DK2689251T3 - Fremgangsmåde til detektering og kvantificering af et målmolekyle i en prøve - Google Patents
Fremgangsmåde til detektering og kvantificering af et målmolekyle i en prøve Download PDFInfo
- Publication number
- DK2689251T3 DK2689251T3 DK12709114.8T DK12709114T DK2689251T3 DK 2689251 T3 DK2689251 T3 DK 2689251T3 DK 12709114 T DK12709114 T DK 12709114T DK 2689251 T3 DK2689251 T3 DK 2689251T3
- Authority
- DK
- Denmark
- Prior art keywords
- quantifying
- sample
- detecting
- target molecule
- molecule
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
- H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
- H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0004—Imaging particle spectrometry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Optics & Photonics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Plasma & Fusion (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1152334A FR2973112B1 (fr) | 2011-03-21 | 2011-03-21 | Procede de detection et de quantification d'une molecule cible dans un echantillon |
US201161539681P | 2011-09-27 | 2011-09-27 | |
PCT/EP2012/054768 WO2012126873A1 (en) | 2011-03-21 | 2012-03-19 | Method for detecting and quantifying a target molecule in a sample |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2689251T3 true DK2689251T3 (da) | 2019-09-23 |
Family
ID=44119805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12709114.8T DK2689251T3 (da) | 2011-03-21 | 2012-03-19 | Fremgangsmåde til detektering og kvantificering af et målmolekyle i en prøve |
Country Status (11)
Country | Link |
---|---|
US (2) | US9182409B2 (da) |
EP (1) | EP2689251B1 (da) |
JP (1) | JP6145085B2 (da) |
KR (1) | KR102003825B1 (da) |
CN (2) | CN107179349A (da) |
AU (1) | AU2012230422B2 (da) |
CA (1) | CA2830291C (da) |
DK (1) | DK2689251T3 (da) |
ES (1) | ES2745648T3 (da) |
FR (1) | FR2973112B1 (da) |
WO (1) | WO2012126873A1 (da) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2976076B1 (fr) | 2011-05-31 | 2015-02-27 | Imabiotech | Procede de detection et de quantification d'une molecule cible dans un tissu |
CA2899994C (en) * | 2013-02-25 | 2022-08-30 | Imabiotech | Method to evaluate the tissue targeting of a molecule of interest |
FR3016461B1 (fr) | 2014-01-10 | 2017-06-23 | Imabiotech | Procede de traitement de donnees d'imagerie moleculaire et serveur de donnees correspondant |
CN103901093B (zh) * | 2014-03-13 | 2017-01-04 | 华东理工大学 | 制备亲疏水相间的微阵列芯片及其用于质谱成像定量分析的方法 |
CN104198572A (zh) * | 2014-08-26 | 2014-12-10 | 宜昌捷诺威医药科技有限公司 | 用于检测脂类组合物c18:2ce和sm22:0含量的方法 |
CN105572212B (zh) * | 2014-10-14 | 2018-12-07 | 中国科学院大连化学物理研究所 | 一种基于可视化质谱信息的生晒参和红参快速识别方法 |
CN105574474B (zh) * | 2014-10-14 | 2019-03-12 | 中国科学院大连化学物理研究所 | 一种基于质谱信息的生物特征图像识别方法 |
WO2016090471A1 (en) | 2014-12-08 | 2016-06-16 | University Health Network | System and method for enhanced mass spectrometry imaging |
CA2965435C (en) * | 2014-12-17 | 2022-05-17 | Ventana Medical Systems, Inc. | Accurately calculating acoustic time-of-flight |
EP3254301B1 (en) * | 2015-02-06 | 2021-03-31 | DH Technologies Development Pte. Ltd. | Lipid screening platform allowing a complete solution for lipidomics research |
CN107532212A (zh) * | 2015-02-25 | 2018-01-02 | 新加坡科技研究局 | 用于检测靶分子的装置和方法 |
CN107646089B (zh) * | 2015-03-06 | 2020-12-08 | 英国质谱公司 | 光谱分析 |
KR101746535B1 (ko) | 2015-07-27 | 2017-06-13 | 서강대학교산학협력단 | Maldi-tof 질량분석방법을 이용한 고분자내 올리고머의 정량분석 방법 |
WO2017049403A1 (en) * | 2015-09-22 | 2017-03-30 | University Health Network | System and method for optimized mass spectrometry analysis |
JP6906515B2 (ja) * | 2015-11-20 | 2021-07-21 | トリート4ライフ アーベー | 組織試料での薬物結合分析法 |
