DK1689777T3 - Fremgangsmåde til oprensning af il18-bindende protein - Google Patents
Fremgangsmåde til oprensning af il18-bindende proteinInfo
- Publication number
- DK1689777T3 DK1689777T3 DK04798163T DK04798163T DK1689777T3 DK 1689777 T3 DK1689777 T3 DK 1689777T3 DK 04798163 T DK04798163 T DK 04798163T DK 04798163 T DK04798163 T DK 04798163T DK 1689777 T3 DK1689777 T3 DK 1689777T3
- Authority
- DK
- Denmark
- Prior art keywords
- binding protein
- purifying
- purification
- fluid
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51744703P | 2003-11-05 | 2003-11-05 | |
EP03104092 | 2003-11-05 | ||
PCT/EP2004/052807 WO2005049649A1 (en) | 2003-11-05 | 2004-11-04 | Process for the purification of il-18 binding protein |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1689777T3 true DK1689777T3 (da) | 2007-06-11 |
Family
ID=34924126
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04798163T DK1689777T3 (da) | 2003-11-05 | 2004-11-04 | Fremgangsmåde til oprensning af il18-bindende protein |
Country Status (19)
Country | Link |
---|---|
US (1) | US7820800B2 (ja) |
EP (1) | EP1689777B1 (ja) |
JP (1) | JP4741504B2 (ja) |
AT (1) | ATE360647T1 (ja) |
AU (1) | AU2004291341B2 (ja) |
CA (1) | CA2544146C (ja) |
CY (1) | CY1106683T1 (ja) |
DE (1) | DE602004006157T2 (ja) |
DK (1) | DK1689777T3 (ja) |
ES (1) | ES2285543T3 (ja) |
HR (1) | HRP20070196T3 (ja) |
IL (1) | IL175431A (ja) |
ME (1) | ME01198B (ja) |
NO (1) | NO330538B1 (ja) |
PL (1) | PL1689777T3 (ja) |
PT (1) | PT1689777E (ja) |
RS (1) | RS50516B (ja) |
SI (1) | SI1689777T1 (ja) |
WO (1) | WO2005049649A1 (ja) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2309508T3 (es) * | 2003-03-11 | 2008-12-16 | Laboratoires Serono Sa | Vectores de expresion que comprenden el promotor de mcmv-ie2. |
JP5074030B2 (ja) * | 2003-05-13 | 2012-11-14 | メルク セローノ ソシエテ アノニム | Il−18結合タンパク質の活性変異体とその医学的応用 |
ES2354160T3 (es) * | 2003-10-21 | 2011-03-10 | Merck Serono Sa | Secuencia de adn mínima que actúa como un aislante de cromatina, y su uso en la expresión de proteínas. |
US7968684B2 (en) | 2003-11-12 | 2011-06-28 | Abbott Laboratories | IL-18 binding proteins |
PL1720979T3 (pl) | 2004-03-01 | 2008-03-31 | Ares Trading Sa | Zastosowanie podłoża pozbawionego surowicy do hodowli komórkowej do wytwarzania IL-18BP w komórkach ssaków |
WO2006003134A1 (en) | 2004-06-29 | 2006-01-12 | Ares Trading S.A. | Process for the purification of il-18 binding protein |
JP2008535913A (ja) * | 2005-04-11 | 2008-09-04 | メダレックス インコーポレーティッド | タンパク質精製方法 |
EP2267024B1 (en) * | 2005-06-03 | 2012-05-09 | Ares Trading S.A. | Production of recombinant Il-18 binding protein |
DK1891088T3 (da) * | 2005-06-10 | 2012-01-30 | Ares Trading Sa | Fremgangsmåde til rensning af et IL-18-bindende protein |
US9096651B2 (en) | 2007-09-26 | 2015-08-04 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substitution in CDR |
JP5944101B2 (ja) | 2008-01-18 | 2016-07-05 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 非グリコシル化タンパク質の精製 |
