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DK2376121T4 - Slidgigtbehandling - Google Patents

Slidgigtbehandling Download PDF

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Publication number
DK2376121T4
DK2376121T4 DK09833924.5T DK09833924T DK2376121T4 DK 2376121 T4 DK2376121 T4 DK 2376121T4 DK 09833924 T DK09833924 T DK 09833924T DK 2376121 T4 DK2376121 T4 DK 2376121T4
Authority
DK
Denmark
Prior art keywords
osteoarthritis treatment
osteoarthritis
treatment
Prior art date
Application number
DK09833924.5T
Other languages
English (en)
Other versions
DK2376121T3 (da
Inventor
John Allan Hamilton
Andrew David Cook
Original Assignee
Univ Melbourne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42286786&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2376121(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Melbourne filed Critical Univ Melbourne
Publication of DK2376121T3 publication Critical patent/DK2376121T3/da
Application granted granted Critical
Publication of DK2376121T4 publication Critical patent/DK2376121T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Polarising Elements (AREA)
  • Glass Compositions (AREA)
DK09833924.5T 2008-12-22 2009-12-21 Slidgigtbehandling DK2376121T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13967908P 2008-12-22 2008-12-22
US16448609P 2009-03-30 2009-03-30
PCT/AU2009/001672 WO2010071924A1 (en) 2008-12-22 2009-12-21 Osteoarthritis treatment

Publications (2)

Publication Number Publication Date
DK2376121T3 DK2376121T3 (da) 2016-05-30
DK2376121T4 true DK2376121T4 (da) 2021-08-16

Family

ID=42286786

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09833924.5T DK2376121T4 (da) 2008-12-22 2009-12-21 Slidgigtbehandling

Country Status (19)

Country Link
US (4) US9243061B2 (da)
EP (2) EP2376121B2 (da)
JP (3) JP5727379B2 (da)
KR (2) KR101898982B1 (da)
CN (2) CN106397591A (da)
AU (1) AU2009329814B2 (da)
BR (1) BRPI0918356B1 (da)
CA (1) CA2746827C (da)
CY (1) CY1117698T1 (da)
DK (1) DK2376121T4 (da)
ES (2) ES2886063T3 (da)
HK (1) HK1226938A1 (da)
HR (1) HRP20160577T4 (da)
HU (1) HUE028615T2 (da)
PL (1) PL2376121T5 (da)
RU (2) RU2712273C2 (da)
SI (2) SI2376121T2 (da)
SM (1) SMT201600156B (da)
WO (1) WO2010071924A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5674677B2 (ja) 2008-12-22 2015-02-25 ザ ユニバーシティー オブ メルボルンＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ ｏｆ Ｍｅｌｂｏｕｒｎｅ 疼痛治療
HUE028615T2 (en) 2008-12-22 2016-12-28 Univ Melbourne Treatment of osteoarthritis
SG11201501595YA (en) 2012-09-20 2015-05-28 Morphosys Ag Treatment for rheumatoid arthritis
DE102013222200A1 (de) * 2013-10-31 2015-08-27 Osram Opto Semiconductors Gmbh Elektronisches Bauelement und Verfahren zum Herstellen eines elektronischen Bauelements
IL301622A (en) 2017-08-14 2023-05-01 Zynerba Pharmaceuticals Inc Methods of treatment of osteoarthritis with transdermal cannabidiol gel
WO2020104833A1 (en) * 2018-11-19 2020-05-28 4P-Pharma Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production
CN110075304B (zh) * 2019-05-29 2020-02-11 四川大学华西医院 一种治疗骨关节炎的药物组合物及其用途

