DK3415157T3 - N-acyldipeptidderivater og anvendelser deraf - Google Patents
N-acyldipeptidderivater og anvendelser deraf Download PDFInfo
- Publication number
- DK3415157T3 DK3415157T3 DK18186827.4T DK18186827T DK3415157T3 DK 3415157 T3 DK3415157 T3 DK 3415157T3 DK 18186827 T DK18186827 T DK 18186827T DK 3415157 T3 DK3415157 T3 DK 3415157T3
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- DK
- Denmark
- Prior art keywords
- acyldipeptide derivatives
- acyldipeptide
- derivatives
- Prior art date
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161552751P | 2011-10-28 | 2011-10-28 | |
US201161554724P | 2011-11-02 | 2011-11-02 | |
US201261582675P | 2012-01-03 | 2012-01-03 | |
EP17180167.3A EP3248609B1 (en) | 2011-10-28 | 2012-10-31 | N-acyldipeptide derivatives and their uses |
Publications (1)
Publication Number | Publication Date |
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DK3415157T3 true DK3415157T3 (da) | 2020-10-19 |
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DK18186827.4T DK3415157T3 (da) | 2011-10-28 | 2012-10-31 | N-acyldipeptidderivater og anvendelser deraf |
DK20196112.5T DK3777876T3 (da) | 2011-10-28 | 2012-10-31 | N-acyldipeptid-derivater og anvendelser deraf |
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DK20196112.5T DK3777876T3 (da) | 2011-10-28 | 2012-10-31 | N-acyldipeptid-derivater og anvendelser deraf |
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US (6) | US9067969B2 (da) |
EP (4) | EP3777876B1 (da) |
JP (1) | JP2015505297A (da) |
AU (4) | AU2012328449B2 (da) |
CA (1) | CA2853791C (da) |
DK (2) | DK3415157T3 (da) |
ES (4) | ES2641438T3 (da) |
FI (1) | FI3777876T3 (da) |
HK (1) | HK1198433A1 (da) |
MX (2) | MX358016B (da) |
WO (1) | WO2013063615A2 (da) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2641438T3 (es) | 2011-10-28 | 2017-11-10 | Neostrata Company, Inc. | Derivados de N-acildipeptida y sus usos |
US9801848B2 (en) | 2013-03-13 | 2017-10-31 | The Regents Of The University Of California | Prevention of rosacea inflammation |
KR101553637B1 (ko) * | 2014-01-27 | 2015-09-16 | (주)셀인바이오 | 펩타이드 지방산 유도체 및 이를 함유하는 주름 개선용 화장품 조성물 |
JP2016027034A (ja) * | 2014-06-30 | 2016-02-18 | ロート製薬株式会社 | 外用組成物 |
US10835572B2 (en) | 2014-06-30 | 2020-11-17 | Rohto Pharmaceutical Co., Ltd. | Composition for external application |
CN115957294A (zh) | 2015-05-28 | 2023-04-14 | 贝勒医学院 | 补充n-乙酰半胱氨酸和甘氨酸以改善谷胱甘肽水平的有益效果 |
MX2018007636A (es) | 2015-12-24 | 2018-09-21 | Unilever Nv | Inhibidores de tirosinasa. |
ES2906178T3 (es) * | 2016-03-14 | 2022-04-13 | Neostrata Company Inc | Aminoácido o péptido N-lipoico, derivados y sus usos |
EP3440051B1 (en) * | 2016-04-04 | 2024-03-20 | Research Triangle Institute | Neuropeptide s receptor (npsr) agonists |
EP3668551A4 (en) * | 2017-08-15 | 2021-04-14 | Children's Medical Center Corporation | APOM FC FUSION PROTEINS AND USES THEREOF |
JP6527996B2 (ja) * | 2017-09-12 | 2019-06-12 | 株式会社 金冠堂 | Fgf活性に影響を与えるジペプチド |
EA202091213A1 (ru) | 2017-11-14 | 2020-08-13 | Юнилевер Н.В. | Пептиды для повышения содержания меланина в меланоцитах |
EA202091390A1 (ru) | 2017-12-06 | 2020-09-04 | Юнилевер Н.В. | Композиция для потемнения кожи |
US20210363181A1 (en) * | 2018-02-08 | 2021-11-25 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Dopamine precursors |
JP2021524454A (ja) * | 2018-05-24 | 2021-09-13 | ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. | プロリン誘導体の新規の使用 |
EP3882256A4 (en) * | 2018-11-12 | 2022-08-10 | CJ Cheiljedang Corporation | METHOD FOR PRODUCTION OF N-ACETYL DIPEPTIDE AND N-ACETYL AMINO ACID |
CN110041300A (zh) * | 2019-02-18 | 2019-07-23 | 海南大学 | 一种医药中间体化合物及其合成方法 |
US20200405609A1 (en) * | 2019-06-26 | 2020-12-31 | Johnson & Johnson Consumer Inc. | Topical compositions containing n-acyl dipeptide derivatives and glycolic acid |
US11400043B2 (en) | 2019-12-10 | 2022-08-02 | Mary Kay Inc. | Cosmetic composition |
AU2022253591A1 (en) | 2021-04-09 | 2023-10-19 | Johnson & Johnson Consumer Inc. | Method of determining the effectiveness of a treatment on a face |
US20230100243A1 (en) * | 2021-08-31 | 2023-03-30 | The Florida International University Board Of Trustees | Peptidomimetics and method of synthesis thereof |
EP4401555A1 (en) * | 2021-09-15 | 2024-07-24 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd | Antimicrobial peptides |
WO2023194400A1 (en) * | 2022-04-06 | 2023-10-12 | Mc2 Therapeutics Ltd | Topical formulation for use in the treatment or prevention of itchy dry skin |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1340120C (en) * | 1986-12-23 | 1998-11-10 | Eugene J. Van Scott | Hydroxyacids for topical treatment of wrinkles and skin changes associated with aging |
