DK1660041T3 - Ikke-polær fotosensibilisator til fotodynamisk terapi - Google Patents

Ikke-polær fotosensibilisator til fotodynamisk terapi

Info

Publication number: DK1660041T3
Authority: DK; Denmark
Prior art keywords: photodynamic therapy; polar photosensitizer; photosensitizer; polar; photodynamic
Prior art date: 2003-08-26

Application number

DK04776989.8T

Other languages

English (en)

Inventor

Volker Albrecht

Alfred Fahr

Susanna Graefe

Wolfgang Neuberger

Dietrich Scheglmann

Original Assignee

Biolitec Pharma Marketing Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-08-26

Filing date

2004-06-23

Publication date

2013-06-03

2004-06-23 Application filed by Biolitec Pharma Marketing Ltd filed Critical Biolitec Pharma Marketing Ltd

2013-06-03 Application granted granted Critical

2013-06-03 Publication of DK1660041T3 publication Critical patent/DK1660041T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Reproductive Health (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Endocrinology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK04776989.8T 2003-08-26 2004-06-23 Ikke-polær fotosensibilisator til fotodynamisk terapi DK1660041T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10/648,168 US20050048109A1 (en)	2003-08-26	2003-08-26	Non-polar photosensitizer formulations for photodynamic therapy
PCT/US2004/020163 WO2005023220A1 (en)	2003-08-26	2004-06-23	Non-polar photosensitizer formulations for photodynamic therapy

Publications (1)

Publication Number	Publication Date
DK1660041T3 true DK1660041T3 (da)	2013-06-03

Family

ID=34216686

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK12161556.1T DK2471512T3 (da)	2003-08-26	2004-06-23	Ikke-polær fotosensibilisatorformuleringer til fotodynamisk terapi
DK04776989.8T DK1660041T3 (da)	2003-08-26	2004-06-23	Ikke-polær fotosensibilisator til fotodynamisk terapi

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK12161556.1T DK2471512T3 (da)	2003-08-26	2004-06-23	Ikke-polær fotosensibilisatorformuleringer til fotodynamisk terapi

Country Status (16)

