DK2012816T3 - Use of Thymosin 1, alone or in combination with PTX3 or Ganciclovir, for the treatment of Cytomegalovirus infection. - Google Patents

Use of Thymosin 1, alone or in combination with PTX3 or Ganciclovir, for the treatment of Cytomegalovirus infection.

Info

Publication number: DK2012816T3
Authority: DK; Denmark
Prior art keywords: ptx3; thymosin; ganciclovir; alone; treatment
Prior art date: 2006-05-02

Application number

DK07728041.0T

Other languages

Danish (da)

Inventor

Luigina Romani

Francesco Bistoni

Enrico Garaci

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-05-02

Filing date

2007-04-12

Publication date

2012-09-03

2007-04-12 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

2012-09-03 Application granted granted Critical

2012-09-03 Publication of DK2012816T3 publication Critical patent/DK2012816T3/en

Links

206010011831 Cytomegalovirus infection Diseases 0.000 title 1
101001082142 Homo sapiens Pentraxin-related protein PTX3 Proteins 0.000 title 1
BFHAYPLBUQVNNJ-UHFFFAOYSA-N Pectenotoxin 3 Natural products OC1C(C)CCOC1(O)C1OC2C=CC(C)=CC(C)CC(C)(O3)CCC3C(O3)(O4)CCC3(C=O)CC4C(O3)C(=O)CC3(C)C(O)C(O3)CCC3(O3)CCCC3C(C)C(=O)OC2C1 BFHAYPLBUQVNNJ-UHFFFAOYSA-N 0.000 title 1
102100027351 Pentraxin-related protein PTX3 Human genes 0.000 title 1
102000007501 Thymosin Human genes 0.000 title 1
108010046075 Thymosin Proteins 0.000 title 1
IRSCQMHQWWYFCW-UHFFFAOYSA-N ganciclovir Chemical compound O=C1NC(N)=NC2=C1N=CN2COC(CO)CO IRSCQMHQWWYFCW-UHFFFAOYSA-N 0.000 title 1
229960002963 ganciclovir Drugs 0.000 title 1
LCJVIYPJPCBWKS-NXPQJCNCSA-N thymosin Chemical compound SC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(O)=O LCJVIYPJPCBWKS-NXPQJCNCSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Virology (AREA)
Endocrinology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Marine Sciences & Fisheries (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK07728041.0T 2006-05-02 2007-04-12 Use of Thymosin 1, alone or in combination with PTX3 or Ganciclovir, for the treatment of Cytomegalovirus infection. DK2012816T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP06113401		2006-05-02
PCT/EP2007/053574 WO2007128647A1 (en)	2006-05-02	2007-04-12	USE OF THYMOSIN α1, ALONE OR IN COMBINATION WITH PTX3 OR GANCICLOVIR, FOR THE TREATMENT OF CYTOMEGALOVIRUS INFECTION

Publications (1)

Publication Number	Publication Date
DK2012816T3 true DK2012816T3 (en)	2012-09-03

Family

ID=36658736

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK07728041.0T DK2012816T3 (en)	2006-05-02	2007-04-12	Use of Thymosin 1, alone or in combination with PTX3 or Ganciclovir, for the treatment of Cytomegalovirus infection.

Country Status (18)

