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DK1948590T3 - Fremgangsmåde til frembringelse af kontrastmidler - Google Patents

Fremgangsmåde til frembringelse af kontrastmidler

Info

Publication number
DK1948590T3
DK1948590T3 DK06792978.6T DK06792978T DK1948590T3 DK 1948590 T3 DK1948590 T3 DK 1948590T3 DK 06792978 T DK06792978 T DK 06792978T DK 1948590 T3 DK1948590 T3 DK 1948590T3
Authority
DK
Denmark
Prior art keywords
contrast agents
compound
formula
producing contrast
producing
Prior art date
Application number
DK06792978.6T
Other languages
English (en)
Inventor
Silvia Ceragioli
Giovanni Luca Ciarciello
Luciano Castiglia
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Application granted granted Critical
Publication of DK1948590T3 publication Critical patent/DK1948590T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK06792978.6T 2005-09-13 2006-08-24 Fremgangsmåde til frembringelse af kontrastmidler DK1948590T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05019852A EP1762563A1 (en) 2005-09-13 2005-09-13 Process for the preparation of contrast agents
PCT/EP2006/065634 WO2007031390A1 (en) 2005-09-13 2006-08-24 Process for the preparation of contrast agents

Publications (1)

Publication Number Publication Date
DK1948590T3 true DK1948590T3 (da) 2010-11-29

Family

ID=35501122

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06792978.6T DK1948590T3 (da) 2005-09-13 2006-08-24 Fremgangsmåde til frembringelse af kontrastmidler

Country Status (17)

Country Link
US (2) US7592482B2 (da)
EP (2) EP1762563A1 (da)
JP (1) JP5108769B2 (da)
KR (1) KR101358058B1 (da)
CN (1) CN101263108B (da)
AT (1) ATE478040T1 (da)
AU (1) AU2006290947B2 (da)
CA (1) CA2621339C (da)
DE (1) DE602006016320D1 (da)
DK (1) DK1948590T3 (da)
ES (1) ES2351166T3 (da)
HR (1) HRP20100565T1 (da)
IL (1) IL189643A (da)
NO (1) NO340308B1 (da)
PL (1) PL1948590T3 (da)
SI (1) SI1948590T1 (da)
WO (1) WO2007031390A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8501988B2 (en) * 2008-04-17 2013-08-06 Ecolab Usa Inc. Synthesis and applications of amino carboxylates
EP2327395A1 (en) * 2009-11-23 2011-06-01 Bracco Imaging S.p.A Process for the preparation of gadobenate dimeglumine complex in a solid form
EP2338874A1 (en) 2009-12-16 2011-06-29 Bracco Imaging S.p.A Process for the preparation of chelated compounds
IT1403988B1 (it) * 2010-07-15 2013-11-08 Bracco Imaging Spa Processo per la preparazione di agenti di contrasto.
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
JP6096798B2 (ja) * 2011-11-25 2017-03-15 バイオフォア インディア ファーマシューティカルズ プライベート リミテッド ポリアミノカルボキシレートキレート剤の精製方法
CN102603550B (zh) * 2012-02-16 2014-11-26 佛山普正医药科技有限公司 一种中间体bopta的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2086445T3 (es) * 1987-07-16 1996-07-01 Nycomed Imaging As Acidos aminocarboxilicos y sus derivados.
WO1994027644A1 (en) * 1993-06-02 1994-12-08 Bracco S.P.A. Iodinated paramagnetic chelates, and their use as contrast agents
IT1291624B1 (it) * 1997-04-18 1999-01-11 Bracco Spa Chelati complessi di metalli paramagnetici a bassa tossicita'
ITMI981583A1 (it) * 1998-07-10 2000-01-10 Bracco Spa Processo per la preparazione dell'acido 4 -carbossi-5,8,11-tris (carbossimetil)-1-fenil-2-oxa-5,8,11-triazatridecan-13-oico
JP5004438B2 (ja) * 2005-06-09 2012-08-22 行政院原子能委員会核能研究所 Dtpa誘導体の製造方法

Also Published As

Publication number Publication date
IL189643A (en) 2012-03-29
CA2621339C (en) 2011-04-26
NO340308B1 (no) 2017-03-27
DE602006016320D1 (da) 2010-09-30
SI1948590T1 (sl) 2010-12-31
KR20080045724A (ko) 2008-05-23
US20090118537A1 (en) 2009-05-07
PL1948590T3 (pl) 2011-03-31
AU2006290947B2 (en) 2012-01-19
ATE478040T1 (de) 2010-09-15
EP1948590B1 (en) 2010-08-18
CA2621339A1 (en) 2007-03-22
EP1948590A1 (en) 2008-07-30
EP1762563A1 (en) 2007-03-14
US20090306424A1 (en) 2009-12-10
JP2009507882A (ja) 2009-02-26
CN101263108B (zh) 2011-12-21
JP5108769B2 (ja) 2012-12-26
AU2006290947A1 (en) 2007-03-22
HRP20100565T1 (hr) 2010-11-30
CN101263108A (zh) 2008-09-10
NO20081655L (no) 2008-04-09
ES2351166T3 (es) 2011-02-01
KR101358058B1 (ko) 2014-02-06
WO2007031390A1 (en) 2007-03-22
US7592482B2 (en) 2009-09-22

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