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DK1689777T3 - Fremgangsmåde til oprensning af il18-bindende protein - Google Patents

Fremgangsmåde til oprensning af il18-bindende protein

Info

Publication number
DK1689777T3
DK1689777T3 DK04798163T DK04798163T DK1689777T3 DK 1689777 T3 DK1689777 T3 DK 1689777T3 DK 04798163 T DK04798163 T DK 04798163T DK 04798163 T DK04798163 T DK 04798163T DK 1689777 T3 DK1689777 T3 DK 1689777T3
Authority
DK
Denmark
Prior art keywords
binding protein
purifying
purification
fluid
relates
Prior art date
Application number
DK04798163T
Other languages
Danish (da)
English (en)
Inventor
Mara Rossi
Thierry Ziegler
Laure Valognes
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of DK1689777T3 publication Critical patent/DK1689777T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK04798163T 2003-11-05 2004-11-04 Fremgangsmåde til oprensning af il18-bindende protein DK1689777T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51744703P 2003-11-05 2003-11-05
EP03104092 2003-11-05
PCT/EP2004/052807 WO2005049649A1 (en) 2003-11-05 2004-11-04 Process for the purification of il-18 binding protein

Publications (1)

Publication Number Publication Date
DK1689777T3 true DK1689777T3 (da) 2007-06-11

Family

ID=34924126

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04798163T DK1689777T3 (da) 2003-11-05 2004-11-04 Fremgangsmåde til oprensning af il18-bindende protein

Country Status (19)

