900253A1 EA 199900253 A EA199900253 A EA 199900253A EA 199900253 A EA199900253 A EA 199900253A EA 199900253 A1 EA199900253 A1 EA 199900253A1
Authority
EA
Eurasian Patent Office
Prior art keywords
application
ptx
proteins
sensitive
receiving
Prior art date
Application number
EA199900253A
Other languages
English (en)
Inventor
Винфрид Зифферт
Original Assignee
Винфрид Зифферт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Винфрид Зифферт filed Critical Винфрид Зифферт
Publication of EA199900253A1 publication Critical patent/EA199900253A1/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4722G-proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)

Abstract

В заявке описана β3-субъединица человеческого G-протеина, которая включает не более шести мотивов WD-повтора.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900253A 1996-09-13 1997-08-29 Ptx-чувствительные g-протеины, их получение и применение EA199900253A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19637518A DE19637518A1 (de) 1996-09-13 1996-09-13 PTX-sensitive G-Proteine, ihre Herstellung und Verwendung
PCT/EP1997/004709 WO1998011212A1 (de) 1996-09-13 1997-08-29 Ptx-sensitive g-proteine, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
EA199900253A1 true EA199900253A1 (ru) 1999-10-28

Family

ID=7805651

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900253A EA199900253A1 (ru) 1996-09-13 1997-08-29 Ptx-чувствительные g-протеины, их получение и применение

Country Status (22)

Country Link
US (1) US6251853B1 (ru)
EP (1) EP0931145A1 (ru)
JP (1) JP2001501811A (ru)
KR (1) KR20000036058A (ru)
CN (1) CN1230222A (ru)
AU (1) AU4619297A (ru)
BG (1) BG103238A (ru)
BR (1) BR9711475A (ru)
CA (1) CA2265467A1 (ru)
CZ (1) CZ73499A3 (ru)
DE (1) DE19637518A1 (ru)
EA (1) EA199900253A1 (ru)
EE (1) EE9900092A (ru)
HU (1) HUP9904110A3 (ru)
IL (1) IL128746A0 (ru)
IS (1) IS4987A (ru)
NO (1) NO991227L (ru)
PL (1) PL332417A1 (ru)
SK (1) SK34099A3 (ru)
TR (1) TR199900500T2 (ru)
WO (1) WO1998011212A1 (ru)
ZA (1) ZA978220B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19619362A1 (de) * 1996-05-14 1997-11-20 Basf Ag Verwendung einer Genveränderung im Gen für humanes G-Protein beta-3-Untereinheit zur Diagnostik von Erkrankungen
WO1999058669A1 (en) * 1998-05-11 1999-11-18 Axys Pharmaceuticals, Inc. Rhoh genes and their uses
WO2000015785A2 (de) * 1998-09-10 2000-03-23 Winfried Siffert GENVERÄNDERUNG IM GEN FÜR DIE Gβ3-UNTEREINHEIT DES HUMANEN G-PROTEINS
FR2803525B1 (fr) * 2000-01-06 2002-05-03 Sod Conseils Rech Applic Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle
CA2399141A1 (en) * 2000-02-03 2001-08-09 Snip Biotech Gmbh & Co. Kg Use of a mutation in the gene for the .beta.3-subunit of human g-protein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5587561A (en) 1995-07-28 1996-12-24 Budayr; Mahdi Stethoscope shield
DE19619362A1 (de) * 1996-05-14 1997-11-20 Basf Ag Verwendung einer Genveränderung im Gen für humanes G-Protein beta-3-Untereinheit zur Diagnostik von Erkrankungen

Also Published As

Publication number Publication date
BR9711475A (pt) 1999-08-24
BG103238A (bg) 2000-06-30
PL332417A1 (en) 1999-09-13
IS4987A (is) 1999-02-26
NO991227D0 (no) 1999-03-12
AU4619297A (en) 1998-04-02
TR199900500T2 (xx) 1999-06-21
JP2001501811A (ja) 2001-02-13
KR20000036058A (ko) 2000-06-26
CZ73499A3 (cs) 1999-07-14
HUP9904110A2 (en) 2000-07-28
US6251853B1 (en) 2001-06-26
HUP9904110A3 (en) 2001-09-28
WO1998011212A1 (de) 1998-03-19
CN1230222A (zh) 1999-09-29
DE19637518A1 (de) 1998-04-09
SK34099A3 (en) 2000-05-16
EE9900092A (et) 1999-10-15
IL128746A0 (en) 2000-01-31
EP0931145A1 (de) 1999-07-28
NO991227L (no) 1999-03-12
ZA978220B (en) 1999-03-12
CA2265467A1 (en) 1998-03-19

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