DK307677A - 5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) -OG 5- (3-THENOYL) -1,2-DIHYDRO-3H-PYRROLO (1,2-A ) -PYRROL-1-CARBOXYLIC ACID DERIVATIVES AND MANUFACTURING PROCEDURES - Google Patents

5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) -OG 5- (3-THENOYL) -1,2-DIHYDRO-3H-PYRROLO (1,2-A ) -PYRROL-1-CARBOXYLIC ACID DERIVATIVES AND MANUFACTURING PROCEDURES

Info

Publication number: DK307677A
Authority: DK; Denmark
Prior art keywords: thenoyl; furoyl; pyrrol; pyrrolo; dihydro
Prior art date: 1976-07-14

Application number

DK307677A

Other languages

Danish (da)

Other versions

DK152652B (en

DK152652C (en

Inventor

J M Muchowski

A F Kluge

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-07-14

Filing date

1977-07-07

Publication date

1978-01-15

1977-02-23 Priority claimed from US05/771,283 external-priority patent/US4087539A/en

1977-07-07 Application filed by Syntex Inc filed Critical Syntex Inc

1978-01-15 Publication of DK307677A publication Critical patent/DK307677A/en

1980-11-11 Priority to DK479480A priority Critical patent/DK479480A/en

1980-11-11 Priority to DK479680A priority patent/DK152655C/en

1980-11-11 Priority to DK479380A priority patent/DK152653C/en

1980-11-11 Priority to DK479580A priority patent/DK152654C/en

1988-04-05 Publication of DK152652B publication Critical patent/DK152652B/en

1988-09-12 Application granted granted Critical

1988-09-12 Publication of DK152652C publication Critical patent/DK152652C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

DK307677A 1976-07-14 1977-07-07 ANALOGY PROCEDURE FOR PREPARING 5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) - AND 5- (3-THEONYL) -1,2-DIHYDRO-3H-PYRROLOOE1,2 -AAAPYRROL-1-carboxylic acid esters DK152652C (en)

Priority Applications (4)

Application Number	Priority Date	Filing Date	Title
DK479480A DK479480A (en)	1976-07-14	1980-11-11	(DL) 5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) -OG 5- (3-THENOYL) -1,2-DIHYDRO-3H-PYRROL- (1) , 2-A) -PYRROL-1-CARBOXYLIC ACID ESTERS AND SALTS
DK479680A DK152655C (en)	1976-07-14	1980-11-11	METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) - OR (L) -5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) - OR 5- (3-THENOYL) -1, 2-dihydro-3H-PYRROLOOE1,2-AAAPYRROL-1-carboxylic acid derivatives
DK479380A DK152653C (en)	1976-07-14	1980-11-11	METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) OR (L) -5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) - OR 5- (3-THENOYL) -1, 2-DIHYDRO-3H-PYRROLOOE1,2-AAAPYRROL-1-CARBOXYLIC ACID ESTERS OR SALTS
DK479580A DK152654C (en)	1976-07-14	1980-11-11	METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) - OR (L) -5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (FUROYL) - OR 5- (3-THENOYL) -1,2- dihydro-3H-pyrrol-OE1,2-AAA-pyrrole-1-carboxylic acid

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US70485776A	1976-07-14	1976-07-14
US70485776		1976-07-14
US05/771,283 US4087539A (en)	1976-07-14	1977-02-23	5-(2-Furoyl)-, 5-(2-thenoyl)-, 5-(3-furoyl)- and 5-(3-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
US77128377		1977-02-23

Publications (3)

Publication Number	Publication Date
DK307677A true DK307677A (en)	1978-01-15
DK152652B DK152652B (en)	1988-04-05
DK152652C DK152652C (en)	1988-09-12

Family

ID=27107392

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK307677A DK152652C (en)	1976-07-14	1977-07-07	ANALOGY PROCEDURE FOR PREPARING 5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) - AND 5- (3-THEONYL) -1,2-DIHYDRO-3H-PYRROLOOE1,2 -AAAPYRROL-1-carboxylic acid esters

Country Status (26)