Country	Link
US (3)	US20050048109A1 (da)
EP (2)	EP2471512B1 (da)
JP (2)	JP4869929B2 (da)
KR (3)	KR100975160B1 (da)
CN (1)	CN1842322B (da)
AU (1)	AU2004270119B2 (da)
BR (1)	BRPI0413889A (da)
CA (2)	CA2746516C (da)
DK (2)	DK2471512T3 (da)
ES (2)	ES2403601T3 (da)
HU (1)	HUE026790T2 (da)
IL (2)	IL173808A (da)
PL (2)	PL2471512T3 (da)
PT (1)	PT1660041E (da)
RU (1)	RU2343904C2 (da)
WO (1)	WO2005023220A1 (da)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7968115B2 (en) *	2004-03-05	2011-06-28	Board Of Regents, The University Of Texas System	Liposomal curcumin for treatment of cancer
US20050048109A1 (en) *	2003-08-26	2005-03-03	Ceramoptec Industries, Inc.	Non-polar photosensitizer formulations for photodynamic therapy
US8986731B2 (en) *	2003-08-26	2015-03-24	Biolitec Pharma Marketing Ltd	Pegylated liposomal formulations of hydrophobic photosensitizers for photodynamic therapy
US8784881B2 (en)	2004-03-05	2014-07-22	Board Of Regents, The University Of Texas System	Liposomal curcumin for treatment of diseases
US20080103213A1 (en) *	2004-03-05	2008-05-01	Board Of Regents, The University Of Texas System	Liposomal curcumin for treatment of neurofibromatosis
JPWO2006121199A1 (ja) *	2005-05-11	2008-12-18	日本ケミカルリサーチ株式会社	脂質小胞体組成物
US20070031482A1 (en) *	2005-08-02	2007-02-08	Ceramoptec Industries, Ind.	PDT treatment method for cellulites and cosmetic use
US8999933B2 (en) *	2006-01-18	2015-04-07	Biolitec Pharma Marketing Ltd	Photodynamic cosmetic procedure and healing method
TW200738278A (en) *	2006-04-03	2007-10-16	Univ Taipei Medical	A liposome combination and the use thereof
US20090081281A1 (en) *	2006-05-10	2009-03-26	Gerard Farmer	Photosensitizer Formulation for Topical Applications
US20080275432A1 (en) *	2006-05-11	2008-11-06	Ceramoptec Industries, Inc.	Photodynamic foam composition and sclerosis treatment
WO2007136633A2 (en) *	2006-05-18	2007-11-29	Ceramoptec Industries, Inc.	Gel-formulations of hydrophobic photosensitizers for mucosal applications
CZ298978B6 (cs) *	2006-11-28	2008-03-26	Fyziologický ústav AV CR	Liposomální gelový ftalocyaninový prípravek pro fotodynamickou terapii nádorových onemocnení a zpusob jeho prípravy
US20090162423A1 (en) *	2007-12-20	2009-06-25	Ceramoptec Industries, Inc.	Formulations for cosmetic and wound care treatments with photosensitizes as fluorescent markers
US20080214460A1 (en) *	2007-01-18	2008-09-04	Ceramoptec Industries, Inc.	Formulations for cosmetic and wound care treatments with photosensitizers as fluorescent markers
WO2008088037A1 (ja) *	2007-01-18	2008-07-24	National University Corporation Chiba University	微粒子製剤
US20110034854A1 (en) *	2007-11-20	2011-02-10	Ceramoptec Industries, Inc.	Pdt assisted vision correction and scar prevention
CN102159569B (zh)	2008-09-18	2016-02-03	拜莱泰克制药市场有限公司	用于pdt的不对称内消旋取代的卟啉和二氢卟酚及其应用
US8815931B2 (en) *	2009-04-28	2014-08-26	Biolitec Pharma Marketing Ltd	Oral formulations for tetrapyrrole derivatives
US20110275686A1 (en) *	2009-12-11	2011-11-10	Biolitec, Inc.	Nanoparticle carrier systems based on poly(dl-lactic-co-glycolic acid) (plga) for photodynamic therapy (pdt)
RU2428981C1 (ru) *	2010-03-31	2011-09-20	Анатолий Юрьевич Барышников	Средство для фотодинамической терапии, способ получения предлагаемого средства и способ проведения фотодинамической терапии с использованием предлагаемого средства
RU2446842C2 (ru) *	2010-07-15	2012-04-10	Учреждение Российской академии наук Центральная клиническая больница РАН	Способ лечения местнораспространенных онкологических заболеваний в эксперименте
CN102432755B (zh) *	2011-09-05	2013-11-13	苏州大学	多重靶向性的光动力学疗法聚合物载体及其制备方法
CA2917545C (en)	2013-07-12	2022-01-11	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Photoactivatable lipid-based nanoparticles as vehicles for dual agent delivery
WO2016051361A1 (en)	2014-09-30	2016-04-07	Biolitec Unternehmensbeteiligungs Ii Ag	Specifically meso-substituted porphyrins and chlorins for photodynamic therapy
JP5995207B2 (ja) *	2014-11-28	2016-09-21	学校法人学習院	含ホウ素ポルフィリン誘導体
CN105311632A (zh) *	2015-10-27	2016-02-10	浙江大学	负载光动力治疗药物的细胞膜微囊的制备方法
EP3210626B1 (en)	2016-02-26	2024-11-27	biolitec Holding GmbH & Co KG	Conjugates of porphyrinoid photosensitizers and glycerol-based polymers for photodynamic therapy
CZ307681B6 (cs)	2016-02-29	2019-02-13	Ústav makromolekulární chemie AV ČR, v. v. i.	Fotoaktivovatelná nanočástice pro fotodynamické aplikace, způsob její přípravy, farmaceutická kompozice ji obsahující a jejich použití
CN106421810B (zh) *	2016-09-26	2019-08-20	武汉大学	一种肿瘤靶向细胞药物载体及其应用
EP3820525A1 (en)	2018-07-12	2021-05-19	The United States of America, as represented by the Secretary, Department of Health and Human Services	Binary lipid bilayer-containing vesicles comprising embedded cytotoxic agents and methods of making and using the same
US20220025185A1 (en)	2018-12-10	2022-01-27	Universitat Hamburg	Specifically glyco-substituted porphyrins and chlorins for photodynamic therapy
KR102203483B1 (ko) *	2018-12-28	2021-01-14	서울대학교산학협력단	방사성 금속 및 유로피움을 포함하는 광역동 요법용 조성물

