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DK3436047T3 - Duale Ace-C-Domain-inhibitorer - Google Patents

Duale Ace-C-Domain-inhibitorer Download PDF

Info

Publication number
DK3436047T3
DK3436047T3 DK17716015.7T DK17716015T DK3436047T3 DK 3436047 T3 DK3436047 T3 DK 3436047T3 DK 17716015 T DK17716015 T DK 17716015T DK 3436047 T3 DK3436047 T3 DK 3436047T3
Authority
DK
Denmark
Prior art keywords
domain inhibitors
dual ace
ace
dual
inhibitors
Prior art date
Application number
DK17716015.7T
Other languages
English (en)
Inventor
Edward D Sturrock
Mario R W Ehlers
Original Assignee
Angiodesign Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiodesign Uk Ltd filed Critical Angiodesign Uk Ltd
Application granted granted Critical
Publication of DK3436047T3 publication Critical patent/DK3436047T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035Isoindoles, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK17716015.7T 2016-04-01 2017-03-31 Duale Ace-C-Domain-inhibitorer DK3436047T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201605602 2016-04-01
PCT/IB2017/051856 WO2017168383A1 (en) 2016-04-01 2017-03-31 Dual ace c-domain/nep inhibitors

Publications (1)

Publication Number Publication Date
DK3436047T3 true DK3436047T3 (da) 2024-05-06

Family

ID=58489751

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17716015.7T DK3436047T3 (da) 2016-04-01 2017-03-31 Duale Ace-C-Domain-inhibitorer

Country Status (5)

Country Link
US (1) US11129805B2 (da)
EP (1) EP3436047B1 (da)
CA (1) CA3019462A1 (da)
DK (1) DK3436047T3 (da)
WO (1) WO2017168383A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL303494A (en) * 2020-12-10 2023-08-01 Baropace Inc Treatment of drug-resistant hypertension and heart failure with ejection fraction preservation by combined treatment BAROPACING and beta blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002087621A1 (en) * 2001-04-30 2002-11-07 Shire Laboratories Inc. Pharmaceutical composition including ace/nep inhibitors and bioavailability enhancers

Also Published As

Publication number Publication date
CA3019462A1 (en) 2017-10-05
US11129805B2 (en) 2021-09-28
EP3436047A1 (en) 2019-02-06
WO2017168383A1 (en) 2017-10-05
EP3436047B1 (en) 2024-04-24
US20190111014A1 (en) 2019-04-18

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