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* Cited by examiner, † Cited by third party
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US5225539A (en) * 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
KR920701246A (ko) 1989-07-14 1992-08-11 스타이나 브이. 칸스타드 카르복실 말단으로부터 유도된 gm-csf의 길항제
ATE161883T1 (de) 1989-08-11 1998-01-15 Amrad Corp Ltd Rezeptor für granulozyten-macrophagen- koloniestimulierungsfaktor und seine derivate
WO1994009149A1 (en) 1990-08-10 1994-04-28 Amrad Corporation Limited Monoclonal antibody
EP0673389A1 (en) 1992-11-19 1995-09-27 Dana Farber Cancer Institute Antibodies for gm-csf receptor and uses thereof
WO1997008320A1 (en) 1995-08-18 1997-03-06 Morphosys Gesellschaft Für Proteinoptimierung Mbh Protein/(poly)peptide libraries
AUPP525198A0 (en) 1998-08-13 1998-09-03 Medvet Science Pty. Ltd. Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof
US7108852B2 (en) 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
US7455836B2 (en) * 2000-05-08 2008-11-25 The University Of Melbourne Method of treatment and agents useful for same
WO2003035048A2 (en) * 2001-10-26 2003-05-01 Novartis Ag Methods for the treatment of osteoarthritis and compositions thereof
JP2006500905A (ja) 2002-02-13 2006-01-12 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ ヒト化ｇｍ−ｃｓｆ抗体
US20040241755A1 (en) * 2003-06-02 2004-12-02 Pfizer Inc. Human cell assay to determine effect of sample compounds on Col2 enhancer expression
DE602005020743D1 (de) 2004-02-11 2010-06-02 Warner Lambert Co Verfahren zur behandlung von osteoarthritis mit anti-il-6 antikörpern
ES2465141T3 (es) * 2004-03-31 2014-06-05 Kazuwa Nakao Remedio o medicamento preventivo para la artritis
DE602004021773D1 (de) 2004-05-05 2009-08-13 Micromet Ag Herstellung eines einkettigen fv Antikörperfragments
JP2008510168A (ja) * 2004-08-18 2008-04-03 アメリカ合衆国 骨関節炎のバイオマーカー
US20060040258A1 (en) 2004-08-23 2006-02-23 Huiyan Guo Water-soluble conjugates and methods of preparation
RU2458071C2 (ru) 2005-04-18 2012-08-10 Микромет Аг Антитела-нейтрализаторы гранулоцитарно-макрофагального колониестимулирующего фактора человека
PL1888643T3 (pl) 2005-05-18 2015-04-30 Morphosys Ag Przeciwciała przeciwko GM-CSF i ich zastosowania
JP4736037B2 (ja) 2005-10-26 2011-07-27 株式会社イーベック ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分
US20080311111A1 (en) * 2005-12-01 2008-12-18 Drew Philip D Competitive Domain Antibody Formats That Bind Interleukin 1 Receptor Type 1
WO2007092939A2 (en) * 2006-02-08 2007-08-16 Morphotek, Inc. Antigenic gm-csf peptides and antibodies to gm-csf
PT2423229E (pt) * 2006-03-27 2013-08-22 Medimmune Ltd Membro de ligação para o recetor de gm-csf
US7741273B2 (en) 2006-04-13 2010-06-22 Warsaw Orthopedic, Inc. Drug depot implant designs
BRPI0719109A2 (pt) 2006-11-21 2013-12-10 Kalobios Pharmaceuticals Inc Métodos para tratar doenças inflamatórias crônicas usando um antagonista de gm-csf
WO2008080134A2 (en) * 2006-12-22 2008-07-03 Rigel Pharmaceuticals, Inc. 4-amin0-2- (hetero) arylamino-5- (hetero) arylthiazoles useful as axl inhibitors
AU2008253608A1 (en) * 2007-05-23 2008-11-27 Crc For Asthma And Airways Ltd Neutralizing antibodies
TW200918553A (en) 2007-09-18 2009-05-01 Amgen Inc Human GM-CSF antigen binding proteins
US20090163440A1 (en) * 2007-09-26 2009-06-25 Waddell David D Ion-Channel Regulator Compositions and Methods of Using Same
AU2008323608A1 (en) 2007-11-12 2009-05-22 Crc For Asthma And Airways Ltd Epitope for neutralizing antibodies
SG176499A1 (en) * 2007-11-13 2011-12-29 Evec Inc Monoclonal antibodies that bind to hgm-csf and medical compositions comprising same
WO2009118662A2 (en) 2008-03-24 2009-10-01 Abbott Biotechnology Ltd. Methods and compositions for treating bone loss
JP5688363B2 (ja) * 2008-04-28 2015-03-25 カロバイオス ファーマシューティカルズ インコーポレイティッド 顆粒球−マクロファージコロニー刺激因子に対する抗体
HUE028615T2 (en) 2008-12-22 2016-12-28 Univ Melbourne Treatment of osteoarthritis
JP5674677B2 (ja) 2008-12-22 2015-02-25 ザ ユニバーシティー オブ メルボルンＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ ｏｆ Ｍｅｌｂｏｕｒｎｅ 疼痛治療
CN102459340A (zh) 2009-04-23 2012-05-16 特罗科隆科学有限公司 粒性白血细胞-巨噬细胞菌落-刺激因子(gm-csf)中和抗体

Also Published As

Publication number Publication date
JP5727379B2 (ja) 2015-06-03
EP3056217A1 (en) 2016-08-17
RU2011127334A (ru) 2013-01-27
EP2376121A4 (en) 2013-04-03
JP2012512815A (ja) 2012-06-07
AU2009329814A1 (en) 2010-07-01
RU2016102339A (ru) 2018-11-21
KR101799264B1 (ko) 2017-11-20
US20200247895A1 (en) 2020-08-06
CN102271705A (zh) 2011-12-07
EP2376121A1 (en) 2011-10-19
EP2376121B2 (en) 2021-06-09
JP2015143233A (ja) 2015-08-06
ES2572368T5 (es) 2021-12-16
DK2376121T3 (da) 2016-05-30
HUE028615T2 (en) 2016-12-28
SI2376121T1 (sl) 2016-07-29
ES2572368T3 (es) 2016-05-31
EP3056217B1 (en) 2021-06-30
US20120003234A1 (en) 2012-01-05
RU2016102339A3 (da) 2019-07-29
US20180066062A1 (en) 2018-03-08
KR101898982B1 (ko) 2018-09-14
CY1117698T1 (el) 2017-05-17
JP2017200933A (ja) 2017-11-09
HK1226938A1 (zh) 2017-10-13
US20160185868A1 (en) 2016-06-30
KR20110128273A (ko) 2011-11-29
CN106397591A (zh) 2017-02-15
CA2746827C (en) 2018-01-23
SI2376121T2 (sl) 2021-11-30
AU2009329814B2 (en) 2015-06-18
SMT201600156B (it) 2016-08-31
PL2376121T5 (pl) 2021-09-27
JP6458086B2 (ja) 2019-01-23
HRP20160577T1 (hr) 2016-07-29
ES2886063T3 (es) 2021-12-16
WO2010071924A1 (en) 2010-07-01
EP2376121B1 (en) 2016-03-09
KR20170128630A (ko) 2017-11-22
US9243061B2 (en) 2016-01-26
HRP20160577T4 (hr) 2021-08-20
BRPI0918356A2 (pt) 2020-10-06
CA2746827A1 (en) 2010-07-01
PL2376121T3 (pl) 2016-12-30
BRPI0918356B1 (pt) 2022-03-08
RU2712273C2 (ru) 2020-01-28

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