DK2006294T3 - MHC-molekyler bindende tumorassocierede peptider - Google Patents

MHC-molekyler bindende tumorassocierede peptider

Info

Publication number: DK2006294T3
Authority: DK; Denmark
Prior art keywords: cancer cells; cells; ile; val; incubated
Prior art date: 2002-05-29

Application number

DK08014304.3T

Other languages

English (en)

Inventor

Toni Weinschenk

Hans-Georg Rammensee

Stefan Stevanovic

Original Assignee

Immatics Biotechnologies Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-29

Filing date

2003-03-27

Publication date

2010-12-13

2003-03-27 Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh

2010-12-13 Application granted granted Critical

2010-12-13 Publication of DK2006294T3 publication Critical patent/DK2006294T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A61K39/4611—
- A61K39/4644—
- A61K39/46445—
- A61K39/464452—
- A61K39/464838—
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56977—HLA or MHC typing
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/828—Cancer

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Cell Biology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
General Physics & Mathematics (AREA)
Biotechnology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Pathology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Tropical Medicine & Parasitology (AREA)
Toxicology (AREA)
Oncology (AREA)
Virology (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
Reproductive Health (AREA)

DK08014304.3T 2002-05-29 2003-03-27 MHC-molekyler bindende tumorassocierede peptider DK2006294T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10225144A DE10225144A1 (de)	2002-05-29	2002-05-29	An MHC-Moleküle bindende Tumor-assoziierte Peptide
EP03720376A EP1507795B1 (de)	2002-05-29	2003-03-27	An mhc-moleküle bindende tumor-assoziierte peptide

Publications (1)

Publication Number	Publication Date
DK2006294T3 true DK2006294T3 (da)	2010-12-13

Family

ID=29557592

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
DK03720376T DK1507795T3 (da)	2002-05-29	2003-03-27	Tumorassocierede peptider, der binder til MHC-molekyler
DK08014304.3T DK2006294T3 (da)	2002-05-29	2003-03-27	MHC-molekyler bindende tumorassocierede peptider
DK06015805T DK1734048T3 (da)	2002-05-29	2003-03-27	Tumorassocierede peptider, der binder til MHC-molekyler
DK06015806T DK1734049T3 (da)	2002-05-29	2003-03-27	Tumorassocierede peptider, der binder til MHC-molekyler
DK08014305.0T DK2014673T3 (da)	2002-05-29	2003-03-27	Til MHC-molekyler bindende tumorassocierede peptider

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK03720376T DK1507795T3 (da)	2002-05-29	2003-03-27	Tumorassocierede peptider, der binder til MHC-molekyler

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
DK06015805T DK1734048T3 (da)	2002-05-29	2003-03-27	Tumorassocierede peptider, der binder til MHC-molekyler
DK06015806T DK1734049T3 (da)	2002-05-29	2003-03-27	Tumorassocierede peptider, der binder til MHC-molekyler
DK08014305.0T DK2014673T3 (da)	2002-05-29	2003-03-27	Til MHC-molekyler bindende tumorassocierede peptider

Country Status (15)