Country	Link
JP (1)	JPS539789A (en)
AR (1)	AR218631A1 (en)
AU (1)	AU513385B2 (en)
CA (1)	CA1100140A (en)
CH (2)	CH644861A5 (en)
CS (1)	CS208724B2 (en)
DE (1)	DE2731662A1 (en)
DK (1)	DK152652C (en)
ES (2)	ES460705A1 (en)
FI (1)	FI63407C (en)
FR (1)	FR2361396A1 (en)
GB (1)	GB1554076A (en)
GR (1)	GR61607B (en)
HK (1)	HK17581A (en)
IE (1)	IE45302B1 (en)
IL (1)	IL52492A (en)
IT (1)	IT1117314B (en)
MY (1)	MY8100371A (en)
NL (1)	NL7707652A (en)
NO (1)	NO147563C (en)
NZ (1)	NZ184611A (en)
PL (1)	PL111408B1 (en)
PT (1)	PT66779B (en)
SE (1)	SE434644B (en)
SU (2)	SU664566A3 (en)
YU (2)	YU43156B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4097579A (en) *	1977-03-31	1978-06-27	Syntex (U.S.A.) Inc.	5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo 1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4140698A (en) *	1977-07-25	1979-02-20	Syntex (Usa) Inc.	1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
US4353829A (en) *	1980-11-21	1982-10-12	Syntex (U.S.A.) Inc.	Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
JPS5910589A (en) *	1982-06-10	1984-01-20	メルク　エンド　カムパニー　インコーポレーテツド	Antiinflammatory and analgesic novel 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a) pyrrole derivative
US4511724A (en) *	1982-06-10	1985-04-16	Merck & Co., Inc.	5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
HU198927B (en) *	1987-01-14	1989-12-28	Richter Gedeon Vegyeszet	Process for producing 1-/substituted aminomethyl/-octa-hydroindolo-(2,3-a)quinolizine derivatives, pharmaceutically applicable acid addition salts thereof, as well as pharmaceutical compositions comprising same
US4874871A (en) *	1987-03-25	1989-10-17	Syntex (U.S.A.) Inc.	Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds

1977
- 1977-05-17 JP JP5697877A patent/JPS539789A/en active Granted
- 1977-07-07 AR AR268357A patent/AR218631A1/en active
- 1977-07-07 GR GR53906A patent/GR61607B/en unknown
- 1977-07-07 DK DK307677A patent/DK152652C/en not_active IP Right Cessation
- 1977-07-08 PT PT66779A patent/PT66779B/en unknown
- 1977-07-08 NL NL7707652A patent/NL7707652A/en not_active Application Discontinuation
- 1977-07-08 IE IE1422/77A patent/IE45302B1/en unknown
- 1977-07-08 CH CH848877A patent/CH644861A5/en not_active IP Right Cessation
- 1977-07-08 CH CH4005/84A patent/CH651045A5/en not_active IP Right Cessation
- 1977-07-08 IL IL52492A patent/IL52492A/en unknown
- 1977-07-11 FI FI772154A patent/FI63407C/en not_active IP Right Cessation
- 1977-07-11 GB GB28923/77A patent/GB1554076A/en not_active Expired
- 1977-07-11 NZ NZ184611A patent/NZ184611A/en unknown
- 1977-07-12 FR FR7721559A patent/FR2361396A1/en active Granted
- 1977-07-12 CS CS774647A patent/CS208724B2/en unknown
- 1977-07-12 CA CA282,600A patent/CA1100140A/en not_active Expired
- 1977-07-13 DE DE19772731662 patent/DE2731662A1/en active Granted
- 1977-07-13 SU SU772504151A patent/SU664566A3/en active
- 1977-07-13 SE SE7708142A patent/SE434644B/en not_active IP Right Cessation
- 1977-07-13 ES ES460705A patent/ES460705A1/en not_active Expired
- 1977-07-13 AU AU26976/77A patent/AU513385B2/en not_active Expired
- 1977-07-13 IT IT68631/77A patent/IT1117314B/en active
- 1977-07-13 PL PL1977199602A patent/PL111408B1/en unknown
- 1977-07-13 NO NO772493A patent/NO147563C/en unknown
- 1977-12-29 SU SU772558960A patent/SU793400A3/en active
1978
- 1978-05-24 ES ES470213A patent/ES470213A1/en not_active Expired
1981
- 1981-04-30 HK HK175/81A patent/HK17581A/en unknown
- 1981-12-30 MY MY371/81A patent/MY8100371A/en unknown
1983
- 1983-02-28 YU YU475/83A patent/YU43156B/en unknown
- 1983-02-28 YU YU476/83A patent/YU43157B/en unknown

Also Published As

Publication number	Publication date
NO147563B (en)	1983-01-24
MY8100371A (en)	1981-12-31
YU43157B (en)	1989-04-30
SE434644B (en)	1984-08-06
ES460705A1 (en)	1979-10-01
JPS539789A (en)	1978-01-28
IL52492A0 (en)	1977-10-31
SU793400A3 (en)	1980-12-30
AU513385B2 (en)	1980-11-27
IL52492A (en)	1981-06-29
FI772154A (en)	1978-01-15
PT66779A (en)	1977-08-01
NL7707652A (en)	1978-01-17
PT66779B (en)	1978-12-18
CA1100140A (en)	1981-04-28
AR218631A1 (en)	1980-06-30
DE2731662A1 (en)	1978-01-19
IT1117314B (en)	1986-02-17
FI63407B (en)	1983-02-28
PL199602A1 (en)	1979-01-29
DE2731662C2 (en)	1989-11-09
HK17581A (en)	1981-05-08
CS208724B2 (en)	1981-09-15
CH644861A5 (en)	1984-08-31
DK152652B (en)	1988-04-05
NZ184611A (en)	1979-03-28
CH651045A5 (en)	1985-08-30
GB1554076A (en)	1979-10-17
AU2697677A (en)	1979-01-18
YU47683A (en)	1984-04-30
DK152652C (en)	1988-09-12
FI63407C (en)	1983-06-10
PL111408B1 (en)	1980-08-30
ES470213A1 (en)	1979-09-16
JPS6254110B2 (en)	1987-11-13
YU47583A (en)	1984-06-30
NO772493L (en)	1978-01-17
SU664566A3 (en)	1979-05-25
GR61607B (en)	1978-12-02
YU43156B (en)	1989-04-30
NO147563C (en)	1983-05-18
SE7708142L (en)	1978-01-15
FR2361396B1 (en)	1981-11-27
IE45302L (en)	1978-01-14
IE45302B1 (en)	1982-07-28
FR2361396A1 (en)	1978-03-10