US5002760A (en) | 1989-10-02 | 1991-03-26 | Katzev Phillip K | Retinol skin care composition |
DE4022267C2 (de) * | 1990-07-12 | 1994-09-15 | Degussa | N-Acyldipeptide und deren Verwendung |
JPH05170636A (ja) | 1991-12-25 | 1993-07-09 | Narisu Keshohin:Kk | 美白化粧料 |
FR2715565B1 (fr) | 1994-01-31 | 1996-03-15 | Oreal | Composition cosmétique ou dermatologique stabilisée contenant plusieurs précurseurs d'un même actif pour maximaliser sa libération, son utilisation. |
US5688489A (en) * | 1995-09-15 | 1997-11-18 | Resolution Pharmaceuticals, Inc. | Non-receptor mediated imaging agents |
FR2776188B1 (fr) * | 1998-03-20 | 2000-06-16 | Fabre Pierre Dermo Cosmetique | Oleamide de glycylglycine en dermo-cosmetologie |
US7498310B1 (en) * | 1998-08-13 | 2009-03-03 | Beiersdorf Ag | Cosmetic or dermatological preparations comprising oligopeptides for lightening the skin of age marks and/or for preventing tanning of the skin, in particular tanning of the skin caused by UV radiation |
FR2783169B1 (fr) * | 1998-09-15 | 2001-11-02 | Sederma Sa | Utilisation cosmetique ou dermopharmaceutique de peptides pour la cicatrisation et pour l'amelioration de l'aspect cutane lors du vieillissement naturel ou accelere (heliodermie, pollution) |
US6159485A (en) | 1999-01-08 | 2000-12-12 | Yugenic Limited Partnership | N-acetyl aldosamines, n-acetylamino acids and related n-acetyl compounds and their topical use |
US20040022838A1 (en) | 2001-06-20 | 2004-02-05 | Holick Michael F. | Regulation of cell proliferation and differentiation using topically applied peptides |
US20030194445A1 (en) | 2001-11-12 | 2003-10-16 | Kuhner Carla H. | Compositions and methods of use of peptides in combination with biocides and/or germicides |
US7781396B2 (en) * | 2002-01-31 | 2010-08-24 | Tel Aviv University Future Technology Development L.P. | Peptides directed for diagnosis and treatment of amyloid-associated disease |
CA2498354C (en) | 2002-09-11 | 2012-03-20 | Temple University - Of The Commonwealth System Of Higher Education | System and methods for electrophoretic separation of proteins on protein binding membranes |
US7141544B2 (en) * | 2003-10-10 | 2006-11-28 | Baxter International, Inc. | Stabilization of pharmaceutical protein formulations with small peptides |
FR2870244B1 (fr) | 2004-05-11 | 2011-01-07 | Centre Nat Rech Scient | Conjugues dipeptidiques antagonistes de l'alpha-msh |
US20070020220A1 (en) * | 2005-04-27 | 2007-01-25 | Procter & Gamble | Personal care compositions |
FR2894144B1 (fr) * | 2005-12-05 | 2009-05-15 | Oreal | Utilisation du dipeptide tyrosine-arginine dans une composition cosmetique ou pour la preparation d'un medicament |
US7807625B2 (en) * | 2006-01-18 | 2010-10-05 | Grant Industries, Inc | Anti-wrinkle composition |
KR101552453B1 (ko) * | 2006-06-01 | 2015-09-11 | 데라퓨틱 펩타이즈, 인코포레이션 | 중합성 생계면활성제 |
WO2009049172A1 (en) * | 2007-10-10 | 2009-04-16 | Therametics, Llc | Methods and compositions for treating dermatological diseases and conditions |
JP5789901B2 (ja) | 2008-05-29 | 2015-10-07 | セラピューティック・ペプタイズ・インコーポレーテッドTherapeutic Peptides,Inc. | 皮膚化粧用組成物におけるオリゴマーバイオサーファクタント |
ES2356883B1 (es) | 2008-07-24 | 2012-02-22 | Bcn Peptides, S.A. | Composición para el tratamiento del dolor y/o la inflamación. |
US20100114275A1 (en) * | 2008-10-30 | 2010-05-06 | Pacesetter, Inc. | Implantable medical lead including winding for improved mri safety |
US8901083B2 (en) | 2008-11-25 | 2014-12-02 | Temple University | Administration of angiocidin for the treatment of leukemia |
KR101080271B1 (ko) * | 2009-03-31 | 2011-11-08 | 주식회사 웰스킨 | 다이펩타이드를 유효성분으로 포함하는 자외선에 의한 홍반반응 억제용 화장품 조성물 |
KR20100127948A (ko) | 2009-05-27 | 2010-12-07 | 한국전자통신연구원 | Sars 코로나바이러스의 검출 및 억제용 펩타이드 화합물 및 그의 응용 |
EP2727935A3 (en) | 2009-07-14 | 2014-07-30 | Temple University Of The Commonwealth System Of Higher Education | Serum markers associated with early and other stages of breast cancer |
GB0918579D0 (en) * | 2009-10-22 | 2009-12-09 | Imp Innovations Ltd | Gadd45beta targeting agents |
ES2641438T3 (es) | 2011-10-28 | 2017-11-10 | Neostrata Company, Inc. | Derivados de N-acildipeptida y sus usos |
CA2859915A1 (en) | 2012-01-03 | 2013-07-11 | Ruey J. Yu | N-acylpeptide derivatives and their uses |
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2012
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- 2012-10-31 DK DK18186827.4T patent/DK3415157T3/da active
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