Country	Link
US (5)	US7396904B2 (da)
EP (5)	EP1734048B1 (da)
JP (5)	JP4472520B2 (da)
AT (5)	ATE416188T1 (da)
AU (2)	AU2003224001B2 (da)
CA (5)	CA2736972C (da)
CY (5)	CY1108507T1 (da)
DE (6)	DE10225144A1 (da)
DK (5)	DK1507795T3 (da)
ES (5)	ES2348468T3 (da)
HR (1)	HRP20041108B1 (da)
PL (5)	PL211158B1 (da)
PT (5)	PT1734049E (da)
SI (5)	SI1734048T1 (da)
WO (1)	WO2003102023A1 (da)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7892559B2 (en) *	2002-01-30	2011-02-22	Survac Aps	Survivin-derived peptides and use thereof
DE10225139A1 (de) *	2002-05-29	2004-02-26	Immatics Biotechnologies Gmbh	Verfahren zur Identifizierung von immunreaktiven Peptiden
US20050221350A1 (en)	2002-05-29	2005-10-06	Toni Weinschenk	Method for identifying immunoreactive peptides
US7670604B2 (en)	2002-12-13	2010-03-02	Aurelium Biopharma, Inc.	Vimentin directed diagnostics and therapeutics for multidrug resistant neoplastic disease
CN103288920B (zh) *	2003-01-30	2015-08-12	苏瓦克有限公司	存活蛋白衍生肽及其用途
DE10313819A1 (de) *	2003-03-24	2004-10-07	Immatics Biotechnologies Gmbh	An MHC-Moleküle bindende Tumor-assoziierte Peptide
CN102030817B (zh) *	2003-12-01	2012-11-21	株式会社明治	血管紧张素转化酶抑制肽
JP2007515924A (ja) *	2003-12-15	2007-06-21	アウレリウムバイオファーマインク．	ビメンチン指向性診断法、および、多剤耐性を示す腫瘍性疾患の治療法
DE102004011503A1 (de) *	2004-01-28	2005-09-15	Immatics Biotechnologies Gmbh	Verfahren zur Identifizierung und Quantifizierung von tumor-assoziierten Peptiden
DE102004026135A1 (de)	2004-05-25	2006-01-05	Immatics Biotechnologies Gmbh	An MHC-Moleküle bindende Tumor-assoziierte Peptide
EP1642905B1 (en) *	2004-10-02	2009-01-21	Immatics Biotechnologies GmbH	Immunogenic T-helper epitopes from human tumour antigens and immunotherapeutic methods using said epitopes
IL172896A0 (en) *	2005-12-29	2006-06-11	Yeda Res & Dev	Cxcr4 inhibition
US20090004213A1 (en) *	2007-03-26	2009-01-01	Immatics Biotechnologies Gmbh	Combination therapy using active immunotherapy
EP2183278B1 (en)	2007-07-27	2018-07-04	Immatics Biotechnologies GmbH	Novel immunogenic epitopes for immunotherapy
WO2009129498A2 (en) *	2008-04-17	2009-10-22	Immuneregen Biosciences, Inc.	Substance p and analogs thereof as a cancer immunogenic composition adjuvant
PT2119726E (pt)	2008-05-14	2015-03-30	Immatics Biotechnologies Gmbh	Novos e poderosos peptídeos para mhc classe ii derivados de survinina e neurocano
CN101451975B (zh) *	2008-12-29	2012-01-25	浙江大学	一种检测胃癌预后与分期血清蛋白质的方法
US8075895B2 (en) *	2009-09-22	2011-12-13	Janssen Pharmaceutica N.V.	Identification of antigenic peptides from multiple myeloma cells
GB201004575D0 (en)	2010-03-19	2010-05-05	Immatics Biotechnologies Gmbh	Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers
GB201009222D0 (en) *	2010-06-02	2010-07-21	Immatics Biotechnologies Gmbh	Improved cancer therapy based on tumour associated antigens derived from cyclin D1
WO2012048190A1 (en)	2010-10-08	2012-04-12	Regents Of The University Of Minnesota	Annexin ii compositions and methods
RS62602B1 (sr)	2013-08-05	2021-12-31	Immatics Biotechnologies Gmbh	Nova imunoterapija za lečenje nekoliko tumora, kao što je rak pluća, uključujući nsclc
JPWO2015050259A1 (ja) *	2013-10-03	2017-03-09	大日本住友製薬株式会社	腫瘍抗原ペプチド
WO2015073632A1 (en)	2013-11-13	2015-05-21	Regents Of The University Of Minnesota	Annexin ii variant compositions and methods
GB201505305D0 (en)	2015-03-27	2015-05-13	Immatics Biotechnologies Gmbh	Novel Peptides and combination of peptides for use in immunotherapy against various tumors
FI3388075T3 (fi)	2015-03-27	2023-08-18	Immatics Biotechnologies Gmbh	Uusia peptidejä ja peptidien yhdistelmiä käytettäviksi immunoterapiaan erilaisia syöpiä vastaan
NL2014935B1 (en)	2015-06-08	2017-02-03	Applied Immune Tech Ltd	T cell receptor like antibodies having fine specificity.
GB201511546D0 (en)	2015-07-01	2015-08-12	Immatics Biotechnologies Gmbh	Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
IL308735A (en)	2015-07-01	2024-01-01	Immatics Biotechnologies Gmbh	New peptides and combinations of peptides used in immunotherapy against ovarian cancer and other types of cancer
GB201520568D0 (en)	2015-11-23	2016-01-06	Immunocore Ltd	Peptides
GB201520550D0 (en)	2015-11-23	2016-01-06	Immunocore Ltd & Adaptimmune Ltd	Peptides
GB201520558D0 (en) *	2015-11-23	2016-01-06	Immunocore Ltd & Adaptimmune Ltd	Peptides
GB201521746D0 (en)	2015-12-10	2016-01-27	Immatics Biotechnologies Gmbh	Novel peptides and combination of peptides for use in immunotherapy against CLL and other cancers
SG10202111399YA (en)	2015-12-22	2021-11-29	Immatics Biotechnologies Gmbh	Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers
DE102016005550B4 (de)	2016-05-09	2024-09-26	Hans-Georg Rammensee	Adjuvans zur lnduzierung einer zellulären lmmunantwort
JP7075125B2 (ja)	2016-05-25	2022-05-25	イマティクスバイオテクノロジーズゲーエムベーハー	標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ
GB201609193D0 (en) *	2016-05-25	2016-07-06	Immatics Biotechnologies Gmbh	Novel peptides, combination of peptides as targets for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers
DE102016123893A1 (de)	2016-12-08	2018-06-14	Immatics Biotechnologies Gmbh	T-Zellrezeptoren mit verbesserter Bindung
KR102639592B1 (ko)	2016-12-08	2024-02-21	이매틱스 바이오테크놀로지스 게엠베하	짝짓기가 향상된 t 세포 수용체
KR102184377B1 (ko)	2018-02-19	2020-11-30	고려대학교 산학협력단	열충격단백질의 에피토프를 포함하는 백신 및 이의 용도
WO2019160383A1 (ko) *	2018-02-19	2019-08-22	고려대학교 산학협력단	열충격단백질의 에피토프를 포함하는 백신 및 이의 용도
BR102018010523A2 (pt) *	2018-05-23	2020-04-28	Univ Estadual Campinas Unicamp	peptídeo, composição farmacêutica compreendendo o mesmo e uso