US10811242B2 (en) | 2016-06-10 | 2020-10-20 | University Health Network | Soft ionization system and method of use thereof |
KR102535976B1 (ko) * | 2016-06-13 | 2023-05-23 | 건국대학교 산학협력단 | 형광이미지 및 질량 분석을 이용한 의약품의 생체분포도를 상호보완적으로 확인하는 방법 |
EP3610242B1 (en) | 2017-04-13 | 2023-09-27 | F. Hoffmann-La Roche AG | Target molecule density determination in a fluorescence image |
EP3639008B1 (en) * | 2017-06-12 | 2023-03-01 | Protein Dynamic Solutions, Inc. | Method and system for analysis of crystals and crystallization |
SE1750924A1 (sv) * | 2017-07-14 | 2018-10-02 | A method for analyzing the 3d structure of biomolecules | |
CA3125695A1 (en) * | 2019-01-22 | 2020-07-30 | Imabiotech | Method for evaluating molecular changes related to a molecule effect in a biological sample |
CN113518920B (zh) * | 2019-04-24 | 2024-11-05 | 株式会社岛津制作所 | 成像分析装置 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPR892101A0 (en) * | 2001-11-16 | 2001-12-13 | Proteome Systems Ltd | High resolution automated maldi data analysis |
CN101782581A (zh) * | 2002-10-03 | 2010-07-21 | 诺曼·利·安德森 | 用质谱法高灵敏度定量肽 |
JP4547173B2 (ja) * | 2004-03-17 | 2010-09-22 | シスメックス株式会社 | 糖尿病診療支援システム |
EP1953542B9 (en) * | 2005-11-08 | 2013-11-13 | Tohoku University | Method of quantifying membrane protein by using mass spectrometer |
JP5363345B2 (ja) * | 2007-02-21 | 2013-12-11 | ボルボ ラストバグナー アーベー | 排気後処理システムを制御するための制御方法と排気後処理システム |
US8119982B2 (en) * | 2007-04-04 | 2012-02-21 | Shimadzu Corporation | Method and system for mass spectrometry data analysis |
JP2009009684A (ja) * | 2007-06-01 | 2009-01-15 | Fujifilm Corp | 光情報記録媒体および情報記録方法 |
EP2391886A4 (en) * | 2009-04-10 | 2013-04-17 | Canon Kk | METHOD FOR FORMING MASS IMAGE |
JP5478998B2 (ja) * | 2009-09-02 | 2014-04-23 | 公益財団法人野口研究所 | 分析方法 |
WO2011073740A1 (en) * | 2009-12-15 | 2011-06-23 | Centre National De La Recherche Scientifique (Cnrs) | Matrices for mass spectrometry imaging |
-
2011
- 2011-03-21 FR FR1152334A patent/FR2973112B1/fr active Active
-
2012
- 2012-03-19 CN CN201710181856.7A patent/CN107179349A/zh active Pending
- 2012-03-19 AU AU2012230422A patent/AU2012230422B2/en active Active
- 2012-03-19 CN CN201280014694.3A patent/CN103620413B/zh active Active
- 2012-03-19 DK DK12709114.8T patent/DK2689251T3/da active
- 2012-03-19 ES ES12709114T patent/ES2745648T3/es active Active
- 2012-03-19 JP JP2014500343A patent/JP6145085B2/ja active Active
- 2012-03-19 KR KR1020137027714A patent/KR102003825B1/ko active IP Right Grant
- 2012-03-19 CA CA2830291A patent/CA2830291C/en active Active
- 2012-03-19 EP EP12709114.8A patent/EP2689251B1/en active Active
- 2012-03-19 WO PCT/EP2012/054768 patent/WO2012126873A1/en active Application Filing
- 2012-03-21 US US13/425,570 patent/US9182409B2/en active Active
-
2015
- 2015-10-28 US US14/924,823 patent/US20160049284A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20160049284A1 (en) | 2016-02-18 |
CA2830291A1 (en) | 2012-09-27 |
CA2830291C (en) | 2020-06-30 |
AU2012230422A1 (en) | 2013-10-10 |
EP2689251A1 (en) | 2014-01-29 |
FR2973112A1 (fr) | 2012-09-28 |
AU2012230422B2 (en) | 2016-11-10 |
CN103620413A (zh) | 2014-03-05 |
WO2012126873A1 (en) | 2012-09-27 |
KR20140037065A (ko) | 2014-03-26 |
US20120258485A1 (en) | 2012-10-11 |
US9182409B2 (en) | 2015-11-10 |
ES2745648T3 (es) | 2020-03-03 |
CN103620413B (zh) | 2017-12-01 |
KR102003825B1 (ko) | 2019-07-25 |
JP6145085B2 (ja) | 2017-06-07 |
JP2014508946A (ja) | 2014-04-10 |
EP2689251B1 (en) | 2019-06-19 |
FR2973112B1 (fr) | 2018-05-25 |
CN107179349A (zh) | 2017-09-19 |
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