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB214525A (en) *	1923-09-13	1924-04-24	Ella Martin	Improvements in terminals for electric cables
US4649151A (en) *	1982-09-27	1987-03-10	Health Research, Inc.	Drugs comprising porphyrins
IL69720A (en) *	1983-09-14	1987-08-31	Univ Ramot	Anti-tumor pharmaceutical compositions comprising liposome-bound porphyrins
US5190761A (en) *	1986-08-05	1993-03-02	Liburdy Robert P	Electromagnetic field triggered drug and chemical delivery via liposomes
US5162519A (en) *	1988-03-11	1992-11-10	Efamol Holdings Plc	Porphyrins and cancer treatment
GB8805849D0 (en) *	1988-03-11	1988-04-13	Efamol Holdings	Porphyrins & cancer treatment
JP3037994B2 (ja) *	1989-11-02	2000-05-08	テルモ株式会社	リポソーム表面への蛋白質吸着抑制剤
CA2047969A1 (en) *	1990-08-17	1992-02-18	Thomas D. Madden	Benzoporphyrin vesicles
CA2087902C (en) *	1992-02-05	2006-10-17	Narendra Raghunathji Desai	Liposome compositions of porphyrin photosensitizers
US6890555B1 (en)	1992-02-05	2005-05-10	Qlt, Inc.	Liposome compositions of porphyrin photosensitizers
PT784470E (pt) *	1994-10-03	2003-12-31	Infectio Recherche Inc	Formulacoes de lipossomas para tratamento de doencas virais
US6974666B1 (en) *	1994-10-21	2005-12-13	Appymetric, Inc.	Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US5935942A (en) *	1994-12-14	1999-08-10	Zeimer; Ran	Selective and non-invasive visualization or treatment of vasculature
US5789433A (en) *	1995-01-17	1998-08-04	Quadra Logic Technologies, Inc.	Green porphyrins as immunomodulators
US5707608A (en) *	1995-08-02	1998-01-13	Qlt Phototherapeutics, Inc.	Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizer
US5756541A (en) *	1996-03-11	1998-05-26	Qlt Phototherapeutics Inc	Vision through photodynamic therapy of the eye
US6043237A (en) *	1996-12-10	2000-03-28	Qlt Phototherapeutics, Inc.	Use of photodynamic therapy for prevention of secondary cataracts
IL131776A0 (en) *	1997-03-10	2001-03-19	Res Dev Foundation	Photodynamic therapy generated oxidative stress for temporal and selective expression of heterologous genes
US6010890A (en) *	1997-04-29	2000-01-04	New York Blood Center, Inc.	Method for viral inactivation and compositions for use in same
GB9710049D0 (en) *	1997-05-19	1997-07-09	Nycomed Imaging As	Method
JP4444385B2 (ja) *	1999-02-25	2010-03-31	帝人株式会社	リポソーム用時調製用キット
EP1206288B1 (en) *	1999-08-02	2007-01-10	The Regents Of The University Of Michigan	Targeted fiberless radiative effectors
ATE341310T1 (de) *	2000-02-04	2006-10-15	Lipoxen Technologies Ltd	Dehydratisierungs-/rehydratisierungsverfahren zur herstellung von liposome
GB0005855D0 (en) *	2000-03-10	2000-05-03	Scotia Holdings Plc	Compounds for pdt
WO2001085213A2 (en) *	2000-05-08	2001-11-15	The University Of British Columbia	Supports for photosensitizer formulations
JP2001348341A (ja) *	2000-06-06	2001-12-18	Terumo Corp	低酸素状態の細胞および組織に有効な人工酸素運搬体
US20050048109A1 (en) *	2003-08-26	2005-03-03	Ceramoptec Industries, Inc.	Non-polar photosensitizer formulations for photodynamic therapy

