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DK3680243T3 - Pentacyklisk forbindelse - Google Patents

Pentacyklisk forbindelse Download PDF

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Publication number
DK3680243T3
DK3680243T3 DK18853415.0T DK18853415T DK3680243T3 DK 3680243 T3 DK3680243 T3 DK 3680243T3 DK 18853415 T DK18853415 T DK 18853415T DK 3680243 T3 DK3680243 T3 DK 3680243T3
Authority
DK
Denmark
Prior art keywords
pentacyclic
connection
pentacyclic connection
Prior art date
Application number
DK18853415.0T
Other languages
English (en)
Inventor
Yoshiaki Ohashi
Yoshihiko Norimine
Tamaki HOSHIKAWA
Yu Yoshida
Yoshihisa Kobayashi
Nobuhiro Sato
Koji Hagiwara
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Application granted granted Critical
Publication of DK3680243T3 publication Critical patent/DK3680243T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK18853415.0T 2017-09-07 2018-09-05 Pentacyklisk forbindelse DK3680243T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017172169 2017-09-07
PCT/JP2018/032797 WO2019049869A1 (ja) 2017-09-07 2018-09-05 五環式化合物

Publications (1)

Publication Number Publication Date
DK3680243T3 true DK3680243T3 (da) 2022-01-10

Family

ID=65517037

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18853415.0T DK3680243T3 (da) 2017-09-07 2018-09-05 Pentacyklisk forbindelse

Country Status (35)

Country Link
US (1) US10239889B1 (da)
EP (1) EP3680243B1 (da)
JP (1) JP6557441B1 (da)
KR (1) KR102307738B1 (da)
CN (1) CN111051316B (da)
AR (1) AR112788A1 (da)
AU (1) AU2018330578B2 (da)
BR (1) BR112020003197A2 (da)
CA (1) CA3072740A1 (da)
CL (1) CL2020000376A1 (da)
CO (1) CO2020001471A2 (da)
CY (1) CY1125355T1 (da)
DK (1) DK3680243T3 (da)
ES (1) ES2903172T3 (da)
HR (1) HRP20220019T1 (da)
HU (1) HUE056791T2 (da)
IL (1) IL272652B (da)
JO (1) JOP20200030A1 (da)
LT (1) LT3680243T (da)
MA (1) MA50093B1 (da)
MD (1) MD3680243T2 (da)
MX (1) MX2020001786A (da)
PE (1) PE20200860A1 (da)
PH (1) PH12020500341A1 (da)
PL (1) PL3680243T3 (da)
PT (1) PT3680243T (da)
RS (1) RS62796B1 (da)
RU (1) RU2754557C1 (da)
SG (1) SG11202001240XA (da)
SI (1) SI3680243T1 (da)
SM (1) SMT202200004T1 (da)
TW (1) TWI707859B (da)
UA (1) UA125940C2 (da)
WO (1) WO2019049869A1 (da)
ZA (2) ZA202000970B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL318939A (en) 2017-09-07 2025-04-01 Univ Res Inst Inc Augusta Specific AKT3 activator and its uses
CN109467538A (zh) 2017-09-07 2019-03-15 和记黄埔医药(上海)有限公司 环烯烃取代的杂芳环类化合物及其用途
AU2020232044B2 (en) * 2019-03-05 2025-02-20 Eisai R&D Management Co., Ltd. Pentacyclic heterocyclic compound
AU2020233452B2 (en) * 2019-03-05 2025-04-10 Eisai R&D Management Co., Ltd. Salt of pentacyclic compound and crystals thereof
US20230101747A1 (en) * 2019-12-06 2023-03-30 Schrödinger, Inc. Cyclic compounds and methods of using same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4187306A (en) * 1977-07-26 1980-02-05 Bayer Aktiengesellschaft Benzodiazepine-diones, a process for their production and their use as medicaments
DD258234A1 (de) * 1987-03-05 1988-07-13 Univ Leipzig Verfahren zur herstellung von pyrido/3',2':4,5/thieno/2,3-e/imidazo-/1,2-c/pyrimidinen sowie strukturanaloger -pyrimido/1,2-c/pyrimidine bzw. -1,3-diazepino/1,2-c/pyrimidine
RU2117670C1 (ru) * 1988-10-31 1998-08-20 Эйсай Ко., Лтд. Производные триазоло[1,4]диазепина и способы их получения
TW197442B (da) * 1990-02-08 1993-01-01 Pfizer
KR100203456B1 (ko) * 1995-06-20 1999-06-15 한승수 디하이드로에보디아민-에이치씨1를 유효성분으로 함유하는 알츠하이머병에 의한 치매 치료제
FR2779652B1 (fr) * 1998-06-15 2001-06-08 Sod Conseils Rech Applic Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique
WO2006045429A1 (en) * 2004-10-20 2006-05-04 F. Hoffmann-La Roche Ag Halogen substituted benzodiazepine derivatives
JP2009184924A (ja) 2006-05-31 2009-08-20 Eisai R & D Management Co Ltd 生物学的試薬用化合物

Also Published As

Publication number Publication date
MD3680243T2 (ro) 2022-05-31
HRP20220019T1 (hr) 2022-04-01
ZA202007737B (en) 2025-04-30
CL2020000376A1 (es) 2020-08-28
PL3680243T3 (pl) 2022-02-14
PT3680243T (pt) 2022-01-12
PE20200860A1 (es) 2020-08-25
CO2020001471A2 (es) 2020-05-29
SG11202001240XA (en) 2020-03-30
TW201920195A (zh) 2019-06-01
RS62796B1 (sr) 2022-02-28
ZA202000970B (en) 2021-07-28
CY1125355T1 (el) 2024-02-16
ES2903172T3 (es) 2022-03-31
AU2018330578B2 (en) 2022-11-10
JOP20200030A1 (ar) 2020-02-12
CN111051316B (zh) 2022-05-31
BR112020003197A2 (pt) 2020-09-29
US20190071452A1 (en) 2019-03-07
CN111051316A (zh) 2020-04-21
KR20200051585A (ko) 2020-05-13
MX2020001786A (es) 2022-09-13
SMT202200004T1 (it) 2022-03-21
EP3680243A4 (en) 2021-01-06
JP6557441B1 (ja) 2019-08-07
IL272652A (en) 2020-03-31
PH12020500341A1 (en) 2020-10-05
TWI707859B (zh) 2020-10-21
AR112788A1 (es) 2019-12-11
SI3680243T1 (sl) 2022-01-31
EP3680243B1 (en) 2021-10-27
EP3680243A1 (en) 2020-07-15
MA50093B1 (fr) 2022-05-31
MA50093A (fr) 2021-05-05
IL272652B (en) 2022-09-01
WO2019049869A1 (ja) 2019-03-14
JPWO2019049869A1 (ja) 2019-11-07
US10239889B1 (en) 2019-03-26
KR102307738B1 (ko) 2021-10-05
HUE056791T2 (hu) 2022-03-28
LT3680243T (lt) 2021-11-25
UA125940C2 (uk) 2022-07-13
AU2018330578A1 (en) 2020-02-27
CA3072740A1 (en) 2019-03-14
RU2754557C1 (ru) 2021-09-03

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