Nothing Special   »   [go: up one dir, main page]

DK1356067T3 - Fremgangsmåde til fremstilling af polyumættede fedtsyrer, nye biosyntesegener samt nye vegetabilske ekspressionskonstrukter - Google Patents

Fremgangsmåde til fremstilling af polyumættede fedtsyrer, nye biosyntesegener samt nye vegetabilske ekspressionskonstrukter

Info

Publication number
DK1356067T3
DK1356067T3 DK02704657.2T DK02704657T DK1356067T3 DK 1356067 T3 DK1356067 T3 DK 1356067T3 DK 02704657 T DK02704657 T DK 02704657T DK 1356067 T3 DK1356067 T3 DK 1356067T3
Authority
DK
Denmark
Prior art keywords
fatty acids
new
production
genes
polyunsaturated fatty
Prior art date
Application number
DK02704657.2T
Other languages
English (en)
Inventor
Jens Lerchl
Andreas Renz
Ernst Heinz
Frederic Domergue
Ulrich Zaehringer
Original Assignee
Basf Plant Science Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Plant Science Gmbh filed Critical Basf Plant Science Gmbh
Application granted granted Critical
Publication of DK1356067T3 publication Critical patent/DK1356067T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432Eicosapentaenoic acids [EPA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434Docosahexenoic acids [DHA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK02704657.2T 2001-01-19 2002-01-18 Fremgangsmåde til fremstilling af polyumættede fedtsyrer, nye biosyntesegener samt nye vegetabilske ekspressionskonstrukter DK1356067T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10102337A DE10102337A1 (de) 2001-01-19 2001-01-19 Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte
PCT/EP2002/000462 WO2002057465A2 (de) 2001-01-19 2002-01-18 Verfahren zur herstellung mehrfach ungesaettigter fettsaeuren, neue biosynthesegene sowie neue pflanzliche expressionskonstrukte

Publications (1)

Publication Number Publication Date
DK1356067T3 true DK1356067T3 (da) 2010-08-16

Family

ID=7671106

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02704657.2T DK1356067T3 (da) 2001-01-19 2002-01-18 Fremgangsmåde til fremstilling af polyumættede fedtsyrer, nye biosyntesegener samt nye vegetabilske ekspressionskonstrukter

Country Status (11)