2003
- 2003-08-26 US US10/648,168 patent/US20050048109A1/en not_active Abandoned
2004
- 2004-06-23 JP JP2006524628A patent/JP4869929B2/ja not_active Expired - Fee Related
- 2004-06-23 KR KR1020087006556A patent/KR100975160B1/ko not_active Expired - Fee Related
- 2004-06-23 KR KR1020067003995A patent/KR100887785B1/ko not_active Expired - Fee Related
- 2004-06-23 DK DK12161556.1T patent/DK2471512T3/da active
- 2004-06-23 PT PT47769898T patent/PT1660041E/pt unknown
- 2004-06-23 RU RU2006109497/15A patent/RU2343904C2/ru not_active IP Right Cessation
- 2004-06-23 HU HUE12161556A patent/HUE026790T2/en unknown
- 2004-06-23 CA CA2746516A patent/CA2746516C/en not_active Expired - Fee Related
- 2004-06-23 CN CN2004800244528A patent/CN1842322B/zh not_active Expired - Fee Related
- 2004-06-23 KR KR1020087028533A patent/KR100973064B1/ko not_active Expired - Fee Related
- 2004-06-23 PL PL12161556T patent/PL2471512T3/pl unknown
- 2004-06-23 AU AU2004270119A patent/AU2004270119B2/en not_active Ceased
- 2004-06-23 PL PL04776989T patent/PL1660041T3/pl unknown
- 2004-06-23 EP EP12161556.1A patent/EP2471512B1/en not_active Expired - Lifetime
- 2004-06-23 CA CA2536977A patent/CA2536977C/en not_active Expired - Fee Related
- 2004-06-23 DK DK04776989.8T patent/DK1660041T3/da active
- 2004-06-23 ES ES04776989T patent/ES2403601T3/es not_active Expired - Lifetime
- 2004-06-23 WO PCT/US2004/020163 patent/WO2005023220A1/en active Application Filing
- 2004-06-23 ES ES12161556.1T patent/ES2566681T3/es not_active Expired - Lifetime
- 2004-06-23 EP EP04776989A patent/EP1660041B1/en not_active Expired - Lifetime
- 2004-06-23 BR BRPI0413889-9A patent/BRPI0413889A/pt active Search and Examination
2005
- 2005-12-09 US US11/298,729 patent/US7354599B2/en not_active Expired - Lifetime
2006
- 2006-02-20 IL IL173808A patent/IL173808A/en active IP Right Grant
- 2006-03-20 US US11/384,767 patent/US20060159740A1/en not_active Abandoned
2010
- 2010-02-16 IL IL203995A patent/IL203995A/en active IP Right Grant
2011
- 2011-07-01 JP JP2011147503A patent/JP5639014B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US20060088584A1 (en)	2006-04-27
PL2471512T3 (pl)	2016-08-31
CA2746516A1 (en)	2005-03-17
CN1842322B (zh)	2011-05-04
HUE026790T2 (en)	2016-07-28
KR100975160B1 (ko)	2010-08-10
JP4869929B2 (ja)	2012-02-08
ES2566681T3 (es)	2016-04-14
CN1842322A (zh)	2006-10-04
RU2006109497A (ru)	2007-10-10
US7354599B2 (en)	2008-04-08
EP1660041A1 (en)	2006-05-31
JP2011213731A (ja)	2011-10-27
ES2403601T3 (es)	2013-05-20
CA2536977A1 (en)	2005-03-17
US20060159740A1 (en)	2006-07-20
BRPI0413889A (pt)	2006-10-24
KR20060039451A (ko)	2006-05-08
EP1660041B1 (en)	2013-03-06
KR100973064B1 (ko)	2010-08-17
AU2004270119A1 (en)	2005-03-17
IL203995A (en)	2017-05-29
EP2471512A2 (en)	2012-07-04
PT1660041E (pt)	2013-05-15
JP5639014B2 (ja)	2014-12-10
WO2005023220A1 (en)	2005-03-17
EP1660041A4 (en)	2010-01-27
CA2536977C (en)	2011-10-11
KR20080027974A (ko)	2008-03-28
KR20080110685A (ko)	2008-12-18
IL173808A0 (en)	2006-07-05
CA2746516C (en)	2013-05-07
DK2471512T3 (da)	2016-04-04
KR100887785B1 (ko)	2009-03-09
US20050048109A1 (en)	2005-03-03
IL173808A (en)	2015-11-30
EP2471512A3 (en)	2012-07-11
AU2004270119B2 (en)	2008-06-05
PL1660041T3 (pl)	2013-08-30
JP2007503436A (ja)	2007-02-22
RU2343904C2 (ru)	2009-01-20
EP2471512B1 (en)	2016-03-16

