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DK3344655T5 - Brug af anti-cd40-antistoffer til behandling af lupus nefritis - Google Patents

Brug af anti-cd40-antistoffer til behandling af lupus nefritis Download PDF

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Publication number
DK3344655T5
DK3344655T5 DK16763663.8T DK16763663T DK3344655T5 DK 3344655 T5 DK3344655 T5 DK 3344655T5 DK 16763663 T DK16763663 T DK 16763663T DK 3344655 T5 DK3344655 T5 DK 3344655T5
Authority
DK
Denmark
Prior art keywords
antibodies
treatment
lupus nephritis
nephritis
lupus
Prior art date
Application number
DK16763663.8T
Other languages
English (en)
Other versions
DK3344655T3 (da
Inventor
Scott Ronald Brodeur
Thomas B Freeman
Gerald Henry Nabozny
Meera RAMANUJAM
Paul Scholl
Juergen STEFFGEN
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of DK3344655T3 publication Critical patent/DK3344655T3/da
Application granted granted Critical
Publication of DK3344655T5 publication Critical patent/DK3344655T5/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71Decreased effector function due to an Fc-modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK16763663.8T 2015-09-01 2016-08-31 Brug af anti-cd40-antistoffer til behandling af lupus nefritis DK3344655T5 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562212810P 2015-09-01 2015-09-01
US201562257336P 2015-11-19 2015-11-19
US201662287587P 2016-01-27 2016-01-27
PCT/US2016/049558 WO2017040566A1 (en) 2015-09-01 2016-08-31 Use of anti-cd40 antibodies for treatment of lupus nephritis

Publications (2)

Publication Number Publication Date
DK3344655T3 DK3344655T3 (da) 2023-10-09
DK3344655T5 true DK3344655T5 (da) 2024-10-07

Family

ID=56896810

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16763663.8T DK3344655T5 (da) 2015-09-01 2016-08-31 Brug af anti-cd40-antistoffer til behandling af lupus nefritis

Country Status (16)

Country Link
US (3) US20170058038A1 (da)
EP (1) EP3344655B1 (da)
JP (2) JP2018529661A (da)
KR (1) KR20180039172A (da)
CN (1) CN107922501A (da)
AU (1) AU2016317028B2 (da)
BR (1) BR112018001907A2 (da)
CA (1) CA2993996A1 (da)
CL (1) CL2018000317A1 (da)
DK (1) DK3344655T5 (da)
ES (1) ES2969968T3 (da)
HU (1) HUE063528T2 (da)
MX (1) MX2018002447A (da)
PH (1) PH12018500445A1 (da)
PL (1) PL3344655T3 (da)
WO (1) WO2017040566A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3026477A1 (en) 2016-06-20 2017-12-28 Kymab Limited Anti-pd-l1 antibodies
CA3101469A1 (en) * 2018-06-29 2020-01-02 Boehringer Ingelheim International Gmbh Anti-cd40 antibodies for use in treating autoimmune disease
TW202021620A (zh) * 2018-11-30 2020-06-16 大陸商江蘇恒瑞醫藥股份有限公司 一種cd40抗體藥物組合物及其用途
AU2022214319A1 (en) 2021-01-28 2023-08-03 Regeneron Pharmaceuticals, Inc. Compositions and methods for treating cytokine release syndrome

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
DE3675588D1 (de) 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
EP0940468A1 (en) 1991-06-14 1999-09-08 Genentech, Inc. Humanized antibody variable domain
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
EP0656789B1 (en) 1992-08-21 1997-12-17 Genentech, Inc. Method for treating a lfa-1-mediated disorder
US6037454A (en) 1996-11-27 2000-03-14 Genentech, Inc. Humanized anti-CD11a antibodies
US20030059427A1 (en) * 2000-04-28 2003-03-27 Force Walker R. Isolation and characterization of highly active anti-CD40 antibody
US8277810B2 (en) * 2003-11-04 2012-10-02 Novartis Vaccines & Diagnostics, Inc. Antagonist anti-CD40 antibodies
MXPA06012430A (es) * 2004-04-27 2007-04-19 Novartis Vaccines & Diagnostic Anticuerpos monoclonales antagonistas anti-cd40 y metodos para su uso.
CN101237882B (zh) * 2005-05-26 2012-08-15 西雅图基因公司 人源化的抗-cd40抗体及其使用方法
MX2008013508A (es) * 2006-04-21 2008-10-31 Novartis Ag Composiciones farmaceuticas de anticuerpos antagonistas anti-cd40.
DK3178851T3 (da) * 2010-03-31 2020-07-27 Boehringer Ingelheim Int Anti-cd40-antistoffer
JP6125489B2 (ja) * 2011-04-29 2017-05-10 アペクシジェン, インコーポレイテッド 抗cd40抗体および使用方法
US20140004131A1 (en) * 2012-05-04 2014-01-02 Novartis Ag Antibody formulation

Also Published As

Publication number Publication date
ES2969968T3 (es) 2024-05-23
EP3344655B1 (en) 2023-07-26
KR20180039172A (ko) 2018-04-17
HUE063528T2 (hu) 2024-01-28
PH12018500445A1 (en) 2018-09-10
DK3344655T3 (da) 2023-10-09
AU2016317028A1 (en) 2018-02-22
CL2018000317A1 (es) 2018-07-20
EP3344655A1 (en) 2018-07-11
JP2018529661A (ja) 2018-10-11
US20170058038A1 (en) 2017-03-02
US20230265203A1 (en) 2023-08-24
MX2018002447A (es) 2018-06-15
US20190177420A1 (en) 2019-06-13
PL3344655T3 (pl) 2024-02-19
AU2016317028B2 (en) 2021-09-09
CA2993996A1 (en) 2017-03-09
BR112018001907A2 (pt) 2018-09-25
WO2017040566A1 (en) 2017-03-09
JP2021185169A (ja) 2021-12-09
CN107922501A (zh) 2018-04-17

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