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DK216589A - DNA SEQUENCES, RECOMBINANT DNA MOLECULES, AND PROCEDURES FOR PROMOTING SOLUBLE T4 PROTEINS - Google Patents

DNA SEQUENCES, RECOMBINANT DNA MOLECULES, AND PROCEDURES FOR PROMOTING SOLUBLE T4 PROTEINS Download PDF

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Publication number
DK216589A
DK216589A DK216589A DK216589A DK216589A DK 216589 A DK216589 A DK 216589A DK 216589 A DK216589 A DK 216589A DK 216589 A DK216589 A DK 216589A DK 216589 A DK216589 A DK 216589A
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DK
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Prior art keywords
proteins
procedures
recombinant dna
dna sequences
dna molecules
Prior art date
Application number
DK216589A
Other languages
Danish (da)
Other versions
DK216589D0 (en
Inventor
Richard A Fischer
Walter Gilbert
Vicki L Sato
Richard A Flavell
John M Maraganore
Theresa R Liu
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc filed Critical Biogen Inc
Publication of DK216589D0 publication Critical patent/DK216589D0/en
Publication of DK216589A publication Critical patent/DK216589A/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70514CD4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • G01N33/56988HIV or HTLV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15051Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Transplantation (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
DK216589A 1987-09-04 1989-05-03 DNA SEQUENCES, RECOMBINANT DNA MOLECULES, AND PROCEDURES FOR PROMOTING SOLUBLE T4 PROTEINS DK216589A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9432287A 1987-09-04 1987-09-04
US14164988A 1988-01-07 1988-01-07
PCT/US1988/002940 WO1989001940A1 (en) 1987-09-04 1988-09-01 Dna sequences, recombinant dna molecules and processes for producing soluble t4 proteins

Publications (2)

Publication Number Publication Date
DK216589D0 DK216589D0 (en) 1989-05-03
DK216589A true DK216589A (en) 1989-07-04

Family

ID=26788733

Family Applications (1)

Application Number Title Priority Date Filing Date
DK216589A DK216589A (en) 1987-09-04 1989-05-03 DNA SEQUENCES, RECOMBINANT DNA MOLECULES, AND PROCEDURES FOR PROMOTING SOLUBLE T4 PROTEINS

Country Status (12)

