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DK498988A - 3,7-diazabicyclooe3,3,1aanonan-forbindelser, fremgangsmaade til deres fremstilling og hjertevirksomme laegemidler indeholdende disse - Google Patents

3,7-diazabicyclooe3,3,1aanonan-forbindelser, fremgangsmaade til deres fremstilling og hjertevirksomme laegemidler indeholdende disse

Info

Publication number
DK498988A
DK498988A DK498988A DK498988A DK498988A DK 498988 A DK498988 A DK 498988A DK 498988 A DK498988 A DK 498988A DK 498988 A DK498988 A DK 498988A DK 498988 A DK498988 A DK 498988A
Authority
DK
Denmark
Prior art keywords
1aanonane
heart
procedures
compounds
production
Prior art date
Application number
DK498988A
Other languages
English (en)
Other versions
DK498988D0 (da
Inventor
Uwe Schoen
Wolfgang Kehrbach
Gerd Buschmann
Ulrich Kuehl
Dieter Ziegler
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19873730222 external-priority patent/DE3730222A1/de
Priority claimed from DE19873730224 external-priority patent/DE3730224A1/de
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of DK498988D0 publication Critical patent/DK498988D0/da
Publication of DK498988A publication Critical patent/DK498988A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK498988A 1987-09-09 1988-09-08 3,7-diazabicyclooe3,3,1aanonan-forbindelser, fremgangsmaade til deres fremstilling og hjertevirksomme laegemidler indeholdende disse DK498988A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873730222 DE3730222A1 (de) 1987-09-09 1987-09-09 3-benzhydryl-3,7-diazabicyclo(3,3,1)nonan- verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE19873730224 DE3730224A1 (de) 1987-09-09 1987-09-09 3-cinnamyl-3,7-diazabicyclo(3,3,1) nonan-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
DK498988D0 DK498988D0 (da) 1988-09-08
DK498988A true DK498988A (da) 1989-03-10

Family

ID=25859590

Family Applications (1)

Application Number Title Priority Date Filing Date
DK498988A DK498988A (da) 1987-09-09 1988-09-08 3,7-diazabicyclooe3,3,1aanonan-forbindelser, fremgangsmaade til deres fremstilling og hjertevirksomme laegemidler indeholdende disse

Country Status (13)

Country Link
US (1) US4912113A (da)
EP (1) EP0306871B1 (da)
JP (1) JPS6468372A (da)
AU (1) AU605904B2 (da)
DE (1) DE3886145D1 (da)
DK (1) DK498988A (da)
ES (1) ES2061580T3 (da)
FI (1) FI884138A (da)
HU (1) HU198718B (da)
IL (1) IL87714A0 (da)
NO (1) NO884008L (da)
NZ (1) NZ226099A (da)
PT (1) PT88381B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4019080A1 (de) * 1990-06-15 1991-12-19 Kali Chemie Pharma Gmbh Neue 3,7-diazabicycolo (3,3,1)nonan-verbindungen enthaltende arzneimittel
DE4139763A1 (de) * 1991-12-03 1993-06-09 Kali-Chemie Pharma Gmbh, 3000 Hannover, De Kristalline fumarsaure salze von 9,9-alkylen-3,7-diazabicyclononan-verbindungen und diese verbindungen enthaltende arzneimittel
DE4402933A1 (de) * 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Benzoyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
SE9902268D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902271D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
US20050004113A1 (en) * 1999-06-16 2005-01-06 Astrazeneca Ab New bispidine compounds useful in the treatment of cardiac arrhythmias
US20040229900A1 (en) * 1999-06-16 2004-11-18 Astrazeneca Ab Bispidine compounds useful in the treatment of cardiac arrythmias
SE9902270D0 (sv) 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902269D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9904765D0 (sv) 1999-12-23 1999-12-23 Astra Ab Pharmaceutically-useful compounds
US6808924B1 (en) 2000-07-11 2004-10-26 Claudia Lanari Mouse mammary tumor lines expressing estrogen and progesterone receptors
SE0003795D0 (sv) 2000-10-20 2000-10-20 Astrazeneca Ab Pharmaceutically useful compounds
SE0100326D0 (sv) 2001-02-02 2001-02-02 Astrazeneca Ab New compounds
DE10131217A1 (de) * 2001-06-28 2003-01-09 Solvay Pharm Gmbh 3-Phenyl-3,7-diazabicyclo 3,3,1 nonan-Verbindungen sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
TW200418468A (en) * 2002-11-18 2004-10-01 Solvay Pharm Gmbh Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events
BRPI0412247A (pt) * 2003-07-21 2006-09-19 Solvay Pharm Gmbh uso de compostos 3,7-diazabiciclo[3.3.1]nonano para o tratamento e/ou profilaxia de episódios arrìtmicos em doentes humanos do sexo masculino
US20050054667A1 (en) * 2003-07-21 2005-03-10 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting anti-arrhythmic events in male human patients
SE0401540D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
SE0401539D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
US7928225B2 (en) 2005-06-13 2011-04-19 Astrazeneca Ab Oxabispidine compounds for the treatment of cardiac arrhythmias

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428792A1 (de) * 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE2658558A1 (de) * 1976-12-23 1978-06-29 Bayer Ag Diazabicyclo(3,3,1)nonane, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2726571A1 (de) * 1977-06-13 1978-12-21 Basf Ag Neue bispidinderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane

Also Published As

Publication number Publication date
FI884138A0 (fi) 1988-09-08
DE3886145D1 (de) 1994-01-20
AU2200588A (en) 1989-03-23
PT88381A (pt) 1989-06-30
US4912113A (en) 1990-03-27
PT88381B (pt) 1995-07-06
JPS6468372A (en) 1989-03-14
NO884008D0 (no) 1988-09-08
EP0306871A2 (de) 1989-03-15
FI884138A (fi) 1989-03-10
NZ226099A (en) 1990-07-26
AU605904B2 (en) 1991-01-24
HUT48248A (en) 1989-05-29
IL87714A0 (en) 1989-02-28
DK498988D0 (da) 1988-09-08
EP0306871A3 (en) 1990-08-01
EP0306871B1 (de) 1993-12-08
NO884008L (no) 1989-03-10
ES2061580T3 (es) 1994-12-16
HU198718B (en) 1989-11-28

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