Country Link
US (3) US7615679B2 (da)
EP (1) EP1356067B1 (da)
JP (1) JP4490039B2 (da)
AT (1) ATE466091T1 (da)
BR (1) BR0206598A (da)
CA (1) CA2435081C (da)
DE (2) DE10102337A1 (da)
DK (1) DK1356067T3 (da)
ES (1) ES2345324T3 (da)
NO (1) NO20033239L (da)
WO (1) WO2002057465A2 (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10102338A1 (de) * 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Expression von Biosynthesegenen in pflanzlichen Samen unter Verwendung von neuen multiplen Expressionskonstrukten
US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
PT2172536T (pt) 2003-08-01 2016-08-17 Basf Plant Science Gmbh Processo para a produção de ácidos gordos poli-insaturados em organismos transgénicos
MY140210A (en) * 2003-12-22 2009-11-30 Suntory Holdings Ltd Marchantiales-derived unsaturated fatty acid synthetase genes and use of the same
EP1918367B1 (en) * 2004-02-17 2011-07-06 The University of York Desaturase Enzymes
EP2623584B1 (de) 2004-02-27 2019-04-10 BASF Plant Science GmbH Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Pflanzen
CA2558726C (en) 2004-02-27 2017-11-07 Basf Plant Science Gmbh Method for producing unsaturated .omega.-3-fatty acids in transgenic organisms
EP2363492A3 (en) 2004-04-22 2012-03-14 Commonwealth Scientific and Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells.
US7807849B2 (en) * 2004-04-22 2010-10-05 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
NZ552254A (en) * 2004-06-04 2008-12-24 Fluxone Sciences As Metabolically engineered cells for the production of polyunsaturated fatty acids
FI20041240A0 (fi) * 2004-09-27 2004-09-27 Raisio Yhtymae Oyj Menetelmä rasvahappojen esteröimiseksi
US7588931B2 (en) * 2004-11-04 2009-09-15 E. I. Du Pont De Nemours And Company High arachidonic acid producing strains of Yarrowia lipolytica
AU2006219823A1 (en) * 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
ES2550623T3 (es) * 2005-05-23 2015-11-11 Blue Horse Labs, Inc. Cártamo con ácido gamma linolénico elevado
US7723574B2 (en) 2005-11-24 2010-05-25 Basf Plant Science Gmbh Process for the production of Δ5-unsaturated fatty acids in transgenic organisms
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
US7678560B2 (en) * 2006-05-17 2010-03-16 E.I. Du Pont De Nemours And Company Δ 5 desaturase and its use in making polyunsaturated fatty acids
CN101578363A (zh) 2006-08-29 2009-11-11 联邦科学技术研究组织 脂肪酸的合成
ES2531391T3 (es) 2006-10-06 2015-03-13 Basf Plant Science Gmbh Delta-5 desaturasas y procedimiento para la preparación de ácidos grasos poliinsaturados en organismos transgénicos no humanos
HUE028692T2 (en) * 2007-04-03 2016-12-28 Du Pont Multi-uses and their use in the production of polyunsaturated fatty acids
WO2009124225A1 (en) * 2008-04-03 2009-10-08 E. I. Du Pont De Nemours And Company Multizymes
US8853383B2 (en) 2008-07-01 2014-10-07 Basf Plant Science Gmbh Promoters from Brassica napus for seed specific gene expression
DE112009002048T5 (de) * 2008-08-26 2012-01-26 Basf Plant Science Gmbh Nukleinsäure, die Desaturasen kodieren, und modifiziertes Planzenöl
CA2743880C (en) * 2008-11-18 2020-08-18 James Robertson Petrie Recombinant cells comprising exogenous a5 elongase and methods for producing docosapentaenoic acid
US8822662B2 (en) 2008-12-12 2014-09-02 Basf Plant Science Company Gmbh Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms
EP2821492A3 (en) 2009-05-13 2015-04-08 BASF Plant Science Company GmbH Acyltransferases and uses thereof in fatty acid production
US8993841B2 (en) 2009-06-08 2015-03-31 Basf Plant Science Company Gmbh Fatty acid elongation components and uses thereof
AU2010272536B2 (en) 2009-07-17 2016-09-08 Basf Plant Science Company Gmbh Novel fatty acid desaturases and elongases and uses thereof
EP2473609B1 (en) 2009-08-31 2016-10-12 BASF Plant Science Company GmbH Regulatory nucleic acid molecules for enhancing seed-specific gene expression in plants promoting enhanced polyunsaturated fatty acid synthesis
US9347049B2 (en) 2009-11-24 2016-05-24 Basf Plant Science Company Gmbh Fatty acid elongase and uses thereof
EP2504427B1 (en) 2009-11-24 2018-06-27 BASF Plant Science Company GmbH Novel fatty acid desaturase and uses thereof
AU2011269059B2 (en) 2010-06-25 2016-01-28 Basf Plant Science Company Gmbh Acyltransferases and uses therof in fatty acid production
EP2630235B1 (en) 2010-10-21 2017-04-05 BASF Plant Science Company GmbH Novel fatty acid desaturases, elongases, elongation components and uses therof
JP6157008B2 (ja) 2011-06-16 2017-07-05 フィリップス ライティング ホールディング ビー ヴィ 符号化光を用いたロバストな昼光統合
MX351174B (es) * 2011-07-21 2017-10-04 Dsm Ip Assets Bv Microorganismos que producen acido eicosapentaenoico, composiciones de acidos grasos,y metodos para prepararlos y usos de los mismos.
BR122019026149A8 (pt) 2012-06-15 2022-06-28 Commw Scient Ind Res Org Célula hospedeira, processo de produzir um lipídio de planta extraído, método de produzir semente, farinha de semente, método para produzir um produto alimentício, uso e processo para produzir ésteres de etila
WO2014020533A2 (en) 2012-08-03 2014-02-06 Basf Plant Science Company Gmbh Novel enzymes, enzyme components and uses thereof
CN102787128A (zh) * 2012-08-28 2012-11-21 江南大学 一种用于多不饱和脂肪酸生物合成的脱饱和酶Δ9 Des
EP3083949B1 (en) 2013-12-17 2020-02-12 BASF Plant Science Company GmbH Methods for conversion of the substrate specificity of desaturases
CA3241340A1 (en) 2013-12-18 2015-06-25 Grains Research And Development Corporation Lipid comprising long chain polyunsaturated fatty acids
KR102527795B1 (ko) 2014-06-27 2023-05-02 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 도코사펜타에노산을 포함하는 지질
DE102016204033A1 (de) 2016-03-11 2017-09-14 Universität Rostock Maßnahmen und Methoden zur Schadtierbekämpfung
DE102016204700A1 (de) 2016-03-22 2017-09-28 Universität Rostock Rekombinante Herstellung von Subfatin
US10920238B2 (en) 2016-06-01 2021-02-16 National Research Council Of Canada Winter aconite fatty acid elongase and uses thereof in the production of fatty acids