Publication	Publication Date	Title
DK1660041T3 (da)	2013-06-03	Ikke-polær fotosensibilisator til fotodynamisk terapi
NO20035349D0 (no)	2003-12-01	Fotodynamisk terapilampe
IS7670A (is)	2005-01-27	Samsett meðferð fyrir offjölgunar sjúkdóma
NO20052914D0 (no)	2005-06-15	Terapeutiske forbindelser
EP1599196A4 (en)	2006-05-31	COMBINATION THERAPIES FOR CANCER TREATMENT
ATE512965T1 (de)	2011-07-15	Pyrrolopyrimidin derivate
EE05505B1 (et)	2012-02-15	Personaalne teraapiasektsioon
AU2003224654A1 (en)	2003-09-29	Photodynamic therapy for pre-melanomas
DE602004017558D1 (de)	2008-12-18	Endoskop mit ultravioletter Bestrahlung
EP1711145A4 (en)	2010-02-10	PHOTOTHERAPY DEVICE
AU2003900176A0 (en)	2003-01-30	Photodynamic therapy light source
DK1740269T3 (da)	2013-11-04	Lysterapiindretning
DK1694122T3 (da)	2007-12-03	N-arylhydrazonderivater til fröbehandling
EP1570270A4 (en)	2010-09-22	THERAPEUTIC BIOKON JUGATE
DK1597171T3 (da)	2013-02-11	Terapeutisk mikroskum
NL1024677A1 (nl)	2004-05-06	Therapeutische prolinederivaten.
ATA13602003A (de)	2005-04-15	Therapeutisches behandlungsgerät
DK1553950T3 (da)	2007-10-15	Terapeutisk behandling
NO20050689L (no)	2005-03-21	Terapeutisk anvendelse
EP1808198A4 (en)	2010-04-21	PHOTODYNAMIC THERAPY DEVICE
AU2003301267A8 (en)	2004-05-04	Photodynamic therapy for ocular neovascularization
DE60328516D1 (de)	2009-09-03	Thia-epothilon derivate zur krebsbehandlung
NO20055449D0 (no)	2005-11-17	Fremgangsmate for diagnostisering av behandling av kreft
DK1618130T3 (da)	2013-06-24	Terapeutisk cancervaccine
NO20053189D0 (no)	2005-06-29	HVC-kombinasjonsterapi.