Publication	Publication Date	Title
ZA774239B (en)	1979-02-28	5-(2-furoyl)-,5-(2-thenoyl)-,5-(3-furoyl)-and 5-(3-thenoyl)-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carboxylic acid derivatives and process for the production thereof
DE3785936D1 (en)	1993-06-24	MACROLIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE.
SE7803549L (en)	1978-10-01	5- (2-PYRROYL) -1,2-DIHYDRO-3H-PYRROLO (1,2-A) -PYRROL-1-CARBONIC ACID DERIVATIVES AND METHODS OF PREPARING THE SAME
DE3870423D1 (en)	1992-05-27	HYBRID, OPTICAL AND ELECTRONIC ASSOCIATIVE MEMORY.
DE3879024D1 (en)	1993-04-15	PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE.
SE7702503L (en)	1977-09-11	PROCEDURE FOR MAKING NEW 2,3-DIHYDROIMIDAZO (2,1-B) THIAZOLE DERIVATIVES
DE68920219D1 (en)	1995-02-09	Temperature compensated bipolar circuits.
ATE73762T1 (en)	1992-04-15	N-AMINOBUTYL-N-PHENYLARYLAMIDE DERIVATIVES, THEIR PRODUCTION AND MEDICAL USE.
DK307677A (en)	1978-01-15	5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) -OG 5- (3-THENOYL) -1,2-DIHYDRO-3H-PYRROLO (1,2-A ) -PYRROL-1-CARBOXYLIC ACID DERIVATIVES AND MANUFACTURING PROCEDURES
DE3784602D1 (en)	1993-04-15	INONOS DERIVATIVES, THEIR PRODUCTION AND USE.
NO772494L (en)	1978-01-17	5-AROYL-1,2-DIHYDRO-3H-PYRROLO (1,2-A) PYRROL-1-CARBOXYLIC ACID DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION
DE3787838D1 (en)	1993-11-25	Circuits with several controlled amplifier elements.
DE3770020D1 (en)	1991-06-20	SULFOXIDE DERIVATIVES AND THEIR PRODUCTION.
DE3865073D1 (en)	1991-10-31	IMIDAZOPYRIDINE DERIVATIVES, THEIR PRODUCTION AND THERAPEUTIC USE.
NO773576L (en)	1978-04-24	TOUR DOCK LOFT PLATFORM.
IT7830109A0 (en)	1978-11-23	INDEL DERIVATIVES.
ATE8256T1 (en)	1984-07-15	PHENYLIMINOMETHYL-3-PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE.
DK479480A (en)	1980-11-11	(DL) 5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) -OG 5- (3-THENOYL) -1,2-DIHYDRO-3H-PYRROL- (1) , 2-A) -PYRROL-1-CARBOXYLIC ACID ESTERS AND SALTS
ATE40367T1 (en)	1989-02-15	4,5,6,7-TETRAHYDROFURO- OR 1H-PYRROLO(2,3C>PYRIDINE DERIVATIVES, THEIR PRODUCTION AND THERAPEUTIC USE.
NO894386L (en)	1990-05-10	ORIGINAL CELL LINE FOR MANUFACTURING HUMAN HYBRIDOMS.
DE3882562D1 (en)	1993-09-02	BENZOYL URINE DERIVATIVES, THEIR PRODUCTION AND USE.
FI896023A0 (en)	1989-12-15	FOERFARANDE FOER SEPARERING AV FURFURAL UR UTSPAEDDA VATTENLOESNINGAR.
NO147244C (en)	1984-10-09	PROCEDURE FOR PREPARING 6,7-DIMETOXY-4-AMINO-2- (4- (2-FUROYL) -1-PIPERAZINYL) CHINAZOLINE
DE3875807D1 (en)	1992-12-17	3-ACYLAMINOMETHYL-5,6,7,8-TETRAHYDROIMIDAZO (1,2-A) PYRIDINE DERIVATIVES, THEIR PRODUCTION AND THERAPEUTIC USE.
NL7602340A (en)	1976-09-14	BENZIMIDAZO (1,2-A) QUINOLINS AND THEIR PREPARATION.

Legal Events

Date	Code	Title	Description
1991-03-25	PBP	Patent lapsed