JP4954326B2 (ja) * | 2008-04-11 | 2012-06-13 | 中外製薬株式会社 | 複数分子の抗原に繰り返し結合する抗原結合分子 |
TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
WO2011156369A2 (en) * | 2010-06-07 | 2011-12-15 | Dr. Reddy's Laboratories Ltd. | Purification of modified cytokines |
SG190727A1 (en) | 2010-11-30 | 2013-07-31 | Chugai Pharmaceutical Co Ltd | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
JP6032818B2 (ja) | 2011-02-25 | 2016-11-30 | 中外製薬株式会社 | FcγRIIb特異的Fc抗体 |
SG193545A1 (en) | 2011-03-29 | 2013-11-29 | Glaxosmithkline Llc | Buffer system for protein purification |
TW201817745A (zh) | 2011-09-30 | 2018-05-16 | 日商中外製藥股份有限公司 | 具有促進抗原清除之FcRn結合域的治療性抗原結合分子 |
US20150050269A1 (en) | 2011-09-30 | 2015-02-19 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities |
BR112014013081A2 (pt) | 2011-11-30 | 2020-10-20 | Chugai Seiyaku Kabushiki Kaisha | veículo contendo fármaco em célula para formação de um complexo imune |
AU2014250434B2 (en) | 2013-04-02 | 2019-08-08 | Chugai Seiyaku Kabushiki Kaisha | Fc region variant |
PT3116891T (pt) * | 2014-03-10 | 2020-05-18 | Richter Gedeon Nyrt | Purificação de imunoglobulina utilizando passos de pré-limpeza |
CN107001411B (zh) * | 2014-12-15 | 2021-07-23 | 默克专利股份公司 | 从粗溶液捕获靶分子 |
RU2746356C2 (ru) | 2014-12-19 | 2021-04-12 | Чугаи Сейяку Кабусики Кайся | Антитела к с5 и способы их применения |
TW202432590A (zh) | 2014-12-19 | 2024-08-16 | 日商中外製藥股份有限公司 | 抗肌抑素之抗體、含變異Fc區域之多胜肽及使用方法 |
CN114773469A (zh) | 2015-02-05 | 2022-07-22 | 中外制药株式会社 | 包含离子浓度依赖性的抗原结合结构域的抗体,fc区变体,il-8-结合抗体及其应用 |
CA2972393A1 (en) | 2015-02-27 | 2016-09-01 | Chugai Seiyaku Kabushiki Kaisha | Composition for treating il-6-related diseases |
US11359009B2 (en) | 2015-12-25 | 2022-06-14 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
KR20230079499A (ko) | 2016-08-05 | 2023-06-07 | 추가이 세이야쿠 가부시키가이샤 | Il-8 관련 질환의 치료용 또는 예방용 조성물 |
EP3574010A4 (en) | 2017-01-30 | 2020-12-16 | Chugai Seiyaku Kabushiki Kaisha | ANTI-SCLEROSTIN ANTIBODIES AND METHOD OF USE |
WO2018203545A1 (ja) | 2017-05-02 | 2018-11-08 | 国立研究開発法人国立精神・神経医療研究センター | Il-6及び好中球の関連する疾患の治療効果の予測及び判定方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL121860A0 (en) * | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
WO2000012555A1 (fr) | 1998-09-01 | 2000-03-09 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Proteine de liaison de l'interleukine 18 |
JP4216950B2 (ja) * | 1998-09-01 | 2009-01-28 | 株式会社林原生物化学研究所 | インターロイキン−18結合蛋白質 |
US20020052475A1 (en) * | 2000-07-20 | 2002-05-02 | Schering Ag | High affinity soluble interleukin-18 receptor |
JP2004530432A (ja) * | 2001-03-08 | 2004-10-07 | アレス・トレーディング・ソシエテ・アノニム | インターロイキン−18変異体、その産生および使用 |
MEP32608A (en) * | 2001-06-26 | 2011-02-10 | Amgen Fremont Inc | Antibodies to opgl |
JP2006512891A (ja) * | 2002-04-18 | 2006-04-20 | ジェネンコー・インターナショナル・インク | 糸状菌における機能性抗体の生産 |
ES2309508T3 (es) | 2003-03-11 | 2008-12-16 | Laboratoires Serono Sa | Vectores de expresion que comprenden el promotor de mcmv-ie2. |
JP5074030B2 (ja) | 2003-05-13 | 2012-11-14 | メルク セローノ ソシエテ アノニム | Il−18結合タンパク質の活性変異体とその医学的応用 |