Country Link
US (1) US7820800B2 (ja)
EP (1) EP1689777B1 (ja)
JP (1) JP4741504B2 (ja)
AT (1) ATE360647T1 (ja)
AU (1) AU2004291341B2 (ja)
CA (1) CA2544146C (ja)
CY (1) CY1106683T1 (ja)
DE (1) DE602004006157T2 (ja)
DK (1) DK1689777T3 (ja)
ES (1) ES2285543T3 (ja)
HR (1) HRP20070196T3 (ja)
IL (1) IL175431A (ja)
ME (1) ME01198B (ja)
NO (1) NO330538B1 (ja)
PL (1) PL1689777T3 (ja)
PT (1) PT1689777E (ja)
RS (1) RS50516B (ja)
SI (1) SI1689777T1 (ja)
WO (1) WO2005049649A1 (ja)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2309508T3 (es) * 2003-03-11 2008-12-16 Laboratoires Serono Sa Vectores de expresion que comprenden el promotor de mcmv-ie2.
JP5074030B2 (ja) * 2003-05-13 2012-11-14 メルク セローノ ソシエテ アノニム Il−18結合タンパク質の活性変異体とその医学的応用
ES2354160T3 (es) * 2003-10-21 2011-03-10 Merck Serono Sa Secuencia de adn mínima que actúa como un aislante de cromatina, y su uso en la expresión de proteínas.
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
PL1720979T3 (pl) 2004-03-01 2008-03-31 Ares Trading Sa Zastosowanie podłoża pozbawionego surowicy do hodowli komórkowej do wytwarzania IL-18BP w komórkach ssaków
WO2006003134A1 (en) 2004-06-29 2006-01-12 Ares Trading S.A. Process for the purification of il-18 binding protein
JP2008535913A (ja) * 2005-04-11 2008-09-04 メダレックス インコーポレーティッド タンパク質精製方法
EP2267024B1 (en) * 2005-06-03 2012-05-09 Ares Trading S.A. Production of recombinant Il-18 binding protein
DK1891088T3 (da) * 2005-06-10 2012-01-30 Ares Trading Sa Fremgangsmåde til rensning af et IL-18-bindende protein
US9096651B2 (en) 2007-09-26 2015-08-04 Chugai Seiyaku Kabushiki Kaisha Method of modifying isoelectric point of antibody via amino acid substitution in CDR
JP5944101B2 (ja) 2008-01-18 2016-07-05 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 非グリコシル化タンパク質の精製
JP4954326B2 (ja) * 2008-04-11 2012-06-13 中外製薬株式会社 複数分子の抗原に繰り返し結合する抗原結合分子
TWI440469B (zh) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
WO2011156369A2 (en) * 2010-06-07 2011-12-15 Dr. Reddy's Laboratories Ltd. Purification of modified cytokines
SG190727A1 (en) 2010-11-30 2013-07-31 Chugai Pharmaceutical Co Ltd Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
JP6032818B2 (ja) 2011-02-25 2016-11-30 中外製薬株式会社 FcγRIIb特異的Fc抗体
SG193545A1 (en) 2011-03-29 2013-11-29 Glaxosmithkline Llc Buffer system for protein purification
TW201817745A (zh) 2011-09-30 2018-05-16 日商中外製藥股份有限公司 具有促進抗原清除之FcRn結合域的治療性抗原結合分子
US20150050269A1 (en) 2011-09-30 2015-02-19 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities
BR112014013081A2 (pt) 2011-11-30 2020-10-20 Chugai Seiyaku Kabushiki Kaisha veículo contendo fármaco em célula para formação de um complexo imune
AU2014250434B2 (en) 2013-04-02 2019-08-08 Chugai Seiyaku Kabushiki Kaisha Fc region variant
PT3116891T (pt) * 2014-03-10 2020-05-18 Richter Gedeon Nyrt Purificação de imunoglobulina utilizando passos de pré-limpeza
CN107001411B (zh) * 2014-12-15 2021-07-23 默克专利股份公司 从粗溶液捕获靶分子
RU2746356C2 (ru) 2014-12-19 2021-04-12 Чугаи Сейяку Кабусики Кайся Антитела к с5 и способы их применения
TW202432590A (zh) 2014-12-19 2024-08-16 日商中外製藥股份有限公司 抗肌抑素之抗體、含變異Fc區域之多胜肽及使用方法
CN114773469A (zh) 2015-02-05 2022-07-22 中外制药株式会社 包含离子浓度依赖性的抗原结合结构域的抗体,fc区变体,il-8-结合抗体及其应用
CA2972393A1 (en) 2015-02-27 2016-09-01 Chugai Seiyaku Kabushiki Kaisha Composition for treating il-6-related diseases
US11359009B2 (en) 2015-12-25 2022-06-14 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
KR20230079499A (ko) 2016-08-05 2023-06-07 추가이 세이야쿠 가부시키가이샤 Il-8 관련 질환의 치료용 또는 예방용 조성물
EP3574010A4 (en) 2017-01-30 2020-12-16 Chugai Seiyaku Kabushiki Kaisha ANTI-SCLEROSTIN ANTIBODIES AND METHOD OF USE
WO2018203545A1 (ja) 2017-05-02 2018-11-08 国立研究開発法人国立精神・神経医療研究センター Il-6及び好中球の関連する疾患の治療効果の予測及び判定方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
WO2000012555A1 (fr) 1998-09-01 2000-03-09 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Proteine de liaison de l'interleukine 18
JP4216950B2 (ja) * 1998-09-01 2009-01-28 株式会社林原生物化学研究所 インターロイキン−18結合蛋白質
US20020052475A1 (en) * 2000-07-20 2002-05-02 Schering Ag High affinity soluble interleukin-18 receptor
JP2004530432A (ja) * 2001-03-08 2004-10-07 アレス・トレーディング・ソシエテ・アノニム インターロイキン−18変異体、その産生および使用
MEP32608A (en) * 2001-06-26 2011-02-10 Amgen Fremont Inc Antibodies to opgl
JP2006512891A (ja) * 2002-04-18 2006-04-20 ジェネンコー・インターナショナル・インク 糸状菌における機能性抗体の生産
ES2309508T3 (es) 2003-03-11 2008-12-16 Laboratoires Serono Sa Vectores de expresion que comprenden el promotor de mcmv-ie2.
JP5074030B2 (ja) 2003-05-13 2012-11-14 メルク セローノ ソシエテ アノニム Il−18結合タンパク質の活性変異体とその医学的応用
ES2354160T3 (es) 2003-10-21 2011-03-10 Merck Serono Sa Secuencia de adn mínima que actúa como un aislante de cromatina, y su uso en la expresión de proteínas.
PL1720979T3 (pl) 2004-03-01 2008-03-31 Ares Trading Sa Zastosowanie podłoża pozbawionego surowicy do hodowli komórkowej do wytwarzania IL-18BP w komórkach ssaków
WO2006003134A1 (en) 2004-06-29 2006-01-12 Ares Trading S.A. Process for the purification of il-18 binding protein
EP2267024B1 (en) * 2005-06-03 2012-05-09 Ares Trading S.A. Production of recombinant Il-18 binding protein
DK1891088T3 (da) 2005-06-10 2012-01-30 Ares Trading Sa Fremgangsmåde til rensning af et IL-18-bindende protein

Also Published As

Publication number Publication date
IL175431A (en) 2011-02-28
HRP20070196T3 (en) 2007-06-30
ATE360647T1 (de) 2007-05-15
DE602004006157D1 (de) 2007-06-06
ES2285543T3 (es) 2007-11-16
PL1689777T3 (pl) 2007-09-28
AU2004291341B2 (en) 2010-08-05
IL175431A0 (en) 2006-09-05
EP1689777A1 (en) 2006-08-16
ME01198B (me) 2013-03-20
PT1689777E (pt) 2007-05-31
EP1689777B1 (en) 2007-04-25
NO330538B1 (no) 2011-05-09
AU2004291341A1 (en) 2005-06-02
SI1689777T1 (sl) 2007-08-31
NO20062545L (no) 2006-08-03
RS50516B (sr) 2010-05-07
CA2544146C (en) 2012-10-02
CA2544146A1 (en) 2005-06-02
JP2007533651A (ja) 2007-11-22
US7820800B2 (en) 2010-10-26
DE602004006157T2 (de) 2008-01-03
CY1106683T1 (el) 2012-05-23
JP4741504B2 (ja) 2011-08-03
US20070037734A1 (en) 2007-02-15
WO2005049649A1 (en) 2005-06-02

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