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69133261D1 (de) 1990-03-16 2003-06-26 Calgene Llc Davis Dnas, die für pflanzliche desaturasen kodieren und deren anwendungen
PH31293A (en) 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
US5614393A (en) 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
AU675923B2 (en) 1991-12-04 1997-02-27 E.I. Du Pont De Nemours And Company Fatty acid desaturase genes from plants
CA2084348A1 (en) 1991-12-31 1993-07-01 David F. Hildebrand Fatty acid alteration by a d9 desaturase in transgenic plant tissue
DE69333025T2 (de) 1992-11-17 2004-04-29 E.I. Du Pont De Nemours And Co., Wilmington Für mikrosom delta 12 fettsäuredesaturase kodierende gene und verwandte enzyme von pflanzen
WO1994018337A1 (en) 1993-02-05 1994-08-18 Monsanto Company Altered linolenic and linoleic acid content in plants
NZ277562A (en) 1993-12-28 1997-12-19 Kirin Brewery Gene encoding a protein that desaturates lipid bound fatty acids at the delta 9 position
US6310194B1 (en) 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases
US5654402A (en) 1994-10-26 1997-08-05 Michigan State University Methods and compositions relating to plant Δ6 palmitoyl-acyl carrier protein desaturase
EP1714543B1 (en) 1995-12-14 2011-08-17 Cargill, Incorporated Plants having mutant sequences that confer altered fatty acid profiles
EP0794250A1 (en) 1996-03-04 1997-09-10 Soremartec S.A. Isolation and sequencing of the hazel FAd2-N gene
US5972664A (en) * 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
GB9724783D0 (en) 1997-11-24 1998-01-21 Inst Arable Crops Research Novel polypeptides
DE10102338A1 (de) * 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Expression von Biosynthesegenen in pflanzlichen Samen unter Verwendung von neuen multiplen Expressionskonstrukten

Also Published As

Publication number Publication date
WO2002057465A2 (de) 2002-07-25
WO2002057465A3 (de) 2003-06-12
ATE466091T1 (de) 2010-05-15
EP1356067A2 (de) 2003-10-29
DE50214395D1 (de) 2010-06-10
EP1356067B1 (de) 2010-04-28
US20100021976A1 (en) 2010-01-28
BR0206598A (pt) 2004-06-22
US7615679B2 (en) 2009-11-10
US8729337B2 (en) 2014-05-20
US8088974B2 (en) 2012-01-03
NO20033239L (no) 2003-09-16
JP2004530418A (ja) 2004-10-07
CA2435081C (en) 2016-02-23
ES2345324T3 (es) 2010-09-21
JP4490039B2 (ja) 2010-06-23
US20040053379A1 (en) 2004-03-18
NO20033239D0 (no) 2003-07-17
US20120210465A1 (en) 2012-08-16
DE10102337A1 (de) 2002-07-25
CA2435081A1 (en) 2002-07-25

Similar Documents

Publication Publication Date Title
DK1356067T3 (da) Fremgangsmåde til fremstilling af polyumættede fedtsyrer, nye biosyntesegener samt nye vegetabilske ekspressionskonstrukter
Meyer et al. Novel fatty acid elongases and their use for the reconstitution of docosahexaenoic acid biosynthesis
AU2008236595B2 (en) Delta-8 desaturases and their use in making polyunsaturated fatty acids
BRPI0410510A (pt) moléculas de ácido nucléico isolada, gene quimérico, yarrowia sp. transformada, métodos de produção de ácidos y-linolênico, estearidÈnico, eicosatetraenóico, eicosapentaenóico, di-homo-y-linoléico, docosapentaenóico, método de otimização de um gene, métodos de otimização da expressão de um gene e óleo microbiano
CA2120629C (en) Production of gamma linolenic acid by a .delta.6-desaturase
EP2137304B1 (en) Delta 9 elongases and their use in making polyunsaturated fatty acids
IL162991A (en) Isolated nucleic acid sequences which encode polypeptide having delta-6-desaturase activity, amino acid sequences, gene constructs, vectors, transgenic non human organisms and methods for production of pufa
EP2259674B1 (en) Delta-4 desaturase and its use in making polyunsaturated fatty acids
IL146782A0 (en) 6-acetylenase and 6-desaturase from ceratodon purpureus
WO2005047479A3 (en) Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast
WO2005047485A3 (en) Delta12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast
WO2004104167A3 (en) A δ-12 desaturase gene suitable for altering levels of polyunsaturated fatty acids in oleaginous yeasts
HUP0300081A2 (en) Novel elongase gene and method for producing multiple-unsaturated fatty acids
RU2007127798A (ru) Способ получения полиненасыщенных жирных кислот в трансгенных организмах
BRPI0913714A2 (pt) polipeptídeo mutante que possui atividade de a5 dessaturase, molécula de ácido nucleico isolada, célula hospedeira microbiana e métodos de produção de ácido araquidônico e de ácido eicosapentaenoico
CA2435685A1 (en) Desaturase genes and uses thereof
IL162794A0 (en) Novel elongase gene and method for producing polyunsaturated fatty acids
RU2011114558A (ru) Гены δ-8-десатуразы, ферменты, кодируемые ими, и их применение
Kim et al. Heterologous Reconstitution of Omega‐3 Polyunsaturated Fatty Acids in Arabidopsis
KR101549147B1 (ko) 고도불포화지방산 생합성을 위한 재조합 벡터 및 이를 이용하여 제작된 형질전환 효모
Soltani et al. Isolation and Characterization of Delta 15 Desaturase (FAD3) Gene From Camelina sativa L.
UA86340C2 (ru) Новый ген элонгазы и способ получения полиненасыщенных кислот жирного ряда