Country	Link
US (1)	US8337828B2 (en)
EP (1)	EP2012816B1 (en)
JP (1)	JP5441685B2 (en)
KR (1)	KR101380360B1 (en)
CN (1)	CN101437535B (en)
AU (1)	AU2007247292B2 (en)
BR (1)	BRPI0711136A2 (en)
CA (1)	CA2649063C (en)
CY (1)	CY1113277T1 (en)
DK (1)	DK2012816T3 (en)
ES (1)	ES2389452T3 (en)
HR (1)	HRP20120676T1 (en)
MX (1)	MX2008013872A (en)
PL (1)	PL2012816T3 (en)
PT (1)	PT2012816E (en)
RS (1)	RS52377B (en)
SI (1)	SI2012816T1 (en)
WO (1)	WO2007128647A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1298487B1 (en) *	1997-12-19	2000-01-10	Sigma Tau Ind Farmaceuti	PHARMACEUTICAL COMPOSITIONS INCLUDING PENTRAXIN LONG PTX3 FOR THE THERAPY OF INFECTIOUS, INFLAMMATORY OR CANCER TYPE DISEASES,
ITRM20040223A1 (en) *	2004-05-07	2004-08-07	Sigma Tau Ind Farmaceuti	MEDICATION FOR THE TREATMENT OF FUNGAL INFECTIONS, IN PARTICULAR ASPERGILLOSIS.
EP1832295A1 (en) *	2006-03-10	2007-09-12	Tecnogen S.P.A.	Use of PTX3 for the treatment of viral diseases
US8829173B2 (en) *	2008-09-26	2014-09-09	Tocagen Inc.	Recombinant vectors
EP2427213B1 (en) *	2009-05-08	2015-04-01	Sciclone Pharmaceuticals, Inc.	Alpha thymosin peptides as vaccine enhancers
US20140213506A1 (en) *	2011-02-09	2014-07-31	Cynthia W. TUTHILL	Thymosin alpha peptide for preventing, reducing the severity of, and treating infection
ES2786051T3 (en)	2012-10-25	2020-10-08	Tocagen Inc	Retroviral vector with mini-promoter cassette

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6106868A (en) *	1990-08-24	2000-08-22	The Board Of Governors Of Wayne State University	Method for the treatment of hepatitis
TW224053B (en) *	1991-09-13	1994-05-21	Paul B Chretien
CN1072961C (en) *	1993-03-05	2001-10-17	施塞克龙药品公司	Method of treating hepatitis C in non-responders to interferon treatment
US6200952B1 (en) *	1993-06-02	2001-03-13	Sciclone Pharmaceuticals, Inc.	Combination therapy method for treating chronic hepatitis B
US5632983A (en) *	1994-11-17	1997-05-27	University Of South Florida	Method for treating secondary immunodeficiency
WO1998018491A1 (en) *	1996-10-28	1998-05-07	BURGSTINER, Jacqueline, Cook	Methods and compositions for dietary supplementation
US5939423A (en) *	1997-04-16	1999-08-17	Sciclone Pharmaceuticals, Inc.	Treatment of hepatitis B infection with thymosin alpha 1 and famciclovir
IT1298487B1 (en) *	1997-12-19	2000-01-10	Sigma Tau Ind Farmaceuti	PHARMACEUTICAL COMPOSITIONS INCLUDING PENTRAXIN LONG PTX3 FOR THE THERAPY OF INFECTIOUS, INFLAMMATORY OR CANCER TYPE DISEASES,
US6288033B1 (en) *	1998-09-25	2001-09-11	Sciclone Pharmaceuticals, Inc.	Treatment of hepatitis B infection with thymosin alpha 1 in combination with lamivudine or in combination with lamivudine and famciclovir
IT1317927B1 (en)	2000-11-03	2003-07-15	Sigma Tau Ind Farmaceuti	USE OF LONG PENTRAXIN PTX3 FOR THE PREPARATION OF A MEDICINE FOR THE TREATMENT OF AUTOIMMUNE PATHOLOGIES.
IT1317930B1 (en)	2000-11-08	2003-07-15	Sigma Tau Ind Farmaceuti	USE OF LONG PENTRAXIN PTX3 FOR THE PREPARATION OF A MEDICATION FOR THE TREATMENT OF PATALOGIES ASSOCIATED WITH AN ALTERED ACTIVATION
BR0211619A (en)	2001-08-03	2004-08-24	Sigma Tau Ind Farmaceuti	Use of long ptx3 pentraxine for treatment of female infertility
US20050020495A1 (en) *	2001-10-24	2005-01-27	Martins Eduardo Bruno Guimaraes	Antiretroviral compositions comprising thymosin alpha peptides and protease inhibitors
AU2004232847B2 (en)	2003-04-23	2008-11-20	Sciclone Pharmaceuticals, Inc.	Treatment or prevention of respiratory viral infections with alpha thymosin peptides
ITRM20030596A1 (en)	2003-12-23	2005-06-24	Sigma Tau Ind Farmaceuti	USE OF INHIBITORS OF LONG PTX3 PENTRAXINE, FOR THE PREPARATION OF A MEDICATION FOR THE PREVENTION AND TREATMENT OF PATHOLOGIES WHICH REPLY TO THE INHIBITION OF THE BIOLOGICAL ACTIVITY OF ITS PTX3.
EP1832295A1 (en) *	2006-03-10	2007-09-12	Tecnogen S.P.A.	Use of PTX3 for the treatment of viral diseases