ES2354160T3 (es) | 2003-10-21 | 2011-03-10 | Merck Serono Sa | Secuencia de adn mínima que actúa como un aislante de cromatina, y su uso en la expresión de proteínas. |
PL1720979T3 (pl) | 2004-03-01 | 2008-03-31 | Ares Trading Sa | Zastosowanie podłoża pozbawionego surowicy do hodowli komórkowej do wytwarzania IL-18BP w komórkach ssaków |
WO2006003134A1 (en) | 2004-06-29 | 2006-01-12 | Ares Trading S.A. | Process for the purification of il-18 binding protein |
EP2267024B1 (en) * | 2005-06-03 | 2012-05-09 | Ares Trading S.A. | Production of recombinant Il-18 binding protein |
DK1891088T3 (da) | 2005-06-10 | 2012-01-30 | Ares Trading Sa | Fremgangsmåde til rensning af et IL-18-bindende protein |
-
2004
- 2004-11-04 RS RSP-2007/0216A patent/RS50516B/sr unknown
- 2004-11-04 US US10/576,372 patent/US7820800B2/en not_active Expired - Lifetime
- 2004-11-04 ME MEP-2008-580A patent/ME01198B/me unknown
- 2004-11-04 SI SI200430322T patent/SI1689777T1/sl unknown
- 2004-11-04 AU AU2004291341A patent/AU2004291341B2/en not_active Expired
- 2004-11-04 DK DK04798163T patent/DK1689777T3/da active
- 2004-11-04 PL PL04798163T patent/PL1689777T3/pl unknown
- 2004-11-04 WO PCT/EP2004/052807 patent/WO2005049649A1/en active Application Filing
- 2004-11-04 EP EP04798163A patent/EP1689777B1/en not_active Expired - Lifetime
- 2004-11-04 PT PT04798163T patent/PT1689777E/pt unknown
- 2004-11-04 ES ES04798163T patent/ES2285543T3/es not_active Expired - Lifetime
- 2004-11-04 CA CA2544146A patent/CA2544146C/en not_active Expired - Lifetime
- 2004-11-04 AT AT04798163T patent/ATE360647T1/de active
- 2004-11-04 JP JP2006537319A patent/JP4741504B2/ja not_active Expired - Lifetime
- 2004-11-04 DE DE602004006157T patent/DE602004006157T2/de not_active Expired - Lifetime
-
2006
- 2006-05-04 IL IL175431A patent/IL175431A/en active IP Right Grant
- 2006-06-02 NO NO20062545A patent/NO330538B1/no unknown
-
2007
- 2007-05-07 HR HR20070196T patent/HRP20070196T3/xx unknown
- 2007-06-28 CY CY20071100852T patent/CY1106683T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
IL175431A (en) | 2011-02-28 |
HRP20070196T3 (en) | 2007-06-30 |
ATE360647T1 (de) | 2007-05-15 |
DE602004006157D1 (de) | 2007-06-06 |
ES2285543T3 (es) | 2007-11-16 |
PL1689777T3 (pl) | 2007-09-28 |
AU2004291341B2 (en) | 2010-08-05 |
IL175431A0 (en) | 2006-09-05 |
EP1689777A1 (en) | 2006-08-16 |
ME01198B (me) | 2013-03-20 |
PT1689777E (pt) | 2007-05-31 |
EP1689777B1 (en) | 2007-04-25 |
NO330538B1 (no) | 2011-05-09 |
AU2004291341A1 (en) | 2005-06-02 |
SI1689777T1 (sl) | 2007-08-31 |
NO20062545L (no) | 2006-08-03 |
RS50516B (sr) | 2010-05-07 |
CA2544146C (en) | 2012-10-02 |
CA2544146A1 (en) | 2005-06-02 |
JP2007533651A (ja) | 2007-11-22 |
US7820800B2 (en) | 2010-10-26 |
DE602004006157T2 (de) | 2008-01-03 |
CY1106683T1 (el) | 2012-05-23 |
JP4741504B2 (ja) | 2011-08-03 |
US20070037734A1 (en) | 2007-02-15 |
WO2005049649A1 (en) | 2005-06-02 |
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