Country Link
EP (1) EP0347435A4 (en)
JP (1) JPH02501192A (en)
KR (1) KR890701605A (en)
DK (1) DK216589A (en)
ES (1) ES2013346A6 (en)
GR (1) GR1000489B (en)
IL (1) IL87647A0 (en)
NO (1) NO891818L (en)
NZ (1) NZ226040A (en)
OA (1) OA09625A (en)
PT (1) PT88425B (en)
WO (1) WO1989001940A1 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958678A (en) * 1986-08-21 1999-09-28 The Trustees Of Columbia University In The City Of New York DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS
DE3751751T2 (en) 1986-08-21 1996-10-17 Univ Columbia DNA ENCODING THE T CELL SURFACE PROTEIN T4 AND USE OF T4 FRAGMENTS IN THE TREATMENT OF AIDS
US5336603A (en) * 1987-10-02 1994-08-09 Genentech, Inc. CD4 adheson variants
US6710169B2 (en) 1987-10-02 2004-03-23 Genentech, Inc. Adheson variants
ZA887365B (en) * 1987-10-02 1990-05-30 Genentech Inc Adheson variants
US6004781A (en) * 1988-01-22 1999-12-21 The General Hospital Corporation Nucleic acid encoding Ig-CD4 fusion proteins
PT89484B (en) * 1988-01-22 1994-03-31 Gen Hospital Corp GENE CLONED CODES OF FUSAO PROTEINS IG-CD4 AND ITS UTILIZATION
AU3006789A (en) * 1988-02-24 1989-08-24 Smithkline Beckman Corporation Expression of hiv binding proteins
EP0346091A3 (en) * 1988-06-10 1990-09-12 Dana Farber Cancer Institute Method of diagnosis for naturally occurring antibodies to cd4
WO1990005534A1 (en) * 1988-11-23 1990-05-31 Genentech, Inc. Polypeptide derivatives
AU5437190A (en) * 1989-04-05 1990-11-05 Upjohn Company, The Soluble cd4 produced in (e. coli)
EP0408372A1 (en) * 1989-07-13 1991-01-16 Smithkline Beecham Corporation Anti-viral therapy
AU648041B2 (en) * 1989-08-23 1994-04-14 General Hospital Corporation, The Non-human primate CD4 polypeptides, fusions thereof, DNA encoding, and uses thereof
US5180820A (en) * 1989-08-30 1993-01-19 Barde Yves Alain Brain-derived neurotrophic factor
JPH0725794B2 (en) * 1990-03-23 1995-03-22 呉羽化学工業株式会社 Novel peptide
AU7976791A (en) * 1990-05-25 1991-12-31 Biogen, Inc. Immunotherapeutic compositions for treating and preventing aids, arc and hiv infection
WO1992009305A1 (en) * 1990-11-27 1992-06-11 Biogen, Inc. Anti cd-4 antibodies blocking hiv-induced syncytia
EP0528011A4 (en) 1991-02-08 1993-06-30 Progenics Pharmaceuticals, Inc. Cd4-gamma2 and cd4-igg2 chimeras
WO1992013559A1 (en) * 1991-02-08 1992-08-20 Progenics Pharmaceuticals, Inc. CD4-GAMMA1 AND CD4-IgG1 CHIMERAS
US7070991B2 (en) 1991-02-08 2006-07-04 Progenics Pharmaceuticals, Inc. Cells expressing a CD4-IgG2 chimeric heterotetramer
US5389529A (en) * 1991-06-12 1995-02-14 Regeneron Pharmaceuticals, Inc. Modified lamβ signal sequence and processes for producing recombinant neurotrophins
GB9219562D0 (en) 1992-03-11 1992-10-28 Prendergast Kennet F Anti-viral peptides
ATE393236T1 (en) * 1994-11-04 2008-05-15 Idexx Lab Inc MEDIUM FOR DETECTING CERTAIN MICROBEES IN A SAMPLE
US5635363A (en) * 1995-02-28 1997-06-03 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for the detection, quantitation and purification of antigen-specific T cells
CA2223088A1 (en) 1995-06-07 1996-12-19 Bob Dale Brown Novel carbamate-based cationic lipids
ES2299276T3 (en) 1998-12-31 2008-05-16 Novartis Vaccines And Diagnostics, Inc. MODIFIED HIV ENV POLIPEPTIDES.
EP1980617A1 (en) 1998-12-31 2008-10-15 Novartis Vaccines and Diagnostics, Inc. Improved expression of HIV polypeptides and production of virus-like particles
EP1141314A2 (en) 1998-12-31 2001-10-10 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
US7935805B1 (en) 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
US20030194800A1 (en) 2001-08-31 2003-10-16 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
EP1411770A4 (en) 2001-07-05 2006-05-10 Chiron Corp Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
CN113209124B (en) * 2021-02-24 2022-04-15 四川大学 Application of DNA tetrahedron in preparation of medicines for preventing and treating type 1 diabetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3751751T2 (en) * 1986-08-21 1996-10-17 Univ Columbia DNA ENCODING THE T CELL SURFACE PROTEIN T4 AND USE OF T4 FRAGMENTS IN THE TREATMENT OF AIDS
IL83687A (en) * 1987-08-30 1995-03-30 Yeda Res & Dev Pharmaceutical compositions comprising molecular decays and their use in the manufacture of said compositions
PT88641B (en) * 1987-10-02 1993-04-30 Genentech Inc METHOD FOR PREPARING A VARIETY OF ADHESION

Also Published As

Publication number Publication date
NO891818L (en) 1989-07-03
AU626007B2 (en) 1992-07-23
EP0347435A4 (en) 1991-11-21
NZ226040A (en) 1992-02-25
KR890701605A (en) 1989-12-21
WO1989001940A1 (en) 1989-03-09
AU2482988A (en) 1989-03-31
JPH02501192A (en) 1990-04-26
GR880100579A (en) 1989-06-22
NO891818D0 (en) 1989-05-02
EP0347435A1 (en) 1989-12-27
DK216589D0 (en) 1989-05-03
GR1000489B (en) 1992-07-30
ES2013346A6 (en) 1990-05-01
PT88425B (en) 1992-10-30
IL87647A0 (en) 1989-02-28
PT88425A (en) 1989-07-31
OA09625A (en) 1993-04-30

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