2007
- 2007-04-12 PT PT07728041T patent/PT2012816E/en unknown
- 2007-04-12 EP EP07728041A patent/EP2012816B1/en active Active
- 2007-04-12 MX MX2008013872A patent/MX2008013872A/en active IP Right Grant
- 2007-04-12 DK DK07728041.0T patent/DK2012816T3/en active
- 2007-04-12 WO PCT/EP2007/053574 patent/WO2007128647A1/en active Application Filing
- 2007-04-12 PL PL07728041T patent/PL2012816T3/en unknown
- 2007-04-12 KR KR1020087029405A patent/KR101380360B1/en not_active Expired - Fee Related
- 2007-04-12 ES ES07728041T patent/ES2389452T3/en active Active
- 2007-04-12 CA CA2649063A patent/CA2649063C/en not_active Expired - Fee Related
- 2007-04-12 JP JP2009508294A patent/JP5441685B2/en not_active Expired - Fee Related
- 2007-04-12 SI SI200730976T patent/SI2012816T1/en unknown
- 2007-04-12 AU AU2007247292A patent/AU2007247292B2/en not_active Ceased
- 2007-04-12 US US12/298,643 patent/US8337828B2/en not_active Expired - Fee Related
- 2007-04-12 CN CN2007800159035A patent/CN101437535B/en not_active Expired - Fee Related
- 2007-04-12 RS RS20120363A patent/RS52377B/en unknown
- 2007-04-12 BR BRPI0711136-3A patent/BRPI0711136A2/en not_active IP Right Cessation
- 2007-04-12 HR HRP20120676TT patent/HRP20120676T1/en unknown
2012
- 2012-08-23 CY CY20121100756T patent/CY1113277T1/en unknown

Also Published As

Publication number	Publication date
CN101437535A (en)	2009-05-20
WO2007128647A1 (en)	2007-11-15
CA2649063A1 (en)	2007-11-15
US8337828B2 (en)	2012-12-25
SI2012816T1 (en)	2012-09-28
ES2389452T3 (en)	2012-10-26
AU2007247292B2 (en)	2012-04-05
KR20090007621A (en)	2009-01-19
PT2012816E (en)	2012-08-17
JP2009535373A (en)	2009-10-01
BRPI0711136A2 (en)	2011-08-30
PL2012816T3 (en)	2012-11-30
US20090275508A1 (en)	2009-11-05
EP2012816A1 (en)	2009-01-14
EP2012816B1 (en)	2012-06-27
HK1128622A1 (en)	2009-11-06
CA2649063C (en)	2014-11-25
AU2007247292A1 (en)	2007-11-15
RS52377B (en)	2012-12-31
CY1113277T1 (en)	2016-04-13
KR101380360B1 (en)	2014-04-09
JP5441685B2 (en)	2014-03-12
MX2008013872A (en)	2008-11-14
CN101437535B (en)	2013-01-30
HRP20120676T1 (en)	2012-09-30

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