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DK3429577T3 - N-lipoinaminosyre eller peptid, derivater og anvendelser deraf - Google Patents

N-lipoinaminosyre eller peptid, derivater og anvendelser deraf Download PDF

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Publication number
DK3429577T3
DK3429577T3 DK16894728.1T DK16894728T DK3429577T3 DK 3429577 T3 DK3429577 T3 DK 3429577T3 DK 16894728 T DK16894728 T DK 16894728T DK 3429577 T3 DK3429577 T3 DK 3429577T3
Authority
DK
Denmark
Prior art keywords
lipoinamino
peptide
derivatives
acid
lipoinamino acid
Prior art date
Application number
DK16894728.1T
Other languages
English (en)
Inventor
Ruey J Yu
Scott Eugene J Van
Original Assignee
Neostrata Company Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neostrata Company Inc filed Critical Neostrata Company Inc
Application granted granted Critical
Publication of DK3429577T3 publication Critical patent/DK3429577T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/04Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Immunology (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK16894728.1T 2016-03-14 2016-03-14 N-lipoinaminosyre eller peptid, derivater og anvendelser deraf DK3429577T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2016/022289 WO2017160269A1 (en) 2016-03-14 2016-03-14 N-lipoic -amino acid or peptide, derivatives and their uses

Publications (1)

Publication Number Publication Date
DK3429577T3 true DK3429577T3 (da) 2022-03-07

Family

ID=59850403

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16894728.1T DK3429577T3 (da) 2016-03-14 2016-03-14 N-lipoinaminosyre eller peptid, derivater og anvendelser deraf

Country Status (13)

Country Link
US (1) US11155531B2 (da)
EP (2) EP4018997A1 (da)
JP (1) JP6858837B2 (da)
KR (1) KR102626973B1 (da)
CN (1) CN109152757A (da)
AU (1) AU2016397562B2 (da)
BR (1) BR112018068456A2 (da)
CA (1) CA3017449C (da)
DK (1) DK3429577T3 (da)
ES (1) ES2906178T3 (da)
MX (1) MX2018011082A (da)
RU (1) RU2737377C2 (da)
WO (1) WO2017160269A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220127242A1 (en) * 2016-03-14 2022-04-28 Neostrata Company, Inc. N-lipoic-amino acid or peptide, derivatives and their uses
WO2023283256A1 (en) 2021-07-09 2023-01-12 Aligos Therapeutics, Inc. Anti-viral compounds
US12065428B2 (en) 2021-09-17 2024-08-20 Aligos Therapeutics, Inc. Anti-viral compounds
KR102404228B1 (ko) * 2022-02-18 2022-05-31 주식회사 차메디텍 항산화 효과를 증대시키는 환원된 리포익산-펩타이드 유도체를 포함하는 조성물 및 이의 제조 방법

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63107071A (ja) * 1986-10-23 1988-05-12 Nec Corp 電界効果トランジスタの製造方法
AU728488B2 (en) 1997-04-02 2001-01-11 Sankyo Company Limited Dithiolan derivatives, their preparation and their therapeutic effect
JPH11269170A (ja) * 1997-04-02 1999-10-05 Sankyo Co Ltd ジチオラン誘導体
US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
PT1294353E (pt) 2000-06-06 2006-07-31 Basf Ag Utilizacao do enantiomero (r) do acido lipoico em composicoes cosmeticas e dermatologicas
JP4259813B2 (ja) 2001-05-29 2009-04-30 千寿製薬株式会社 α−リポイルアミノ酸の安定化法および安定化されたα−リポイルアミノ酸を含有する水性液剤
JP2003286168A (ja) * 2002-03-28 2003-10-07 Senju Pharmaceut Co Ltd α−リポイルアミノ酸を含有する皮膚外用剤
WO2003084532A1 (en) 2002-04-03 2003-10-16 Avery Mitchell A Lipoic acid analogs useful as provitamins and antioxidants
FR2870242B1 (fr) 2004-05-11 2010-08-20 Inst Europeen Biologie Cellulaire Peptides ou conjugues peptidiques derives de la msh et leur utilisation dans le traitement cosmetique de la canitie.
FR2870244B1 (fr) * 2004-05-11 2011-01-07 Centre Nat Rech Scient Conjugues dipeptidiques antagonistes de l'alpha-msh
JP2006022066A (ja) * 2004-07-09 2006-01-26 Shiseido Co Ltd 重合抑制剤および即時型黒化防止用皮膚外用剤
US7776915B2 (en) * 2005-03-24 2010-08-17 Tracie Martyn International, Llc Topical formulations and methods of use
GB0605295D0 (en) * 2006-03-16 2006-04-26 Proximagen Ltd Amino and derivatives
WO2009003284A1 (en) 2007-06-29 2009-01-08 Innovactiv Inc. Novel peptides, use thereof in cosmetic and cosmeceutic applications, and compositions comprising same
WO2009020317A2 (en) 2007-08-06 2009-02-12 Biogenics, Inc. Stabilized antioxidant particles, composition comprising the same and method for preparing the same
WO2010045575A2 (en) 2008-10-17 2010-04-22 Invasc Therapeutics, Inc. Compositions and methods for treatment of renin-angiotensin aldosterone system (raas)-related disorders
WO2011044138A1 (en) 2009-10-05 2011-04-14 Catabasis Pharmaceuticals, Inc. Lipoic acid acylated salicylate derivatives and their uses
JP2011195516A (ja) * 2010-03-19 2011-10-06 Oita Univ 制がん剤
CA2817362C (en) * 2010-11-18 2018-10-23 Ischemix Llc Lipoyl compounds and their use for treating ischemic injury
DK3777876T3 (da) 2011-10-28 2023-10-30 Neostrata Company Inc N-acyldipeptid-derivater og anvendelser deraf
US20150329519A1 (en) 2014-05-14 2015-11-19 Ischemix, LLC Formulations Comprising Lipoyl Compounds
JP6271346B2 (ja) 2014-06-12 2018-01-31 アトムメディカル株式会社 ガス類供給用マスク装置

Also Published As

Publication number Publication date
JP2019508506A (ja) 2019-03-28
US11155531B2 (en) 2021-10-26
AU2016397562A1 (en) 2018-09-27
US20190161467A1 (en) 2019-05-30
CA3017449C (en) 2023-09-19
BR112018068456A2 (pt) 2019-01-22
RU2018136108A (ru) 2020-04-15
KR102626973B1 (ko) 2024-01-22
MX2018011082A (es) 2019-03-28
EP3429577A4 (en) 2019-11-06
CA3017449A1 (en) 2017-09-21
EP3429577A1 (en) 2019-01-23
AU2016397562B2 (en) 2023-06-29
JP6858837B2 (ja) 2021-04-14
KR20180120769A (ko) 2018-11-06
EP3429577B1 (en) 2021-12-29
ES2906178T3 (es) 2022-04-13
WO2017160269A1 (en) 2017-09-21
RU2737377C2 (ru) 2020-11-27
CN109152757A (zh) 2019-01-04
EP4018997A1 (en) 2022-06-29
RU2018136108A3 (da) 2020-04-15

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