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4810781A (en) *	1987-01-15	1989-03-07	The George Washington University	Methods of preparing epitopes of tumor associated antigens
US5739009A (en) *	1996-12-12	1998-04-14	Incyte Pharmaceuticals, Inc.	Adipocyte-specific differentiation-related protein
US6977074B2 (en) *	1997-07-10	2005-12-20	Mannkind Corporation	Method of inducing a CTL response
DE19837015C2 (de) *	1998-08-14	2003-03-20	Vasopharm Biotech Gmbh	Isolierte und gereinigte humane lösliche Guanylylcyclase alpha1/beta1 (hsGCalpha1/beta1)
DE19936563A1 (de)	1999-08-04	2001-02-08	Boehringer Ingelheim Int	Tumorassoziiertes Antigen
US6809179B1 (en)	1999-08-04	2004-10-26	Boehringer Ingelheim International Gmbh	Tumor-associated antigen (R11)
WO2001063294A2 (en) *	2000-02-24	2001-08-30	Oxford Glycosciences (Uk) Limited	Diagnosis of bipolar affective disorder (bad) and unipolar depression
AU2001295582A1 (en) *	2000-12-20	2002-07-01	GlaxoSmithKline Biologicals (s.a.)	Tumour-related antigens
US20030170719A1 (en) *	2000-12-28	2003-09-11	Akio Matsuda	NF-kappa B activating gene
AU2002309583A1 (en) *	2001-04-18	2002-11-05	Protein Desing Labs, Inc.	Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
US6867283B2 (en) *	2001-05-16	2005-03-15	Technion Research & Development Foundation Ltd.	Peptides capable of binding to MHC molecules, cells presenting such peptides, and pharmaceutical compositions comprising such peptides and/or cells
WO2002101075A2 (en) *	2001-06-13	2002-12-19	Millennium Pharmaceuticals, Inc.	Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
US7244573B2 (en) *	2001-12-03	2007-07-17	Bristol-Myers Squibb Company	Polynucleotides and polypeptides associated with the development of rheumatoid arthritis

2002
- 2002-05-29 DE DE10225144A patent/DE10225144A1/de not_active Ceased
2003
- 2003-03-27 DE DE50310613T patent/DE50310613D1/de not_active Expired - Lifetime
- 2003-03-27 SI SI200331451T patent/SI1734048T1/sl unknown
- 2003-03-27 EP EP06015805A patent/EP1734048B1/de not_active Expired - Lifetime
- 2003-03-27 PT PT06015806T patent/PT1734049E/pt unknown
- 2003-03-27 DK DK03720376T patent/DK1507795T3/da active
- 2003-03-27 ES ES08014305T patent/ES2348468T3/es not_active Expired - Lifetime
- 2003-03-27 ES ES03720376T patent/ES2314196T3/es not_active Expired - Lifetime
- 2003-03-27 DE DE50312701T patent/DE50312701D1/de not_active Expired - Lifetime
- 2003-03-27 PL PL390815A patent/PL211158B1/pl unknown
- 2003-03-27 ES ES08014304T patent/ES2350461T3/es not_active Expired - Lifetime
- 2003-03-27 DE DE50310882T patent/DE50310882D1/de not_active Expired - Lifetime
- 2003-03-27 CA CA2736972A patent/CA2736972C/en not_active Expired - Fee Related
- 2003-03-27 PL PL390814A patent/PL211157B1/pl unknown
- 2003-03-27 DK DK08014304.3T patent/DK2006294T3/da active
- 2003-03-27 PL PL373700A patent/PL206306B1/pl unknown
- 2003-03-27 PT PT06015805T patent/PT1734048E/pt unknown
- 2003-03-27 PT PT08014304T patent/PT2006294E/pt unknown
- 2003-03-27 DK DK06015805T patent/DK1734048T3/da active
- 2003-03-27 CA CA2736974A patent/CA2736974C/en not_active Expired - Fee Related
- 2003-03-27 EP EP08014305A patent/EP2014673B1/de not_active Expired - Lifetime
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- 2003-03-27 PL PL390816A patent/PL210356B1/pl unknown
- 2003-03-27 AT AT06015805T patent/ATE417859T1/de active
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- 2003-03-27 WO PCT/EP2003/003181 patent/WO2003102023A1/de active Application Filing
- 2003-03-27 EP EP06015806A patent/EP1734049B1/de not_active Expired - Lifetime
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2004
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2007
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2008
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2010
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Also Published As

Publication number	Publication date
EP2014673B1 (de)	2010-05-05
ATE466872T1 (de)	2010-05-15
EP1734048A1 (de)	2006-12-20
JP2010088449A (ja)	2010-04-22
ES2350461T3 (es)	2011-01-24
CA2736974C (en)	2014-09-02
PL211157B1 (pl)	2012-04-30
US20050222390A1 (en)	2005-10-06
ES2317378T3 (es)	2009-04-16
US7763711B2 (en)	2010-07-27
EP2014673A1 (de)	2009-01-14
ATE416188T1 (de)	2008-12-15
DE50310882D1 (de)	2009-01-15
ES2317379T3 (es)	2009-04-16
DE50312701D1 (de)	2010-06-17
US20080057077A1 (en)	2008-03-06
US8399613B2 (en)	2013-03-19
DE50313004D1 (de)	2010-09-30
JP2010099080A (ja)	2010-05-06
EP1734048B1 (de)	2008-12-17
JP4472520B2 (ja)	2010-06-02
EP2006294A1 (de)	2008-12-24
EP2006294B1 (de)	2010-08-18
AU2003224001B2 (en)	2010-03-11
CY1110723T1 (el)	2015-06-10
WO2003102023A1 (de)	2003-12-11
AU2003224001A1 (en)	2003-12-19
DK1507795T3 (da)	2008-12-08
SI2014673T1 (sl)	2010-09-30
CA2487137A1 (en)	2003-12-11
JP5042301B2 (ja)	2012-10-03
JP5042300B2 (ja)	2012-10-03
PL373700A1 (en)	2005-09-05
ES2348468T3 (es)	2010-12-07
PT1507795E (pt)	2008-12-26
US20100183644A1 (en)	2010-07-22
ES2314196T3 (es)	2009-03-16
US7666984B2 (en)	2010-02-23
DE50310613D1 (de)	2008-11-20
US7396904B2 (en)	2008-07-08
US20100184211A1 (en)	2010-07-22
PT2014673E (pt)	2010-08-04
CA2736974A1 (en)	2003-12-11
DE50310952D1 (de)	2009-01-29
US8536304B2 (en)	2013-09-17
CA2736972C (en)	2014-08-05
PT1734049E (pt)	2008-12-26
JP5042302B2 (ja)	2012-10-03
CY1108673T1 (el)	2014-04-09
CA2736972A1 (en)	2003-12-11
SI1734048T1 (sl)	2009-02-28
PL211158B1 (pl)	2012-04-30
EP1507795A1 (de)	2005-02-23
DK1734048T3 (da)	2009-02-23
PL206306B1 (pl)	2010-07-30
CY1108507T1 (el)	2014-04-09
JP2010099079A (ja)	2010-05-06
PT2006294E (pt)	2010-11-12
EP1734049A1 (de)	2006-12-20
CA2736921C (en)	2013-09-03
ATE410442T1 (de)	2008-10-15
CA2487137C (en)	2013-02-19
JP2010099078A (ja)	2010-05-06
SI1507795T1 (sl)	2009-04-30
CA2736926A1 (en)	2003-12-11
AU2010200689B2 (en)	2012-07-12
DK1734049T3 (da)	2009-01-19
US20080051347A1 (en)	2008-02-28
JP5042303B2 (ja)	2012-10-03
JP2006511196A (ja)	2006-04-06
CA2736926C (en)	2015-11-17
AU2010200689A1 (en)	2010-03-18
SI1734049T1 (sl)	2009-02-28
PL211159B1 (pl)	2012-04-30
CY1108680T1 (el)	2014-04-09
CA2736921A1 (en)	2003-12-11
CY1111174T1 (el)	2015-06-11
PL210356B1 (pl)	2012-01-31
DE10225144A1 (de)	2003-12-18
EP1507795B1 (de)	2008-10-08
HRP20041108B1 (hr)	2013-11-08
DK2014673T3 (da)	2010-08-30
EP1734049B1 (de)	2008-12-03
SI2006294T1 (sl)	2010-11-30
ATE417859T1 (de)	2009-01-15
PT1734048E (pt)	2009-01-02
ATE478088T1 (de)	2010-09-15
HRP20041108A2 (en)	2005-10-31

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